SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OHT'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 268
LEU A 271
MET A 306
ARG A 316
LEU A 345
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 (-4.3A)
 0.41A 1a28A-2gpvA:
25.9		 1a28A-2gpvA:
28.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 268
LEU A 271
MET A 306
ARG A 316
LEU A 345
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 (-4.3A)
 0.63A 1a28B-2gpvA:
25.7		 1a28B-2gpvA:
28.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.57A 1a52A-2gpvA:
27.9		 1a52A-2gpvA:
36.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.64A 1a52B-2gpvA:
27.5		 1a52B-2gpvA:
36.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 9 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.65A 1ereA-2gpvA:
26.4		 1ereA-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 9 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.64A 1ereB-2gpvA:
26.5		 1ereB-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 9 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.65A 1ereC-2gpvA:
26.5		 1ereC-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 9 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.67A 1ereD-2gpvA:
26.5		 1ereD-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 8 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.66A 1ereE-2gpvA:
26.5		 1ereE-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 8 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.65A 1ereF-2gpvA:
26.5		 1ereF-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA A 272
ASP A 273
GLU A 275
LEU A 276
TRP A 305
ARG A 316
 OHT  A 500 (-3.5A)
OHT  A 500 (-3.1A)
OHT  A 500 (-2.6A)
OHT  A 500 (-4.9A)
None
OHT  A 500 (-3.8A)
 0.70A 1errA-2gpvA:
26.4		 1errA-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 ALA A 272
GLU A 275
TRP A 305
LEU A 309
ARG A 316
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
None
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.52A 1errB-2gpvA:
26.0		 1errB-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 11 LEU A 268
LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.54A 1g50A-2gpvA:
26.8		 1g50A-2gpvA:
36.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 11 LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.70A 1g50A-2gpvA:
26.8		 1g50A-2gpvA:
36.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 268
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.65A 1g50B-2gpvA:
26.2		 1g50B-2gpvA:
36.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 11 LEU A 268
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.65A 1g50C-2gpvA:
26.5		 1g50C-2gpvA:
36.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		7 / 10 LEU A 268
LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.63A 1gwrA-2gpvA:
26.7		 1gwrA-2gpvA:
36.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GWR_B_ESTB600_1
(OESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 9 LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.57A 1gwrB-2gpvA:
26.7		 1gwrB-2gpvA:
36.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.66A 1pcgA-2gpvA:
26.4		 1pcgA-2gpvA:
37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.63A 1pcgB-2gpvA:
26.9		 1pcgB-2gpvA:
37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKN_A_RALA600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 268
ALA A 272
GLU A 275
MET A 306
LEU A 309
ARG A 316
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.41A 1qknA-2gpvA:
27.6		 1qknA-2gpvA:
33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		3 / 3 ASP A 273
LEU A 276
HIS A 434
 OHT  A 500 (-3.1A)
OHT  A 500 (-4.9A)
OHT  A 500 ( 4.7A)
 0.43A 1qknA-2gpvA:
27.6		 1qknA-2gpvA:
33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKT_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.74A 1qktA-2gpvA:
26.4		 1qktA-2gpvA:
37.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.61A 1qkuA-2gpvA:
26.6		 1qkuA-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.61A 1qkuB-2gpvA:
26.5		 1qkuB-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.63A 1qkuC-2gpvA:
26.6		 1qkuC-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		12 / 12 LEU A 265
LEU A 268
ALA A 272
GLU A 275
MET A 306
LEU A 309
VAL A 313
ARG A 316
TYR A 326
LEU A 345
HIS A 434
ILE A 438
 None
OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
None
OHT  A 500 (-3.8A)
OHT  A 500 (-4.5A)
OHT  A 500 (-4.3A)
OHT  A 500 ( 4.7A)
None
 0.59A 1s9pA-2gpvA:
34.7		 1s9pA-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 CYH A 269
LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
LEU A 342
PHE A 435
 OHT  A 500 ( 4.7A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
OHT  A 500 (-3.7A)
 1.12A 1s9pB-2gpvA:
34.6		 1s9pB-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 CYH A 269
LEU A 271
ALA A 272
GLU A 275
MET A 306
LEU A 309
ARG A 316
PHE A 435
 OHT  A 500 ( 4.7A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 (-3.7A)
 0.83A 1s9pB-2gpvA:
34.6		 1s9pB-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		11 / 12 LEU A 265
LEU A 271
ALA A 272
GLU A 275
MET A 306
LEU A 309
VAL A 313
ARG A 316
TYR A 326
LEU A 345
PHE A 435
 None
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
None
OHT  A 500 (-3.8A)
OHT  A 500 (-4.5A)
OHT  A 500 (-4.3A)
OHT  A 500 (-3.7A)
 0.58A 1s9pB-2gpvA:
34.6		 1s9pB-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		9 / 12 LEU A 271
ALA A 272
GLU A 275
LEU A 309
VAL A 313
ARG A 316
TYR A 326
LEU A 342
PHE A 435
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
None
OHT  A 500 (-3.8A)
OHT  A 500 (-4.5A)
OHT  A 500 ( 4.7A)
OHT  A 500 (-3.7A)
 1.21A 1s9pB-2gpvA:
34.6		 1s9pB-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		10 / 12 LEU A 265
LEU A 268
LEU A 271
ALA A 272
GLU A 275
MET A 306
LEU A 309
VAL A 313
ARG A 316
TYR A 326
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
None
OHT  A 500 (-3.8A)
OHT  A 500 (-4.5A)
 0.38A 1s9pC-2gpvA:
34.3		 1s9pC-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 LEU A 265
LEU A 268
MET A 306
LEU A 309
VAL A 313
ARG A 316
TYR A 326
ILE A 438
 None
OHT  A 500 (-4.1A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
None
OHT  A 500 (-3.8A)
OHT  A 500 (-4.5A)
None
 0.71A 1s9pC-2gpvA:
34.3		 1s9pC-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 LEU A 268
CYH A 269
LEU A 271
ALA A 272
GLU A 275
MET A 306
LEU A 309
ARG A 316
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.7A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.62A 1s9pC-2gpvA:
34.3		 1s9pC-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		11 / 12 LEU A 265
LEU A 268
ALA A 272
GLU A 275
MET A 306
LEU A 309
VAL A 313
ARG A 316
TYR A 326
LEU A 345
HIS A 434
 None
OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
None
OHT  A 500 (-3.8A)
OHT  A 500 (-4.5A)
OHT  A 500 (-4.3A)
OHT  A 500 ( 4.7A)
 0.48A 1s9pD-2gpvA:
33.7		 1s9pD-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		11 / 12 LEU A 265
LEU A 268
ALA A 272
MET A 306
LEU A 309
VAL A 313
ARG A 316
TYR A 326
LEU A 345
HIS A 434
ILE A 438
 None
OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
None
OHT  A 500 (-3.8A)
OHT  A 500 (-4.5A)
OHT  A 500 (-4.3A)
OHT  A 500 ( 4.7A)
None
 0.60A 1s9pD-2gpvA:
33.7		 1s9pD-2gpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 6 ASP A 273
LEU A 276
VAL A 277
ILE A 280
TRP A 305
TYR A 436
 OHT  A 500 (-3.1A)
OHT  A 500 (-4.9A)
None
None
None
None
 0.56A 1s9qA-2gpvA:
35.2		 1s9qA-2gpvA:
99.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 4 LEU A 276
VAL A 277
ILE A 280
TRP A 305
 OHT  A 500 (-4.9A)
None
None
None
 0.37A 1s9qB-2gpvA:
34.4		 1s9qB-2gpvA:
99.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 265
LEU A 268
LEU A 271
MET A 306
LEU A 345
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.9A)
OHT  A 500 (-4.3A)
 0.40A 1sqnA-2gpvA:
25.5		 1sqnA-2gpvA:
28.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 265
LEU A 268
LEU A 271
MET A 306
LEU A 345
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.9A)
OHT  A 500 (-4.3A)
 0.51A 1sqnB-2gpvA:
25.6		 1sqnB-2gpvA:
28.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 265
LEU A 271
ALA A 272
MET A 306
ARG A 316
 None
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.45A 1ya3A-2gpvA:
25.9		 1ya3A-2gpvA:
27.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 268
LEU A 271
ALA A 272
MET A 306
ARG A 316
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.54A 1ya3C-2gpvA:
25.0		 1ya3C-2gpvA:
27.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 268
LEU A 271
MET A 306
ARG A 316
LEU A 345
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 (-4.3A)
 0.77A 1zucB-2gpvA:
25.6		 1zucB-2gpvA:
28.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 265
LEU A 271
ALA A 272
MET A 306
ARG A 316
 None
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.47A 2aa5B-2gpvA:
25.6		 2aa5B-2gpvA:
26.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 268
LEU A 271
ALA A 272
MET A 306
ARG A 316
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.29A 2aa6A-2gpvA:
25.7		 2aa6A-2gpvA:
27.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 271
GLU A 275
MET A 306
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.48A 2j7xA-2gpvA:
26.8		 2j7xA-2gpvA:
33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA A 272
GLU A 275
LEU A 276
TRP A 305
LEU A 309
ARG A 316
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-4.9A)
None
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.61A 2jfaA-2gpvA:
27.0		 2jfaA-2gpvA:
32.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 ALA A 272
ASP A 273
GLU A 275
LEU A 276
TRP A 305
LEU A 309
ARG A 316
 OHT  A 500 (-3.5A)
OHT  A 500 (-3.1A)
OHT  A 500 (-2.6A)
OHT  A 500 (-4.9A)
None
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.60A 2jfaB-2gpvA:
26.2		 2jfaB-2gpvA:
32.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 5 LEU A 268
ALA A 272
TRP A 305
LEU A 309
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
None
OHT  A 500 ( 4.0A)
 0.71A 2oaxA-2gpvA:
26.0		 2oaxA-2gpvA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 265
LEU A 271
ALA A 272
MET A 306
ARG A 316
 None
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.32A 2oaxB-2gpvA:
25.6		 2oaxB-2gpvA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 271
LEU A 265
ALA A 264
LEU A 345
LEU A 324
 OHT  A 500 ( 4.4A)
None
None
OHT  A 500 (-4.3A)
None
 0.95A 2oaxB-2gpvA:
25.6		 2oaxB-2gpvA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 265
ALA A 272
TRP A 305
MET A 306
ARG A 316
 None
OHT  A 500 (-3.5A)
None
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.65A 2oaxC-2gpvA:
25.5		 2oaxC-2gpvA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 271
ALA A 272
TRP A 305
MET A 306
ARG A 316
 None
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
None
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.59A 2oaxD-2gpvA:
25.5		 2oaxD-2gpvA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 271
LEU A 265
ALA A 264
LEU A 345
LEU A 324
 OHT  A 500 ( 4.4A)
None
None
OHT  A 500 (-4.3A)
None
 0.88A 2oaxD-2gpvA:
25.5		 2oaxD-2gpvA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 265
LEU A 271
ALA A 272
MET A 306
ARG A 316
 None
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.46A 2oaxE-2gpvA:
25.3		 2oaxE-2gpvA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 271
LEU A 265
ALA A 264
LEU A 345
LEU A 324
 OHT  A 500 ( 4.4A)
None
None
OHT  A 500 (-4.3A)
None
 0.96A 2oaxE-2gpvA:
25.3		 2oaxE-2gpvA:
27.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 271
ALA A 272
TRP A 305
MET A 306
ARG A 316
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
None
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.46A 2oaxF-2gpvA:
25.6		 2oaxF-2gpvA:
27.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.76A 2ocfA-2gpvA:
27.4		 2ocfA-2gpvA:
31.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 6 ALA A 272
ASP A 273
GLU A 275
TRP A 305
ARG A 316
 OHT  A 500 (-3.5A)
OHT  A 500 (-3.1A)
OHT  A 500 (-2.6A)
None
OHT  A 500 (-3.8A)
 0.51A 2ouzA-2gpvA:
25.6		 2ouzA-2gpvA:
36.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 265
LEU A 271
TRP A 305
MET A 306
ARG A 316
 None
OHT  A 500 ( 4.4A)
None
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.83A 2q7jA-2gpvA:
26.0		 2q7jA-2gpvA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 268
LEU A 271
TRP A 305
MET A 306
ARG A 316
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
None
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.72A 2q7lA-2gpvA:
25.9		 2q7lA-2gpvA:
25.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA A 272
GLU A 275
LEU A 276
TRP A 305
LEU A 309
ARG A 316
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-4.9A)
None
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.67A 2qxsA-2gpvA:
26.0		 2qxsA-2gpvA:
36.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QXS_B_RALB600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA A 272
GLU A 275
LEU A 276
TRP A 305
LEU A 309
ARG A 316
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-4.9A)
None
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.69A 2qxsB-2gpvA:
25.8		 2qxsB-2gpvA:
36.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 271
TRP A 305
MET A 306
ARG A 316
LEU A 345
 None
OHT  A 500 ( 4.4A)
None
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 (-4.3A)
 0.74A 2w8yA-2gpvA:
25.7		 2w8yA-2gpvA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 268
LEU A 271
MET A 306
ARG A 316
LEU A 345
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 (-4.3A)
 0.48A 2w8yB-2gpvA:
25.8		 2w8yB-2gpvA:
28.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.54A 2yjaB-2gpvA:
26.8		 2yjaB-2gpvA:
36.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 342
LEU A 345
ALA A 431
VAL A 432
LEU A 301
 OHT  A 500 ( 4.7A)
OHT  A 500 (-4.3A)
OHT  A 500 (-4.3A)
None
None
 1.27A 3b0wA-2gpvA:
18.5		 3b0wA-2gpvA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 268
LEU A 271
MET A 306
ARG A 316
LEU A 345
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 (-4.3A)
 0.46A 3d90A-2gpvA:
25.4		 3d90A-2gpvA:
28.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 268
LEU A 271
MET A 306
ARG A 316
LEU A 345
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 (-4.3A)
 0.59A 3d90B-2gpvA:
25.4		 3d90B-2gpvA:
28.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.47A 3erdA-2gpvA:
26.6		 3erdA-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.44A 3erdB-2gpvA:
27.3		 3erdB-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.49A 3hm1A-2gpvA:
27.8		 3hm1A-2gpvA:
36.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 11 LEU A 268
LEU A 271
GLU A 275
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.52A 3hm1B-2gpvA:
27.5		 3hm1B-2gpvA:
36.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLL_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 268
LEU A 271
GLU A 275
MET A 306
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.57A 3ollA-2gpvA:
26.0		 3ollA-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLL_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 9 LEU A 268
LEU A 271
GLU A 275
MET A 306
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.58A 3ollB-2gpvA:
26.0		 3ollB-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		8 / 12 LEU A 268
LEU A 271
ALA A 272
GLU A 275
MET A 306
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.53A 3olsA-2gpvA:
27.8		 3olsA-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU A 268
ALA A 272
GLU A 275
MET A 306
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.57A 3olsB-2gpvA:
27.5		 3olsB-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.59A 3q95A-2gpvA:
27.4		 3q95A-2gpvA:
36.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU A 268
LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.57A 3q95B-2gpvA:
26.4		 3q95B-2gpvA:
36.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 11 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.59A 3uudA-2gpvA:
27.4		 3uudA-2gpvA:
36.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UUD_B_ESTB600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.51A 3uudB-2gpvA:
27.1		 3uudB-2gpvA:
36.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 268
LEU A 271
ALA A 272
MET A 306
ARG A 316
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.51A 4fn9A-2gpvA:
26.4		 4fn9A-2gpvA:
27.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU A 265
LEU A 268
LEU A 271
ALA A 272
TRP A 305
MET A 306
ARG A 316
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
None
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.65A 4fn9B-2gpvA:
26.4		 4fn9B-2gpvA:
27.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU A 268
LEU A 271
GLU A 275
MET A 306
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.58A 4j24A-2gpvA:
27.7		 4j24A-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU A 268
LEU A 271
GLU A 275
MET A 306
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.52A 4j24B-2gpvA:
27.5		 4j24B-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 271
GLU A 275
MET A 306
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.50A 4j24C-2gpvA:
27.6		 4j24C-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 271
ALA A 272
GLU A 275
MET A 306
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.44A 4j24D-2gpvA:
27.5		 4j24D-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 271
GLU A 275
MET A 306
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.51A 4j26A-2gpvA:
27.3		 4j26A-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 271
GLU A 275
MET A 306
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.51A 4j26B-2gpvA:
27.3		 4j26B-2gpvA:
37.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 276
LEU A 294
GLN A 297
MET A 298
GLN A 302
 OHT  A 500 (-4.9A)
None
None
None
None
 0.70A 4ltwA-2gpvA:
26.4		 4ltwA-2gpvA:
27.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 265
LEU A 268
LEU A 271
ALA A 272
MET A 306
ARG A 316
 None
OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
 0.40A 4ltwA-2gpvA:
26.4		 4ltwA-2gpvA:
27.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 271
LEU A 268
LEU A 265
ALA A 264
LEU A 324
 OHT  A 500 ( 4.4A)
OHT  A 500 (-4.1A)
None
None
None
 1.20A 4ltwA-2gpvA:
26.4		 4ltwA-2gpvA:
27.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU A 268
LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.57A 4pxmA-2gpvA:
27.2		 4pxmA-2gpvA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 11 LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.54A 4pxmB-2gpvA:
26.7		 4pxmB-2gpvA:
34.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 268
TRP A 305
MET A 306
ARG A 316
ILE A 438
 OHT  A 500 (-4.1A)
None
OHT  A 500 (-3.9A)
OHT  A 500 (-3.8A)
None
 1.09A 4udcA-2gpvA:
25.4		 4udcA-2gpvA:
31.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA A 272
ASP A 273
GLU A 275
TRP A 305
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-3.1A)
OHT  A 500 (-2.6A)
None
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.72A 4xi3A-2gpvA:
25.7		 4xi3A-2gpvA:
36.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ASP A 273
GLU A 275
LEU A 276
TRP A 305
ARG A 316
HIS A 434
 OHT  A 500 (-3.1A)
OHT  A 500 (-2.6A)
OHT  A 500 (-4.9A)
None
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.94A 4xi3A-2gpvA:
25.7		 4xi3A-2gpvA:
36.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_B_29SB601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 ALA A 272
ASP A 273
TRP A 305
LEU A 309
ARG A 316
 OHT  A 500 (-3.5A)
OHT  A 500 (-3.1A)
None
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.39A 4xi3B-2gpvA:
26.3		 4xi3B-2gpvA:
36.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 271
ALA A 272
TRP A 305
LEU A 309
ARG A 316
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
None
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.39A 4xi3C-2gpvA:
26.3		 4xi3C-2gpvA:
36.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 6 LEU A 268
ASP A 273
GLU A 275
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.1A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.7A)
 0.58A 4xi3C-2gpvA:
26.3		 4xi3C-2gpvA:
36.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 ALA A 272
GLU A 275
TRP A 305
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
None
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.71A 4xi3D-2gpvA:
26.0		 4xi3D-2gpvA:
36.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLU A 275
LEU A 276
TRP A 305
ARG A 316
HIS A 434
 OHT  A 500 (-2.6A)
OHT  A 500 (-4.9A)
None
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 1.04A 4xi3D-2gpvA:
26.0		 4xi3D-2gpvA:
36.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 7 ILE A 349
LEU A 342
ALA A 431
ILE A 310
 None
OHT  A 500 ( 4.7A)
OHT  A 500 (-4.3A)
None
 0.77A 4y03A-2gpvA:
undetectable		 4y03A-2gpvA:
20.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.55A 4zn7A-2gpvA:
27.3		 4zn7A-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 11 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.52A 4zn7B-2gpvA:
27.8		 4zn7B-2gpvA:
36.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.51A 5dx3A-2gpvA:
27.6		 5dx3A-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.61A 5dxbA-2gpvA:
27.7		 5dxbA-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 11 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.63A 5dxbB-2gpvA:
26.8		 5dxbB-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.54A 5dxeA-2gpvA:
27.8		 5dxeA-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 LEU A 268
GLU A 275
LEU A 309
ARG A 316
 OHT  A 500 (-4.1A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.41A 5dxeA-2gpvA:
27.8		 5dxeA-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.66A 5dxeB-2gpvA:
27.2		 5dxeB-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXG_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 9 LEU A 268
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.64A 5dxgA-2gpvA:
27.6		 5dxgA-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 11 LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.51A 5dxgB-2gpvA:
27.0		 5dxgB-2gpvA:
36.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.46A 5gtrA-2gpvA:
25.9		 5gtrA-2gpvA:
37.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 268
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-4.1A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.59A 5hyrA-2gpvA:
27.6		 5hyrA-2gpvA:
36.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 11 LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.63A 5hyrB-2gpvA:
26.8		 5hyrB-2gpvA:
36.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 GLU A 245
VAL A 278
GLY A 312
LEU A 309
 None
None
None
OHT  A 500 ( 4.0A)
 0.85A 5sxqA-2gpvA:
1.1		 5sxqA-2gpvA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 GLU A 245
VAL A 278
GLY A 312
LEU A 309
 None
None
None
OHT  A 500 ( 4.0A)
 0.87A 5syjB-2gpvA:
0.9		 5syjB-2gpvA:
15.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 ALA A 272
MET A 306
LEU A 309
ILE A 438
LEU A 345
 OHT  A 500 (-3.5A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
None
OHT  A 500 (-4.3A)
 0.99A 5toaA-2gpvA:
27.4		 5toaA-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		7 / 12 LEU A 268
LEU A 271
ALA A 272
GLU A 275
MET A 306
LEU A 309
ARG A 316
 OHT  A 500 (-4.1A)
OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.37A 5toaA-2gpvA:
27.4		 5toaA-2gpvA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 12 LEU A 271
GLU A 275
MET A 306
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-2.6A)
OHT  A 500 (-3.9A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.51A 5toaB-2gpvA:
27.5		 5toaB-2gpvA:
37.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGD_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 9 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.56A 5wgdA-2gpvA:
27.5		 5wgdA-2gpvA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 9 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.47A 5wgqA-2gpvA:
27.1		 5wgqA-2gpvA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 10 ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.40A 5wgqB-2gpvA:
27.4		 5wgqB-2gpvA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		5 / 12 GLU A 441
ILE A 438
LEU A 342
GLY A 341
THR A 267
 None
None
OHT  A 500 ( 4.7A)
None
None
 1.23A 5x5qB-2gpvA:
undetectable		 5x5qB-2gpvA:
22.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.61A 6cbzA-2gpvA:
27.5		 6cbzA-2gpvA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		4 / 8 LEU A 268
GLU A 275
LEU A 309
ARG A 316
 OHT  A 500 (-4.1A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
 0.47A 6cbzA-2gpvA:
27.5		 6cbzA-2gpvA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 2gpv ESTROGEN-RELATED
RECEPTOR GAMMA
(Homo
sapiens) 		6 / 10 LEU A 271
ALA A 272
GLU A 275
LEU A 309
ARG A 316
HIS A 434
 OHT  A 500 ( 4.4A)
OHT  A 500 (-3.5A)
OHT  A 500 (-2.6A)
OHT  A 500 ( 4.0A)
OHT  A 500 (-3.8A)
OHT  A 500 ( 4.7A)
 0.54A 6cbzB-2gpvA:
26.8		 6cbzB-2gpvA:
33.63