SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ODV'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		5 / 5 HIS A  58
HIS A  62
HIS A  80
HIS A 104
ASP A 161
 FE  A 201 (-3.2A)
ODV  A 203 (-4.1A)
FE  A 202 ( 3.4A)
FE  A 202 ( 3.3A)
FE  A 201 (-2.4A)
 0.85A 1e9yB-4mlnA:
undetectable		 1e9yB-4mlnA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		4 / 8 ASP A  59
HIS A  58
HIS A 104
HIS A  34
 ODV  A 203 (-2.3A)
FE  A 201 (-3.2A)
FE  A 202 ( 3.3A)
FE  A 201 (-3.4A)
 0.68A 1ei6D-4mlnA:
undetectable		 1ei6D-4mlnA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		5 / 12 HIS A  58
GLY A 164
HIS A  34
GLU A  27
SER A 126
 FE  A 201 (-3.2A)
None
FE  A 201 (-3.4A)
ODV  A 203 (-3.2A)
ODV  A 203 (-2.8A)
 1.25A 2pgfA-4mlnA:
undetectable		 2pgfA-4mlnA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		4 / 8 HIS A 104
ASP A 161
HIS A  80
ASP A  59
 FE  A 202 ( 3.3A)
FE  A 201 (-2.4A)
FE  A 202 ( 3.4A)
ODV  A 203 (-2.3A)
 1.11A 2xadA-4mlnA:
undetectable		 2xadA-4mlnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		4 / 8 HIS A 104
ASP A 161
HIS A  80
ASP A  59
 FE  A 202 ( 3.3A)
FE  A 201 (-2.4A)
FE  A 202 ( 3.4A)
ODV  A 203 (-2.3A)
 1.13A 2xadB-4mlnA:
undetectable		 2xadB-4mlnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		4 / 8 HIS A 104
ASP A 161
HIS A  80
ASP A  59
 FE  A 202 ( 3.3A)
FE  A 201 (-2.4A)
FE  A 202 ( 3.4A)
ODV  A 203 (-2.3A)
 1.12A 2xadC-4mlnA:
undetectable		 2xadC-4mlnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		4 / 8 HIS A 104
ASP A 161
HIS A  80
ASP A  59
 FE  A 202 ( 3.3A)
FE  A 201 (-2.4A)
FE  A 202 ( 3.4A)
ODV  A 203 (-2.3A)
 1.12A 2xadD-4mlnA:
undetectable		 2xadD-4mlnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_B_CP6B563_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		5 / 12 ARG A 158
HIS A 104
ASP A 161
ASP A  59
GLU A  27
 ODV  A 203 (-2.8A)
FE  A 202 ( 3.3A)
FE  A 201 (-2.4A)
ODV  A 203 (-2.3A)
ODV  A 203 (-3.2A)
 1.50A 3lmyB-4mlnA:
undetectable		 3lmyB-4mlnA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		4 / 5 SER A 123
THR A 129
VAL A 105
ASP A 161
 ODV  A 203 ( 4.9A)
ODV  A 203 (-3.3A)
ODV  A 203 ( 4.6A)
FE  A 201 (-2.4A)
 1.13A 4eohA-4mlnA:
undetectable		 4eohA-4mlnA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H9M_A_HAEA929_1
(UREASE)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		5 / 5 HIS A  58
HIS A  62
HIS A  80
HIS A 104
ASP A 161
 FE  A 201 (-3.2A)
ODV  A 203 (-4.1A)
FE  A 202 ( 3.4A)
FE  A 202 ( 3.3A)
FE  A 201 (-2.4A)
 0.90A 4h9mA-4mlnA:
undetectable		 4h9mA-4mlnA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		5 / 6 HIS A  58
HIS A  62
HIS A  80
HIS A 104
ASP A 161
 FE  A 201 (-3.2A)
ODV  A 203 (-4.1A)
FE  A 202 ( 3.4A)
FE  A 202 ( 3.3A)
FE  A 201 (-2.4A)
 0.87A 4ubpC-4mlnA:
undetectable		 4ubpC-4mlnA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_B_ASCB501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		5 / 12 HIS A 104
HIS A  62
ARG A 158
ASP A  59
MET A  72
 FE  A 202 ( 3.3A)
ODV  A 203 (-4.1A)
ODV  A 203 (-2.8A)
ODV  A 203 (-2.3A)
None
 1.40A 5zovB-4mlnA:
undetectable		 5zovB-4mlnA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 4mln PREDICTED HD
PHOSPHOHYDROLASE
PHNZ
(uncultured
bacterium
HF130_AEPn_1) 		4 / 5 THR A 129
HIS A  80
ASP A  59
HIS A 104
 ODV  A 203 (-3.3A)
FE  A 202 ( 3.4A)
ODV  A 203 (-2.3A)
FE  A 202 ( 3.3A)
 0.86A 6dchA-4mlnA:
undetectable		 6dchA-4mlnA:
20.36