SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OMN'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1PXX_C_DIFC2701_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.04A | 1pxxC-1sezA:undetectable | 1pxxC-1sezA:21.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1WG8_A_SAMA3142_0 (PREDICTEDS-ADENOSYLMETHIONINE-DEPENDENTMETHYLTRANSFERASE) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | THR A 368GLY A 394GLY A 395GLY A 178SER A 335 | NoneNoneNoneOMN A 601 (-3.6A)None | 1.19A | 1wg8A-1sezA:3.0 | 1wg8A-1sezA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OAX_C_SNLC3001_1 (MINERALOCORTICOIDRECEPTOR) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | LEU A 334ALA A 174LEU A 184LEU A 473PHE A 392 | OMN A 601 (-4.7A)NoneNoneNoneOMN A 601 (-3.6A) | 1.48A | 2oaxC-1sezA:undetectable | 2oaxC-1sezA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CJT_C_SAMC302_0 (RIBOSOMAL PROTEINL11METHYLTRANSFERASE) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | LEU A 334GLY A 395LEU A 401ASP A 180LEU A 369 | OMN A 601 (-4.7A)NoneNoneNoneOMN A 601 (-3.7A) | 1.00A | 3cjtC-1sezA:3.9 | 3cjtC-1sezA:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LN1_A_CELA682_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.05A | 3ln1A-1sezA:undetectable | 3ln1A-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LN1_B_CELB682_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.05A | 3ln1B-1sezA:undetectable | 3ln1B-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LN1_C_CELC682_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.05A | 3ln1C-1sezA:undetectable | 3ln1C-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LN1_D_CELD682_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.05A | 3ln1D-1sezA:undetectable | 3ln1D-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LN1_D_CELD682_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 337SER A 335LEU A 409ALA A 438GLY A 370 | NoneNoneNoneFAD A 600 (-3.7A)OMN A 601 (-3.5A) | 0.98A | 3ln1D-1sezA:undetectable | 3ln1D-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NT1_A_NPSA5_1 (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.09A | 3nt1A-1sezA:0.0 | 3nt1A-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3NT1_B_NPSB4_1 (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.09A | 3nt1B-1sezA:0.0 | 3nt1B-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3PGH_D_FLPD701_1 (CYCLOOXYGENASE-2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.03A | 3pghD-1sezA:0.0 | 3pghD-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3RR3_A_FLRA700_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.06A | 3rr3A-1sezA:undetectable | 3rr3A-1sezA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4COX_A_IMNA701_1 (CYCLOOXYGENASE-2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.06A | 4coxA-1sezA:undetectable | 4coxA-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4COX_B_IMNB701_1 (CYCLOOXYGENASE-2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.07A | 4coxB-1sezA:undetectable | 4coxB-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4COX_C_IMNC701_1 (CYCLOOXYGENASE-2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.07A | 4coxC-1sezA:undetectable | 4coxC-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4COX_D_IMND701_1 (CYCLOOXYGENASE-2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.07A | 4coxD-1sezA:undetectable | 4coxD-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RRW_A_LURA705_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.06A | 4rrwA-1sezA:undetectable | 4rrwA-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RRZ_A_LURA705_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.06A | 4rrzA-1sezA:undetectable | 4rrzA-1sezA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5IKQ_A_JMSA602_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.06A | 5ikqA-1sezA:undetectable | 5ikqA-1sezA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5IKR_B_ID8B602_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.04A | 5ikrB-1sezA:0.0 | 5ikrB-1sezA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5JVZ_A_FLPA601_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.06A | 5jvzA-1sezA:0.0 | 5jvzA-1sezA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5KIR_A_RCXA601_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.06A | 5kirA-1sezA:undetectable | 5kirA-1sezA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5KIR_B_RCXB601_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | VAL A 332VAL A 173GLY A 175ALA A 174LEU A 369 | NoneNoneOMN A 601 (-3.6A)NoneOMN A 601 (-3.7A) | 1.08A | 5kirB-1sezA:undetectable | 5kirB-1sezA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5TL8_A_X2NA502_2 (PROTEIN CYP51) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 4 / 6 | PRO A 181LEU A 356PHE A 172LEU A 168 | NoneOMN A 601 ( 4.7A)TON A 603 (-3.9A)TON A 603 (-4.5A) | 1.21A | 5tl8A-1sezA:undetectable | 5tl8A-1sezA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5YBB_A_SAMA601_0 (TYPE IRESTRICTION-MODIFICATION SYSTEMMETHYLTRANSFERASESUBUNIT) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 12 | GLY A 175THR A 176CYH A 177GLY A 178LEU A 420 | OMN A 601 (-3.6A)NoneNoneOMN A 601 (-3.6A)None | 0.96A | 5ybbA-1sezA:undetectable | 5ybbA-1sezA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HU9_H_PCFH604_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 8CYTOCHROME C OXIDASEPOLYPEPTIDE 5A,MITOCHONDRIAL) |
1sez | PROTOPORPHYRINOGENOXIDASE,MITOCHONDRIAL (Nicotianatabacum) | 5 / 8 | GLY A 370PHE A 392VAL A 337GLY A 179ALA A 438 | OMN A 601 (-3.5A)OMN A 601 (-3.6A)NoneNoneFAD A 600 (-3.7A) | 1.43A | 6hu9H-1sezA:undetectable6hu9e-1sezA:undetectable | 6hu9H-1sezA:11.366hu9e-1sezA:14.97 |