SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OOG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 147
HIS A 125
SER A 132
ARG A 142
GLY A  84
 None
None
None
OOG  A1305 ( 4.8A)
None
 1.14A 1jffB-4ur8A:
undetectable		 1jffB-4ur8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 GLY A  55
GLY A  53
SER A 212
LEU A  48
LEU A 189
 None
OOG  A1305 (-3.1A)
None
None
None
 0.99A 1ya4C-4ur8A:
undetectable		 1ya4C-4ur8A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 6 SER A 169
ALA A 170
SER A 173
ASN A 216
 OOG  A 401 (-3.0A)
OOG  A 401 ( 4.8A)
OOG  A 401 (-4.6A)
OOG  A 401 (-3.1A)
 1.10A 1yvpB-5oeiA:
undetectable		 1yvpB-5oeiA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 147
HIS A 125
SER A 132
ARG A 142
GLY A  84
 None
None
None
OOG  A1305 ( 4.8A)
None
 1.13A 2hxfB-4ur8A:
undetectable		 2hxfB-4ur8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 147
HIS A 125
SER A 132
ARG A 142
GLY A  84
 None
None
None
OOG  A1305 ( 4.8A)
None
 1.13A 2hxhB-4ur8A:
undetectable		 2hxhB-4ur8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 147
HIS A 125
SER A 132
ARG A 142
GLY A  84
 None
None
None
OOG  A1305 ( 4.8A)
None
 1.13A 2p4nB-4ur8A:
undetectable		 2p4nB-4ur8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		4 / 6 GLY A 190
GLY A 164
PHE A  49
PHE A  17
 None
None
None
OOG  A1305 (-4.0A)
 1.00A 2qx6A-4ur8A:
undetectable
2qx6B-4ur8A:
undetectable		 2qx6A-4ur8A:
22.15
2qx6B-4ur8A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 147
HIS A 125
SER A 132
ARG A 142
GLY A  84
 None
None
None
OOG  A1305 ( 4.8A)
None
 1.13A 2wbeB-4ur8A:
undetectable		 2wbeB-4ur8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 147
HIS A 125
SER A 132
ARG A 142
GLY A  84
 None
None
None
OOG  A1305 ( 4.8A)
None
 1.13A 3dcoB-4ur8A:
undetectable		 3dcoB-4ur8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 147
HIS A 125
SER A 132
ARG A 142
GLY A  84
 None
None
None
OOG  A1305 ( 4.8A)
None
 1.14A 3edlB-4ur8A:
undetectable		 3edlB-4ur8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 147
HIS A 125
SER A 132
ARG A 142
GLY A  84
 None
None
None
OOG  A1305 ( 4.8A)
None
 1.14A 3iz0B-4ur8A:
undetectable		 3iz0B-4ur8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 8 PHE A  48
THR A  53
GLY A 103
PHE A 263
 OOG  A 401 (-4.0A)
None
None
None
 0.79A 3tzfB-5oeiA:
undetectable		 3tzfB-5oeiA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 5 THR A  53
THR A  54
THR A 110
ASN A 137
 None
OOG  A 401 (-3.6A)
None
OOG  A 401 ( 4.8A)
 1.22A 4pgfB-5oeiA:
undetectable		 4pgfB-5oeiA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		5 / 10 SER A 198
SER A 169
LEU A  57
SER A 173
TRP A 262
 OOG  A 401 (-3.1A)
OOG  A 401 (-3.0A)
None
OOG  A 401 (-4.6A)
None
 1.19A 4yiaA-5oeiA:
undetectable		 4yiaA-5oeiA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 ALA A 195
PRO A 193
GLY A 191
GLY A 168
LEU A  15
 None
OOG  A1305 ( 4.7A)
OOG  A1305 (-4.5A)
None
None
 1.05A 5c0oH-4ur8A:
undetectable		 5c0oH-4ur8A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 5 ILE A 107
PHE A  48
SER A  82
ALA A  86
 None
OOG  A 401 (-4.0A)
None
None
 1.19A 5msdA-5oeiA:
undetectable		 5msdA-5oeiA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 147
HIS A 125
SER A 132
ARG A 142
GLY A  84
 None
None
None
OOG  A1305 ( 4.8A)
None
 1.14A 5ogcB-4ur8A:
undetectable		 5ogcB-4ur8A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM7_A_ACTA603_0
(SALICYLATE-AMP
LIGASE)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		4 / 4 THR A 174
THR A 259
ALA A 260
ARG A 321
 OOG  A 401 (-3.1A)
None
None
GOL  A 407 (-4.4A)
 1.50A 5wm7A-5oeiA:
3.3		 5wm7A-5oeiA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		5 / 9 ALA A 219
SER A 220
GLY A  52
SER A 169
GLY A 197
 None
None
OOG  A 401 (-3.6A)
OOG  A 401 (-3.0A)
OOG  A 401 ( 3.8A)
 0.94A 6bklE-5oeiA:
undetectable
6bklF-5oeiA:
undetectable
6bklG-5oeiA:
undetectable
6bklH-5oeiA:
undetectable		 6bklE-5oeiA:
10.09
6bklF-5oeiA:
10.09
6bklG-5oeiA:
10.09
6bklH-5oeiA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 4ur8 KETO-DEOXY-D-GALACTA
RATE DEHYDRATASE
(Agrobacterium
tumefaciens) 		5 / 10 LEU A  15
SER A 211
PHE A  49
GLY A 164
GLY A 168
 None
OOG  A1305 ( 3.8A)
None
None
None
 1.18A 6eu9B-4ur8A:
undetectable		 6eu9B-4ur8A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 103
VAL A  45
THR A 174
GLY A 175
ASP A 215
 None
None
OOG  A 401 (-3.1A)
None
OOG  A 401 ( 4.7A)
 1.05A 6gngA-5oeiA:
2.1		 6gngA-5oeiA:
23.65