SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'P6C'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4
(Viscum
album) 		4 / 8 GLY A 108
ILE A 154
SER A 158
GLU A 159
 None
None
None
P6C  A1001 ( 4.4A)
 0.56A 1mrjA-1yf8A:
31.4		 1mrjA-1yf8A:
35.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4
(Viscum
album) 		4 / 8 ILE A 154
SER A 158
GLU A 159
ARG A 162
 None
None
P6C  A1001 ( 4.4A)
P6C  A1001 (-2.6A)
 0.48A 1mrjA-1yf8A:
31.4		 1mrjA-1yf8A:
35.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4
(Viscum
album) 		4 / 8 TYR A  75
ILE A 154
SER A 158
GLU A 159
 P6C  A1001 (-4.6A)
None
None
P6C  A1001 ( 4.4A)
 0.88A 1mrjA-1yf8A:
31.4		 1mrjA-1yf8A:
35.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4
(Viscum
album) 		5 / 9 TYR A  75
GLY A 108
ILE A 154
GLU A 159
ARG A 162
 P6C  A1001 (-4.6A)
None
None
P6C  A1001 ( 4.4A)
P6C  A1001 (-2.6A)
 0.95A 4yp2B-1yf8A:
31.7		 4yp2B-1yf8A:
34.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4
(Viscum
album) 		5 / 9 TYR A  75
GLY A 108
ILE A 154
GLU A 159
ARG A 162
 P6C  A1001 (-4.6A)
None
None
P6C  A1001 ( 4.4A)
P6C  A1001 (-2.6A)
 0.94A 5cf9B-1yf8A:
31.8		 5cf9B-1yf8A:
34.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4
(Viscum
album) 		4 / 6 SER A 109
ARG A 120
GLU A 114
TYR A 110
 P6C  A1001 (-3.5A)
None
None
None
 1.48A 5x7pA-1yf8A:
undetectable		 5x7pA-1yf8A:
11.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 1yf8 BETA-GALACTOSIDE-SPE
CIFIC LECTIN 4
(Viscum
album) 		5 / 6 TYR A  75
VAL A  76
ILE A 154
GLU A 159
ARG A 162
 P6C  A1001 (-4.6A)
None
None
P6C  A1001 ( 4.4A)
P6C  A1001 (-2.6A)
 0.64A 5z3jA-1yf8A:
33.8		 5z3jA-1yf8A:
39.85