SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ODT'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		3 / 3 TRP A 199
VAL A  64
PRO A  65
 None
ODT  A1001 ( 4.4A)
None
 0.71A 1rg1A-2bacA:
undetectable		 1rg1A-2bacA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		3 / 3 TRP A 199
VAL A  64
PRO A  65
 None
ODT  A1001 ( 4.4A)
None
 0.71A 1rh0A-2bacA:
undetectable		 1rh0A-2bacA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 4 VAL A  64
PHE A 168
VAL A 181
TRP A 161
 ODT  A1001 ( 4.4A)
ODT  A1001 (-3.7A)
None
None
 1.36A 2y00A-2bacA:
0.0		 2y00A-2bacA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 PHE A 168
GLY A 169
GLY A 296
MET A  62
 ODT  A1001 (-3.7A)
None
None
ODT  A1001 ( 3.9A)
 0.87A 3v3nB-2bacA:
16.1		 3v3nB-2bacA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 PHE A 168
GLY A 169
GLY A 296
MET A  62
 ODT  A1001 (-3.7A)
None
None
ODT  A1001 ( 3.9A)
 0.87A 3v3nC-2bacA:
16.0		 3v3nC-2bacA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 6 ALA A 285
THR A 326
VAL A 283
TYR A 328
 None
None
None
ODT  A1001 ( 4.0A)
 1.03A 5eclA-2bacA:
undetectable		 5eclA-2bacA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2bac PUTATIVE
AMINOOXIDASE
(Cutibacterium
acnes) 		4 / 8 ALA A 285
THR A 326
VAL A 283
TYR A 328
 None
None
None
ODT  A1001 ( 4.0A)
 0.87A 5ecnD-2bacA:
undetectable		 5ecnD-2bacA:
21.80