SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PC0'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.72A 1fk9A-2hnzA:
41.7
1fk9A-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
1.47A 1fk9A-2hnzA:
41.7
1fk9A-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 LYS A 101
LYS A 103
VAL A 106
VAL A 179
GLY A 190
None
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
1.09A 1fk9A-2hnzA:
41.7
1fk9A-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 LYS A 101
LYS A 103
VAL A 179
TYR A 181
GLY A 190
None
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
1.19A 1fk9A-2hnzA:
41.7
1fk9A-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 188
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.67A 1fkoA-2hnzA:
36.4
1fkoA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
1.20A 1fkoA-2hnzA:
36.4
1fkoA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 11 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
1.33A 1fkpA-2hnzA:
35.9
1fkpA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 11 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.54A 1fkpA-2hnzA:
35.9
1fkpA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.73A 1ikvA-2hnzA:
37.5
1ikvA-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 9 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
1.46A 1ikvA-2hnzA:
37.5
1ikvA-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
10 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.76A 1ikwA-2hnzA:
37.6
1ikwA-2hnzA:
98.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 10 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
1.47A 1ikwA-2hnzA:
37.6
1ikwA-2hnzA:
98.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 11 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 188
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.65A 1jkhA-2hnzA:
35.7
1jkhB-2hnzA:
13.9
1jkhA-2hnzA:
99.07
1jkhB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 11 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
1.26A 1jkhA-2hnzA:
35.7
1jkhB-2hnzA:
13.9
1jkhA-2hnzA:
99.07
1jkhB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 8 LEU A 100
VAL A 106
TYR A 188
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.52A 1jlbA-2hnzA:
35.1
1jlbA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
4 / 8 LEU A 100
TYR A 181
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.66A 1jlfA-2hnzA:
35.4
1jlfB-2hnzA:
20.8
1jlfA-2hnzA:
99.07
1jlfB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 8 LEU A 100
VAL A 106
TYR A 181
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
0.55A 1jlfA-2hnzA:
35.4
1jlfB-2hnzA:
20.8
1jlfA-2hnzA:
99.07
1jlfB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 11 LEU A 100
LYS A 102
PRO A 226
PHE A 227
LEU A 234
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
1.27A 1klmA-2hnzA:
35.7
1klmA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 11 LEU A 100
LYS A 102
TYR A 181
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
1.33A 1klmA-2hnzA:
35.7
1klmA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 11 LEU A 100
LYS A 102
VAL A 106
TYR A 181
TYR A 188
PRO A 226
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.95A 1klmA-2hnzA:
35.7
1klmA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KLM_A_SPPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 11 LEU A 100
LYS A 102
VAL A 106
TYR A 181
TYR A 188
PRO A 226
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.93A 1klmA-2hnzA:
35.7
1klmA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
10 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.73A 1lw0A-2hnzA:
41.4
1lw0A-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
1.49A 1lw0A-2hnzA:
41.4
1lw0A-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
11 / 11 PRO A  95
LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.72A 1lwcA-2hnzA:
41.5
1lwcA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 7 LEU A 100
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
0.33A 1lweA-2hnzA:
34.2
1lweA-2hnzA:
98.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.55A 1lwfA-2hnzA:
35.2
1lwfA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 9 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
1.24A 1lwfA-2hnzA:
35.2
1lwfA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 9 VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
1.49A 1lwfA-2hnzA:
35.2
1lwfA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 10 LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.77A 1s1uA-2hnzA:
41.1
1s1uA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 LYS A 103
VAL A 179
TYR A 181
GLY A 190
TYR A 318
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
1.35A 1s1uA-2hnzA:
41.1
1s1uA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 8 LEU A 100
VAL A 106
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.57A 1s1xA-2hnzA:
35.7
1s1xA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 10 LEU A 100
LYS A 101
PRO A 226
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
1.14A 1sv5A-2hnzA:
35.6
1sv5A-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 10 LEU A 100
LYS A 101
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.88A 1sv5A-2hnzA:
35.6
1sv5A-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 10 LEU A 100
LYS A 101
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
0.99A 1sv5A-2hnzA:
35.6
1sv5A-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 TYR A 181
PRO A 225
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.96A 1sv5A-2hnzA:
35.6
1sv5A-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VRT_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.69A 1vrtA-2hnzA:
41.1
1vrtA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
10 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.71A 2hndA-2hnzA:
42.3
2hndA-2hnzA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
10 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.77A 2hnyA-2hnzA:
42.3
2hnyA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
0.82A 2zd1A-2hnzA:
36.1
2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
0.92A 2zd1A-2hnzA:
36.1
2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
0.79A 2zd1A-2hnzA:
36.1
2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
0.90A 2zd1A-2hnzA:
36.1
2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.74A 2zd1A-2hnzA:
36.1
2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.90A 2zd1A-2hnzA:
36.1
2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.73A 2zd1A-2hnzA:
36.1
2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZD1_A_T27A557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.87A 2zd1A-2hnzA:
36.1
2zd1A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 PRO A  95
PRO A 226
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
1.24A 2ze2A-2hnzA:
35.3
2ze2A-2hnzA:
98.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 PRO A  95
TYR A 181
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.71A 2ze2A-2hnzA:
35.3
2ze2A-2hnzA:
98.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 PRO A  95
VAL A 179
TYR A 181
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.80A 2ze2A-2hnzA:
35.3
2ze2A-2hnzA:
98.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 TYR A 181
TYR A 188
PRO A 225
LEU A 234
TYR A 318
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.81A 2ze2A-2hnzA:
35.3
2ze2A-2hnzA:
98.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZE2_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 VAL A 179
TYR A 181
TYR A 188
PRO A 225
TYR A 318
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
0.86A 2ze2A-2hnzA:
35.3
2ze2A-2hnzA:
98.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 11 LEU A 100
TYR A 188
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
1.06A 3bgrA-2hnzA:
35.2
3bgrB-2hnzA:
14.1
3bgrA-2hnzA:
98.13
3bgrB-2hnzA:
98.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 11 LEU A 100
VAL A 179
TYR A 188
PHE A 227
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
1.08A 3bgrA-2hnzA:
35.2
3bgrB-2hnzA:
14.1
3bgrA-2hnzA:
98.13
3bgrB-2hnzA:
98.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 9 LEU A 100
LYS A 103
TYR A 181
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
1.47A 3hvtA-2hnzA:
14.5
3hvtA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 9 LEU A 100
LYS A 103
VAL A 106
TYR A 181
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.72A 3hvtA-2hnzA:
14.5
3hvtA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 9 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
0.77A 3hvtA-2hnzA:
14.5
3hvtA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HVT_A_NVPA557_1
(HIV-1 REVERSE
TRANSCRIPTASE
(SUBUNIT P66))
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 9 LYS A 103
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TRP A 229
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
1.43A 3hvtA-2hnzA:
14.5
3hvtA-2hnzA:
98.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LP0_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.64A 3lp0A-2hnzA:
37.5
3lp0A-2hnzA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LP0_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 9 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
0.76A 3lp0A-2hnzA:
37.5
3lp0A-2hnzA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.75A 3lp1A-2hnzA:
37.9
3lp1A-2hnzA:
99.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 11 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.73A 3m8pA-2hnzA:
37.9
3m8pB-2hnzA:
14.4
3m8pA-2hnzA:
99.26
3m8pB-2hnzA:
99.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 11 LYS A 103
VAL A 106
VAL A 179
PHE A 227
TYR A 318
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
0.90A 3m8pA-2hnzA:
37.9
3m8pB-2hnzA:
14.4
3m8pA-2hnzA:
99.26
3m8pB-2hnzA:
99.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
GLY A 190
TRP A 229
LEU A 234
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.82A 3mecA-2hnzA:
38.1
3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.69A 3mecA-2hnzA:
38.1
3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
GLY A 190
LEU A 234
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.68A 3mecA-2hnzA:
38.1
3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.54A 3mecA-2hnzA:
38.1
3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LYS A 103
VAL A 106
VAL A 179
GLY A 190
PHE A 227
LEU A 234
PRO A 236
TYR A 318
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.93A 3mecA-2hnzA:
38.1
3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 12 LYS A 103
VAL A 179
TYR A 181
GLY A 190
PRO A 236
TYR A 318
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
1.22A 3mecA-2hnzA:
38.1
3mecA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
TYR A 188
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.66A 3medA-2hnzA:
38.1
3medB-2hnzA:
14.4
3medA-2hnzA:
99.07
3medB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.50A 3medA-2hnzA:
38.1
3medB-2hnzA:
14.4
3medA-2hnzA:
99.07
3medB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 12 VAL A 106
VAL A 179
GLY A 190
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.89A 3medA-2hnzA:
38.1
3medB-2hnzA:
14.4
3medA-2hnzA:
99.07
3medB-2hnzA:
98.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 12 LEU A 100
LYS A 103
VAL A 179
TYR A 181
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.3A)
1.34A 3meeA-2hnzA:
38.2
3meeA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
10 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.67A 3meeA-2hnzA:
38.2
3meeA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
10 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.65A 3meeA-2hnzA:
38.2
3meeA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.72A 3megA-2hnzA:
38.1
3megA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.69A 3megA-2hnzA:
38.1
3megA-2hnzA:
99.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.73A 3qipA-2hnzA:
38.5
3qipA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QIP_A_NVPA561_1
(REVERSE HIV-1
REVERSE
TRANSCRIPTASE P66)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.83A 3qipA-2hnzA:
38.5
3qipA-2hnzA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 12 LEU A 100
LYS A 103
TYR A 188
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
1.33A 3qlhA-2hnzA:
35.9
3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.92A 3qlhA-2hnzA:
35.9
3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
1.01A 3qlhA-2hnzA:
35.9
3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.90A 3qlhA-2hnzA:
35.9
3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLH_A_T27A555_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.89A 3qlhA-2hnzA:
35.9
3qlhA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 8 LEU A 100
LYS A 103
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.80A 3v81A-2hnzA:
35.6
3v81A-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 8 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.66A 3v81C-2hnzA:
36.6
3v81C-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3O_A_EFZA1557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 9 LEU A 100
LYS A 101
LYS A 103
VAL A 106
TYR A 181
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.82A 4b3oA-2hnzA:
34.0
4b3oA-2hnzA:
98.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3O_A_EFZA1557_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 9 LEU A 100
LYS A 101
LYS A 103
VAL A 106
TYR A 181
TYR A 188
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
None
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
0.83A 4b3oA-2hnzA:
34.0
4b3oA-2hnzA:
98.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 7 LEU A 100
LYS A 103
VAL A 106
TYR A 181
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.88A 4b3qA-2hnzA:
31.5
4b3qA-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 7 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.3A)
0.87A 4b3qA-2hnzA:
31.5
4b3qA-2hnzA:
97.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.81A 4g1qA-2hnzA:
36.1
4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.96A 4g1qA-2hnzA:
36.1
4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.76A 4g1qA-2hnzA:
36.1
4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.92A 4g1qA-2hnzA:
36.1
4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.80A 4g1qA-2hnzA:
36.1
4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.89A 4g1qA-2hnzA:
36.1
4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.77A 4g1qA-2hnzA:
36.1
4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G1Q_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.85A 4g1qA-2hnzA:
36.1
4g1qA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
0.82A 4iclA-2hnzA:
36.2
4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
0.91A 4iclA-2hnzA:
36.2
4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
0.80A 4iclA-2hnzA:
36.2
4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
0.90A 4iclA-2hnzA:
36.2
4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.71A 4iclA-2hnzA:
36.2
4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.85A 4iclA-2hnzA:
36.2
4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.71A 4iclA-2hnzA:
36.2
4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ICL_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.84A 4iclA-2hnzA:
36.2
4iclA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.81A 4id5A-2hnzA:
36.1
4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.91A 4id5A-2hnzA:
36.1
4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.76A 4id5A-2hnzA:
36.1
4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.87A 4id5A-2hnzA:
36.1
4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.75A 4id5A-2hnzA:
36.1
4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.84A 4id5A-2hnzA:
36.1
4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.71A 4id5A-2hnzA:
36.1
4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ID5_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.80A 4id5A-2hnzA:
36.1
4id5A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
0.76A 4idkA-2hnzA:
36.1
4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
0.86A 4idkA-2hnzA:
36.1
4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.3A)
0.75A 4idkA-2hnzA:
36.1
4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.3A)
0.85A 4idkA-2hnzA:
36.1
4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.67A 4idkA-2hnzA:
36.1
4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.78A 4idkA-2hnzA:
36.1
4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.67A 4idkA-2hnzA:
36.1
4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IDK_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.77A 4idkA-2hnzA:
36.1
4idkA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.80A 4ifvA-2hnzA:
36.0
4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.87A 4ifvA-2hnzA:
36.0
4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.75A 4ifvA-2hnzA:
36.0
4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.82A 4ifvA-2hnzA:
36.0
4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.74A 4ifvA-2hnzA:
36.0
4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.83A 4ifvA-2hnzA:
36.0
4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.68A 4ifvA-2hnzA:
36.0
4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFV_A_T27A601_1
(EXORIBONUCLEASE H,
P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.79A 4ifvA-2hnzA:
36.0
4ifvA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.83A 4ifyA-2hnzA:
36.1
4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.90A 4ifyA-2hnzA:
36.1
4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.79A 4ifyA-2hnzA:
36.1
4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.87A 4ifyA-2hnzA:
36.1
4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.72A 4ifyA-2hnzA:
36.1
4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.84A 4ifyA-2hnzA:
36.1
4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.69A 4ifyA-2hnzA:
36.1
4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IFY_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.82A 4ifyA-2hnzA:
36.1
4ifyA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.83A 4ig3A-2hnzA:
36.1
4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.91A 4ig3A-2hnzA:
36.1
4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.77A 4ig3A-2hnzA:
36.1
4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.86A 4ig3A-2hnzA:
36.1
4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.78A 4ig3A-2hnzA:
36.1
4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.87A 4ig3A-2hnzA:
36.1
4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.72A 4ig3A-2hnzA:
36.1
4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IG3_A_T27A601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.82A 4ig3A-2hnzA:
36.1
4ig3A-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 12 LEU A 100
LYS A 103
TYR A 188
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
1.06A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.78A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.89A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.78A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PHE A 227
PRO A 236
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.90A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 12 LEU A 100
VAL A 179
TYR A 188
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
1.26A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.70A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.82A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.70A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFB_A_T27A607_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H,
EXORIBONUCLEA P66 RT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 236
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.3A)
PC0  A 999 (-4.3A)
0.84A 4kfbA-2hnzA:
36.1
4kfbA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PUO_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 9 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.77A 4puoA-2hnzA:
36.6
4puoA-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 8 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.67A 4puoC-2hnzA:
36.5
4puoC-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 8 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
0.80A 4pwdA-2hnzA:
36.2
4pwdA-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 8 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.61A 4pwdC-2hnzA:
36.6
4pwdC-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 8 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.63A 4pwdC-2hnzA:
36.6
4pwdC-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 8 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
0.72A 4q0bA-2hnzA:
36.0
4q0bA-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 8 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
0.72A 4q0bA-2hnzA:
36.0
4q0bA-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q0B_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 9 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.74A 4q0bC-2hnzA:
36.4
4q0bC-2hnzA:
98.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.86A 5cymA-2hnzA:
35.9
5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.92A 5cymA-2hnzA:
35.9
5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.85A 5cymA-2hnzA:
35.9
5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.93A 5cymA-2hnzA:
35.9
5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PHE A 227
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.72A 5cymA-2hnzA:
35.9
5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.86A 5cymA-2hnzA:
35.9
5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PHE A 227
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.73A 5cymA-2hnzA:
35.9
5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.85A 5cymA-2hnzA:
35.9
5cymA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.83A 5cyqA-2hnzA:
35.9
5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.91A 5cyqA-2hnzA:
35.9
5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.84A 5cyqA-2hnzA:
35.9
5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.94A 5cyqA-2hnzA:
35.9
5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PHE A 227
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.72A 5cyqA-2hnzA:
35.9
5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.80A 5cyqA-2hnzA:
35.9
5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PHE A 227
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.76A 5cyqA-2hnzA:
35.9
5cyqA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.82A 5cyqA-2hnzA:
35.9
5cyqA-2hnzA:
98.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
4 / 4 LEU A 234
TYR A 319
PRO A  95
ILE A  94
PC0  A 999 (-4.2A)
None
PC0  A 999 ( 4.9A)
None
1.42A 5esgA-2hnzA:
undetectable
5esgA-2hnzA:
21.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 11 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.66A 5hbmA-2hnzA:
37.5
5hbmA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 11 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.73A 5hbmA-2hnzA:
37.5
5hbmA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 11 PRO A  95
LYS A 103
VAL A 106
VAL A 179
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.83A 5hbmA-2hnzA:
37.5
5hbmA-2hnzA:
98.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.81A 6bsgA-2hnzA:
35.8
6bsgA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 10 LEU A 100
LYS A 103
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.83A 6bsgA-2hnzA:
35.8
6bsgA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
5 / 10 LEU A 100
LYS A 103
VAL A 179
TYR A 181
GLY A 190
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
1.46A 6bsgA-2hnzA:
35.8
6bsgA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 10 LEU A 100
LYS A 103
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.75A 6bsiA-2hnzA:
35.9
6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 10 LEU A 100
LYS A 103
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.89A 6bsiA-2hnzA:
35.9
6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 10 LEU A 100
LYS A 103
VAL A 106
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.81A 6bsiA-2hnzA:
35.9
6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 10 LEU A 100
LYS A 103
VAL A 106
TYR A 188
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
0.86A 6bsiA-2hnzA:
35.9
6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 10 LEU A 100
VAL A 106
VAL A 179
GLY A 190
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.64A 6bsiA-2hnzA:
35.9
6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
6 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 188
GLY A 190
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.3A)
0.72A 6bsiA-2hnzA:
35.9
6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 10 LEU A 100
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.58A 6bsiA-2hnzA:
35.9
6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 10 LEU A 100
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.74A 6bsiA-2hnzA:
35.9
6bsiA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
7 / 10 LEU A 100
LYS A 103
VAL A 106
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.97A 6bsjA-2hnzA:
35.5
6bsjA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 181
GLY A 190
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.66A 6bsjA-2hnzA:
35.5
6bsjA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 10 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
GLY A 190
TRP A 229
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
PC0  A 999 ( 4.8A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.3A)
0.72A 6bsjA-2hnzA:
35.5
6bsjA-2hnzA:
98.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 181
TYR A 188
PRO A 225
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.80A 6eliA-2hnzA:
36.5
6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
LYS A 103
VAL A 106
TYR A 188
PRO A 225
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.84A 6eliA-2hnzA:
36.5
6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 181
TYR A 188
PRO A 225
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.80A 6eliA-2hnzA:
36.5
6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
8 / 12 LEU A 100
VAL A 106
VAL A 179
TYR A 188
PRO A 225
PHE A 227
LEU A 234
TYR A 318
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-4.1A)
None
PC0  A 999 (-4.7A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.85A 6eliA-2hnzA:
36.5
6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
PRO A 225
PHE A 227
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.68A 6eliA-2hnzA:
36.5
6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
LYS A 103
VAL A 106
TYR A 181
PRO A 225
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
None
PC0  A 999 ( 4.8A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.76A 6eliA-2hnzA:
36.5
6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
PRO A 225
PHE A 227
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
None
PC0  A 999 (-4.7A)
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.68A 6eliA-2hnzA:
36.5
6eliA-2hnzA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)
2hnz REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H

(Human
immunodeficiency
virus
1)
9 / 12 PRO A  95
LEU A 100
VAL A 106
VAL A 179
TYR A 181
PRO A 225
TRP A 229
LEU A 234
TYR A 318
PC0  A 999 ( 4.9A)
PC0  A 999 ( 3.9A)
PC0  A 999 ( 4.8A)
PC0  A 999 (-4.4A)
PC0  A 999 (-3.9A)
None
PC0  A 999 ( 4.2A)
PC0  A 999 (-4.2A)
PC0  A 999 (-4.3A)
0.76A 6eliA-2hnzA:
36.5
6eliA-2hnzA:
100.00