SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'P33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A4L_B_DCFB853_1 (ADENOSINE DEAMINASE)	1zzm	PUTATIVE DEOXYRIBONUCLEASE YJJV (Escherichia coli)	5 / 12	HIS A 11 MET A 69 HIS A 157 ASP A 207 ASP A 210	ZN A 401 (-3.2A) P33 A 501 (-3.7A) ZN A 402 (-3.3A) ZN A 401 (-3.2A) P33 A 501 (-3.7A)	1.39A	1a4lB-1zzmA: 14.1	1a4lB-1zzmA: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E9Y_B_HAEB800_1 (UREASE SUBUNIT BETA)	1zzm	PUTATIVE DEOXYRIBONUCLEASE YJJV (Escherichia coli)	4 / 5	HIS A 9 HIS A 66 HIS A 133 ASP A 207	ZN A 401 (-3.3A) P33 A 501 (-4.0A) ZN A 402 (-3.1A) ZN A 401 (-3.2A)	0.79A	1e9yB-1zzmA: 14.5	1e9yB-1zzmA: 17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EII_A_RTLA135_0 (CELLULAR RETINOL-BINDING PROTEIN II)	5xaw	SODIUM CHANNEL SUBUNIT BETA-4 (Homo sapiens)	5 / 12	ALA A 75 PHE A 76 LEU A 121 LEU A 79 ARG A 100	PG4 A 202 ( 4.5A) P33 A 201 ( 4.9A) None None PG4 A 202 (-4.0A)	1.38A	1eiiA-5xawA: undetectable	1eiiA-5xawA: 26.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1F86_B_T44B528_1 (TRANSTHYRETIN THR119MET VARIANT)	2i02	GENERAL STRESS PROTEIN OF COG3871 (Nostoc punctiforme)	4 / 4	LYS A 95 LEU A 93 ALA A 122 LEU A 124	P33 A 201 (-3.3A) None P33 A 201 ( 3.9A) None	1.03A	1f86B-2i02A: undetectable	1f86B-2i02A: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FWE_C_HAEC989_1 (UREASE)	1zzm	PUTATIVE DEOXYRIBONUCLEASE YJJV (Escherichia coli)	5 / 6	HIS A 9 HIS A 11 HIS A 66 HIS A 133 ASP A 207	ZN A 401 (-3.3A) ZN A 401 (-3.2A) P33 A 501 (-4.0A) ZN A 402 (-3.1A) ZN A 401 (-3.2A)	0.82A	1fweC-1zzmA: 14.1	1fweC-1zzmA: 19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ITU_A_CILA451_1 (RENAL DIPEPTIDASE)	1zzm	PUTATIVE DEOXYRIBONUCLEASE YJJV (Escherichia coli)	5 / 12	GLU A 97 HIS A 66 HIS A 133 HIS A 157 ASP A 207	ZN A 401 ( 2.3A) P33 A 501 (-4.0A) ZN A 402 (-3.1A) ZN A 402 (-3.3A) ZN A 401 (-3.2A)	0.99A	1ituA-1zzmA: 14.6	1ituA-1zzmA: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ITU_B_CILB452_1 (RENAL DIPEPTIDASE)	1zzm	PUTATIVE DEOXYRIBONUCLEASE YJJV (Escherichia coli)	5 / 12	GLU A 97 HIS A 66 HIS A 133 HIS A 157 ASP A 207	ZN A 401 ( 2.3A) P33 A 501 (-4.0A) ZN A 402 (-3.1A) ZN A 402 (-3.3A) ZN A 401 (-3.2A)	1.00A	1ituB-1zzmA: 2.0	1ituB-1zzmA: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KXH_A_ACRA598_2 (ALPHA-AMYLASE)	4xwl	EXOGLUCANASE S (Clostridium cellulovorans)	3 / 3	TRP A 354 TYR A 385 LEU A 287	None P33 A 705 (-3.9A) None	0.83A	1kxhA-4xwlA: undetectable	1kxhA-4xwlA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_G_NCTG1206_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	5l2v	CHITIN-BINDING PROTEIN (Listeria monocytogenes)	4 / 8	TRP A 79 TYR A 3 TRP A 147 LEU A 126	None P33 A 202 (-4.8A) None None	1.49A	1uw6G-5l2vA: undetectable 1uw6H-5l2vA: undetectable	1uw6G-5l2vA: 21.23 1uw6H-5l2vA: 21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XVA_B_ACTB294_0 (GLYCINE N-METHYLTRANSFERASE)	5l2v	CHITIN-BINDING PROTEIN (Listeria monocytogenes)	4 / 6	ALA A 127 TYR A 3 ILE A 4 LEU A 81	None P33 A 202 (-4.8A) None None	0.96A	1xvaA-5l2vA: undetectable 1xvaB-5l2vA: undetectable	1xvaA-5l2vA: 20.13 1xvaB-5l2vA: 20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GL0_B_ADNB902_1 (CONSERVED HYPOTHETICAL PROTEIN)	4w8o	LUCIFERASE-LIKE ENZYMEAMP-COA-LIGASE (Zophobas atratus)	5 / 11	ASN A 99 ILE A 228 THR A 224 ASN A 79 VAL A 206	None P33 A 501 ( 4.3A) None None None	1.34A	2gl0B-4w8oA: undetectable 2gl0C-4w8oA: undetectable	2gl0B-4w8oA: 14.88 2gl0C-4w8oA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2GL0_E_ADNE905_1 (CONSERVED HYPOTHETICAL PROTEIN)	4w8o	LUCIFERASE-LIKE ENZYMEAMP-COA-LIGASE (Zophobas atratus)	5 / 11	ASN A 99 ILE A 228 THR A 224 ASN A 79 VAL A 206	None P33 A 501 ( 4.3A) None None None	1.26A	2gl0E-4w8oA: undetectable 2gl0F-4w8oA: undetectable	2gl0E-4w8oA: 14.88 2gl0F-4w8oA: 14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYR_B_SVRB401_4 (NAD-DEPENDENT DEACETYLASE SIRTUIN-5)	3cmb	ACETOACETATE DECARBOXYLASE (Methanoculleus marisnigri)	4 / 5	ALA A 99 ALA A 63 ALA A 33 GLN A 201	None None None P33 A 269 (-3.4A)	0.88A	2nyrB-3cmbA: undetectable	2nyrB-3cmbA: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OA1_B_ADNB2005_1 (TRYPTOPHAN HALOGENASE)	4z5q	CYTOCHROME P450 HYDROXYLASE (Streptomyces atroolivaceus)	4 / 7	GLY A 241 GLY A 240 VAL A 152 LEU A 357	HEM A 401 (-3.2A) P33 A 407 ( 3.4A) None HEM A 401 (-4.6A)	0.78A	2oa1B-4z5qA: undetectable	2oa1B-4z5qA: 22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QMM_A_SAMA301_0 (UPF0217 PROTEIN AF_1056)	5l2v	CHITIN-BINDING PROTEIN (Listeria monocytogenes)	5 / 9	LEU A 13 ILE A 18 GLY A 17 SER A 9 SER A 5	None None P33 A 202 ( 3.7A) None None	1.09A	2qmmA-5l2vA: undetectable	2qmmA-5l2vA: 23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8I_A_RO7A1_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	3cc1	PUTATIVE ALPHA-N-ACETYLGALACT OSAMINIDASE (Bacillus halodurans)	5 / 12	CYH A 310 SER A 343 MET A 13 ILE A 336 VAL A 399	None None None None P33 A 439 ( 4.0A)	1.40A	3g8iA-3cc1A: undetectable	3g8iA-3cc1A: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OWX_B_XRAB233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4z5q	CYTOCHROME P450 HYDROXYLASE (Streptomyces atroolivaceus)	5 / 11	VAL A 360 PHE A 345 GLY A 241 GLY A 240 ILE A 237	None HEM A 401 (-4.6A) HEM A 401 (-3.2A) P33 A 407 ( 3.4A) HEM A 401 (-4.5A)	0.90A	3owxA-4z5qA: undetectable 3owxB-4z5qA: undetectable	3owxA-4z5qA: 21.21 3owxB-4z5qA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UA1_A_08YA600_1 (CYTOCHROME P450 3A4)	3ffr	PHOSPHOSERINE AMINOTRANSFERASE SERC (Cytophaga hutchinsonii)	5 / 12	ILE A 316 PHE A 287 ALA A 323 THR A 8 ALA A 326	P33 A 368 ( 4.6A) None None None None	0.91A	3ua1A-3ffrA: undetectable	3ua1A-3ffrA: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C5N_C_PXLC300_1 (PHOSPHOMETHYLPYRIMID INE KINASE)	4w8o	LUCIFERASE-LIKE ENZYMEAMP-COA-LIGASE (Zophobas atratus)	4 / 8	GLY A 323 GLY A 328 VAL A 379 HIS A 197	P33 A 501 ( 4.2A) P33 A 501 ( 4.0A) None None	0.86A	4c5nC-4w8oA: undetectable	4c5nC-4w8oA: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FFW_B_715B801_2 (DIPEPTIDYL PEPTIDASE 4)	4xwl	EXOGLUCANASE S (Clostridium cellulovorans)	3 / 3	ARG A 260 TYR A 385 ASN A 311	None P33 A 705 (-3.9A) None	0.78A	4ffwB-4xwlA: undetectable	4ffwB-4xwlA: 20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4z5q	CYTOCHROME P450 HYDROXYLASE (Streptomyces atroolivaceus)	5 / 12	GLY A 241 GLY A 240 ILE A 237 VAL A 360 PHE A 345	HEM A 401 (-3.2A) P33 A 407 ( 3.4A) HEM A 401 (-4.5A) None HEM A 401 (-4.6A)	0.95A	4fglA-4z5qA: undetectable 4fglB-4z5qA: undetectable	4fglA-4z5qA: 21.21 4fglB-4z5qA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4H9M_A_HAEA929_1 (UREASE)	1zzm	PUTATIVE DEOXYRIBONUCLEASE YJJV (Escherichia coli)	4 / 5	HIS A 9 HIS A 66 HIS A 133 ASP A 207	ZN A 401 (-3.3A) P33 A 501 (-4.0A) ZN A 402 (-3.1A) ZN A 401 (-3.2A)	0.71A	4h9mA-1zzmA: 13.3	4h9mA-1zzmA: 13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYK_B_IMNB300_1 (LACTOYLGLUTATHIONE LYASE)	4xvx	ACYL-[ACYL-CARRIER-P ROTEIN] DEHYDROGENASE MBTN (Mycobacterium tuberculosis)	5 / 12	ALA A 77 LEU A 39 PHE A 49 GLY A 243 LEU A 67	P33 A 401 ( 3.7A) None None None None	1.17A	4kykA-4xvxA: undetectable 4kykB-4xvxA: undetectable	4kykA-4xvxA: 16.92 4kykB-4xvxA: 16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R21_A_STRA601_1 (CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2)	4xvx	ACYL-[ACYL-CARRIER-P ROTEIN] DEHYDROGENASE MBTN (Mycobacterium tuberculosis)	4 / 6	ALA A 316 GLY A 355 ILE A 245 VAL A 81	None P33 A 401 (-3.4A) None P33 A 401 (-4.5A)	0.77A	4r21A-4xvxA: undetectable	4r21A-4xvxA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBP_C_HAEC800_1 (PROTEIN (UREASE (CHAIN C)))	1zzm	PUTATIVE DEOXYRIBONUCLEASE YJJV (Escherichia coli)	5 / 6	HIS A 9 HIS A 11 HIS A 66 HIS A 133 ASP A 207	ZN A 401 (-3.3A) ZN A 401 (-3.2A) P33 A 501 (-4.0A) ZN A 402 (-3.1A) ZN A 401 (-3.2A)	0.70A	4ubpC-1zzmA: 14.2	4ubpC-1zzmA: 17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZVM_B_DM2B303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	4z5q	CYTOCHROME P450 HYDROXYLASE (Streptomyces atroolivaceus)	5 / 11	VAL A 360 PHE A 345 GLY A 241 GLY A 240 ILE A 237	None HEM A 401 (-4.6A) HEM A 401 (-3.2A) P33 A 407 ( 3.4A) HEM A 401 (-4.5A)	0.90A	4zvmA-4z5qA: undetectable 4zvmB-4z5qA: undetectable	4zvmA-4z5qA: 21.03 4zvmB-4z5qA: 21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESH_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	4z5q	CYTOCHROME P450 HYDROXYLASE (Streptomyces atroolivaceus)	5 / 12	ALA A 276 LEU A 280 ILE A 239 LEU A 357 PHE A 345	None None P33 A 407 ( 4.5A) HEM A 401 (-4.6A) HEM A 401 (-4.6A)	1.15A	5eshA-4z5qA: 25.2	5eshA-4z5qA: 22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JS5_A_ASCA202_0 (CYTOCHROME C')	6aom	ENDOPLASMIN (Canis lupus)	3 / 3	CYH A 138 LYS A 137 HIS A 146	None P33 A 402 (-2.6A) P33 A 402 ( 4.0A)	1.18A	5js5A-6aomA: undetectable	5js5A-6aomA: 16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5O4Y_D_CCSD14_0 (PHE-MAA-ASN-PRO-HIS- LEU-SER-TRP-SER-TRP- 9KK-9KK-ARG-CCS-GLY- NH2 PROGRAMMED CELL DEATH 1 LIGAND 1)	4xvx	ACYL-[ACYL-CARRIER-P ROTEIN] DEHYDROGENASE MBTN (Mycobacterium tuberculosis)	5 / 12	LEU A 351 SER A 76 GLY A 78 GLY A 201 ARG A 347	P33 A 401 ( 4.0A) None None None None	1.21A	5o4yD-4xvxA: undetectable 5o4yE-4xvxA: undetectable	5o4yD-4xvxA: 3.54 5o4yE-4xvxA: 14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OEX_A_CUA604_0 (THIOCYANATE DEHYDROGENASE)	1zzm	PUTATIVE DEOXYRIBONUCLEASE YJJV (Escherichia coli)	3 / 3	HIS A 11 HIS A 66 HIS A 133	ZN A 401 (-3.2A) P33 A 501 (-4.0A) ZN A 402 (-3.1A)	0.95A	5oexA-1zzmA: undetectable	5oexA-1zzmA: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCG_A_08YA602_1 (CYTOCHROME P450 3A4)	3ffr	PHOSPHOSERINE AMINOTRANSFERASE SERC (Cytophaga hutchinsonii)	5 / 12	ILE A 316 PHE A 287 ALA A 323 THR A 8 ALA A 326	P33 A 368 ( 4.6A) None None None None	0.92A	5vcgA-3ffrA: undetectable	5vcgA-3ffrA: 23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X80_A_SALA201_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	3cmb	ACETOACETATE DECARBOXYLASE (Methanoculleus marisnigri)	4 / 5	VAL A 197 PRO A 200 GLY A 259 TYR A 199	None None None P33 A 269 (-3.8A)	1.34A	5x80A-3cmbA: undetectable 5x80B-3cmbA: undetectable	5x80A-3cmbA: 23.05 5x80B-3cmbA: 23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X80_D_SALD201_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	3cmb	ACETOACETATE DECARBOXYLASE (Methanoculleus marisnigri)	4 / 5	PRO A 200 GLY A 259 TYR A 199 VAL A 197	None None P33 A 269 (-3.8A) None	1.35A	5x80C-3cmbA: undetectable 5x80D-3cmbA: undetectable	5x80C-3cmbA: 23.05 5x80D-3cmbA: 23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BRD_B_RFPB502_1 (RIFAMPIN MONOOXYGENASE)	3cmb	ACETOACETATE DECARBOXYLASE (Methanoculleus marisnigri)	5 / 12	GLY A 114 THR A 9 GLY A 19 GLY A 18 MET A 258	P33 A 269 ( 4.5A) None None None None	1.02A	6brdB-3cmbA: undetectable	6brdB-3cmbA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DCH_A_ACTA401_0 (SCOE PROTEIN)	1zzm	PUTATIVE DEOXYRIBONUCLEASE YJJV (Escherichia coli)	4 / 5	THR A 41 HIS A 9 ASP A 207 HIS A 157	P33 A 501 ( 4.6A) ZN A 401 (-3.3A) ZN A 401 (-3.2A) ZN A 402 (-3.3A)	0.88A	6dchA-1zzmA: undetectable	6dchA-1zzmA: 24.40

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A4L_B_DCFB853_1","ADENOSINE DEAMINASE","1zzm","PUTATIVE DEOXYRIBONUCLEASE YJJV","Escherichia coli",5,"HIS A  11;MET A  69;HIS A 157;ASP A 207;ASP A 210"," ZN A 401 (-3.2A);P33 A 501 (-3.7A); ZN A 402 (-3.3A); ZN A 401 (-3.2A);P33 A 501 (-3.7A)","1.39A","1a4lB-1zzmA:14.1",null],["1E9Y_B_HAEB800_1","UREASE SUBUNIT BETA","1zzm","PUTATIVE DEOXYRIBONUCLEASE YJJV","Escherichia coli",4,"HIS A   9;HIS A  66;HIS A 133;ASP A 207"," ZN A 401 (-3.3A);P33 A 501 (-4.0A); ZN A 402 (-3.1A); ZN A 401 (-3.2A)","0.79A","1e9yB-1zzmA:14.5","1a4lB-1zzmA:22.34"],["1EII_A_RTLA135_0","CELLULAR RETINOL-BINDING PROTEIN II","5xaw","SODIUM CHANNEL SUBUNIT BETA-4","Homo sapiens",5,"ALA A  75;PHE A  76;LEU A 121;LEU A  79;ARG A 100","PG4 A 202 ( 4.5A);P33 A 201 ( 4.9A);None;None;PG4 A 202 (-4.0A)","1.38A","1eiiA-5xawA:undetectable","1e9yB-1zzmA:17.21"],["1F86_B_T44B528_1","TRANSTHYRETIN THR119MET VARIANT","2i02","GENERAL STRESS PROTEIN OF COG3871","Nostoc punctiforme",4,"LYS A  95;LEU A  93;ALA A 122;LEU A 124","P33 A 201 (-3.3A);None;P33 A 201 ( 3.9A);None","1.03A","1f86B-2i02A:undetectable","1eiiA-5xawA:26.43"],["1FWE_C_HAEC989_1","UREASE","1zzm","PUTATIVE DEOXYRIBONUCLEASE YJJV","Escherichia coli",5,"HIS A   9;HIS A  11;HIS A  66;HIS A 133;ASP A 207"," ZN A 401 (-3.3A); ZN A 401 (-3.2A);P33 A 501 (-4.0A); ZN A 402 (-3.1A); ZN A 401 (-3.2A)","0.82A","1fweC-1zzmA:14.1","1f86B-2i02A:21.05"],["1ITU_A_CILA451_1","RENAL DIPEPTIDASE","1zzm","PUTATIVE DEOXYRIBONUCLEASE YJJV","Escherichia coli",5,"GLU A  97;HIS A  66;HIS A 133;HIS A 157;ASP A 207"," ZN A 401 ( 2.3A);P33 A 501 (-4.0A); ZN A 402 (-3.1A); ZN A 402 (-3.3A); ZN A 401 (-3.2A)","0.99A","1ituA-1zzmA:14.6","1fweC-1zzmA:19.58"],["1ITU_B_CILB452_1","RENAL DIPEPTIDASE","1zzm","PUTATIVE DEOXYRIBONUCLEASE YJJV","Escherichia coli",5,"GLU A  97;HIS A  66;HIS A 133;HIS A 157;ASP A 207"," ZN A 401 ( 2.3A);P33 A 501 (-4.0A); ZN A 402 (-3.1A); ZN A 402 (-3.3A); ZN A 401 (-3.2A)","1.00A","1ituB-1zzmA:2.0","1ituA-1zzmA:22.03"],["1KXH_A_ACRA598_2","ALPHA-AMYLASE","4xwl","EXOGLUCANASE S","Clostridium cellulovorans",3,"TRP A 354;TYR A 385;LEU A 287","None;P33 A 705 (-3.9A);None","0.83A","1kxhA-4xwlA:undetectable","1ituB-1zzmA:22.03"],["1UW6_G_NCTG1206_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","5l2v","CHITIN-BINDING PROTEIN","Listeria monocytogenes",4,"TRP A  79;TYR A   3;TRP A 147;LEU A 126","None;P33 A 202 (-4.8A);None;None","1.49A","1uw6G-5l2vA:undetectable;1uw6H-5l2vA:undetectable","1kxhA-4xwlA:20.83"],["1XVA_B_ACTB294_0","GLYCINE N-METHYLTRANSFERASE","5l2v","CHITIN-BINDING PROTEIN","Listeria monocytogenes",4,"ALA A 127;TYR A   3;ILE A   4;LEU A  81","None;P33 A 202 (-4.8A);None;None","0.96A","1xvaA-5l2vA:undetectable;1xvaB-5l2vA:undetectable","1uw6G-5l2vA:21.23;1uw6H-5l2vA:21.23"],["2GL0_B_ADNB902_1","CONSERVED HYPOTHETICAL PROTEIN;CONSERVED HYPOTHETICAL PROTEIN","4w8o","LUCIFERASE-LIKE ENZYMEAMP-COA-LIGASE","Zophobas atratus",5,"ASN A  99;ILE A 228;THR A 224;ASN A  79;VAL A 206","None;P33 A 501 ( 4.3A);None;None;None","1.34A","2gl0B-4w8oA:undetectable;2gl0C-4w8oA:undetectable","1xvaA-5l2vA:20.13;1xvaB-5l2vA:20.13"],["2GL0_E_ADNE905_1","CONSERVED HYPOTHETICAL PROTEIN;CONSERVED HYPOTHETICAL PROTEIN","4w8o","LUCIFERASE-LIKE ENZYMEAMP-COA-LIGASE","Zophobas atratus",5,"ASN A  99;ILE A 228;THR A 224;ASN A  79;VAL A 206","None;P33 A 501 ( 4.3A);None;None;None","1.26A","2gl0E-4w8oA:undetectable;2gl0F-4w8oA:undetectable","2gl0B-4w8oA:14.88;2gl0C-4w8oA:14.88"],["2NYR_B_SVRB401_4","NAD-DEPENDENT DEACETYLASE SIRTUIN-5","3cmb","ACETOACETATE DECARBOXYLASE","Methanoculleus marisnigri",4,"ALA A  99;ALA A  63;ALA A  33;GLN A 201","None;None;None;P33 A 269 (-3.4A)","0.88A","2nyrB-3cmbA:undetectable","2gl0E-4w8oA:14.88;2gl0F-4w8oA:14.88"],["2OA1_B_ADNB2005_1","TRYPTOPHAN HALOGENASE","4z5q","CYTOCHROME P450 HYDROXYLASE","Streptomyces atroolivaceus",4,"GLY A 241;GLY A 240;VAL A 152;LEU A 357","HEM A 401 (-3.2A);P33 A 407 ( 3.4A);None;HEM A 401 (-4.6A)","0.78A","2oa1B-4z5qA:undetectable","2nyrB-3cmbA:21.70"],["2QMM_A_SAMA301_0","UPF0217 PROTEIN AF_1056","5l2v","CHITIN-BINDING PROTEIN","Listeria monocytogenes",5,"LEU A  13;ILE A  18;GLY A  17;SER A   9;SER A   5","None;None;P33 A 202 ( 3.7A);None;None","1.09A","2qmmA-5l2vA:undetectable","2oa1B-4z5qA:22.64"],["3G8I_A_RO7A1_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA","3cc1","PUTATIVE ALPHA-N-ACETYLGALACTOSAMINIDASE","Bacillus halodurans",5,"CYH A 310;SER A 343;MET A  13;ILE A 336;VAL A 399","None;None;None;None;P33 A 439 ( 4.0A)","1.40A","3g8iA-3cc1A:undetectable","2qmmA-5l2vA:23.19"],["3OWX_B_XRAB233_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","4z5q","CYTOCHROME P450 HYDROXYLASE","Streptomyces atroolivaceus",5,"VAL A 360;PHE A 345;GLY A 241;GLY A 240;ILE A 237","None;HEM A 401 (-4.6A);HEM A 401 (-3.2A);P33 A 407 ( 3.4A);HEM A 401 (-4.5A)","0.90A","3owxA-4z5qA:undetectable;3owxB-4z5qA:undetectable","3g8iA-3cc1A:21.30"],["3UA1_A_08YA600_1","CYTOCHROME P450 3A4","3ffr","PHOSPHOSERINE AMINOTRANSFERASE SERC","Cytophaga hutchinsonii",5,"ILE A 316;PHE A 287;ALA A 323;THR A   8;ALA A 326","P33 A 368 ( 4.6A);None;None;None;None","0.91A","3ua1A-3ffrA:undetectable","3owxA-4z5qA:21.21;3owxB-4z5qA:21.21"],["4C5N_C_PXLC300_1","PHOSPHOMETHYLPYRIMIDINE KINASE","4w8o","LUCIFERASE-LIKE ENZYMEAMP-COA-LIGASE","Zophobas atratus",4,"GLY A 323;GLY A 328;VAL A 379;HIS A 197","P33 A 501 ( 4.2A);P33 A 501 ( 4.0A);None;None","0.86A","4c5nC-4w8oA:undetectable","3ua1A-3ffrA:22.47"],["4FFW_B_715B801_2","DIPEPTIDYL PEPTIDASE 4","4xwl","EXOGLUCANASE S","Clostridium cellulovorans",3,"ARG A 260;TYR A 385;ASN A 311","None;P33 A 705 (-3.9A);None","0.78A","4ffwB-4xwlA:undetectable","4c5nC-4w8oA:21.88"],["4FGL_A_CLQA303_0","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","4z5q","CYTOCHROME P450 HYDROXYLASE","Streptomyces atroolivaceus",5,"GLY A 241;GLY A 240;ILE A 237;VAL A 360;PHE A 345","HEM A 401 (-3.2A);P33 A 407 ( 3.4A);HEM A 401 (-4.5A);None;HEM A 401 (-4.6A)","0.95A","4fglA-4z5qA:undetectable;4fglB-4z5qA:undetectable","4ffwB-4xwlA:20.77"],["4H9M_A_HAEA929_1","UREASE","1zzm","PUTATIVE DEOXYRIBONUCLEASE YJJV","Escherichia coli",4,"HIS A   9;HIS A  66;HIS A 133;ASP A 207"," ZN A 401 (-3.3A);P33 A 501 (-4.0A); ZN A 402 (-3.1A); ZN A 401 (-3.2A)","0.71A","4h9mA-1zzmA:13.3","4fglA-4z5qA:21.21;4fglB-4z5qA:21.21"],["4KYK_B_IMNB300_1","LACTOYLGLUTATHIONE LYASE;LACTOYLGLUTATHIONE LYASE","4xvx","ACYL-[ACYL-CARRIER-PROTEIN] DEHYDROGENASE MBTN","Mycobacterium tuberculosis",5,"ALA A  77;LEU A  39;PHE A  49;GLY A 243;LEU A  67","P33 A 401 ( 3.7A);None;None;None;None","1.17A","4kykA-4xvxA:undetectable;4kykB-4xvxA:undetectable","4h9mA-1zzmA:13.69"],["4R21_A_STRA601_1","CYTOCHROME P450 FAMILY 17 POLYPEPTIDE 2","4xvx","ACYL-[ACYL-CARRIER-PROTEIN] DEHYDROGENASE MBTN","Mycobacterium tuberculosis",4,"ALA A 316;GLY A 355;ILE A 245;VAL A  81","None;P33 A 401 (-3.4A);None;P33 A 401 (-4.5A)","0.77A","4r21A-4xvxA:undetectable","4kykA-4xvxA:16.92;4kykB-4xvxA:16.92"],["4UBP_C_HAEC800_1","PROTEIN (UREASE (CHAIN C))","1zzm","PUTATIVE DEOXYRIBONUCLEASE YJJV","Escherichia coli",5,"HIS A   9;HIS A  11;HIS A  66;HIS A 133;ASP A 207"," ZN A 401 (-3.3A); ZN A 401 (-3.2A);P33 A 501 (-4.0A); ZN A 402 (-3.1A); ZN A 401 (-3.2A)","0.70A","4ubpC-1zzmA:14.2","4r21A-4xvxA:21.39"],["4ZVM_B_DM2B303_1","RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE];RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE [QUINONE]","4z5q","CYTOCHROME P450 HYDROXYLASE","Streptomyces atroolivaceus",5,"VAL A 360;PHE A 345;GLY A 241;GLY A 240;ILE A 237","None;HEM A 401 (-4.6A);HEM A 401 (-3.2A);P33 A 407 ( 3.4A);HEM A 401 (-4.5A)","0.90A","4zvmA-4z5qA:undetectable;4zvmB-4z5qA:undetectable","4ubpC-1zzmA:17.98"],["5ESH_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","4z5q","CYTOCHROME P450 HYDROXYLASE","Streptomyces atroolivaceus",5,"ALA A 276;LEU A 280;ILE A 239;LEU A 357;PHE A 345","None;None;P33 A 407 ( 4.5A);HEM A 401 (-4.6A);HEM A 401 (-4.6A)","1.15A","5eshA-4z5qA:25.2","4zvmA-4z5qA:21.03;4zvmB-4z5qA:21.03"],["5JS5_A_ASCA202_0","CYTOCHROME C'","6aom","ENDOPLASMIN","Canis lupus",3,"CYH A 138;LYS A 137;HIS A 146","None;P33 A 402 (-2.6A);P33 A 402 ( 4.0A)","1.18A","5js5A-6aomA:undetectable","5eshA-4z5qA:22.18"],["5O4Y_D_CCSD14_0","PHE-MAA-ASN-PRO-HIS-LEU-SER-TRP-SER-TRP-9KK-9KK-ARG-CCS-GLY-NH2;PROGRAMMED CELL DEATH 1 LIGAND 1","4xvx","ACYL-[ACYL-CARRIER-PROTEIN] DEHYDROGENASE MBTN","Mycobacterium tuberculosis",5,"LEU A 351;SER A  76;GLY A  78;GLY A 201;ARG A 347","P33 A 401 ( 4.0A);None;None;None;None","1.21A","5o4yD-4xvxA:undetectable;5o4yE-4xvxA:undetectable","5js5A-6aomA:16.59"],["5OEX_A_CUA604_0","THIOCYANATE DEHYDROGENASE","1zzm","PUTATIVE DEOXYRIBONUCLEASE YJJV","Escherichia coli",3,"HIS A  11;HIS A  66;HIS A 133"," ZN A 401 (-3.2A);P33 A 501 (-4.0A); ZN A 402 (-3.1A)","0.95A","5oexA-1zzmA:undetectable","5o4yD-4xvxA:3.54;5o4yE-4xvxA:14.91"],["5VCG_A_08YA602_1","CYTOCHROME P450 3A4","3ffr","PHOSPHOSERINE AMINOTRANSFERASE SERC","Cytophaga hutchinsonii",5,"ILE A 316;PHE A 287;ALA A 323;THR A   8;ALA A 326","P33 A 368 ( 4.6A);None;None;None;None","0.92A","5vcgA-3ffrA:undetectable","5oexA-1zzmA:20.95"],["5X80_A_SALA201_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887;UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887","3cmb","ACETOACETATE DECARBOXYLASE","Methanoculleus marisnigri",4,"VAL A 197;PRO A 200;GLY A 259;TYR A 199","None;None;None;P33 A 269 (-3.8A)","1.34A","5x80A-3cmbA:undetectable;5x80B-3cmbA:undetectable","5vcgA-3ffrA:23.09"],["5X80_D_SALD201_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887;UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887","3cmb","ACETOACETATE DECARBOXYLASE","Methanoculleus marisnigri",4,"PRO A 200;GLY A 259;TYR A 199;VAL A 197","None;None;P33 A 269 (-3.8A);None","1.35A","5x80C-3cmbA:undetectable;5x80D-3cmbA:undetectable","5x80A-3cmbA:23.05;5x80B-3cmbA:23.05"],["6BRD_B_RFPB502_1","RIFAMPIN MONOOXYGENASE","3cmb","ACETOACETATE DECARBOXYLASE","Methanoculleus marisnigri",5,"GLY A 114;THR A   9;GLY A  19;GLY A  18;MET A 258","P33 A 269 ( 4.5A);None;None;None;None","1.02A","6brdB-3cmbA:undetectable","5x80C-3cmbA:23.05;5x80D-3cmbA:23.05"],["6DCH_A_ACTA401_0","SCOE PROTEIN","1zzm","PUTATIVE DEOXYRIBONUCLEASE YJJV","Escherichia coli",4,"THR A  41;HIS A   9;ASP A 207;HIS A 157","P33 A 501 ( 4.6A); ZN A 401 (-3.3A); ZN A 401 (-3.2A); ZN A 402 (-3.3A)","0.88A","6dchA-1zzmA:undetectable","6brdB-3cmbA:16.43"]]