SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OMO'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWK_A_117A2_1 (HMG-COA REDUCTASE)	1p0z	SENSOR KINASE CITA (Klebsiella pneumoniae)	4 / 8	ARG A 107 SER A 105 VAL A 97 SER A 96	OMO A1631 ( 2.9A) None None None	1.20A	1hwkA-1p0zA: undetectable	1hwkA-1p0zA: 15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWK_C_117C4_1 (HMG-COA REDUCTASE)	1p0z	SENSOR KINASE CITA (Klebsiella pneumoniae)	4 / 8	ARG A 107 SER A 105 VAL A 97 SER A 96	OMO A1631 ( 2.9A) None None None	1.25A	1hwkC-1p0zA: undetectable	1hwkC-1p0zA: 15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KIA_B_SAMB1293_0 (GLYCINE N-METHYLTRANSFERASE)	1n60	CARBON MONOXIDE DEHYDROGENASE LARGE CHAIN (Oligotropha carboxidovorans)	5 / 12	ILE B 489 GLY B 354 VAL B 392 ALA B 99 GLY B 569	None None None None OMO B4921 ( 3.5A)	1.23A	1kiaB-1n60B: undetectable	1kiaB-1n60B: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RP8_C_ASCC501_1 (ASCORBATE-SPECIFIC PERMEASE IIC COMPONENT ULAA)	1p0z	SENSOR KINASE CITA (Klebsiella pneumoniae)	3 / 3	SER A 105 TYR A 56 ASP A 83	None FLC A1632 (-3.8A) OMO A1631 (-3.9A)	0.83A	4rp8C-1p0zA: 0.0	4rp8C-1p0zA: 12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XZK_A_AG2A700_1 (PUTATIVE NAD(+)--ARGININE ADP-RIBOSYLTRANSFERA SE VIS)	1n60	CARBON MONOXIDE DEHYDROGENASE LARGE CHAIN (Oligotropha carboxidovorans)	4 / 7	SER B 389 SER B 570 GLU B 488 GLU B 763	None MCN B4920 (-4.3A) None OMO B4921 ( 3.3A)	1.18A	4xzkA-1n60B: 0.0	4xzkA-1n60B: 15.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HWK_A_117A2_1","HMG-COA REDUCTASE","1p0z","SENSOR KINASE CITA","Klebsiella pneumoniae",4,"ARG A 107;SER A 105;VAL A  97;SER A  96","OMO A1631 ( 2.9A);None;None;None","1.20A","1hwkA-1p0zA:undetectable",null],["1HWK_C_117C4_1","HMG-COA REDUCTASE","1p0z","SENSOR KINASE CITA","Klebsiella pneumoniae",4,"ARG A 107;SER A 105;VAL A  97;SER A  96","OMO A1631 ( 2.9A);None;None;None","1.25A","1hwkC-1p0zA:undetectable","1hwkA-1p0zA:15.44"],["1KIA_B_SAMB1293_0","GLYCINE N-METHYLTRANSFERASE","1n60","CARBON MONOXIDE DEHYDROGENASE LARGE CHAIN","Oligotropha carboxidovorans",5,"ILE B 489;GLY B 354;VAL B 392;ALA B  99;GLY B 569","None;None;None;None;OMO B4921 ( 3.5A)","1.23A","1kiaB-1n60B:undetectable","1hwkC-1p0zA:15.44"],["4RP8_C_ASCC501_1","ASCORBATE-SPECIFIC PERMEASE IIC COMPONENT ULAA","1p0z","SENSOR KINASE CITA","Klebsiella pneumoniae",3,"SER A 105;TYR A  56;ASP A  83","None;FLC A1632 (-3.8A);OMO A1631 (-3.9A)","0.83A","4rp8C-1p0zA:0.0","1kiaB-1n60B:18.09"],["4XZK_A_AG2A700_1","PUTATIVE NAD(+)--ARGININE ADP-RIBOSYLTRANSFERASE VIS","1n60","CARBON MONOXIDE DEHYDROGENASE LARGE CHAIN","Oligotropha carboxidovorans",4,"SER B 389;SER B 570;GLU B 488;GLU B 763","None;MCN B4920 (-4.3A);None;OMO B4921 ( 3.3A)","1.18A","4xzkA-1n60B:0.0","4rp8C-1p0zA:12.82"]]