SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OPY'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 3n0t DIPEPTIDYL PEPTIDASE
2
(Homo
sapiens) 		5 / 11 TRP A 420
TYR A 163
GLY A 161
VAL A 192
PRO A 188
 OPY  A1001 (-3.5A)
None
None
None
OPY  A1001 (-4.3A)
 1.33A 1i9jH-3n0tA:
undetectable
1i9jL-3n0tA:
undetectable		 1i9jH-3n0tA:
18.70
1i9jL-3n0tA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGZ_D_COCD401_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3n0t DIPEPTIDYL PEPTIDASE
2
(Homo
sapiens) 		4 / 6 TYR A 110
TRP A 347
TYR A 163
ILE A 355
 None
OPY  A1001 (-4.1A)
None
None
 1.49A 2pgzD-3n0tA:
undetectable
2pgzE-3n0tA:
undetectable		 2pgzD-3n0tA:
20.25
2pgzE-3n0tA:
20.25