SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'P16'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IEP_A_STIA201_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267TYR A 272VAL A 275ALA A 288GLU A 305MET A 309THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.83A | 1iepA-1opkA:34.6 | 1iepA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IEP_A_STIA201_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.70A | 1iepA-1opkA:34.6 | 1iepA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IEP_A_STIA201_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.60A | 1iepA-1opkA:34.6 | 1iepA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IEP_A_STIA201_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | VAL A 308VAL A 318ILE A 332MET A 337 | NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 0.50A | 1iepA-1opkA:34.6 | 1iepA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IEP_B_STIB202_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267TYR A 272VAL A 275ALA A 288GLU A 305MET A 309THR A 334GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A) | 0.77A | 1iepB-1opkA:34.7 | 1iepB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IEP_B_STIB202_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336GLY A 340ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-3.5A) | 0.78A | 1iepB-1opkA:34.7 | 1iepB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IEP_B_STIB202_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 7 | LYS A 290VAL A 308VAL A 318ILE A 332MET A 337LEU A 389 | P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)NoneP16 A 2 (-4.4A) | 0.65A | 1iepB-1opkA:34.7 | 1iepB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1IEP_B_STIB202_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 7 | VAL A 318ILE A 332MET A 337ARG A 381 | P16 A 2 ( 4.7A)P16 A 2 (-4.1A)NoneNone | 0.94A | 1iepB-1opkA:34.7 | 1iepB-1opkA:58.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1JLF_A_NVPA999_1 (HIV-1 RT A-CHAINHIV-1 RT B-CHAIN) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 8 | LEU A 346VAL A 390CYH A 388GLY A 340 | NoneNoneNoneP16 A 2 (-3.4A) | 1.05A | 1jlfA-1opkA:2.21jlfB-1opkA:1.9 | 1jlfA-1opkA:21.601jlfB-1opkA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1M17_A_AQ4A999_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305THR A 334MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.70A | 1m17A-1opkA:31.9 | 1m17A-1opkA:25.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ONI_A_BEZA502_0 (14.5 KDATRANSLATIONALINHIBITOR PROTEIN) |
4crm | TRANSLATIONINITIATION FACTORRLI1 (Saccharomycescerevisiae) | 4 / 6 | ASN P 5ASN P 74ILE P 56GLY P 57 | NoneNoneNoneSF4 P1610 ( 4.9A) | 0.95A | 1oniA-4crmP:undetectable1oniB-4crmP:undetectable | 1oniA-4crmP:14.111oniB-4crmP:14.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ONI_D_BEZD508_0 (14.5 KDATRANSLATIONALINHIBITOR PROTEIN) |
4crm | TRANSLATIONINITIATION FACTORRLI1 (Saccharomycescerevisiae) | 4 / 6 | ASN P 5ASN P 74ILE P 56GLY P 57 | NoneNoneNoneSF4 P1610 ( 4.9A) | 0.95A | 1oniD-4crmP:undetectable1oniF-4crmP:undetectable | 1oniD-4crmP:14.111oniF-4crmP:14.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1OPJ_A_STIA3_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | GLU A 305MET A 309ILE A 312VAL A 318THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.67A | 1opjA-1opkA:37.3 | 1opjA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1OPJ_A_STIA3_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309VAL A 318THR A 334PHE A 336LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.60A | 1opjA-1opkA:37.3 | 1opjA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1OPJ_A_STIA3_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 5 | LYS A 290VAL A 308ILE A 332MET A 337 | P16 A 2 (-4.5A)NoneP16 A 2 (-4.1A)None | 0.55A | 1opjA-1opkA:37.3 | 1opjA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1OPJ_A_STIA3_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 5 | TYR A 272VAL A 308ILE A 332MET A 337 | P16 A 2 (-3.6A)NoneP16 A 2 (-4.1A)None | 0.75A | 1opjA-1opkA:37.3 | 1opjA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1OPJ_B_STIB4_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | TYR A 272VAL A 275ALA A 288GLU A 305MET A 309VAL A 318THR A 334GLY A 340 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A) | 0.77A | 1opjB-1opkA:37.1 | 1opjB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1OPJ_B_STIB4_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 312VAL A 318THR A 334PHE A 336GLY A 340ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-3.5A) | 0.70A | 1opjB-1opkA:37.1 | 1opjB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1OPJ_B_STIB4_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267LYS A 290VAL A 308ILE A 332MET A 337 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)NoneP16 A 2 (-4.1A)None | 0.53A | 1opjB-1opkA:37.1 | 1opjB-1opkA:58.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1T46_A_STIA3_1 (HOMO SAPIENS V-KITHARDY-ZUCKERMAN 4FELINE SARCOMA VIRALONCOGENE HOMOLOG) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305VAL A 318THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.42A | 1t46A-1opkA:30.7 | 1t46A-1opkA:24.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWH_A_BAXA1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 12 | ALA A 288GLU A 305THR A 334LEU A 373HIS A 380 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)NoneNone | 0.54A | 1uwhA-1opkA:26.6 | 1uwhA-1opkA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWH_B_BAXB1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | ALA A 288LYS A 290GLU A 305THR A 334LEU A 373HIS A 380 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)NoneNone | 0.53A | 1uwhB-1opkA:26.5 | 1uwhB-1opkA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWJ_A_BAXA1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | VAL A 275ALA A 288GLU A 305THR A 334LEU A 373HIS A 380 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)NoneNone | 0.66A | 1uwjA-1opkA:7.1 | 1uwjA-1opkA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWJ_B_BAXB1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | VAL A 275ALA A 288GLU A 305THR A 334LEU A 373HIS A 380 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)NoneNone | 0.66A | 1uwjB-1opkA:7.1 | 1uwjB-1opkA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1XKK_A_FMMA91_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | THR A 334GLY A 340LEU A 343ASP A 344ARG A 347LEU A 389 | P16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneNoneNoneP16 A 2 (-4.4A) | 0.75A | 1xkkA-1opkA:29.2 | 1xkkA-1opkA:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1XKK_A_FMMA91_2 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 9 | LEU A 267VAL A 275LYS A 290LEU A 320MET A 337 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)NoneNone | 0.64A | 1xkkA-1opkA:29.2 | 1xkkA-1opkA:24.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2GQG_A_1N1A501_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305MET A 309VAL A 318ILE A 332THR A 334PHE A 336LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.82A | 2gqgA-1opkA:37.1 | 2gqgA-1opkA:57.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2GQG_A_1N1A501_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267ALA A 288LYS A 290MET A 309VAL A 318ILE A 332THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.80A | 2gqgA-1opkA:37.1 | 2gqgA-1opkA:57.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2GQG_B_1N1B502_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309VAL A 318ILE A 332THR A 334LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.57A | 2gqgB-1opkA:37.9 | 2gqgB-1opkA:57.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2GQG_B_1N1B502_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288MET A 309VAL A 318ILE A 332THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.62A | 2gqgB-1opkA:37.9 | 2gqgB-1opkA:57.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2GQG_B_1N1B502_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288LYS A 290GLU A 305MET A 309VAL A 318ILE A 332THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.59A | 2gqgB-1opkA:37.9 | 2gqgB-1opkA:57.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2GQG_B_1N1B502_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288LYS A 290MET A 309VAL A 318ILE A 332THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.59A | 2gqgB-1opkA:37.9 | 2gqgB-1opkA:57.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_A_STIA600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | TYR A 272VAL A 275ALA A 288GLU A 305MET A 309THR A 334PHE A 336GLY A 340LEU A 389 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.87A | 2hyyA-1opkA:34.9 | 2hyyA-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_A_STIA600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.78A | 2hyyA-1opkA:34.9 | 2hyyA-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_A_STIA600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.59A | 2hyyA-1opkA:34.9 | 2hyyA-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_A_STIA600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LYS A 290VAL A 308VAL A 318ILE A 332ARG A 381 | P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 1.01A | 2hyyA-1opkA:34.9 | 2hyyA-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_B_STIB600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | TYR A 272VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.88A | 2hyyB-1opkA:34.7 | 2hyyB-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_B_STIB600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.69A | 2hyyB-1opkA:34.7 | 2hyyB-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_B_STIB600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.54A | 2hyyB-1opkA:34.7 | 2hyyB-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_B_STIB600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | LEU A 267VAL A 308ILE A 332MET A 337 | P16 A 2 ( 4.2A)NoneP16 A 2 (-4.1A)None | 0.44A | 2hyyB-1opkA:34.7 | 2hyyB-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_C_STIC600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | TYR A 272VAL A 275ALA A 288GLU A 305ILE A 312VAL A 318THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.84A | 2hyyC-1opkA:35.2 | 2hyyC-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_C_STIC600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267LYS A 290VAL A 308MET A 309ILE A 332 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)NoneP16 A 2 (-3.3A)P16 A 2 (-4.1A) | 0.53A | 2hyyC-1opkA:35.2 | 2hyyC-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_C_STIC600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267VAL A 308MET A 309ILE A 332MET A 337 | P16 A 2 ( 4.2A)NoneP16 A 2 (-3.3A)P16 A 2 (-4.1A)None | 0.44A | 2hyyC-1opkA:35.2 | 2hyyC-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_D_STID600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | TYR A 272VAL A 275ALA A 288GLU A 305MET A 309ILE A 332THR A 334PHE A 336LEU A 389ALA A 399 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.87A | 2hyyD-1opkA:34.8 | 2hyyD-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_D_STID600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 312ILE A 332THR A 334PHE A 336LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.74A | 2hyyD-1opkA:34.8 | 2hyyD-1opkA:99.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_D_STID600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 4 | LEU A 267LYS A 290VAL A 318MET A 337 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)None | 0.58A | 2hyyD-1opkA:34.8 | 2hyyD-1opkA:99.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ITO_A_IREA2020_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305MET A 309THR A 334GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A) | 0.81A | 2itoA-1opkA:30.3 | 2itoA-1opkA:25.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ITO_A_IREA2020_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.83A | 2itoA-1opkA:30.3 | 2itoA-1opkA:25.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ITY_A_IREA2020_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305MET A 309THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.94A | 2ityA-1opkA:30.3 | 2ityA-1opkA:24.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ITZ_A_IREA2021_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305MET A 309THR A 334GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A) | 0.82A | 2itzA-1opkA:30.1 | 2itzA-1opkA:24.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ITZ_A_IREA2021_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.89A | 2itzA-1opkA:30.1 | 2itzA-1opkA:24.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2OIQ_A_STIA1001_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288LYS A 290GLU A 305MET A 309ILE A 332THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.69A | 2oiqA-1opkA:31.7 | 2oiqA-1opkA:30.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PL0_A_STIA200_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE LCK) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288GLU A 305MET A 309VAL A 318ILE A 332THR A 334LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.74A | 2pl0A-1opkA:30.2 | 2pl0A-1opkA:28.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PL0_A_STIA200_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE LCK) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288LYS A 290GLU A 305MET A 309VAL A 318ILE A 332THR A 334ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.5A) | 0.72A | 2pl0A-1opkA:30.2 | 2pl0A-1opkA:28.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PL0_A_STIA200_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE LCK) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 332THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.87A | 2pl0A-1opkA:30.2 | 2pl0A-1opkA:28.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PL0_A_STIA200_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE LCK) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | VAL A 275ALA A 288LYS A 290GLU A 305MET A 309ILE A 332THR A 334ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.5A) | 0.78A | 2pl0A-1opkA:30.2 | 2pl0A-1opkA:28.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2XP2_A_VGHA9000_1 (TYROSINE-PROTEINKINASE RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 9 | LEU A 267VAL A 275ALA A 288MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.58A | 2xp2A-1opkA:30.8 | 2xp2A-1opkA:25.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y6O_A_1N1A1892_1 (EPHRIN TYPE-ARECEPTOR 4) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288LYS A 290GLU A 305MET A 309ILE A 332THR A 334GLY A 340LEU A 389 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.61A | 2y6oA-1opkA:31.7 | 2y6oA-1opkA:26.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2YFX_A_VGHA9000_1 (TYROSINE-PROTEINKINASE RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 8 | LEU A 267ALA A 288MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.50A | 2yfxA-1opkA:30.6 | 2yfxA-1opkA:25.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZJ0_A_2FAA500_2 (ADENOSYLHOMOCYSTEINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 5 | GLN A 319THR A 334HIS A 380LEU A 403 | NoneP16 A 2 (-3.7A)NoneNone | 1.39A | 2zj0A-1opkA:undetectable | 2zj0A-1opkA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZVA_A_1N1A513_1 (TYROSINE-PROTEINKINASE LYN) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305MET A 309VAL A 318ILE A 332THR A 334MET A 337LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.76A | 2zvaA-1opkA:32.2 | 2zvaA-1opkA:28.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ZVA_A_1N1A513_1 (TYROSINE-PROTEINKINASE LYN) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267ALA A 288LYS A 290MET A 309VAL A 318ILE A 332THR A 334MET A 337GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.77A | 2zvaA-1opkA:32.2 | 2zvaA-1opkA:28.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3AOX_A_EMHA901_1 (ALK TYROSINE KINASERECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 10 | LEU A 267ALA A 288VAL A 318MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 ( 4.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.74A | 3aoxA-1opkA:30.4 | 3aoxA-1opkA:27.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3C7Q_A_XINA1172_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267GLU A 277ALA A 288LYS A 290VAL A 318PHE A 336GLY A 340LEU A 389 | P16 A 2 ( 4.2A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.60A | 3c7qA-1opkA:29.6 | 3c7qA-1opkA:26.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_A_NILA600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 10 | LEU A 267TYR A 272VAL A 275LYS A 290LYS A 304ILE A 332PHE A 336 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)NoneP16 A 2 (-4.1A)P16 A 2 ( 4.4A) | 0.98A | 3cs9A-1opkA:34.8 | 3cs9A-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_A_NILA600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 10 | LEU A 267TYR A 272VAL A 275LYS A 290VAL A 318ILE A 332PHE A 336 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 ( 4.4A) | 0.82A | 3cs9A-1opkA:34.8 | 3cs9A-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_A_NILA600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 10 | LEU A 267VAL A 275LYS A 290VAL A 318ILE A 332PHE A 336VAL A 398 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 ( 4.4A)None | 0.64A | 3cs9A-1opkA:34.8 | 3cs9A-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_A_NILA600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | ALA A 288GLU A 305VAL A 308MET A 309LEU A 317THR A 334GLY A 340HIS A 380LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneP16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.59A | 3cs9A-1opkA:34.8 | 3cs9A-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_A_NILA600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | GLU A 305VAL A 308MET A 309ILE A 312LEU A 317THR A 334GLY A 340HIS A 380LEU A 389ALA A 399 | P16 A 2 (-4.2A)NoneP16 A 2 (-3.3A)NoneNoneP16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.70A | 3cs9A-1opkA:34.8 | 3cs9A-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_B_NILB600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | ALA A 288GLU A 305VAL A 308MET A 309ILE A 312LEU A 317THR A 334GLY A 340HIS A 380ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneP16 A 2 (-3.3A)NoneNoneP16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.5A) | 0.66A | 3cs9B-1opkA:34.3 | 3cs9B-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_B_NILB600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 9 | LEU A 267TYR A 272VAL A 275LYS A 290VAL A 318ILE A 332LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-4.4A) | 0.73A | 3cs9B-1opkA:34.3 | 3cs9B-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_B_NILB600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 9 | LEU A 267VAL A 275LYS A 290VAL A 318ILE A 332LEU A 389VAL A 398 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-4.4A)None | 0.53A | 3cs9B-1opkA:34.3 | 3cs9B-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_B_NILB600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 9 | LEU A 267VAL A 275VAL A 318ILE A 332PHE A 378LEU A 389VAL A 398 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)NoneP16 A 2 (-4.4A)None | 0.68A | 3cs9B-1opkA:34.3 | 3cs9B-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_C_NILC600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | ALA A 288GLU A 305VAL A 308MET A 309ILE A 312LEU A 317THR A 334PHE A 336HIS A 380ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneP16 A 2 (-3.3A)NoneNoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.5A) | 0.68A | 3cs9C-1opkA:34.2 | 3cs9C-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_C_NILC600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | VAL A 308MET A 309ILE A 312LEU A 317THR A 334PHE A 378 | NoneP16 A 2 (-3.3A)NoneNoneP16 A 2 (-3.7A)None | 1.37A | 3cs9C-1opkA:34.2 | 3cs9C-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_C_NILC600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 9 | LEU A 267VAL A 275LYS A 290VAL A 318ILE A 332MET A 337VAL A 398 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)NoneNone | 0.64A | 3cs9C-1opkA:34.2 | 3cs9C-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_C_NILC600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 9 | TYR A 272VAL A 275VAL A 318ILE A 332MET A 337 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 1.00A | 3cs9C-1opkA:34.2 | 3cs9C-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_D_NILD600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | ALA A 288GLU A 305VAL A 308MET A 309LEU A 317THR A 334PHE A 336GLY A 340HIS A 380ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneP16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.5A) | 0.59A | 3cs9D-1opkA:33.0 | 3cs9D-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_D_NILD600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | GLU A 305VAL A 308MET A 309ILE A 312LEU A 317THR A 334GLY A 340HIS A 380ALA A 399 | P16 A 2 (-4.2A)NoneP16 A 2 (-3.3A)NoneNoneP16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.5A) | 0.72A | 3cs9D-1opkA:33.0 | 3cs9D-1opkA:57.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_D_NILD600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267TYR A 272VAL A 275LYS A 290LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)P16 A 2 (-4.4A) | 0.72A | 3cs9D-1opkA:33.0 | 3cs9D-1opkA:57.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G0E_A_B49A9000_1 (MAST/STEM CELLGROWTH FACTORRECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 11 | LEU A 267VAL A 275ALA A 288VAL A 318THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.39A | 3g0eA-1opkA:29.3 | 3g0eA-1opkA:26.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G0F_A_B49A9001_1 (MAST/STEM CELLGROWTH FACTORRECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 11 | LEU A 267VAL A 275ALA A 288THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.38A | 3g0fA-1opkA:30.2 | 3g0fA-1opkA:26.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G0F_B_B49B9001_1 (MAST/STEM CELLGROWTH FACTORRECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 10 | LEU A 267VAL A 275ALA A 288THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.33A | 3g0fB-1opkA:30.5 | 3g0fB-1opkA:26.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3G5D_A_1N1A1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309VAL A 318ILE A 332THR A 334LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.58A | 3g5dA-1opkA:32.4 | 3g5dA-1opkA:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3G5D_A_1N1A1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288MET A 309VAL A 318ILE A 332THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.64A | 3g5dA-1opkA:32.4 | 3g5dA-1opkA:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3G5D_B_1N1B1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305MET A 309VAL A 318THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.78A | 3g5dB-1opkA:32.5 | 3g5dB-1opkA:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GVU_A_STIA1001_1 (TYROSINE-PROTEINKINASE ABL2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309VAL A 318THR A 334LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.61A | 3gvuA-1opkA:35.4 | 3gvuA-1opkA:54.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GVU_A_STIA1001_1 (TYROSINE-PROTEINKINASE ABL2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | TYR A 272VAL A 275ALA A 288GLU A 305MET A 309VAL A 318THR A 334LEU A 389 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-4.4A) | 0.85A | 3gvuA-1opkA:35.4 | 3gvuA-1opkA:54.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GVU_A_STIA1001_1 (TYROSINE-PROTEINKINASE ABL2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 312VAL A 318THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.72A | 3gvuA-1opkA:35.4 | 3gvuA-1opkA:54.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GVU_A_STIA1001_2 (TYROSINE-PROTEINKINASE ABL2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 5 | LYS A 290VAL A 308ILE A 332MET A 337 | P16 A 2 (-4.5A)NoneP16 A 2 (-4.1A)None | 0.60A | 3gvuA-1opkA:35.4 | 3gvuA-1opkA:54.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3IK3_A_0LIA1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288GLU A 305MET A 309ILE A 312LEU A 317HIS A 380LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneNoneNoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.59A | 3ik3A-1opkA:34.8 | 3ik3A-1opkA:57.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3IK3_A_0LIA1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | GLU A 305MET A 309LEU A 317VAL A 318HIS A 380LEU A 389 | P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)NoneP16 A 2 (-4.4A) | 0.63A | 3ik3A-1opkA:34.8 | 3ik3A-1opkA:57.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3IK3_A_0LIA1_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 7 | LEU A 267LYS A 290VAL A 308ILE A 332 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)NoneP16 A 2 (-4.1A) | 0.53A | 3ik3A-1opkA:34.8 | 3ik3A-1opkA:57.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3IK3_A_0LIA1_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 7 | LEU A 267VAL A 308ILE A 332MET A 337 | P16 A 2 ( 4.2A)NoneP16 A 2 (-4.1A)None | 0.34A | 3ik3A-1opkA:34.8 | 3ik3A-1opkA:57.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3IK3_B_0LIB2_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288GLU A 305MET A 309ILE A 312LEU A 317HIS A 380LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneNoneNoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.57A | 3ik3B-1opkA:34.6 | 3ik3B-1opkA:57.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3IK3_B_0LIB2_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | GLU A 305MET A 309LEU A 317VAL A 318HIS A 380LEU A 389 | P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)NoneP16 A 2 (-4.4A) | 0.67A | 3ik3B-1opkA:34.6 | 3ik3B-1opkA:57.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3IK3_B_0LIB2_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 7 | LEU A 267LYS A 290VAL A 308ILE A 332 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)NoneP16 A 2 (-4.1A) | 0.50A | 3ik3B-1opkA:34.6 | 3ik3B-1opkA:57.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3IK3_B_0LIB2_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 7 | LEU A 267VAL A 308ILE A 332MET A 337 | P16 A 2 ( 4.2A)NoneP16 A 2 (-4.1A)None | 0.35A | 3ik3B-1opkA:34.6 | 3ik3B-1opkA:57.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3K54_A_1N1A1_1 (TYROSINE-PROTEINKINASE BTK) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305MET A 309VAL A 318ILE A 332THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.79A | 3k54A-1opkA:30.3 | 3k54A-1opkA:29.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3K5V_A_STIA2_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | TYR A 272VAL A 275ALA A 288GLU A 305MET A 309THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.81A | 3k5vA-1opkA:37.0 | 3k5vA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3K5V_A_STIA2_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.71A | 3k5vA-1opkA:37.0 | 3k5vA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3K5V_A_STIA2_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.52A | 3k5vA-1opkA:37.0 | 3k5vA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3K5V_A_STIA2_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | LEU A 267VAL A 308ILE A 332MET A 337 | P16 A 2 ( 4.2A)NoneP16 A 2 (-4.1A)None | 0.45A | 3k5vA-1opkA:37.0 | 3k5vA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3K5V_B_STIB2_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | TYR A 272VAL A 275ALA A 288GLU A 305MET A 309THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.83A | 3k5vB-1opkA:37.2 | 3k5vB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3K5V_B_STIB2_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.68A | 3k5vB-1opkA:37.2 | 3k5vB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3K5V_B_STIB2_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.50A | 3k5vB-1opkA:37.2 | 3k5vB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3K5V_B_STIB2_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267VAL A 308VAL A 318ILE A 332MET A 337 | P16 A 2 ( 4.2A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 0.47A | 3k5vB-1opkA:37.2 | 3k5vB-1opkA:58.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LFA_A_1N1A361_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 8 | ALA A 288LYS A 290GLU A 305THR A 334MET A 337 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)None | 0.45A | 3lfaA-1opkA:19.7 | 3lfaA-1opkA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIY_A_B49A1_1 (TYROSINE-PROTEINKINASE ITK/TSK) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 11 | ALA A 288VAL A 318PHE A 336MET A 337GLY A 340LEU A 389 | P16 A 2 (-3.4A)P16 A 2 ( 4.7A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.74A | 3miyA-1opkA:30.8 | 3miyA-1opkA:26.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIY_B_B49B2_1 (TYROSINE-PROTEINKINASE ITK/TSK) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 9 | ALA A 288PHE A 336MET A 337GLY A 340LEU A 389 | P16 A 2 (-3.4A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.59A | 3miyB-1opkA:31.0 | 3miyB-1opkA:26.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MS9_A_STIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267TYR A 272VAL A 275ALA A 288GLU A 305MET A 309THR A 334PHE A 336LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A) | 0.79A | 3ms9A-1opkA:34.3 | 3ms9A-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MS9_A_STIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.76A | 3ms9A-1opkA:34.3 | 3ms9A-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MS9_A_STIA1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LYS A 290VAL A 308VAL A 318ILE A 332MET A 337 | P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 0.57A | 3ms9A-1opkA:34.3 | 3ms9A-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MS9_A_STIA1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LYS A 290VAL A 318ILE A 332MET A 337ARG A 381 | P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)NoneNone | 0.95A | 3ms9A-1opkA:34.3 | 3ms9A-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MS9_B_STIB1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.74A | 3ms9B-1opkA:34.5 | 3ms9B-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MS9_B_STIB1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 7 | LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.54A | 3ms9B-1opkA:34.5 | 3ms9B-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MS9_B_STIB1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 7 | TYR A 272VAL A 308VAL A 318ILE A 332MET A 337 | P16 A 2 (-3.6A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 0.70A | 3ms9B-1opkA:34.5 | 3ms9B-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_A_STIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267TYR A 272VAL A 275ALA A 288GLU A 305MET A 309THR A 334LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-4.4A) | 0.76A | 3mssA-1opkA:34.5 | 3mssA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_A_STIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.74A | 3mssA-1opkA:34.5 | 3mssA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_A_STIA1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.47A | 3mssA-1opkA:34.5 | 3mssA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_A_STIA1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | LYS A 290VAL A 318ILE A 332ARG A 381 | P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 0.97A | 3mssA-1opkA:34.5 | 3mssA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_A_STIA1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | VAL A 308VAL A 318ILE A 332MET A 337 | NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 0.46A | 3mssA-1opkA:34.5 | 3mssA-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_B_STIB1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | GLU A 305MET A 309ILE A 312GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.64A | 3mssB-1opkA:34.6 | 3mssB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_B_STIB1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | GLU A 305MET A 309ILE A 312THR A 334GLY A 340LEU A 389 | P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.60A | 3mssB-1opkA:34.6 | 3mssB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_B_STIB1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.68A | 3mssB-1opkA:34.6 | 3mssB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_B_STIB1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309THR A 334PHE A 336GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.63A | 3mssB-1opkA:34.6 | 3mssB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_B_STIB1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 7 | TYR A 272LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.90A | 3mssB-1opkA:34.6 | 3mssB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_B_STIB1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 7 | TYR A 272VAL A 308VAL A 318ILE A 332MET A 337 | P16 A 2 (-3.6A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 0.73A | 3mssB-1opkA:34.6 | 3mssB-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_C_STIC1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267TYR A 272VAL A 275ALA A 288GLU A 305MET A 309THR A 334LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-4.4A) | 0.78A | 3mssC-1opkA:34.5 | 3mssC-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_C_STIC1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.75A | 3mssC-1opkA:34.5 | 3mssC-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_C_STIC1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.48A | 3mssC-1opkA:34.5 | 3mssC-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_C_STIC1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | LYS A 290VAL A 318ILE A 332ARG A 381 | P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 1.00A | 3mssC-1opkA:34.5 | 3mssC-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_C_STIC1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | VAL A 308VAL A 318ILE A 332MET A 337 | NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 0.48A | 3mssC-1opkA:34.5 | 3mssC-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_D_STID1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.79A | 3mssD-1opkA:34.6 | 3mssD-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_D_STID1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267TYR A 272ALA A 288GLU A 305MET A 309THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.84A | 3mssD-1opkA:34.6 | 3mssD-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_D_STID1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | VAL A 275LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 (-4.5A)P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.52A | 3mssD-1opkA:34.6 | 3mssD-1opkA:58.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3MSS_D_STID1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | VAL A 275VAL A 308VAL A 318ILE A 332MET A 337 | P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 0.50A | 3mssD-1opkA:34.6 | 3mssD-1opkA:58.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OCT_A_1N1A663_1 (TYROSINE-PROTEINKINASE BTK) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290MET A 309VAL A 318THR A 334GLY A 340GLU A 348LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-4.4A) | 1.12A | 3octA-1opkA:32.5 | 3octA-1opkA:28.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OEZ_A_STIA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288GLU A 305MET A 309ILE A 312THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.57A | 3oezA-1opkA:31.3 | 3oezA-1opkA:30.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OEZ_A_STIA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288GLU A 305MET A 309ILE A 312VAL A 318THR A 334GLY A 340LEU A 389 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.49A | 3oezA-1opkA:31.3 | 3oezA-1opkA:30.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OEZ_A_STIA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | VAL A 275ALA A 288GLU A 305MET A 309THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.69A | 3oezA-1opkA:31.3 | 3oezA-1opkA:30.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OEZ_A_STIA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | VAL A 275ALA A 288GLU A 305MET A 309VAL A 318THR A 334GLY A 340LEU A 389 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.63A | 3oezA-1opkA:31.3 | 3oezA-1opkA:30.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OEZ_B_STIB601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | ALA A 288LYS A 290GLU A 305VAL A 308MET A 309ILE A 332THR A 334LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)NoneP16 A 2 (-3.3A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.66A | 3oezB-1opkA:31.4 | 3oezB-1opkA:30.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OEZ_B_STIB601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | VAL A 275ALA A 288LYS A 290VAL A 308MET A 309ILE A 332THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)NoneP16 A 2 (-3.3A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.67A | 3oezB-1opkA:31.4 | 3oezB-1opkA:30.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OND_A_ADNA506_2 (ADENOSYLHOMOCYSTEINASE) |
4crm | TRANSLATIONINITIATION FACTORRLI1 (Saccharomycescerevisiae) | 3 / 3 | GLN P 127THR P 118LEU P 131 | NoneATP P1609 (-3.6A)None | 0.75A | 3ondA-4crmP:undetectable | 3ondA-4crmP:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OND_B_ADNB507_2 (ADENOSYLHOMOCYSTEINASE) |
4crm | TRANSLATIONINITIATION FACTORRLI1 (Saccharomycescerevisiae) | 3 / 3 | GLN P 127THR P 118LEU P 131 | NoneATP P1609 (-3.6A)None | 0.76A | 3ondB-4crmP:undetectable | 3ondB-4crmP:21.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OXZ_A_0LIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | ALA A 288GLU A 305MET A 309ILE A 312LEU A 317THR A 334GLY A 340HIS A 380ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneNoneP16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.5A) | 0.52A | 3oxzA-1opkA:34.6 | 3oxzA-1opkA:57.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OXZ_A_0LIA1_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | ALA A 288GLU A 305MET A 309ILE A 312LEU A 317VAL A 318THR A 334GLY A 340HIS A 380 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneNoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)None | 0.50A | 3oxzA-1opkA:34.6 | 3oxzA-1opkA:57.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OXZ_A_0LIA1_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 9 | LEU A 267LYS A 290VAL A 308ILE A 332MET A 337LEU A 389VAL A 398 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)NoneP16 A 2 (-4.1A)NoneP16 A 2 (-4.4A)None | 0.50A | 3oxzA-1opkA:34.6 | 3oxzA-1opkA:57.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3PYY_A_STIA3_1 (V-ABL ABELSON MURINELEUKEMIA VIRALONCOGENE HOMOLOG 1ISOFORM B VARIANT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A) | 0.53A | 3pyyA-1opkA:34.3 | 3pyyA-1opkA:59.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3PYY_A_STIA3_1 (V-ABL ABELSON MURINELEUKEMIA VIRALONCOGENE HOMOLOG 1ISOFORM B VARIANT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 312THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.67A | 3pyyA-1opkA:34.3 | 3pyyA-1opkA:59.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3PYY_A_STIA3_2 (V-ABL ABELSON MURINELEUKEMIA VIRALONCOGENE HOMOLOG 1ISOFORM B VARIANT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | LYS A 290VAL A 318ILE A 332ARG A 381 | P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)None | 1.02A | 3pyyA-1opkA:34.3 | 3pyyA-1opkA:59.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3PYY_A_STIA3_2 (V-ABL ABELSON MURINELEUKEMIA VIRALONCOGENE HOMOLOG 1ISOFORM B VARIANT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | TYR A 272LYS A 290VAL A 308VAL A 318ILE A 332 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A) | 0.92A | 3pyyA-1opkA:34.3 | 3pyyA-1opkA:59.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3PYY_B_STIB4_1 (V-ABL ABELSON MURINELEUKEMIA VIRALONCOGENE HOMOLOG 1ISOFORM B VARIANT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267TYR A 272VAL A 275ALA A 288GLU A 305MET A 309ILE A 312VAL A 318THR A 334LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-4.4A) | 0.77A | 3pyyB-1opkA:34.6 | 3pyyB-1opkA:59.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3PYY_B_STIB4_1 (V-ABL ABELSON MURINELEUKEMIA VIRALONCOGENE HOMOLOG 1ISOFORM B VARIANT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309ILE A 312VAL A 318THR A 334LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.59A | 3pyyB-1opkA:34.6 | 3pyyB-1opkA:59.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3PYY_B_STIB4_2 (V-ABL ABELSON MURINELEUKEMIA VIRALONCOGENE HOMOLOG 1ISOFORM B VARIANT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 5 | LYS A 290VAL A 308ILE A 332MET A 337ARG A 381 | P16 A 2 (-4.5A)NoneP16 A 2 (-4.1A)NoneNone | 0.93A | 3pyyB-1opkA:34.6 | 3pyyB-1opkA:59.18 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3QLG_A_1N1A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305MET A 309VAL A 318THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.81A | 3qlgA-1opkA:31.7 | 3qlgA-1opkA:30.51 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3QLG_B_1N1B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309VAL A 318THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.76A | 3qlgB-1opkA:32.0 | 3qlgB-1opkA:30.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3SXR_A_1N1A1_1 (CYTOPLASMICTYROSINE-PROTEINKINASE BMX) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288MET A 309VAL A 318ILE A 332THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.62A | 3sxrA-1opkA:33.1 | 3sxrA-1opkA:25.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3SXR_B_1N1B2_1 (CYTOPLASMICTYROSINE-PROTEINKINASE BMX) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288MET A 309VAL A 318THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.58A | 3sxrB-1opkA:32.9 | 3sxrB-1opkA:25.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3UE4_A_DB8A601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267ALA A 288GLU A 305THR A 334PHE A 336MET A 337GLY A 340LEU A 389PHE A 401 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A)None | 0.95A | 3ue4A-1opkA:37.4 | 3ue4A-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3UE4_A_DB8A601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305ILE A 332THR A 334PHE A 336MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.73A | 3ue4A-1opkA:37.4 | 3ue4A-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3UE4_A_DB8A601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267ALA A 288LYS A 290VAL A 318ILE A 332THR A 334PHE A 336MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.65A | 3ue4A-1opkA:37.4 | 3ue4A-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3UE4_A_DB8A601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267ALA A 288VAL A 318THR A 334PHE A 336MET A 337GLY A 340LEU A 389PHE A 401 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A)None | 0.78A | 3ue4A-1opkA:37.4 | 3ue4A-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3UE4_B_DB8B601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309VAL A 318ILE A 332THR A 334PHE A 336GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.67A | 3ue4B-1opkA:37.8 | 3ue4B-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3UE4_B_DB8B601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309VAL A 318THR A 334PHE A 336GLY A 340LEU A 389PHE A 401 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)None | 0.89A | 3ue4B-1opkA:37.8 | 3ue4B-1opkA:57.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3UG2_A_IREA1_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290MET A 337GLY A 340ASP A 344LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)NoneP16 A 2 (-3.4A)NoneP16 A 2 (-4.4A) | 0.81A | 3ug2A-1opkA:31.8 | 3ug2A-1opkA:25.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WZD_A_LEVA1201_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 12 | LEU A 267GLY A 268VAL A 275ALA A 288GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 ( 4.3A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.4A) | 0.40A | 3wzdA-1opkA:30.6 | 3wzdA-1opkA:25.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WZD_A_LEVA1201_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.4A) | 0.37A | 3wzdA-1opkA:30.6 | 3wzdA-1opkA:25.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WZE_A_BAXA1201_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305PHE A 336GLY A 340LEU A 373HIS A 380 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)NoneNone | 0.44A | 3wzeA-1opkA:30.3 | 3wzeA-1opkA:25.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WZE_A_BAXA1201_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305PHE A 336GLY A 340HIS A 380 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)None | 0.54A | 3wzeA-1opkA:30.3 | 3wzeA-1opkA:25.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZOS_A_0LIA1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305THR A 334LEU A 373HIS A 380ARG A 381LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)NoneNoneNoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.90A | 3zosA-1opkA:29.5 | 3zosA-1opkA:26.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZOS_B_0LIB1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | ALA A 288LYS A 290GLU A 305THR A 334LEU A 373HIS A 380ARG A 381LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)NoneNoneNoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.92A | 3zosB-1opkA:29.4 | 3zosB-1opkA:26.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AG8_A_AXIA2000_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305VAL A 318PHE A 336GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 ( 4.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.44A | 4ag8A-1opkA:30.7 | 4ag8A-1opkA:26.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AGC_A_AXIA2000_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.47A | 4agcA-1opkA:30.2 | 4agcA-1opkA:28.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AGD_A_B49A2000_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 11 | LEU A 267ALA A 288VAL A 318PHE A 336GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 ( 4.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.35A | 4agdA-1opkA:29.8 | 4agdA-1opkA:28.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ANQ_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 9 | LEU A 267VAL A 275ALA A 288MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.56A | 4anqA-1opkA:30.6 | 4anqA-1opkA:27.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ANS_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 9 | LEU A 267VAL A 275ALA A 288MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.57A | 4ansA-1opkA:30.5 | 4ansA-1opkA:27.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ASD_A_BAXA1500_1 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305PHE A 336GLY A 340LEU A 373HIS A 380 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)NoneNone | 0.62A | 4asdA-1opkA:30.0 | 4asdA-1opkA:28.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_A_STIA1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | VAL A 275ALA A 288GLU A 305MET A 309THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.93A | 4bkjA-1opkA:28.8 | 4bkjA-1opkA:26.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_B_STIB1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | VAL A 275ALA A 288GLU A 305MET A 309THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.80A | 4bkjB-1opkA:28.8 | 4bkjB-1opkA:26.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C8B_A_0LIA1000_1 (RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288LYS A 290GLU A 305ILE A 332THR A 334HIS A 380LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.50A | 4c8bA-1opkA:25.4 | 4c8bA-1opkA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C8B_B_0LIB1000_1 (RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | ALA A 288LYS A 290GLU A 305THR A 334HIS A 380LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.47A | 4c8bB-1opkA:25.6 | 4c8bB-1opkA:20.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4CSV_A_STIA1265_1 (SRC-ABL TYROSINEKINASE ANCESTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | VAL A 275ALA A 288GLU A 305MET A 309THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.65A | 4csvA-1opkA:32.5 | 4csvA-1opkA:47.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4CSV_A_STIA1265_1 (SRC-ABL TYROSINEKINASE ANCESTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | VAL A 275ALA A 288GLU A 305MET A 309VAL A 318THR A 334LEU A 389 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-4.4A) | 0.63A | 4csvA-1opkA:32.5 | 4csvA-1opkA:47.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4CSV_A_STIA1265_2 (SRC-ABL TYROSINEKINASE ANCESTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 4 | LYS A 290ILE A 332MET A 337PHE A 378 | P16 A 2 (-4.5A)P16 A 2 (-4.1A)NoneNone | 0.63A | 4csvA-1opkA:32.2 | 4csvA-1opkA:47.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290THR A 334MET A 337LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.7A)NoneP16 A 2 (-4.4A) | 0.67A | 4hjoA-1opkA:29.7 | 4hjoA-1opkA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4HJO_A_AQ4A1001_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267VAL A 275ALA A 288THR A 334MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.63A | 4hjoA-1opkA:29.7 | 4hjoA-1opkA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MKC_A_4MKA1503_1 (ALK TYROSINE KINASERECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267GLY A 273VAL A 275ALA A 288LYS A 290GLY A 340LEU A 389 | P16 A 2 ( 4.2A)NoneP16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.87A | 4mkcA-1opkA:30.9 | 4mkcA-1opkA:28.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXO_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305MET A 309VAL A 318ILE A 332THR A 334 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A) | 0.72A | 4mxoA-1opkA:32.1 | 4mxoA-1opkA:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXO_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290MET A 309VAL A 318ILE A 332THR A 334GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A) | 0.86A | 4mxoA-1opkA:32.1 | 4mxoA-1opkA:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXO_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305VAL A 318ILE A 332THR A 334 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A) | 0.70A | 4mxoB-1opkA:32.1 | 4mxoB-1opkA:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXO_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290VAL A 318ILE A 332THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.73A | 4mxoB-1opkA:32.1 | 4mxoB-1opkA:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXX_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288LYS A 290GLU A 305MET A 309VAL A 318THR A 334GLY A 340LEU A 389 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.88A | 4mxxA-1opkA:32.1 | 4mxxA-1opkA:30.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXX_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | ALA A 288LYS A 290GLU A 305VAL A 318ILE A 332THR A 334GLY A 340LEU A 389 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.78A | 4mxxA-1opkA:32.1 | 4mxxA-1opkA:30.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXX_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305ILE A 332THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.93A | 4mxxA-1opkA:32.1 | 4mxxA-1opkA:30.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXX_A_DB8A601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305MET A 309THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 1.04A | 4mxxA-1opkA:32.1 | 4mxxA-1opkA:30.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXX_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290VAL A 318THR A 334MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.78A | 4mxxB-1opkA:31.6 | 4mxxB-1opkA:30.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXY_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290VAL A 318GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.96A | 4mxyB-1opkA:32.1 | 4mxyB-1opkA:29.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXZ_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290VAL A 318GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.96A | 4mxzB-1opkA:32.1 | 4mxzB-1opkA:29.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OTW_A_DB8A1101_1 (RECEPTORTYROSINE-PROTEINKINASE ERBB-3) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267VAL A 275LYS A 290VAL A 318GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.90A | 4otwA-1opkA:28.5 | 4otwA-1opkA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OTW_A_DB8A1101_1 (RECEPTORTYROSINE-PROTEINKINASE ERBB-3) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267VAL A 275LYS A 290VAL A 318THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.74A | 4otwA-1opkA:28.5 | 4otwA-1opkA:24.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMN_A_DB8A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | ALA A 288LYS A 290GLU A 305ILE A 332LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-4.1A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.80A | 4qmnA-1opkA:26.0 | 4qmnA-1opkA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QRC_A_0LIA802_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | ALA A 288GLU A 305MET A 309LEU A 373ARG A 381ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneNoneP16 A 2 (-3.5A) | 0.83A | 4qrcA-1opkA:30.7 | 4qrcA-1opkA:29.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QRC_A_0LIA802_2 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 8 | LEU A 267VAL A 275LYS A 290HIS A 380LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)NoneP16 A 2 (-4.4A) | 0.48A | 4qrcA-1opkA:30.7 | 4qrcA-1opkA:29.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4R7I_A_STIA1001_1 (MACROPHAGECOLONY-STIMULATINGFACTOR 1 RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | VAL A 275ALA A 288LYS A 290GLU A 305MET A 309THR A 334LEU A 389 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-4.4A) | 0.45A | 4r7iA-1opkA:30.3 | 4r7iA-1opkA:26.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RJD_B_TFPB204_1 (CALMODULIN) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 8 | LEU A 395GLY A 391GLU A 392ALA A 288 | NoneGOL A 3 (-4.9A)GOL A 3 (-4.5A)P16 A 2 (-3.4A) | 0.88A | 4rjdA-1opkA:0.04rjdB-1opkA:0.0 | 4rjdA-1opkA:12.434rjdB-1opkA:12.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4TWP_A_AXIA601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290PHE A 336MET A 337GLY A 340ASN A 387LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.50A | 4twpA-1opkA:37.7 | 4twpA-1opkA:98.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4TWP_A_AXIA601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | TYR A 272VAL A 275ALA A 288LYS A 290PHE A 336MET A 337GLY A 340LEU A 389ALA A 399 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.91A | 4twpA-1opkA:37.7 | 4twpA-1opkA:98.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4TWP_B_AXIB601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267TYR A 272VAL A 275ALA A 288LYS A 290PHE A 336MET A 337GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.80A | 4twpB-1opkA:38.4 | 4twpB-1opkA:98.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4TWP_B_AXIB601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290PHE A 336MET A 337GLY A 340ASN A 387LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.51A | 4twpB-1opkA:38.4 | 4twpB-1opkA:98.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4TYJ_A_0LIA801_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | ALA A 288GLU A 305MET A 309ILE A 312HIS A 380LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneNoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.64A | 4tyjA-1opkA:30.8 | 4tyjA-1opkA:28.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4U0I_A_0LIA1001_2 (MAST/STEM CELLGROWTH FACTORRECEPTORKIT,MAST/STEM CELLGROWTH FACTORRECEPTOR KIT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | ALA A 288LYS A 290THR A 334GLY A 340HIS A 380LEU A 389 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-4.4A) | 0.47A | 4u0iA-1opkA:30.5 | 4u0iA-1opkA:24.95 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4U5J_A_RXTA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 11 | LEU A 267VAL A 275ALA A 288MET A 337GLY A 340ASN A 387LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.4A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.64A | 4u5jA-1opkA:33.6 | 4u5jA-1opkA:30.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4U5J_B_RXTB601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 9 | LEU A 267VAL A 275ALA A 288MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.48A | 4u5jB-1opkA:32.9 | 4u5jB-1opkA:30.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4UXQ_A_0LIA1752_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | ALA A 288GLU A 305ILE A 312LEU A 373HIS A 380LEU A 389 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneNoneNoneP16 A 2 (-4.4A) | 0.85A | 4uxqA-1opkA:30.4 | 4uxqA-1opkA:28.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4UXQ_A_0LIA1752_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267ALA A 288GLU A 305LEU A 373HIS A 380LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneNoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.66A | 4uxqA-1opkA:30.4 | 4uxqA-1opkA:28.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4V01_A_0LIA1776_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | ALA A 288GLU A 305MET A 309ILE A 312LEU A 373HIS A 380ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneNoneNoneP16 A 2 (-3.5A) | 0.85A | 4v01A-1opkA:29.9 | 4v01A-1opkA:27.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4V01_B_0LIB1770_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | ALA A 288GLU A 305MET A 309LEU A 373HIS A 380ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneNoneP16 A 2 (-3.5A) | 0.59A | 4v01B-1opkA:30.1 | 4v01B-1opkA:27.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4V04_A_0LIA1772_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | VAL A 275ALA A 288GLU A 305HIS A 380ALA A 399GLY A 402 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneP16 A 2 (-3.5A)None | 1.08A | 4v04A-1opkA:29.6 | 4v04A-1opkA:27.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4V04_A_0LIA1772_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | VAL A 275ALA A 288GLU A 305LEU A 373HIS A 380ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneNoneP16 A 2 (-3.5A) | 0.63A | 4v04A-1opkA:29.6 | 4v04A-1opkA:27.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4V04_B_0LIB1771_2 (FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 12 | ALA A 288GLU A 305LEU A 373HIS A 380ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)NoneNoneP16 A 2 (-3.5A) | 0.63A | 4v04B-1opkA:29.8 | 4v04B-1opkA:27.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4WA9_A_AXIA9000_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 11 | ALA A 288THR A 334MET A 337GLY A 340ASN A 387LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.52A | 4wa9A-1opkA:33.1 | 4wa9A-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4WA9_A_AXIA9000_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 11 | LEU A 267ALA A 288LYS A 290THR A 334MET A 337LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.7A)NoneP16 A 2 (-4.4A) | 1.01A | 4wa9A-1opkA:33.1 | 4wa9A-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4WA9_A_AXIA9000_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 11 | LEU A 267ALA A 288THR A 334MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.84A | 4wa9A-1opkA:33.1 | 4wa9A-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4WA9_A_AXIA9000_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 11 | TYR A 272ALA A 288THR A 334MET A 337GLY A 340LEU A 389ALA A 399 | P16 A 2 (-3.6A)P16 A 2 (-3.4A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.85A | 4wa9A-1opkA:33.1 | 4wa9A-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4WA9_B_AXIB9000_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | TYR A 272VAL A 275ALA A 288THR A 334MET A 337GLY A 340LEU A 389ALA A 399 | P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.79A | 4wa9B-1opkA:37.8 | 4wa9B-1opkA:57.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4WA9_B_AXIB9000_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288LYS A 290THR A 334PHE A 336MET A 337GLY A 340ASN A 387LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A)NoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.54A | 4wa9B-1opkA:37.8 | 4wa9B-1opkA:57.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WBO_C_ANWC601_0 (RHODOPSIN KINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 6 | LEU A 267ALA A 288MET A 337LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)NoneP16 A 2 (-4.4A) | 0.50A | 4wboC-1opkA:22.0 | 4wboC-1opkA:26.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WKQ_A_IREA1101_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267ALA A 288GLU A 305THR A 334GLY A 340ASP A 344LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-4.4A) | 0.88A | 4wkqA-1opkA:32.1 | 4wkqA-1opkA:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WKQ_A_IREA1101_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305MET A 309THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.76A | 4wkqA-1opkA:32.1 | 4wkqA-1opkA:24.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XEY_A_1N1A601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 12 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290MET A 309VAL A 318ILE A 332THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.63A | 4xeyA-1opkA:37.1 | 4xeyA-1opkA:80.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XEY_B_1N1B601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290VAL A 318ILE A 332THR A 334PHE A 336LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A) | 0.60A | 4xeyB-1opkA:36.3 | 4xeyB-1opkA:80.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XEY_B_1N1B601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267VAL A 275ALA A 288VAL A 318ILE A 332THR A 334PHE A 336GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.62A | 4xeyB-1opkA:36.3 | 4xeyB-1opkA:80.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XEY_B_1N1B601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288LYS A 290MET A 309VAL A 318ILE A 332THR A 334PHE A 336LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.52A | 4xeyB-1opkA:36.3 | 4xeyB-1opkA:80.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XEY_B_1N1B601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288MET A 309VAL A 318ILE A 332THR A 334PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.47A | 4xeyB-1opkA:36.3 | 4xeyB-1opkA:80.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XLI_A_1N1A601_1 (NON-SPECIFICPROTEIN-TYROSINEKINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305MET A 309VAL A 318THR A 334MET A 337GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.72A | 4xliA-1opkA:36.5 | 4xliA-1opkA:92.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4XLI_B_1N1B600_1 (NON-SPECIFICPROTEIN-TYROSINEKINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305MET A 309VAL A 318ILE A 332THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.68A | 4xliB-1opkA:36.7 | 4xliB-1opkA:92.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ZAU_A_YY3A1101_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 8 | LEU A 267VAL A 275ALA A 288MET A 337GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.4A) | 0.59A | 4zauA-1opkA:31.9 | 4zauA-1opkA:24.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5AAA_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 9 | LEU A 267VAL A 275ALA A 288MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.56A | 5aaaA-1opkA:31.0 | 5aaaA-1opkA:26.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5AAB_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 10 | LEU A 267VAL A 275ALA A 288LYS A 290MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.65A | 5aabA-1opkA:31.0 | 5aabA-1opkA:26.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5AAC_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 10 | LEU A 267VAL A 275ALA A 288LYS A 290MET A 337GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.74A | 5aacA-1opkA:30.9 | 5aacA-1opkA:25.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5AJQ_A_DB8A800_1 (SERINE/THREONINE-PROTEIN KINASE 10) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267ALA A 288LYS A 290PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 1.04A | 5ajqA-1opkA:22.7 | 5ajqA-1opkA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5AJQ_A_DB8A800_1 (SERINE/THREONINE-PROTEIN KINASE 10) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267GLY A 268ALA A 288PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 ( 4.3A)P16 A 2 (-3.4A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.98A | 5ajqA-1opkA:22.7 | 5ajqA-1opkA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5AJQ_B_DB8B800_1 (SERINE/THREONINE-PROTEIN KINASE 10) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 10 | ALA A 288PHE A 336GLY A 340LEU A 389ALA A 399 | P16 A 2 (-3.4A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.68A | 5ajqB-1opkA:23.0 | 5ajqB-1opkA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5BVW_A_1N1A1009_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305MET A 309THR A 334GLY A 340LEU A 389ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.59A | 5bvwA-1opkA:29.8 | 5bvwA-1opkA:26.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5H2U_A_1N1A501_1 (PROTEIN-TYROSINEKINASE 6) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | LEU A 267VAL A 275ALA A 288THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.74A | 5h2uA-1opkA:29.5 | 5h2uA-1opkA:25.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5H2U_B_1N1B501_1 (PROTEIN-TYROSINEKINASE 6) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267VAL A 275ALA A 288ILE A 332THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.78A | 5h2uB-1opkA:29.5 | 5h2uB-1opkA:25.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5H2U_C_1N1C501_1 (PROTEIN-TYROSINEKINASE 6) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | LEU A 267ALA A 288ILE A 332THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.75A | 5h2uC-1opkA:29.3 | 5h2uC-1opkA:25.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HES_A_032A401_1 (MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE MLT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 12 | GLY A 268VAL A 275ALA A 288ILE A 332THR A 334 | P16 A 2 ( 4.3A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.1A)P16 A 2 (-3.7A) | 0.69A | 5hesA-1opkA:10.6 | 5hesA-1opkA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HES_B_032B401_1 (MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE MLT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | GLY A 268ALA A 288LYS A 290ILE A 332THR A 334ASP A 344 | P16 A 2 ( 4.3A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)None | 1.00A | 5hesB-1opkA:27.3 | 5hesB-1opkA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HES_B_032B401_1 (MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE MLT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | GLY A 268VAL A 275ALA A 288LYS A 290ILE A 332THR A 334 | P16 A 2 ( 4.3A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.1A)P16 A 2 (-3.7A) | 0.67A | 5hesB-1opkA:27.3 | 5hesB-1opkA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HES_B_032B401_1 (MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE MLT) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | GLY A 269VAL A 275ALA A 288LYS A 290ILE A 332THR A 334 | NoneP16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.1A)P16 A 2 (-3.7A) | 0.76A | 5hesB-1opkA:27.3 | 5hesB-1opkA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HI2_A_BAXA801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | ALA A 288LYS A 290GLU A 305THR A 334LEU A 373HIS A 380 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)NoneNone | 0.55A | 5hi2A-1opkA:26.4 | 5hi2A-1opkA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HIE_A_P06A801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 12 | VAL A 275ALA A 288LYS A 290ILE A 332THR A 334 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.1A)P16 A 2 (-3.7A) | 0.40A | 5hieA-1opkA:25.4 | 5hieA-1opkA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HIE_B_P06B801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 12 | VAL A 275ALA A 288LYS A 290ILE A 332THR A 334 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.1A)P16 A 2 (-3.7A) | 0.40A | 5hieB-1opkA:25.4 | 5hieB-1opkA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5HIE_D_P06D801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 12 | VAL A 275ALA A 288LYS A 290ILE A 332THR A 334 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.1A)P16 A 2 (-3.7A) | 0.40A | 5hieD-1opkA:25.5 | 5hieD-1opkA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5I9X_A_DB8A1001_1 (EPHRIN TYPE-ARECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | ALA A 288LYS A 290ILE A 332THR A 334GLY A 340GLU A 348LEU A 389 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-4.4A) | 0.74A | 5i9xA-1opkA:31.6 | 5i9xA-1opkA:25.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5I9Y_A_1N1A1001_1 (EPHRIN TYPE-ARECEPTOR 2) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | ALA A 288LYS A 290MET A 309THR A 334GLY A 340GLU A 348LEU A 389 | P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)NoneP16 A 2 (-4.4A) | 0.83A | 5i9yA-1opkA:31.0 | 5i9yA-1opkA:25.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5MO4_A_NILA601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 10 | LEU A 267TYR A 272VAL A 275GLU A 305ILE A 332MET A 337GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-4.1A)NoneP16 A 2 (-3.4A) | 0.74A | 5mo4A-1opkA:54.2 | 5mo4A-1opkA:98.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5MO4_A_NILA601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 10 | LEU A 267VAL A 275LYS A 290GLU A 305ILE A 332PHE A 336MET A 337GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-4.1A)P16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A) | 0.58A | 5mo4A-1opkA:54.2 | 5mo4A-1opkA:98.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5MO4_A_NILA601_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | ALA A 288VAL A 308MET A 309ILE A 312LEU A 317HIS A 380LEU A 389 | P16 A 2 (-3.4A)NoneP16 A 2 (-3.3A)NoneNoneNoneP16 A 2 (-4.4A) | 0.62A | 5mo4A-1opkA:54.2 | 5mo4A-1opkA:98.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5MO4_A_NILA601_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | ALA A 288VAL A 308MET A 309LEU A 317HIS A 380LEU A 389ALA A 399 | P16 A 2 (-3.4A)NoneP16 A 2 (-3.3A)NoneNoneP16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.59A | 5mo4A-1opkA:54.2 | 5mo4A-1opkA:98.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5MO4_A_NILA601_2 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | ALA A 288VAL A 308MET A 309LEU A 317VAL A 318HIS A 380LEU A 389 | P16 A 2 (-3.4A)NoneP16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)NoneP16 A 2 (-4.4A) | 0.58A | 5mo4A-1opkA:54.2 | 5mo4A-1opkA:98.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5P9I_A_1E8A701_1 (TYROSINE-PROTEINKINASE BTK) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | GLY A 273VAL A 275ALA A 288LYS A 290ILE A 332THR A 334 | NoneP16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.1A)P16 A 2 (-3.7A) | 0.83A | 5p9iA-1opkA:30.0 | 5p9iA-1opkA:28.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5TE0_A_XINA401_1 (AP2-ASSOCIATEDPROTEIN KINASE 1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | ALA A 288GLU A 305MET A 309VAL A 318PHE A 336GLY A 340LEU A 389 | P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 ( 4.4A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.43A | 5te0A-1opkA:23.3 | 5te0A-1opkA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VCV_A_1N1A404_1 (MEMBRANE-ASSOCIATEDTYROSINE- ANDTHREONINE-SPECIFICCDC2-INHIBITORYKINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305VAL A 318GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 ( 4.7A)P16 A 2 (-3.4A) | 1.07A | 5vcvA-1opkA:22.9 | 5vcvA-1opkA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VCV_A_1N1A404_1 (MEMBRANE-ASSOCIATEDTYROSINE- ANDTHREONINE-SPECIFICCDC2-INHIBITORYKINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | LEU A 267ALA A 288LYS A 290GLU A 305VAL A 318THR A 334 | P16 A 2 ( 4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 ( 4.7A)P16 A 2 (-3.7A) | 0.51A | 5vcvA-1opkA:22.9 | 5vcvA-1opkA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VCY_A_DB8A401_1 (MEMBRANE-ASSOCIATEDTYROSINE- ANDTHREONINE-SPECIFICCDC2-INHIBITORYKINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 6 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305THR A 334 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A) | 0.59A | 5vcyA-1opkA:22.8 | 5vcyA-1opkA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATEDKINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.65A | 5y7zA-1opkA:22.7 | 5y7zA-1opkA:10.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATEDKINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.65A | 5y7zA-1opkA:22.7 | 5y7zA-1opkA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y80_A_IREA401_0 (CYCLIN-G-ASSOCIATEDKINASE) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305THR A 334GLY A 340LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.7A)P16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.51A | 5y80A-1opkA:22.8 | 5y80A-1opkA:10.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZV2_A_LEVA801_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 8 / 12 | LEU A 267GLY A 268VAL A 275ALA A 288GLU A 305MET A 309GLY A 340ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 ( 4.3A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.4A)P16 A 2 (-3.5A) | 0.50A | 5zv2A-1opkA:31.5 | 5zv2A-1opkA:10.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZV2_B_LEVB801_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | LEU A 267GLY A 268VAL A 275ALA A 288LYS A 290GLU A 305MET A 309GLY A 340ALA A 399 | P16 A 2 ( 4.2A)P16 A 2 ( 4.3A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.4A)P16 A 2 (-3.5A) | 0.50A | 5zv2B-1opkA:31.3 | 5zv2B-1opkA:10.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6BQG_A_ERMA1201_1 (5-HYDROXYTRYPTAMINERECEPTOR 2C,SOLUBLECYTOCHROME B562) |
4crm | TRANSLATIONINITIATION FACTORRLI1 (Saccharomycescerevisiae) | 5 / 12 | SER P 249VAL P 524GLY P 224ASN P 387VAL P 254 | NoneNoneNoneADP P1612 (-3.6A)None | 1.10A | 6bqgA-4crmP:undetectable | 6bqgA-4crmP:9.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6BSD_A_1N1A901_0 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 9 / 12 | VAL A 275ALA A 288LYS A 290GLU A 305MET A 309THR A 334MET A 337GLY A 340LEU A 389 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.53A | 6bsdA-1opkA:29.6 | 6bsdA-1opkA:11.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6F3N_B_ADNB505_2 (-) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 4 | GLN A 319THR A 334HIS A 380LEU A 403 | NoneP16 A 2 (-3.7A)NoneNone | 1.28A | 6f3nB-1opkA:undetectable | 6f3nB-1opkA:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6FNM_A_1N1A1001_1 (-) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | VAL A 275ALA A 288ILE A 332THR A 334MET A 337GLY A 340LEU A 389 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)NoneP16 A 2 (-3.4A)P16 A 2 (-4.4A) | 0.72A | 6fnmA-1opkA:32.3 | 6fnmA-1opkA:27.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6FNM_A_1N1A1001_1 (-) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 7 / 12 | VAL A 275ALA A 288LYS A 290GLU A 305ILE A 332THR A 334MET A 337 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)None | 0.81A | 6fnmA-1opkA:32.3 | 6fnmA-1opkA:27.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6GBN_A_ADNA501_2 (-) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 5 | GLN A 319THR A 334HIS A 380LEU A 403 | NoneP16 A 2 (-3.7A)NoneNone | 1.29A | 6gbnA-1opkA:undetectable | 6gbnA-1opkA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6GBN_D_ADND501_2 (-) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 5 | GLN A 319THR A 334HIS A 380LEU A 403 | NoneP16 A 2 (-3.7A)NoneNone | 1.28A | 6gbnD-1opkA:undetectable | 6gbnD-1opkA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_A_STIA604_0 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | VAL A 275ALA A 288LYS A 290GLU A 305MET A 309ILE A 312VAL A 318ILE A 332THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.70A | 6hd4A-1opkA:36.8 | 6hd4A-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_A_STIA604_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 5 | TYR A 272VAL A 308MET A 337GLY A 340 | P16 A 2 (-3.6A)NoneNoneP16 A 2 (-3.4A) | 0.76A | 6hd4A-1opkA:36.8 | 6hd4A-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_A_STIA604_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 5 | VAL A 308PHE A 336MET A 337GLY A 340 | NoneP16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A) | 0.47A | 6hd4A-1opkA:36.8 | 6hd4A-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_B_STIB602_0 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288GLU A 305MET A 309ILE A 312VAL A 318ILE A 332THR A 334LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.64A | 6hd4B-1opkA:36.9 | 6hd4B-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_B_STIB602_0 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | VAL A 275ALA A 288LYS A 290GLU A 305MET A 309ILE A 312VAL A 318ILE A 332THR A 334ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 (-3.5A) | 0.70A | 6hd4B-1opkA:36.9 | 6hd4B-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_B_STIB602_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267TYR A 272VAL A 308MET A 337GLY A 340 | P16 A 2 ( 4.2A)P16 A 2 (-3.6A)NoneNoneP16 A 2 (-3.4A) | 0.84A | 6hd4B-1opkA:36.9 | 6hd4B-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_B_STIB602_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 6 | LEU A 267VAL A 308PHE A 336MET A 337GLY A 340 | P16 A 2 ( 4.2A)NoneP16 A 2 ( 4.4A)NoneP16 A 2 (-3.4A) | 0.56A | 6hd4B-1opkA:36.9 | 6hd4B-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD6_A_STIA603_0 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 11 / 12 | VAL A 275ALA A 288LYS A 290GLU A 305MET A 309VAL A 318ILE A 332THR A 334PHE A 336LEU A 389ALA A 399 | P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)P16 A 2 ( 4.7A)P16 A 2 (-4.1A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A)P16 A 2 (-3.5A) | 0.63A | 6hd6A-1opkA:36.7 | 6hd6A-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD6_A_STIA603_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 4 / 5 | LEU A 267ILE A 312MET A 337GLY A 340 | P16 A 2 ( 4.2A)NoneNoneP16 A 2 (-3.4A) | 0.86A | 6hd6A-1opkA:36.7 | 6hd6A-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD6_B_STIB601_0 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288GLU A 305MET A 309ILE A 312VAL A 318THR A 334PHE A 336LEU A 389 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A)P16 A 2 (-4.4A) | 0.68A | 6hd6B-1opkA:36.8 | 6hd6B-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD6_B_STIB601_0 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 10 / 12 | LEU A 267VAL A 275ALA A 288LYS A 290GLU A 305MET A 309ILE A 312VAL A 318THR A 334PHE A 336 | P16 A 2 ( 4.2A)P16 A 2 (-4.5A)P16 A 2 (-3.4A)P16 A 2 (-4.5A)P16 A 2 (-4.2A)P16 A 2 (-3.3A)NoneP16 A 2 ( 4.7A)P16 A 2 (-3.7A)P16 A 2 ( 4.4A) | 0.60A | 6hd6B-1opkA:36.8 | 6hd6B-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD6_B_STIB601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 7 | TYR A 272VAL A 308ILE A 332MET A 337GLY A 340 | P16 A 2 (-3.6A)NoneP16 A 2 (-4.1A)NoneP16 A 2 (-3.4A) | 0.75A | 6hd6B-1opkA:36.8 | 6hd6B-1opkA:28.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD6_B_STIB601_1 (TYROSINE-PROTEINKINASE ABL1) |
1opk | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Musmusculus) | 5 / 7 | VAL A 308ILE A 332MET A 337GLY A 340ALA A 399 | NoneP16 A 2 (-4.1A)NoneP16 A 2 (-3.4A)P16 A 2 (-3.5A) | 0.58A | 6hd6B-1opkA:36.8 | 6hd6B-1opkA:28.37 |