SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OYP'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1KIA_A_SAMA293_0 (GLYCINEN-METHYLTRANSFERASE) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 5 / 12 | ILE A 290GLY A 413ALA A 404TRP A 145GLY A 423 | NoneNoneOYP A 664 (-3.3A)NoneNone | 1.10A | 1kiaA-3rdeA:undetectable | 1kiaA-3rdeA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1KIA_B_SAMB1293_0 (GLYCINEN-METHYLTRANSFERASE) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 5 / 12 | ILE A 290GLY A 413ALA A 404TRP A 145GLY A 423 | NoneNoneOYP A 664 (-3.3A)NoneNone | 1.10A | 1kiaB-3rdeA:undetectable | 1kiaB-3rdeA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1KIA_C_SAMC2293_0 (GLYCINEN-METHYLTRANSFERASE) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 5 / 12 | ILE A 290GLY A 413ALA A 404TRP A 145GLY A 423 | NoneNoneOYP A 664 (-3.3A)NoneNone | 1.11A | 1kiaC-3rdeA:undetectable | 1kiaC-3rdeA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1NBH_B_SAMB1293_0 (GLYCINEN-METHYLTRANSFERASE) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 5 / 12 | ILE A 290GLY A 413ALA A 404TRP A 145GLY A 423 | NoneNoneOYP A 664 (-3.3A)NoneNone | 1.10A | 1nbhB-3rdeA:undetectable | 1nbhB-3rdeA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1NBI_B_SAMB1293_0 (GLYCINEN-METHYLTRANSFERASE) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 5 / 12 | ILE A 290GLY A 413ALA A 404TRP A 145GLY A 423 | NoneNoneOYP A 664 (-3.3A)NoneNone | 1.16A | 1nbiB-3rdeA:undetectable | 1nbiB-3rdeA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1S9P_B_DESB459_2 (ESTROGEN-RELATEDRECEPTOR GAMMA) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 3 / 3 | LEU A 408HIS A 366ILE A 400 | OYP A 664 (-3.7A)FE2 A 1 ( 3.4A)OYP A 664 ( 4.6A) | 0.55A | 1s9pB-3rdeA:undetectable | 1s9pB-3rdeA:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1Y93_A_HAEA301_1 (MACROPHAGEMETALLOELASTASE) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 4 / 6 | ILE A 593GLU A 357HIS A 361HIS A 545 | OYP A 664 (-4.3A)OYP A 664 (-3.6A)FE2 A 1 ( 3.4A)FE2 A 1 (-3.3A) | 0.87A | 1y93A-3rdeA:undetectable | 1y93A-3rdeA:15.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IJD_B_C2FB314_1 (UNCHARACTERIZEDPROTEIN) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 3 / 3 | THR A 237LYS A 189GLU A 357 | NoneNoneOYP A 664 (-3.6A) | 1.01A | 3ijdB-3rdeA:undetectable | 3ijdB-3rdeA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LJG_A_HAEA301_1 (MACROPHAGEMETALLOELASTASE) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 4 / 5 | ILE A 593GLU A 357HIS A 361HIS A 545 | OYP A 664 (-4.3A)OYP A 664 (-3.6A)FE2 A 1 ( 3.4A)FE2 A 1 (-3.3A) | 0.69A | 3ljgA-3rdeA:undetectable | 3ljgA-3rdeA:15.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3T3S_C_9PLC1_1 (CYTOCHROME P450 2A13) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 4 / 7 | PHE A 175ASN A 401ALA A 404LEU A 597 | OYP A 664 (-4.1A)NoneOYP A 664 (-3.3A)OYP A 664 ( 4.9A) | 0.90A | 3t3sC-3rdeA:undetectable | 3t3sC-3rdeA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5N5K_A_HAEA306_1 (MACROPHAGEMETALLOELASTASE) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 4 / 5 | ILE A 593GLU A 357HIS A 361HIS A 545 | OYP A 664 (-4.3A)OYP A 664 (-3.6A)FE2 A 1 ( 3.4A)FE2 A 1 (-3.3A) | 0.87A | 5n5kA-3rdeA:undetectable | 5n5kA-3rdeA:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5OM3_B_DXTB501_1 (ALPHA-1-ANTICHYMOTRYPSIN) |
3rde | ARACHIDONATE12-LIPOXYGENASE,12S-TYPE (Susscrofa) | 4 / 6 | LEU A 179SER A 178PHE A 175ASP A 174 | OYP A 664 (-3.3A)NoneOYP A 664 (-4.1A)None | 1.15A | 5om3A-3rdeA:undetectable5om3B-3rdeA:undetectable | 5om3A-3rdeA:11.235om3B-3rdeA:5.52 |