SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OCP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 ILE A 142
MET A  16
GLY A 139
LEU A  50
 None
OCP  A 382 (-4.1A)
None
None
 0.63A 1dzmA-1ex9A:
undetectable		 1dzmA-1ex9A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 12 ASN A 136
LEU A 138
GLY A 139
MET A  16
LEU A 156
 None
None
None
OCP  A 382 (-4.1A)
None
 0.94A 1gs4A-1ex9A:
undetectable		 1gs4A-1ex9A:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 162
ASN A 163
LEU A 131
ILE A 121
 OCP  A 382 ( 4.4A)
None
None
None
 1.02A 1z95A-1ex9A:
0.0		 1z95A-1ex9A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		5 / 8 GLY A  15
GLY A  84
SER A  82
GLY A 106
VAL A 232
 OCP  A 382 (-3.5A)
None
OCP  A 382 (-1.5A)
None
None
 1.38A 3v1nA-1ex9A:
13.9		 3v1nA-1ex9A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 156
GLY A 157
GLU A 160
MET A  16
 None
None
None
OCP  A 382 (-4.1A)
 0.86A 4rjdA-1ex9A:
undetectable
4rjdB-1ex9A:
undetectable		 4rjdA-1ex9A:
14.66
4rjdB-1ex9A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 5 SER A  82
ALA A 107
HIS A 251
LEU A 162
 OCP  A 382 (-1.5A)
None
OCP  A 382 (-3.9A)
OCP  A 382 ( 4.4A)
 1.25A 5dzkf-1ex9A:
0.5
5dzkt-1ex9A:
undetectable		 5dzkf-1ex9A:
23.79
5dzkt-1ex9A:
0.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 211
HIS A 251
LEU A 252
SER A  82
 CA  A 286 ( 4.5A)
OCP  A 382 (-3.9A)
None
OCP  A 382 (-1.5A)
 0.95A 5m8rB-1ex9A:
undetectable		 5m8rB-1ex9A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1ex9 LACTONIZING LIPASE
(Pseudomonas
aeruginosa) 		4 / 8 SER A 211
HIS A 251
LEU A 252
SER A  82
 CA  A 286 ( 4.5A)
OCP  A 382 (-3.9A)
None
OCP  A 382 (-1.5A)
 0.99A 5m8rD-1ex9A:
0.0		 5m8rD-1ex9A:
22.96