SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OPC'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_A_CHDA4_0 (FERROCHELATASE, MITOCHONDRIAL)	2zt9	CYTOCHROME B6 CYTOCHROME B6-F COMPLEX SUBUNIT 4 CYTOCHROME B6-F COMPLEX SUBUNIT 5 (Nostoc sp. PCC 7120; Nostoc sp. PCC 7120; Nostoc sp. PCC 7120)	5 / 9	MET A 96 LEU G 13 SER A 89 VAL B 43 GLY B 46	OPC H 30 ( 3.9A) BCR G 101 ( 4.0A) None BCR G 101 ( 3.9A) BCR G 101 ( 4.7A)	1.41A	3hcoA-2zt9A: undetectable	3hcoA-2zt9A: 19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_B_CHDB924_0 (FERROCHELATASE, MITOCHONDRIAL)	2zt9	CYTOCHROME B6 CYTOCHROME B6-F COMPLEX SUBUNIT 4 CYTOCHROME B6-F COMPLEX SUBUNIT 5 (Nostoc sp. PCC 7120; Nostoc sp. PCC 7120; Nostoc sp. PCC 7120)	5 / 10	MET A 96 LEU G 13 SER A 89 VAL B 43 GLY B 46	OPC H 30 ( 3.9A) BCR G 101 ( 4.0A) None BCR G 101 ( 3.9A) BCR G 101 ( 4.7A)	1.42A	3hcoB-2zt9A: undetectable	3hcoB-2zt9A: 19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDV_A_AICA375_1 (BETA-PEPTIDYL AMINOPEPTIDASE)	2zt9	CYTOCHROME B6-F COMPLEX SUBUNIT 5 CYTOCHROME B6-F COMPLEX SUBUNIT 7 (Nostoc sp. PCC 7120)	5 / 11	GLY G 8 LEU F 10 SER F 12 LEU F 6 LEU F 5	None None OPC H 30 (-4.8A) None None	1.18A	3ndvA-2zt9G: undetectable 3ndvB-2zt9G: undetectable	3ndvA-2zt9G: 9.84 3ndvB-2zt9G: 9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDV_B_AICB376_1 (BETA-PEPTIDYL AMINOPEPTIDASE)	2zt9	CYTOCHROME B6-F COMPLEX SUBUNIT 5 CYTOCHROME B6-F COMPLEX SUBUNIT 7 (Nostoc sp. PCC 7120)	5 / 11	LEU F 6 LEU F 5 GLY G 8 LEU F 10 SER F 12	None None None None OPC H 30 (-4.8A)	1.15A	3ndvA-2zt9F: undetectable 3ndvB-2zt9F: undetectable	3ndvA-2zt9F: 7.78 3ndvB-2zt9F: 7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDV_C_AICC375_1 (BETA-PEPTIDYL AMINOPEPTIDASE)	2zt9	CYTOCHROME B6-F COMPLEX SUBUNIT 5 CYTOCHROME B6-F COMPLEX SUBUNIT 7 (Nostoc sp. PCC 7120)	5 / 11	GLY G 8 LEU F 10 SER F 12 LEU F 6 LEU F 5	None None OPC H 30 (-4.8A) None None	1.15A	3ndvC-2zt9G: undetectable 3ndvD-2zt9G: undetectable	3ndvC-2zt9G: 9.84 3ndvD-2zt9G: 9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDV_D_AICD374_1 (BETA-PEPTIDYL AMINOPEPTIDASE)	2zt9	CYTOCHROME B6-F COMPLEX SUBUNIT 5 CYTOCHROME B6-F COMPLEX SUBUNIT 7 (Nostoc sp. PCC 7120)	5 / 11	LEU F 6 LEU F 5 GLY G 8 LEU F 10 SER F 12	None None None None OPC H 30 (-4.8A)	1.16A	3ndvC-2zt9F: undetectable 3ndvD-2zt9F: undetectable	3ndvC-2zt9F: 7.78 3ndvD-2zt9F: 7.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3HCO_A_CHDA4_0","FERROCHELATASE, MITOCHONDRIAL","2zt9","CYTOCHROME B6;CYTOCHROME B6-F COMPLEX SUBUNIT 4;CYTOCHROME B6-F COMPLEX SUBUNIT 5","Nostoc sp. PCC 7120;Nostoc sp. PCC 7120;Nostoc sp. PCC 7120",5,"MET A  96;LEU G  13;SER A  89;VAL B  43;GLY B  46","OPC H  30 ( 3.9A);BCR G 101 ( 4.0A);None;BCR G 101 ( 3.9A);BCR G 101 ( 4.7A)","1.41A","3hcoA-2zt9A:undetectable",null],["3HCO_B_CHDB924_0","FERROCHELATASE, MITOCHONDRIAL","2zt9","CYTOCHROME B6;CYTOCHROME B6-F COMPLEX SUBUNIT 4;CYTOCHROME B6-F COMPLEX SUBUNIT 5","Nostoc sp. PCC 7120;Nostoc sp. PCC 7120;Nostoc sp. PCC 7120",5,"MET A  96;LEU G  13;SER A  89;VAL B  43;GLY B  46","OPC H  30 ( 3.9A);BCR G 101 ( 4.0A);None;BCR G 101 ( 3.9A);BCR G 101 ( 4.7A)","1.42A","3hcoB-2zt9A:undetectable","3hcoA-2zt9A:19.89"],["3NDV_A_AICA375_1","BETA-PEPTIDYL AMINOPEPTIDASE;BETA-PEPTIDYL AMINOPEPTIDASE","2zt9","CYTOCHROME B6-F COMPLEX SUBUNIT 5;CYTOCHROME B6-F COMPLEX SUBUNIT 7","Nostoc sp. PCC 7120",5,"GLY G   8;LEU F  10;SER F  12;LEU F   6;LEU F   5","None;None;OPC H  30 (-4.8A);None;None","1.18A","3ndvA-2zt9G:undetectable;3ndvB-2zt9G:undetectable","3hcoB-2zt9A:19.89"],["3NDV_B_AICB376_1","BETA-PEPTIDYL AMINOPEPTIDASE;BETA-PEPTIDYL AMINOPEPTIDASE","2zt9","CYTOCHROME B6-F COMPLEX SUBUNIT 5;CYTOCHROME B6-F COMPLEX SUBUNIT 7","Nostoc sp. PCC 7120",5,"LEU F   6;LEU F   5;GLY G   8;LEU F  10;SER F  12","None;None;None;None;OPC H  30 (-4.8A)","1.15A","3ndvA-2zt9F:undetectable;3ndvB-2zt9F:undetectable","3ndvA-2zt9G:9.84;3ndvB-2zt9G:9.84"],["3NDV_C_AICC375_1","BETA-PEPTIDYL AMINOPEPTIDASE;BETA-PEPTIDYL AMINOPEPTIDASE","2zt9","CYTOCHROME B6-F COMPLEX SUBUNIT 5;CYTOCHROME B6-F COMPLEX SUBUNIT 7","Nostoc sp. PCC 7120",5,"GLY G   8;LEU F  10;SER F  12;LEU F   6;LEU F   5","None;None;OPC H  30 (-4.8A);None;None","1.15A","3ndvC-2zt9G:undetectable;3ndvD-2zt9G:undetectable","3ndvA-2zt9F:7.78;3ndvB-2zt9F:7.78"],["3NDV_D_AICD374_1","BETA-PEPTIDYL AMINOPEPTIDASE;BETA-PEPTIDYL AMINOPEPTIDASE","2zt9","CYTOCHROME B6-F COMPLEX SUBUNIT 5;CYTOCHROME B6-F COMPLEX SUBUNIT 7","Nostoc sp. PCC 7120",5,"LEU F   6;LEU F   5;GLY G   8;LEU F  10;SER F  12","None;None;None;None;OPC H  30 (-4.8A)","1.16A","3ndvC-2zt9F:undetectable;3ndvD-2zt9F:undetectable","3ndvC-2zt9G:9.84;3ndvD-2zt9G:9.84"]]