SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PDG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_B_GBNB914_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 5k8b 8-AMINO-3,8-DIDEOXY-
ALPHA-D-MANNO-OCTULO
SONATE TRANSAMINASE
(Shewanella
oneidensis) 		5 / 10 GLY A 193
GLY A  61
THR A  62
ALA A  63
ALA A  64
 None
PDG  A 501 (-3.4A)
PDG  A 501 (-3.7A)
None
None
 0.83A 2ej3B-5k8bA:
undetectable		 2ej3B-5k8bA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 5k8b 8-AMINO-3,8-DIDEOXY-
ALPHA-D-MANNO-OCTULO
SONATE TRANSAMINASE
(Shewanella
oneidensis) 		4 / 4 PRO A   2
THR A 187
GLY A  61
THR A  62
 None
None
PDG  A 501 (-3.4A)
PDG  A 501 (-3.7A)
 1.12A 3ib1A-5k8bA:
0.7		 3ib1A-5k8bA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 4ce5 AT-OMEGATA
(Aspergillus
terreus) 		5 / 11 GLY A 123
ARG A 122
LEU A  58
GLY A  52
ALA A 276
 None
None
None
None
PDG  A1181 ( 3.7A)
 1.16A 4l6v1-4ce5A:
undetectable
4l6v6-4ce5A:
undetectable		 4l6v1-4ce5A:
17.52
4l6v6-4ce5A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4ce5 AT-OMEGATA
(Aspergillus
terreus) 		5 / 12 GLY A 214
GLY A 216
LEU A 211
ILE A 270
LEU A 285
 None
PDG  A1181 (-3.2A)
None
None
None
 0.98A 4n49A-4ce5A:
undetectable		 4n49A-4ce5A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 5k8b 8-AMINO-3,8-DIDEOXY-
ALPHA-D-MANNO-OCTULO
SONATE TRANSAMINASE
(Shewanella
oneidensis) 		5 / 12 MET A  42
ALA A  55
LEU A 248
ILE A 188
CYH A 159
 None
None
None
None
PDG  A 501 (-3.7A)
 1.29A 5vlmG-5k8bA:
undetectable		 5vlmG-5k8bA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 5k8b 8-AMINO-3,8-DIDEOXY-
ALPHA-D-MANNO-OCTULO
SONATE TRANSAMINASE
(Shewanella
oneidensis) 		5 / 12 ILE A 162
PHE A 182
GLY A  61
ALA A  64
ILE A 197
 None
None
PDG  A 501 (-3.4A)
None
None
 1.02A 6dwnD-5k8bA:
undetectable		 6dwnD-5k8bA:
12.54