SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OZ2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZBP_A_SAMA300_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	3oz2	DIGERANYLGERANYLGLYC EROPHOSPHOLIPID REDUCTASE (Thermoplasma acidophilum)	5 / 12	GLY A 223 GLY A 208 GLY A 225 LEU A 201 LEU A 357	None OZ2 A 502 ( 3.9A) OZ2 A 502 ( 4.0A) None None	1.11A	2zbpA-3oz2A: undetectable	2zbpA-3oz2A: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZI9_A_CL9A401_2 (DEOXYCYTIDINE KINASE)	3oz2	DIGERANYLGERANYLGLYC EROPHOSPHOLIPID REDUCTASE (Thermoplasma acidophilum)	3 / 3	ASP A 198 PHE A 199 LEU A 201	None OZ2 A 502 ( 3.8A) None	0.73A	2zi9A-3oz2A: undetectable	2zi9A-3oz2A: 20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_B_MTXB164_1 (DIHYDROFOLATE REDUCTASE)	3oz2	DIGERANYLGERANYLGLYC EROPHOSPHOLIPID REDUCTASE (Thermoplasma acidophilum)	5 / 12	ILE A 83 ALA A 72 ILE A 291 ARG A 341 LEU A 378	None GOL A 515 ( 4.4A) OZ2 A 502 (-4.8A) None None	1.26A	3ia4B-3oz2A: undetectable	3ia4B-3oz2A: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QI9_C_MTXC201_1 (DIHYDROFOLATE REDUCTASE)	3oz2	DIGERANYLGERANYLGLYC EROPHOSPHOLIPID REDUCTASE (Thermoplasma acidophilum)	5 / 11	ILE A 83 ALA A 72 ILE A 291 ARG A 341 LEU A 378	None GOL A 515 ( 4.4A) OZ2 A 502 (-4.8A) None None	1.29A	4qi9C-3oz2A: undetectable	4qi9C-3oz2A: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J2T_C_VLBC503_2 (TUBULIN ALPHA-1B CHAIN)	4i7z	APOCYTOCHROME F (Mastigocladus laminosus)	5 / 12	LEU C 41 PRO C 252 VAL C 255 ILE C 259 ALA C 260	None None None None OZ2 C 303 ( 4.3A)	0.82A	5j2tC-4i7zC: undetectable	5j2tC-4i7zC: 18.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZBP_A_SAMA300_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","3oz2","DIGERANYLGERANYLGLYCEROPHOSPHOLIPID REDUCTASE","Thermoplasma acidophilum",5,"GLY A 223;GLY A 208;GLY A 225;LEU A 201;LEU A 357","None;OZ2 A 502 ( 3.9A);OZ2 A 502 ( 4.0A);None;None","1.11A","2zbpA-3oz2A:undetectable",null],["2ZI9_A_CL9A401_2","DEOXYCYTIDINE KINASE","3oz2","DIGERANYLGERANYLGLYCEROPHOSPHOLIPID REDUCTASE","Thermoplasma acidophilum",3,"ASP A 198;PHE A 199;LEU A 201","None;OZ2 A 502 ( 3.8A);None","0.73A","2zi9A-3oz2A:undetectable","2zbpA-3oz2A:21.59"],["3IA4_B_MTXB164_1","DIHYDROFOLATE REDUCTASE","3oz2","DIGERANYLGERANYLGLYCEROPHOSPHOLIPID REDUCTASE","Thermoplasma acidophilum",5,"ILE A  83;ALA A  72;ILE A 291;ARG A 341;LEU A 378","None;GOL A 515 ( 4.4A);OZ2 A 502 (-4.8A);None;None","1.26A","3ia4B-3oz2A:undetectable","2zi9A-3oz2A:20.85"],["4QI9_C_MTXC201_1","DIHYDROFOLATE REDUCTASE","3oz2","DIGERANYLGERANYLGLYCEROPHOSPHOLIPID REDUCTASE","Thermoplasma acidophilum",5,"ILE A  83;ALA A  72;ILE A 291;ARG A 341;LEU A 378","None;GOL A 515 ( 4.4A);OZ2 A 502 (-4.8A);None;None","1.29A","4qi9C-3oz2A:undetectable","3ia4B-3oz2A:19.17"],["5J2T_C_VLBC503_2","TUBULIN ALPHA-1B CHAIN","4i7z","APOCYTOCHROME F","Mastigocladus laminosus",5,"LEU C  41;PRO C 252;VAL C 255;ILE C 259;ALA C 260","None;None;None;None;OZ2 C 303 ( 4.3A)","0.82A","5j2tC-4i7zC:undetectable","4qi9C-3oz2A:17.86"]]