SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PBM'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 5jpn COMPLEMENT C4-A
(Homo
sapiens) 		3 / 3 SER A 216
MET A 177
ASP A 221
 None
None
PBM  A 704 (-3.6A)
 0.90A 4mm4B-5jpnA:
undetectable		 4mm4B-5jpnA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 5jpn COMPLEMENT C4-A
(Homo
sapiens) 		3 / 3 TYR B 977
LEU B1362
ASP B 965
 PBM  B1515 ( 4.9A)
None
None
 0.85A 5zv2B-5jpnB:
undetectable		 5zv2B-5jpnB:
7.17