SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OXN'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB153_0 (ILEAL BILE ACID-BINDING PROTEIN)	1ikt	ESTRADIOL 17 BETA-DEHYDROGENASE 4 (Homo sapiens)	4 / 7	ILE A 44 PHE A 12 PHE A 79 GLY A 41	None None OXN A 123 ( 4.4A) None	0.70A	3em0B-1iktA: 0.1	3em0B-1iktA: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB153_0 (ILEAL BILE ACID-BINDING PROTEIN)	1ikt	ESTRADIOL 17 BETA-DEHYDROGENASE 4 (Homo sapiens)	4 / 7	ILE A 44 PHE A 12 PHE A 79 GLY A 42	None None OXN A 123 ( 4.4A) None	1.10A	3em0B-1iktA: 0.1	3em0B-1iktA: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_A_IL2A901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	1ikt	ESTRADIOL 17 BETA-DEHYDROGENASE 4 (Homo sapiens)	5 / 12	THR A 70 THR A 71 HIS A 37 LEU A 110 VAL A 30	None None None OXN A 123 ( 4.9A) None	1.14A	3sp9A-1iktA: undetectable	3sp9A-1iktA: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SP9_B_IL2B901_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR DELTA)	1ikt	ESTRADIOL 17 BETA-DEHYDROGENASE 4 (Homo sapiens)	5 / 12	THR A 70 THR A 71 HIS A 37 LEU A 110 VAL A 30	None None None OXN A 123 ( 4.9A) None	1.17A	3sp9B-1iktA: 0.0	3sp9B-1iktA: 18.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3EM0_B_CHDB153_0","ILEAL BILE ACID-BINDING PROTEIN","1ikt","ESTRADIOL 17 BETA-DEHYDROGENASE 4","Homo sapiens",4,"ILE A  44;PHE A  12;PHE A  79;GLY A  41","None;None;OXN A 123 ( 4.4A);None","0.70A","3em0B-1iktA:0.1",null],["3EM0_B_CHDB153_0","ILEAL BILE ACID-BINDING PROTEIN","1ikt","ESTRADIOL 17 BETA-DEHYDROGENASE 4","Homo sapiens",4,"ILE A  44;PHE A  12;PHE A  79;GLY A  42","None;None;OXN A 123 ( 4.4A);None","1.10A","3em0B-1iktA:0.1","3em0B-1iktA:23.45"],["3SP9_A_IL2A901_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA","1ikt","ESTRADIOL 17 BETA-DEHYDROGENASE 4","Homo sapiens",5,"THR A  70;THR A  71;HIS A  37;LEU A 110;VAL A  30","None;None;None;OXN A 123 ( 4.9A);None","1.14A","3sp9A-1iktA:undetectable","3em0B-1iktA:23.45"],["3SP9_B_IL2B901_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA","1ikt","ESTRADIOL 17 BETA-DEHYDROGENASE 4","Homo sapiens",5,"THR A  70;THR A  71;HIS A  37;LEU A 110;VAL A  30","None;None;None;OXN A 123 ( 4.9A);None","1.17A","3sp9B-1iktA:0.0","3sp9A-1iktA:18.65"]]