SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'PBG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_A_SAMA401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 3obk DELTA-AMINOLEVULINIC
ACID DEHYDRATASE
(Toxoplasma
gondii) 		5 / 12 ARG A 189
GLU A 107
ALA A 105
ASP A 146
PRO A 139
 MG  A 365 ( 4.7A)
None
None
PBG  A 360 (-3.4A)
None
 1.49A 4dmgA-3obkA:
undetectable		 4dmgA-3obkA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_B_SAMB401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 3obk DELTA-AMINOLEVULINIC
ACID DEHYDRATASE
(Toxoplasma
gondii) 		5 / 11 ARG A 189
GLU A 107
ALA A 105
ASP A 146
PRO A 139
 MG  A 365 ( 4.7A)
None
None
PBG  A 360 (-3.4A)
None
 1.42A 4dmgB-3obkA:
0.0		 4dmgB-3obkA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3obk DELTA-AMINOLEVULINIC
ACID DEHYDRATASE
(Toxoplasma
gondii) 		3 / 3 LYS A 213
LEU A 208
ASP A 134
 PBG  A 360 (-2.8A)
None
PBG  A 360 (-3.8A)
 0.92A 5zv2A-3obkA:
undetectable		 5zv2A-3obkA:
13.75