SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OKA'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SOA_A_DB8A445_1 (CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA WITH A BETA 7 LINKER)	4wri	OKADAIC ACID BINDING PROTEIN 2-ALPHA (Halichondria okadai)	4 / 6	VAL A 18 MET A 15 VAL A 184 PHE A 100	None None OKA A 201 (-4.4A) None	1.03A	3soaA-4wriA: undetectable	3soaA-4wriA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QJQ_A_K1SA304_0 (ADP-SUGAR PYROPHOSPHATASE)	4wri	OKADAIC ACID BINDING PROTEIN 2-ALPHA (Halichondria okadai)	4 / 5	GLU A 25 TRP A 22 VAL A 36 LEU A 82	MLY A 47 ( 4.1A) OKA A 201 ( 4.7A) None None	1.31A	5qjqA-4wriA: undetectable 5qjqB-4wriA: undetectable	5qjqA-4wriA: 22.37 5qjqB-4wriA: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QJQ_B_K1SB304_0 (ADP-SUGAR PYROPHOSPHATASE)	4wri	OKADAIC ACID BINDING PROTEIN 2-ALPHA (Halichondria okadai)	4 / 5	TRP A 22 VAL A 36 LEU A 82 GLU A 25	OKA A 201 ( 4.7A) None None MLY A 47 ( 4.1A)	1.31A	5qjqA-4wriA: undetectable 5qjqB-4wriA: undetectable	5qjqA-4wriA: 22.37 5qjqB-4wriA: 22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QJQ_C_K1SC305_0 (ADP-SUGAR PYROPHOSPHATASE)	4wri	OKADAIC ACID BINDING PROTEIN 2-ALPHA (Halichondria okadai)	4 / 5	GLU A 25 TRP A 22 VAL A 36 LEU A 82	MLY A 47 ( 4.1A) OKA A 201 ( 4.7A) None None	1.33A	5qjqC-4wriA: undetectable 5qjqD-4wriA: undetectable	5qjqC-4wriA: 22.37 5qjqD-4wriA: 22.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3SOA_A_DB8A445_1","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II SUBUNIT ALPHA WITH A BETA 7 LINKER","4wri","OKADAIC ACID BINDING PROTEIN 2-ALPHA","Halichondria okadai",4,"VAL A  18;MET A  15;VAL A 184;PHE A 100","None;None;OKA A 201 (-4.4A);None","1.03A","3soaA-4wriA:undetectable",null],["5QJQ_A_K1SA304_0","ADP-SUGAR PYROPHOSPHATASE","4wri","OKADAIC ACID BINDING PROTEIN 2-ALPHA","Halichondria okadai",4,"GLU A  25;TRP A  22;VAL A  36;LEU A  82","MLY A  47 ( 4.1A);OKA A 201 ( 4.7A);None;None","1.31A","5qjqA-4wriA:undetectable;5qjqB-4wriA:undetectable","3soaA-4wriA:18.61"],["5QJQ_B_K1SB304_0","ADP-SUGAR PYROPHOSPHATASE","4wri","OKADAIC ACID BINDING PROTEIN 2-ALPHA","Halichondria okadai",4,"TRP A  22;VAL A  36;LEU A  82;GLU A  25","OKA A 201 ( 4.7A);None;None;MLY A  47 ( 4.1A)","1.31A","5qjqA-4wriA:undetectable;5qjqB-4wriA:undetectable","5qjqA-4wriA:22.37;5qjqB-4wriA:22.37"],["5QJQ_C_K1SC305_0","ADP-SUGAR PYROPHOSPHATASE","4wri","OKADAIC ACID BINDING PROTEIN 2-ALPHA","Halichondria okadai",4,"GLU A  25;TRP A  22;VAL A  36;LEU A  82","MLY A  47 ( 4.1A);OKA A 201 ( 4.7A);None;None","1.33A","5qjqC-4wriA:undetectable;5qjqD-4wriA:undetectable","5qjqA-4wriA:22.37;5qjqB-4wriA:22.37"]]