SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PBZ'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1AQ7_B_AG2B4_1 (TRYPSINAERUGINOSIN 98-B) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 6 / 8 | HIS A 57ASP A 189GLN A 192SER A 195GLY A 216GLY A 226 | NonePBZ A 305 (-2.7A)PBZ A 305 (-3.2A)PBZ A 305 (-2.9A)PBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.90A | 1aq7A-1fiwA:34.4 | 1aq7A-1fiwA:34.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1AQ7_B_AG2B4_1 (TRYPSINAERUGINOSIN 98-B) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 6 / 8 | HIS A 57ASP A 189GLN A 192SER A 195GLY A 216GLY A 226 | NonePBZ A 308 (-2.9A)PBZ A 308 (-3.6A)PBZ A 308 (-3.2A)PBZ A 308 (-3.6A)PBZ A 308 ( 3.7A) | 0.68A | 1aq7A-1fizA:33.8 | 1aq7A-1fizA:37.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1BCU_H_PRLH280_0 (ALPHA-THROMBIN) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 5 / 9 | ASP A 189SER A 195TRP A 215GLY A 216GLY A 226 | PBZ A 305 (-2.7A)PBZ A 305 (-2.9A)NonePBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.38A | 1bcuH-1fiwA:35.4 | 1bcuH-1fiwA:31.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1BCU_H_PRLH280_0 (ALPHA-THROMBIN) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 5 / 9 | ASP A 189SER A 195TRP A 215GLY A 216GLY A 226 | PBZ A 308 (-2.9A)PBZ A 308 (-3.2A)NonePBZ A 308 (-3.6A)PBZ A 308 ( 3.7A) | 0.52A | 1bcuH-1fizA:17.5 | 1bcuH-1fizA:35.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DWC_H_MITH1_1 (ALPHA-THROMBIN(LARGE SUBUNIT)) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 5 / 9 | HIS A 57ASP A 189SER A 195TRP A 215GLY A 226 | NonePBZ A 305 (-2.7A)PBZ A 305 (-2.9A)NonePBZ A 305 (-3.3A) | 0.47A | 1dwcH-1fiwA:34.8 | 1dwcH-1fiwA:31.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1DWC_H_MITH1_1 (ALPHA-THROMBIN(LARGE SUBUNIT)) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 5 / 9 | HIS A 57ASP A 189SER A 195TRP A 215GLY A 226 | NonePBZ A 308 (-2.9A)PBZ A 308 (-3.2A)NonePBZ A 308 ( 3.7A) | 0.41A | 1dwcH-1fizA:34.3 | 1dwcH-1fizA:35.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETR_H_MITH1_1 (EPSILON-THROMBIN) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 6 / 12 | HIS A 57ASP A 189SER A 195TRP A 215GLY A 216GLY A 226 | NonePBZ A 305 (-2.7A)PBZ A 305 (-2.9A)NonePBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.60A | 1etrH-1fiwA:34.7 | 1etrH-1fiwA:34.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ETR_H_MITH1_1 (EPSILON-THROMBIN) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 6 / 12 | HIS A 57ASP A 189SER A 195TRP A 215GLY A 216GLY A 226 | NonePBZ A 308 (-2.9A)PBZ A 308 (-3.2A)NonePBZ A 308 (-3.6A)PBZ A 308 ( 3.7A) | 0.54A | 1etrH-1fizA:34.1 | 1etrH-1fizA:35.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1F5L_A_AMRA301_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 4 / 8 | ASP A 189SER A 195GLY A 216GLY A 226 | PBZ A 305 (-2.7A)PBZ A 305 (-2.9A)PBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.30A | 1f5lA-1fiwA:36.6 | 1f5lA-1fiwA:33.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1F5L_A_AMRA301_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 4 / 8 | ASP A 189SER A 195GLY A 216GLY A 226 | PBZ A 308 (-2.9A)PBZ A 308 (-3.2A)PBZ A 308 (-3.6A)PBZ A 308 ( 3.7A) | 0.43A | 1f5lA-1fizA:36.3 | 1f5lA-1fizA:32.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TNL_A_TPAA900_1 (TRYPSIN) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 4 / 6 | ASP A 189SER A 195GLY A 216GLY A 226 | PBZ A 305 (-2.7A)PBZ A 305 (-2.9A)PBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.35A | 1tnlA-1fiwA:16.2 | 1tnlA-1fiwA:34.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1TNL_A_TPAA900_1 (TRYPSIN) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 4 / 6 | ASP A 189SER A 195GLY A 216GLY A 226 | PBZ A 308 (-2.9A)PBZ A 308 (-3.2A)PBZ A 308 (-3.6A)PBZ A 308 ( 3.7A) | 0.32A | 1tnlA-1fizA:17.0 | 1tnlA-1fizA:37.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1X7P_B_SAMB302_0 (RRNAMETHYLTRANSFERASE) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 5 / 10 | THR A 190GLY A 140GLY A 142ILE A 188ALA A 158 | PBZ A 305 (-3.9A)NoneNoneNoneNone | 1.10A | 1x7pA-1fiwA:undetectable1x7pB-1fiwA:undetectable | 1x7pA-1fiwA:23.031x7pB-1fiwA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1X7P_B_SAMB302_0 (RRNAMETHYLTRANSFERASE) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 5 / 10 | THR A 190GLY A 140GLY A 142ILE A 188ALA A 158 | PBZ A 308 (-3.4A)NoneNoneNoneNone | 1.02A | 1x7pA-1fizA:undetectable1x7pB-1fizA:undetectable | 1x7pA-1fizA:19.471x7pB-1fizA:19.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2OTV_A_NCAA1301_0 (CATIONIC TRYPSIN) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 4 / 6 | ASP A 189SER A 195GLY A 216GLY A 226 | PBZ A 305 (-2.7A)PBZ A 305 (-2.9A)PBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.23A | 2otvA-1fiwA:16.4 | 2otvA-1fiwA:34.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2OTV_A_NCAA1301_0 (CATIONIC TRYPSIN) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 4 / 6 | ASP A 189SER A 195GLY A 216GLY A 226 | PBZ A 308 (-2.9A)PBZ A 308 (-3.2A)PBZ A 308 (-3.6A)PBZ A 308 ( 3.7A) | 0.36A | 2otvA-1fizA:17.1 | 2otvA-1fizA:37.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2P16_A_GG2A298_1 (COAGULATION FACTOR X(EC 3.4.21.6)(STUART FACTOR)(STUART-PROWERFACTOR)) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 6 / 12 | ASP A 189SER A 195TRP A 215GLY A 216GLY A 226TYR A 228 | PBZ A 305 (-2.7A)PBZ A 305 (-2.9A)NonePBZ A 305 (-3.4A)PBZ A 305 (-3.3A)None | 0.30A | 2p16A-1fiwA:35.3 | 2p16A-1fiwA:31.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2P16_A_GG2A298_1 (COAGULATION FACTOR X(EC 3.4.21.6)(STUART FACTOR)(STUART-PROWERFACTOR)) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 6 / 12 | ASP A 189SER A 195TRP A 215GLY A 216GLY A 226TYR A 228 | PBZ A 308 (-2.9A)PBZ A 308 (-3.2A)NonePBZ A 308 (-3.6A)PBZ A 308 ( 3.7A)None | 0.41A | 2p16A-1fizA:34.1 | 2p16A-1fizA:34.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VIN_A_505A1247_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR CHAIN B) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 4 / 8 | ASP A 189SER A 195GLY A 216GLY A 226 | PBZ A 305 (-2.7A)PBZ A 305 (-2.9A)PBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.34A | 2vinA-1fiwA:37.1 | 2vinA-1fiwA:33.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2VIN_A_505A1247_1 (UROKINASE-TYPEPLASMINOGENACTIVATOR CHAIN B) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 4 / 8 | ASP A 189SER A 195GLY A 216GLY A 226 | PBZ A 308 (-2.9A)PBZ A 308 (-3.2A)PBZ A 308 (-3.6A)PBZ A 308 ( 3.7A) | 0.33A | 2vinA-1fizA:14.1 | 2vinA-1fizA:32.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2W26_A_RIVA1001_1 (ACTIVATED FACTOR XAHEAVY CHAIN) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 7 / 12 | ASP A 189SER A 195TRP A 215GLY A 216GLY A 219GLY A 226TYR A 228 | PBZ A 305 (-2.7A)PBZ A 305 (-2.9A)NonePBZ A 305 (-3.4A)PBZ A 305 (-4.9A)PBZ A 305 (-3.3A)None | 0.34A | 2w26A-1fiwA:35.4 | 2w26A-1fiwA:31.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2W26_A_RIVA1001_1 (ACTIVATED FACTOR XAHEAVY CHAIN) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 7 / 12 | ASP A 189SER A 195TRP A 215GLY A 216GLY A 219GLY A 226TYR A 228 | PBZ A 308 (-2.9A)PBZ A 308 (-3.2A)NonePBZ A 308 (-3.6A)NonePBZ A 308 ( 3.7A)None | 0.50A | 2w26A-1fizA:16.2 | 2w26A-1fizA:34.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3DCM_X_SAMX5452_0 (UNCHARACTERIZEDPROTEIN TM_1570) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 5 / 11 | THR A 190GLY A 140GLY A 142ILE A 188ALA A 158 | PBZ A 308 (-3.4A)NoneNoneNoneNone | 0.97A | 3dcmX-1fizA:undetectable | 3dcmX-1fizA:21.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GY3_A_PNTA246_0 (CATIONIC TRYPSIN) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 6 / 11 | ASP A 189GLN A 192SER A 195TRP A 215GLY A 216GLY A 226 | PBZ A 305 (-2.7A)PBZ A 305 (-3.2A)PBZ A 305 (-2.9A)NonePBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.81A | 3gy3A-1fiwA:16.4 | 3gy3A-1fiwA:34.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GY3_A_PNTA246_0 (CATIONIC TRYPSIN) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 6 / 11 | HIS A 57ASP A 189SER A 195TRP A 215GLY A 216GLY A 226 | NonePBZ A 305 (-2.7A)PBZ A 305 (-2.9A)NonePBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.37A | 3gy3A-1fiwA:16.4 | 3gy3A-1fiwA:34.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GY3_A_PNTA246_0 (CATIONIC TRYPSIN) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 7 / 11 | HIS A 57ASP A 189GLN A 192SER A 195TRP A 215GLY A 216GLY A 226 | NonePBZ A 308 (-2.9A)PBZ A 308 (-3.6A)PBZ A 308 (-3.2A)NonePBZ A 308 (-3.6A)PBZ A 308 ( 3.7A) | 0.56A | 3gy3A-1fizA:16.9 | 3gy3A-1fizA:37.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3RXF_A_4APA9_1 (CATIONIC TRYPSIN) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 4 / 6 | SER A 195TRP A 215GLY A 216GLY A 226 | PBZ A 305 (-2.9A)NonePBZ A 305 (-3.4A)PBZ A 305 (-3.3A) | 0.28A | 3rxfA-1fiwA:16.9 | 3rxfA-1fiwA:34.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3RXF_A_4APA9_1 (CATIONIC TRYPSIN) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 4 / 6 | SER A 195TRP A 215GLY A 216GLY A 226 | PBZ A 308 (-3.2A)NonePBZ A 308 (-3.6A)PBZ A 308 ( 3.7A) | 0.28A | 3rxfA-1fizA:16.5 | 3rxfA-1fizA:37.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4FU8_A_ACTA302_0 (UROKINASE-TYPEPLASMINOGENACTIVATOR) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 4 / 5 | HIS A 57GLN A 192GLY A 193SER A 195 | NonePBZ A 308 (-3.6A)NonePBZ A 308 (-3.2A) | 0.87A | 4fu8A-1fizA:36.4 | 4fu8A-1fizA:32.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LRH_B_FOLB301_1 (FOLATE RECEPTORALPHA) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 3 / 3 | ASP A 102TRP A 63SER A 195 | NoneNonePBZ A 305 (-2.9A) | 1.06A | 4lrhB-1fiwA:undetectable | 4lrhB-1fiwA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4LRH_B_FOLB301_1 (FOLATE RECEPTORALPHA) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 3 / 3 | ASP A 102TRP A 63SER A 195 | NoneNonePBZ A 308 (-3.2A) | 1.07A | 4lrhB-1fizA:undetectable | 4lrhB-1fizA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RDX_A_HISA502_0 (HISTIDINE--TRNALIGASE) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 4 / 7 | THR A 190GLY A 216TYR A 228GLY A 226 | PBZ A 308 (-3.4A)PBZ A 308 (-3.6A)NonePBZ A 308 ( 3.7A) | 0.91A | 4rdxA-1fizA:undetectable | 4rdxA-1fizA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6C2M_C_SUEC1203_0 (NS3 PROTEASE) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 5 / 12 | HIS A 57ASP A 102GLY A 193SER A 195VAL A 217 | NoneNoneNonePBZ A 305 (-2.9A)None | 0.95A | 6c2mC-1fiwA:9.7 | 6c2mC-1fiwA:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6C2M_C_SUEC1203_0 (NS3 PROTEASE) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 5 / 12 | HIS A 57ASP A 102GLY A 193SER A 195VAL A 217 | NoneNoneNonePBZ A 308 (-3.2A)None | 0.88A | 6c2mC-1fizA:9.5 | 6c2mC-1fizA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HU9_H_PCFH604_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 8CYTOCHROME C OXIDASEPOLYPEPTIDE 5A,MITOCHONDRIAL) |
1fiw | BETA-ACROSIN HEAVYCHAIN (Ovisaries) | 4 / 8 | GLY A 216GLY A 193SER A 195ALA A 55 | PBZ A 305 (-3.4A)NonePBZ A 305 (-2.9A)None | 0.76A | 6hu9H-1fiwA:undetectable6hu9e-1fiwA:undetectable | 6hu9H-1fiwA:14.796hu9e-1fiwA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HU9_H_PCFH604_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 8CYTOCHROME C OXIDASEPOLYPEPTIDE 5A,MITOCHONDRIAL) |
1fiz | BETA-ACROSIN HEAVYCHAIN (Susscrofa) | 4 / 8 | GLY A 216GLY A 193SER A 195ALA A 55 | PBZ A 308 (-3.6A)NonePBZ A 308 (-3.2A)None | 0.78A | 6hu9H-1fizA:undetectable6hu9e-1fizA:undetectable | 6hu9H-1fizA:12.986hu9e-1fizA:19.77 |