SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PCQ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_A_LDPA297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 9 PHE A  23
PRO A  46
PHE A  80
LYS A 105
HIS A 107
 PCQ  A 712 ( 4.6A)
PCQ  A 712 ( 4.3A)
PCQ  A 712 (-4.6A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
 0.63A 2a3rA-1g3mA:
43.2		 2a3rA-1g3mA:
49.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_A_LDPA297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 9 PRO A  46
PHE A  80
LYS A 105
HIS A 107
HIS A 148
 PCQ  A 712 ( 4.3A)
PCQ  A 712 (-4.6A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
None
 0.62A 2a3rA-1g3mA:
43.2		 2a3rA-1g3mA:
49.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_B_LDPB297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 9 PHE A  23
PRO A  46
PHE A  80
LYS A 105
HIS A 107
 PCQ  A 712 ( 4.6A)
PCQ  A 712 ( 4.3A)
PCQ  A 712 (-4.6A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
 0.62A 2a3rB-1g3mA:
43.3		 2a3rB-1g3mA:
49.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3R_B_LDPB297_1
(MONOAMINE-SULFATING
PHENOL
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		5 / 9 PRO A  46
PHE A  80
LYS A 105
HIS A 107
HIS A 148
 PCQ  A 712 ( 4.3A)
PCQ  A 712 (-4.6A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
None
 0.62A 2a3rB-1g3mA:
43.3		 2a3rB-1g3mA:
49.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		7 / 10 PHE A  23
PRO A  46
LYS A  47
LYS A 105
HIS A 107
PHE A 141
MET A 247
 PCQ  A 712 ( 4.6A)
PCQ  A 712 ( 4.3A)
A3P  A 701 (-2.7A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.7A)
None
 0.62A 2d06A-1g3mA:
43.3		 2d06A-1g3mA:
50.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		7 / 10 PHE A  23
PRO A  46
LYS A 105
HIS A 107
PHE A 141
TYR A 239
MET A 247
 PCQ  A 712 ( 4.6A)
PCQ  A 712 ( 4.3A)
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.7A)
PCQ  A 712 ( 4.6A)
None
 0.62A 2d06B-1g3mA:
43.1		 2d06B-1g3mA:
50.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		8 / 9 TYR A  20
PHE A  80
CYH A  83
LYS A 105
HIS A 107
PHE A 141
ILE A 246
MET A 247
 PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.6A)
None
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.7A)
PCQ  A 712 (-4.3A)
None
 0.24A 4jvlA-1g3mA:
50.3		 4jvlA-1g3mA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JVL_B_ESTB302_1
(ESTROGEN
SULFOTRANSFERASE)		 1g3m ESTROGEN
SULFOTRANSFERASE
(Homo
sapiens) 		8 / 9 TYR A  20
PHE A  80
CYH A  83
LYS A 105
HIS A 107
PHE A 141
ILE A 246
MET A 247
 PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.6A)
None
PCQ  A 712 (-3.0A)
PCQ  A 712 (-3.9A)
PCQ  A 712 (-4.7A)
PCQ  A 712 (-4.3A)
None
 0.24A 4jvlB-1g3mA:
49.3		 4jvlB-1g3mA:
99.66