SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OMT'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1D4Y_A_TPVA501_2 (PROTEIN (HIV-1PROTEASE)) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 4 / 8 | ARG A 210ALA A 332GLY A 329ILE A 234 | OMT A2473 (-3.9A)NoneNoneNone | 0.68A | 1d4yB-2vdcA:undetectable | 1d4yB-2vdcA:6.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1KT7_A_RTLA184_0 (PLASMARETINOL-BINDINGPROTEIN) |
2f1k | PREPHENATEDEHYDROGENASE (Synechocystissp.PCC6803) | 5 / 11 | LEU A 155ALA A 115VAL A 154LEU A 19HIS A 112 | NoneOMT A 114 (-3.1A)OCS A 150 ( 3.9A)NoneOMT A 114 ( 3.9A) | 1.42A | 1kt7A-2f1kA:undetectable | 1kt7A-2f1kA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LF9_A_ACRA700_1 (GLUCOAMYLASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 12 | TYR A1295ASP A 986GLU A 978ASN A 231ARG A 31 | NoneNoneOMT A2473 ( 4.9A)OMT A2473 (-4.0A)None | 1.30A | 1lf9A-2vdcA:0.0 | 1lf9A-2vdcA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1LF9_B_ACRB701_1 (GLUCOAMYLASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 12 | TYR A1295ASP A 986GLU A 978ASN A 231ARG A 31 | NoneNoneOMT A2473 ( 4.9A)OMT A2473 (-4.0A)None | 1.24A | 1lf9B-2vdcA:0.0 | 1lf9B-2vdcA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1RJD_A_SAMA801_0 (CARBOXY METHYLTRANSFERASE FORPROTEIN PHOSPHATASE2A CATALYTIC SUBUNIT) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 12 | GLN A 187ALA A 33GLY A 43GLY A 41CYH A 1 | NoneNoneNoneNoneOMT A2473 (-3.8A) | 1.08A | 1rjdA-2vdcA:undetectable | 1rjdA-2vdcA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1RJD_B_SAMB802_0 (CARBOXY METHYLTRANSFERASE FORPROTEIN PHOSPHATASE2A CATALYTIC SUBUNIT) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 12 | GLN A 187ALA A 33GLY A 43GLY A 41CYH A 1 | NoneNoneNoneNoneOMT A2473 (-3.8A) | 1.07A | 1rjdB-2vdcA:undetectable | 1rjdB-2vdcA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1RJD_C_SAMC803_0 (CARBOXY METHYLTRANSFERASE FORPROTEIN PHOSPHATASE2A CATALYTIC SUBUNIT) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 12 | GLN A 187ALA A 33GLY A 43GLY A 41CYH A 1 | NoneNoneNoneNoneOMT A2473 (-3.8A) | 1.05A | 1rjdC-2vdcA:undetectable | 1rjdC-2vdcA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ULV_A_ACRA3000_1 (GLUCODEXTRANASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 12 | TYR A1295ASP A 986GLU A 978ASN A 231ARG A 31 | NoneNoneOMT A2473 ( 4.9A)OMT A2473 (-4.0A)None | 1.12A | 1ulvA-2vdcA:0.0 | 1ulvA-2vdcA:23.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1VHW_A_ADNA252_1 (PURINE NUCLEOSIDEPHOSPHORYLASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 11 | ARG A 351GLY A 366VAL A 3GLU A 978HIS A 30 | NoneNoneNoneOMT A2473 ( 4.9A)None | 1.43A | 1vhwA-2vdcA:undetectable1vhwD-2vdcA:undetectable | 1vhwA-2vdcA:10.851vhwD-2vdcA:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1VHW_B_ADNB252_1 (PURINE NUCLEOSIDEPHOSPHORYLASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 9 | ARG A 351GLY A 366VAL A 3GLU A 978HIS A 30 | NoneNoneNoneOMT A2473 ( 4.9A)None | 1.44A | 1vhwB-2vdcA:undetectable1vhwF-2vdcA:undetectable | 1vhwB-2vdcA:10.851vhwF-2vdcA:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1VHW_C_ADNC252_1 (PURINE NUCLEOSIDEPHOSPHORYLASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 11 | ARG A 351GLY A 366VAL A 3GLU A 978HIS A 30 | NoneNoneNoneOMT A2473 ( 4.9A)None | 1.44A | 1vhwC-2vdcA:undetectable1vhwE-2vdcA:undetectable | 1vhwC-2vdcA:10.851vhwE-2vdcA:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1VHW_D_ADND252_1 (PURINE NUCLEOSIDEPHOSPHORYLASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 11 | HIS A 30ARG A 351GLY A 366VAL A 3GLU A 978 | NoneNoneNoneNoneOMT A2473 ( 4.9A) | 1.45A | 1vhwA-2vdcA:undetectable1vhwD-2vdcA:undetectable | 1vhwA-2vdcA:10.851vhwD-2vdcA:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1VHW_E_ADNE252_1 (PURINE NUCLEOSIDEPHOSPHORYLASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 11 | HIS A 30ARG A 351GLY A 366VAL A 3GLU A 978 | NoneNoneNoneNoneOMT A2473 ( 4.9A) | 1.43A | 1vhwC-2vdcA:undetectable1vhwE-2vdcA:undetectable | 1vhwC-2vdcA:10.851vhwE-2vdcA:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1VHW_F_ADNF252_1 (PURINE NUCLEOSIDEPHOSPHORYLASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 10 | HIS A 30ARG A 351GLY A 366VAL A 3GLU A 978 | NoneNoneNoneNoneOMT A2473 ( 4.9A) | 1.44A | 1vhwB-2vdcA:undetectable1vhwF-2vdcA:undetectable | 1vhwB-2vdcA:10.851vhwF-2vdcA:10.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2HMY_B_SAMB328_0 (PROTEIN(CYTOSINE-SPECIFICMETHYLTRANSFERASEHHAI)) |
4q22 | GLYCOSIDE HYDROLASEFAMILY 18 (Serratiaproteamaculans) | 5 / 12 | GLY A 113GLY A 115ILE A 82LEU A 84VAL A 35 | ACT A 502 ( 4.6A)GOL A 503 (-4.6A)NoneOMT A 89 ( 4.4A)None | 1.09A | 2hmyB-4q22A:undetectable | 2hmyB-4q22A:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PIV_A_T3A933_1 (ANDROGEN RECEPTOR) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 9 | ILE A 974GLY A1012TYR A 211GLU A 978ARG A 351 | NoneNoneNoneOMT A2473 ( 4.9A)None | 1.18A | 2pivA-2vdcA:0.0 | 2pivA-2vdcA:10.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PIW_A_T3A933_1 (ANDROGEN RECEPTOR) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 10 | ILE A 974GLY A1012TYR A 211GLU A 978ARG A 351 | NoneNoneNoneOMT A2473 ( 4.9A)None | 1.28A | 2piwA-2vdcA:undetectable | 2piwA-2vdcA:10.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3EL9_A_DR7A100_1 (PROTEASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 4 / 8 | ARG A 210ALA A 332GLY A 329ILE A 234 | OMT A2473 (-3.9A)NoneNoneNone | 0.66A | 3el9A-2vdcA:undetectable | 3el9A-2vdcA:5.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NNE_G_ACTG601_0 (CHOLINE OXIDASE) |
2f1k | PREPHENATEDEHYDROGENASE (Synechocystissp.PCC6803) | 4 / 6 | ALA A 236HIS A 179VAL A 174HIS A 170 | NoneNoneOMT A 114 ( 4.7A)None | 1.21A | 3nneG-2f1kA:undetectable | 3nneG-2f1kA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3SPK_A_TPVA100_2 (HIV-1 PROTEASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 4 / 7 | ARG A 210ALA A 332GLY A 329ILE A 234 | OMT A2473 (-3.9A)NoneNoneNone | 0.71A | 3spkB-2vdcA:undetectable | 3spkB-2vdcA:5.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3TM4_A_SAMA401_0 (TRNA (GUANINEN2-)-METHYLTRANSFERASE TRM14) |
2f1k | PREPHENATEDEHYDROGENASE (Synechocystissp.PCC6803) | 5 / 12 | LEU A 164GLY A 111HIS A 112ALA A 101PRO A 167 | NoneNoneOMT A 114 ( 3.9A)NoneNone | 1.29A | 3tm4A-2f1kA:6.7 | 3tm4A-2f1kA:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3TM4_B_SAMB401_0 (TRNA (GUANINEN2-)-METHYLTRANSFERASE TRM14) |
2f1k | PREPHENATEDEHYDROGENASE (Synechocystissp.PCC6803) | 5 / 12 | LEU A 164GLY A 111HIS A 112ALA A 101PRO A 167 | NoneNoneOMT A 114 ( 3.9A)NoneNone | 1.32A | 3tm4B-2f1kA:6.7 | 3tm4B-2f1kA:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4DJF_B_C2FB300_0 (5-METHYLTETRAHYDROFOLATE CORRINOID/IRONSULFUR PROTEINMETHYLTRANSFERASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 12 | ILE A1021LEU A1000GLY A1012SER A 212ARG A 210 | NoneNoneNoneNoneOMT A2473 (-3.9A) | 1.13A | 4djfB-2vdcA:8.6 | 4djfB-2vdcA:10.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4JVL_A_ESTA702_1 (ESTROGENSULFOTRANSFERASE) |
2isa | CATALASE (Aliivibriosalmonicida) | 4 / 9 | TYR A 337LYS A 54HIS A 54PHE A 140 | HEM A 486 (-4.1A)OMT A 53 (-3.0A)HEM A 486 (-3.4A)HEM A 486 (-3.4A) | 1.35A | 4jvlA-2isaA:undetectable | 4jvlA-2isaA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5M8R_C_MMSC516_1 (5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 4 / 8 | HIS A 208LEU A 228GLY A 275SER A 272 | NoneNoneNoneOMT A2473 ( 3.8A) | 0.91A | 5m8rC-2vdcA:undetectable | 5m8rC-2vdcA:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X7F_A_SAMA301_0 (PUTATIVEO-METHYLTRANSFERASERV1220C) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 12 | VAL A 372GLY A 4GLY A 365ALA A 229GLN A 223 | NoneNoneNoneNoneOMT A2473 (-4.3A) | 0.97A | 5x7fA-2vdcA:undetectable | 5x7fA-2vdcA:10.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X7F_A_SAMA301_0 (PUTATIVEO-METHYLTRANSFERASERV1220C) |
2vdc | GLUTAMATE SYNTHASE[NADPH] LARGE CHAIN (Azospirillumbrasilense) | 5 / 12 | VAL A 372GLY A 4GLY A 366ALA A 229GLN A 223 | NoneNoneNoneNoneOMT A2473 (-4.3A) | 0.72A | 5x7fA-2vdcA:undetectable | 5x7fA-2vdcA:10.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XDQ_C_CHDC308_0 (CYTOCHROME C OXIDASESUBUNIT 3CYTOCHROME C OXIDASESUBUNIT 7A1,MITOCHONDRIAL) |
5o84 | GLUTATHIONES-TRANSFERASE U23 (Arabidopsisthaliana) | 4 / 5 | PHE A 160PHE A 157LEU A 182PHE A 179 | OMT A 14 ( 3.8A)NoneNoneNone | 1.34A | 5xdqC-5o84A:undetectable5xdqJ-5o84A:undetectable | 5xdqC-5o84A:17.565xdqJ-5o84A:16.51 |