SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'ODP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LQT_A_ACTA1866_0
(FPRA)		 1lqt FPRA
(Mycobacterium
tuberculosis) 		4 / 4 ARG A 110
LEU A 112
ASN A 113
VAL A 322
 ACT  A1866 ( 2.5A)
ACT  A1866 (-4.1A)
ACT  A1866 (-4.4A)
ODP  A2458 ( 3.8A)
 0.00A 1lqtA-1lqtA:
66.0		 1lqtA-1lqtA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LQT_B_ACTB1875_0
(FPRA)		 1lqt FPRA
(Mycobacterium
tuberculosis) 		4 / 4 ARG A 110
LEU A 112
ASN A 113
VAL A 322
 ACT  A1866 ( 2.5A)
ACT  A1866 (-4.1A)
ACT  A1866 (-4.4A)
ODP  A2458 ( 3.8A)
 0.05A 1lqtB-1lqtA:
62.8		 1lqtB-1lqtA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LQU_A_ACTA1423_0
(FPRA)		 1lqt FPRA
(Mycobacterium
tuberculosis) 		4 / 4 ARG A 110
LEU A 112
ASN A 113
VAL A 322
 ACT  A1866 ( 2.5A)
ACT  A1866 (-4.1A)
ACT  A1866 (-4.4A)
ODP  A2458 ( 3.8A)
 0.03A 1lquA-1lqtA:
64.3		 1lquA-1lqtA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LQU_B_ACTB1432_0
(FPRA)		 1lqt FPRA
(Mycobacterium
tuberculosis) 		4 / 4 ARG A 110
LEU A 112
ASN A 113
VAL A 322
 ACT  A1866 ( 2.5A)
ACT  A1866 (-4.1A)
ACT  A1866 (-4.4A)
ODP  A2458 ( 3.8A)
 0.07A 1lquB-1lqtA:
62.7		 1lquB-1lqtA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1lqt FPRA
(Mycobacterium
tuberculosis) 		3 / 3 ASP A 118
ILE A 287
VAL A 322
 None
None
ODP  A2458 ( 3.8A)
 0.66A 2avvD-1lqtA:
undetectable		 2avvD-1lqtA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1lqt FPRA
(Mycobacterium
tuberculosis) 		5 / 12 ARG A 320
PRO A 275
LEU A 112
GLY A 198
GLY A 154
 None
None
ACT  A1866 (-4.1A)
None
ODP  A2458 ( 3.4A)
 1.17A 5l6eA-1lqtA:
undetectable		 5l6eA-1lqtA:
18.93