SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OAS'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 12 PHE A 259
ALA A 194
GLY A 172
PHE A 201
LEU A  93
 None
None
OAS  A 169 ( 3.1A)
None
None
 1.39A 1brpA-5jd5A:
undetectable		 1brpA-5jd5A:
20.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
ILE A 523
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.31A 1cqeA-1ebvA:
63.1		 1cqeA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
ILE A 523
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.31A 1cqeB-1ebvA:
63.0		 1cqeB-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		8 / 9 VAL A 116
ARG A 120
VAL A 349
TYR A 355
LEU A 359
ILE A 523
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
SCL  A 700 (-3.4A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.40A 1eqgA-1ebvA:
63.6		 1eqgA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 11 VAL A 116
ARG A 120
VAL A 349
SER A 353
TYR A 355
LEU A 359
TYR A 385
ILE A 523
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 (-3.4A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.36A 1eqgB-1ebvA:
63.6		 1eqgB-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 VAL A 116
ARG A 120
VAL A 349
TYR A 355
LEU A 359
TYR A 385
TRP A 387
ILE A 523
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.34A 1eqhA-1ebvA:
63.7		 1eqhA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 VAL A 116
ARG A 120
VAL A 349
TYR A 355
LEU A 359
TYR A 385
TRP A 387
ILE A 523
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.35A 1eqhB-1ebvA:
63.7		 1eqhB-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 10 VAL A 116
ARG A 120
PHE A 205
VAL A 228
VAL A 344
TYR A 348
VAL A 349
ASN A 375
ILE A 523
LEU A 531
 None
SCL  A 700 (-3.9A)
OAS  A 530 ( 4.7A)
None
None
None
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-3.4A)
OAS  A 530 (-4.1A)
 0.30A 1fe2A-1ebvA:
61.4		 1fe2A-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		5 / 10 VAL A 116
ARG A 120
PHE A 209
ILE A 523
LEU A 531
 None
SCL  A 700 (-3.9A)
None
SCL  A 700 (-3.4A)
OAS  A 530 (-4.1A)
 1.19A 1fe2A-1ebvA:
61.4		 1fe2A-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 PHE A 209
LEU A 352
TYR A 355
PHE A 381
TYR A 385
TRP A 387
PHE A 518
GLY A 526
ALA A 527
GLY A 533
LEU A 534
 None
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
OAS  A 530 ( 4.7A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 ( 4.0A)
OAS  A 530 ( 3.3A)
 0.34A 1fe2A-1ebvA:
61.4		 1fe2A-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 12 PHE A 210
LEU A 352
TYR A 355
PHE A 381
PHE A 518
GLY A 526
ALA A 527
 HEM  A 601 (-4.7A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
OAS  A 530 ( 4.7A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
 1.46A 1fe2A-1ebvA:
61.4		 1fe2A-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 PHE A 205
PHE A 209
LEU A 352
TYR A 355
PHE A 381
TYR A 385
TRP A 387
GLY A 526
ALA A 527
GLY A 533
LEU A 534
 OAS  A 530 ( 4.7A)
None
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
OAS  A 530 ( 4.7A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 ( 4.0A)
OAS  A 530 ( 3.3A)
 0.39A 1igxA-1ebvA:
61.2		 1igxA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IGX_A_EPAA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		6 / 12 PHE A 210
LEU A 352
TYR A 355
PHE A 381
GLY A 526
ALA A 527
 HEM  A 601 (-4.7A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
OAS  A 530 ( 4.7A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
 1.48A 1igxA-1ebvA:
61.2		 1igxA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		8 / 8 VAL A 116
ARG A 120
VAL A 344
TYR A 348
VAL A 349
SER A 353
ILE A 523
LEU A 531
 None
SCL  A 700 (-3.9A)
None
None
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-3.4A)
OAS  A 530 (-4.1A)
 0.45A 1igxA-1ebvA:
61.2		 1igxA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 7 VAL A 116
ARG A 120
VAL A 349
LEU A 352
TYR A 355
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.36A 1pthA-1ebvA:
63.0		 1pthA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 7 VAL A 116
ARG A 120
VAL A 349
LEU A 352
TYR A 355
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.35A 1pthB-1ebvA:
63.0		 1pthB-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		8 / 10 VAL A 349
LEU A 352
LEU A 384
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.47A 1pxxA-1ebvA:
31.2		 1pxxA-1ebvA:
63.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
LEU A 384
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.43A 1pxxC-1ebvA:
30.8		 1pxxC-1ebvA:
63.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 12 GLY A  97
GLY A  98
GLY A  99
PHE A 228
HIS A 295
 OAS  A 169 ( 4.3A)
OAS  A 169 ( 4.0A)
OAS  A 169 ( 3.0A)
None
OAS  A 169 ( 4.1A)
 0.93A 1qtiA-5jd5A:
3.6		 1qtiA-5jd5A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 9 GLY A  98
GLY A  99
ALA A 170
PHE A 228
HIS A 295
 OAS  A 169 ( 4.0A)
OAS  A 169 ( 3.0A)
OAS  A 169 ( 3.6A)
None
OAS  A 169 ( 4.1A)
 0.82A 2aceA-5jd5A:
3.5		 2aceA-5jd5A:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
PHE A 518
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.40A 2aylA-1ebvA:
63.4		 2aylA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
ILE A 523
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.35A 2aylB-1ebvA:
63.1		 2aylB-1ebvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 7 GLY A  98
GLY A  99
ALA A 170
PHE A 228
HIS A 295
 OAS  A 169 ( 4.0A)
OAS  A 169 ( 3.0A)
OAS  A 169 ( 3.6A)
None
OAS  A 169 ( 4.1A)
 0.87A 2ha4B-5jd5A:
16.1		 2ha4B-5jd5A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		4 / 5 LEU A 534
GLY A 227
ILE A 337
ILE A 341
 OAS  A 530 ( 3.3A)
None
None
None
 0.81A 2q9rA-1ebvA:
0.0		 2q9rA-1ebvA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		4 / 7 TYR A 348
LEU A 534
LYS A 531
TYR A 385
 None
OAS  A 530 ( 3.3A)
OAS  A 530 (-3.0A)
None
 1.30A 2w98A-1ebvA:
undetectable
2w98B-1ebvA:
undetectable		 2w98A-1ebvA:
21.90
2w98B-1ebvA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		4 / 7 LEU A 203
TRP A 100
ALA A 170
GLY A 199
 None
None
OAS  A 169 ( 3.6A)
OAS  A 169 ( 3.4A)
 0.92A 2wq5A-5jd5A:
undetectable		 2wq5A-5jd5A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 12 LEU A 196
GLY A 199
ILE A 165
GLY A 171
GLY A 172
 None
OAS  A 169 ( 3.4A)
None
OAS  A 169 ( 3.8A)
OAS  A 169 ( 3.1A)
 1.09A 3axzA-5jd5A:
undetectable		 3axzA-5jd5A:
22.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 VAL A 116
VAL A 349
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 534
 None
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 ( 3.3A)
 0.50A 3hs6A-1ebvA:
57.8		 3hs6A-1ebvA:
63.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 PHE A 209
GLY A 227
TYR A 355
ASN A 375
ILE A 377
PHE A 381
TYR A 385
GLY A 526
ALA A 527
GLY A 533
LEU A 534
 None
None
SCL  A 700 (-4.3A)
None
None
OAS  A 530 ( 4.7A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 ( 4.0A)
OAS  A 530 ( 3.3A)
 0.38A 3hs6B-1ebvA:
30.3		 3hs6B-1ebvA:
63.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_B_EPAB1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		6 / 12 PHE A 210
TYR A 355
ILE A 377
PHE A 381
GLY A 526
ALA A 527
 HEM  A 601 (-4.7A)
SCL  A 700 (-4.3A)
None
OAS  A 530 ( 4.7A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
 1.34A 3hs6B-1ebvA:
30.3		 3hs6B-1ebvA:
63.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		6 / 7 PHE A 205
VAL A 344
VAL A 349
LEU A 352
SER A 353
TRP A 387
 OAS  A 530 ( 4.7A)
None
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
None
 0.31A 3hs6B-1ebvA:
30.3		 3hs6B-1ebvA:
63.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		6 / 6 HIS A  90
VAL A 116
SER A 353
LEU A 384
ILE A 517
LEU A 531
 None
None
None
None
None
OAS  A 530 (-4.1A)
 0.45A 3kk6A-1ebvA:
59.7		 3kk6A-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KK6_B_CELB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		6 / 6 VAL A 116
SER A 353
LEU A 384
ILE A 517
ALA A 527
LEU A 531
 None
None
None
None
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.48A 3kk6B-1ebvA:
59.6		 3kk6B-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 HIS A  90
GLN A 192
VAL A 349
TYR A 355
LEU A 359
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
None
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.31A 3ln1A-1ebvA:
58.3		 3ln1A-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 HIS A  90
GLN A 192
VAL A 349
TYR A 355
LEU A 359
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
None
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.29A 3ln1B-1ebvA:
58.3		 3ln1B-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 HIS A  90
VAL A 349
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.32A 3ln1C-1ebvA:
58.3		 3ln1C-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 HIS A  90
GLN A 192
VAL A 349
SER A 353
TYR A 355
LEU A 359
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
None
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.30A 3ln1D-1ebvA:
30.7		 3ln1D-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 VAL A 116
ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.37A 3n8wA-1ebvA:
62.2		 3n8wA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 HIS A  90
ARG A 120
LEU A 352
TYR A 355
TYR A 385
TRP A 387
PHE A 518
ILE A 523
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.45A 3n8xA-1ebvA:
61.6		 3n8xA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 HIS A  90
ARG A 120
LEU A 352
TYR A 355
LEU A 359
TRP A 387
PHE A 518
ILE A 523
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.40A 3n8xB-1ebvA:
61.5		 3n8xB-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 11 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
ILE A 523
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.57A 3n8yA-1ebvA:
61.9		 3n8yA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Y_B_DIFB585_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		12 / 12 VAL A 344
VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
ILE A 523
GLY A 526
ALA A 527
LEU A 531
LEU A 534
 None
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
OAS  A 530 ( 3.3A)
 0.46A 3n8yB-1ebvA:
61.4		 3n8yB-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 VAL A 116
ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.35A 3n8zA-1ebvA:
61.5		 3n8zA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 384
TYR A 385
TRP A 387
ILE A 523
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.37A 3n8zB-1ebvA:
62.0		 3n8zB-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.58A 3nt1A-1ebvA:
30.6		 3nt1A-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.58A 3nt1B-1ebvA:
58.6		 3nt1B-1ebvA:
64.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_A_BEZA999_0
(CHOLINESTERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		4 / 7 GLY A  98
GLY A  99
LEU A 225
HIS A 295
 OAS  A 169 ( 4.0A)
OAS  A 169 ( 3.0A)
None
OAS  A 169 ( 4.1A)
 0.54A 3o9mA-5jd5A:
3.1		 3o9mA-5jd5A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O9M_B_BEZB999_0
(CHOLINESTERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		4 / 6 GLY A  98
GLY A  99
LEU A 225
HIS A 295
 OAS  A 169 ( 4.0A)
OAS  A 169 ( 3.0A)
None
OAS  A 169 ( 4.1A)
 0.55A 3o9mB-5jd5A:
7.8		 3o9mB-5jd5A:
19.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 VAL A 116
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.42A 3pghA-1ebvA:
23.5		 3pghA-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 VAL A 116
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.42A 3pghC-1ebvA:
25.5		 3pghC-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.45A 3pghD-1ebvA:
23.3		 3pghD-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 VAL A 116
ARG A 120
VAL A 349
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.40A 3rr3A-1ebvA:
31.6		 3rr3A-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 VAL A 116
ARG A 120
VAL A 349
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.40A 3rr3B-1ebvA:
31.2		 3rr3B-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 ARG A 120
VAL A 349
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.44A 4coxA-1ebvA:
22.3		 4coxA-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 12 ARG A 120
VAL A 349
TYR A 355
LEU A 384
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.69A 4coxA-1ebvA:
22.3		 4coxA-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		8 / 12 ARG A 120
VAL A 349
SER A 353
TYR A 355
LEU A 384
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.70A 4coxB-1ebvA:
57.9		 4coxB-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 ARG A 120
VAL A 349
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.43A 4coxB-1ebvA:
57.9		 4coxB-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 ARG A 120
VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.44A 4coxC-1ebvA:
14.9		 4coxC-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		8 / 12 ARG A 120
VAL A 349
SER A 353
TYR A 355
LEU A 384
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.70A 4coxD-1ebvA:
30.8		 4coxD-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 ARG A 120
VAL A 349
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.43A 4coxD-1ebvA:
30.8		 4coxD-1ebvA:
64.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 PHE A 205
PHE A 209
TYR A 355
ASN A 375
ILE A 377
PHE A 381
TYR A 385
GLY A 526
ALA A 527
GLY A 533
LEU A 534
 OAS  A 530 ( 4.7A)
None
SCL  A 700 (-4.3A)
None
None
OAS  A 530 ( 4.7A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 ( 4.0A)
OAS  A 530 ( 3.3A)
 0.33A 4e1gA-1ebvA:
58.5		 4e1gA-1ebvA:
62.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		6 / 12 PHE A 210
TYR A 355
ILE A 377
PHE A 381
GLY A 526
ALA A 527
 HEM  A 601 (-4.7A)
SCL  A 700 (-4.3A)
None
OAS  A 530 ( 4.7A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
 1.29A 4e1gA-1ebvA:
58.5		 4e1gA-1ebvA:
62.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 ARG A 120
PHE A 205
PHE A 209
TYR A 355
ILE A 377
PHE A 381
TYR A 385
GLY A 526
ALA A 527
GLY A 533
LEU A 534
 SCL  A 700 (-3.9A)
OAS  A 530 ( 4.7A)
None
SCL  A 700 (-4.3A)
None
OAS  A 530 ( 4.7A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 ( 4.0A)
OAS  A 530 ( 3.3A)
 0.41A 4e1gB-1ebvA:
58.5		 4e1gB-1ebvA:
62.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		6 / 12 PHE A 210
TYR A 355
ILE A 377
PHE A 381
GLY A 526
ALA A 527
 HEM  A 601 (-4.7A)
SCL  A 700 (-4.3A)
None
OAS  A 530 ( 4.7A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
 1.32A 4e1gB-1ebvA:
58.5		 4e1gB-1ebvA:
62.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 12 GLY A  97
GLY A  98
GLY A  99
PHE A 228
HIS A 295
 OAS  A 169 ( 4.3A)
OAS  A 169 ( 4.0A)
OAS  A 169 ( 3.0A)
None
OAS  A 169 ( 4.1A)
 0.92A 4ey6A-5jd5A:
7.7		 4ey6A-5jd5A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 12 GLY A  97
GLY A  98
GLY A  99
PHE A 228
HIS A 295
 OAS  A 169 ( 4.3A)
OAS  A 169 ( 4.0A)
OAS  A 169 ( 3.0A)
None
OAS  A 169 ( 4.1A)
 0.91A 4ey6B-5jd5A:
15.7		 4ey6B-5jd5A:
23.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 MET A 113
VAL A 116
ARG A 120
ILE A 345
VAL A 349
LEU A 352
LEU A 359
TRP A 387
ALA A 527
LEU A 534
 None
None
SCL  A 700 (-3.9A)
None
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
None
SCL  A 700 (-2.9A)
OAS  A 530 ( 3.3A)
 0.74A 4m11B-1ebvA:
57.9		 4m11B-1ebvA:
64.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 12 MET A 113
VAL A 116
ARG A 120
LEU A 352
ALA A 527
LEU A 531
LEU A 534
 None
None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
OAS  A 530 ( 3.3A)
 1.24A 4m11B-1ebvA:
57.9		 4m11B-1ebvA:
64.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		6 / 12 ILE A 345
LEU A 352
LEU A 359
TRP A 387
ALA A 527
LEU A 534
 None
SCL  A 700 ( 4.8A)
None
None
SCL  A 700 (-2.9A)
OAS  A 530 ( 3.3A)
 0.64A 4m11C-1ebvA:
33.5		 4m11C-1ebvA:
64.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 12 MET A 113
ILE A 345
VAL A 349
LEU A 359
TRP A 387
ALA A 527
LEU A 534
 None
None
SCL  A 700 ( 4.6A)
None
None
SCL  A 700 (-2.9A)
OAS  A 530 ( 3.3A)
 0.48A 4m11C-1ebvA:
33.5		 4m11C-1ebvA:
64.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 12 MET A 113
VAL A 116
ILE A 345
VAL A 349
LEU A 359
TRP A 387
LEU A 534
 None
None
None
SCL  A 700 ( 4.6A)
None
None
OAS  A 530 ( 3.3A)
 0.62A 4m11C-1ebvA:
33.5		 4m11C-1ebvA:
64.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 MET A 113
ILE A 345
VAL A 349
LEU A 352
TRP A 387
ILE A 523
GLY A 526
ALA A 527
LEU A 534
LEU A 535
 None
None
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 ( 3.3A)
None
 0.56A 4o1zA-1ebvA:
62.2		 4o1zA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 12 MET A 113
ILE A 523
GLY A 526
ALA A 527
LEU A 531
LEU A 534
LEU A 535
 None
SCL  A 700 (-3.4A)
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
OAS  A 530 ( 3.3A)
None
 1.07A 4o1zA-1ebvA:
62.2		 4o1zA-1ebvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		6 / 12 MET A 113
VAL A 116
LEU A 117
ARG A 120
ALA A 527
LEU A 531
 None
None
None
SCL  A 700 (-3.9A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.92A 4o1zB-1ebvA:
62.4		 4o1zB-1ebvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O33_A_TZNA501_1
(PHOSPHOGLYCERATE
KINASE 1)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 12 ALA A 200
GLY A 199
PHE A 198
LEU A 267
GLY A 171
 None
OAS  A 169 ( 3.4A)
OAS  A 169 ( 4.8A)
None
OAS  A 169 ( 3.8A)
 0.91A 4o33A-5jd5A:
undetectable		 4o33A-5jd5A:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		8 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
LEU A 384
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.65A 4otyA-1ebvA:
30.7		 4otyA-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.39A 4otyA-1ebvA:
30.7		 4otyA-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		8 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
LEU A 384
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.62A 4otyB-1ebvA:
30.6		 4otyB-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.35A 4otyB-1ebvA:
30.6		 4otyB-1ebvA:
64.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		5 / 12 LEU A 534
ASN A 537
GLY A 536
GLN A 208
ILE A 337
 OAS  A 530 ( 3.3A)
None
None
None
None
 1.15A 4p6xI-1ebvA:
undetectable		 4p6xI-1ebvA:
21.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 10 VAL A 116
ARG A 120
VAL A 349
TYR A 355
LEU A 359
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.39A 4ph9A-1ebvA:
58.8		 4ph9A-1ebvA:
64.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 10 VAL A 116
ARG A 120
VAL A 349
TYR A 355
LEU A 359
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.34A 4ph9B-1ebvA:
58.8		 4ph9B-1ebvA:
64.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
MET A 522
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.56A 4rrwA-1ebvA:
58.1		 4rrwA-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
MET A 522
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.55A 4rrwB-1ebvA:
32.7		 4rrwB-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.55A 4rrwC-1ebvA:
58.1		 4rrwC-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 12 VAL A 349
SER A 353
TYR A 355
LEU A 384
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.64A 4rrwC-1ebvA:
58.1		 4rrwC-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		5 / 12 TYR A 355
LEU A 384
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.79A 4rrwD-1ebvA:
58.1		 4rrwD-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.36A 4rrwD-1ebvA:
58.1		 4rrwD-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 TYR A 348
VAL A 349
LEU A 352
TYR A 355
LEU A 384
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.67A 4rrxA-1ebvA:
57.7		 4rrxA-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 TYR A 348
VAL A 349
LEU A 352
TYR A 355
LEU A 384
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.67A 4rrxB-1ebvA:
32.4		 4rrxB-1ebvA:
64.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
MET A 522
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.56A 4rrzA-1ebvA:
58.1		 4rrzA-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
MET A 522
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.55A 4rrzB-1ebvA:
32.7		 4rrzB-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.55A 4rrzC-1ebvA:
58.1		 4rrzC-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_C_LURC705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		7 / 12 VAL A 349
SER A 353
TYR A 355
LEU A 384
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.64A 4rrzC-1ebvA:
58.1		 4rrzC-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		5 / 12 TYR A 355
LEU A 384
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.79A 4rrzD-1ebvA:
58.1		 4rrzD-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.36A 4rrzD-1ebvA:
58.1		 4rrzD-1ebvA:
64.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 9 ARG A 120
VAL A 349
LEU A 352
SER A 353
TYR A 355
LEU A 359
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.38A 4rs0A-1ebvA:
33.8		 4rs0A-1ebvA:
64.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		5 / 12 LEU A 230
ILE A 337
GLY A 338
VAL A 344
LEU A 534
 None
None
None
None
OAS  A 530 ( 3.3A)
 1.10A 4y8wA-1ebvA:
0.0		 4y8wA-1ebvA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 12 LEU A 196
GLY A 199
ILE A 165
GLY A 171
GLY A 172
 None
OAS  A 169 ( 3.4A)
None
OAS  A 169 ( 3.8A)
OAS  A 169 ( 3.1A)
 1.08A 4yvgA-5jd5A:
undetectable		 4yvgA-5jd5A:
22.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 384
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.46A 5ikqA-1ebvA:
33.9		 5ikqA-1ebvA:
63.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 384
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.48A 5ikqB-1ebvA:
33.8		 5ikqB-1ebvA:
63.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 ARG A 120
VAL A 349
LEU A 352
SER A 353
TYR A 355
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.49A 5ikrA-1ebvA:
58.6		 5ikrA-1ebvA:
63.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.42A 5ikrB-1ebvA:
58.5		 5ikrB-1ebvA:
63.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 VAL A 116
ARG A 120
VAL A 349
SER A 353
TYR A 355
LEU A 384
TRP A 387
MET A 522
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.45A 5iktA-1ebvA:
35.0		 5iktA-1ebvA:
63.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 VAL A 116
ARG A 120
VAL A 349
LEU A 352
SER A 353
LEU A 384
TRP A 387
MET A 522
GLY A 526
ALA A 527
LEU A 531
 None
SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.44A 5iktB-1ebvA:
58.8		 5iktB-1ebvA:
63.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		10 / 12 ARG A 120
VAL A 349
LEU A 352
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.56A 5jvzA-1ebvA:
58.5		 5jvzA-1ebvA:
64.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		11 / 12 ARG A 120
VAL A 349
LEU A 352
SER A 353
TYR A 355
LEU A 359
TYR A 385
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 SCL  A 700 (-3.9A)
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
None
SCL  A 700 (-4.3A)
None
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.58A 5jvzB-1ebvA:
58.3		 5jvzB-1ebvA:
64.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 HIS A  90
GLN A 192
VAL A 349
TYR A 355
LEU A 359
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
None
SCL  A 700 ( 4.6A)
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.32A 5jw1A-1ebvA:
57.4		 5jw1A-1ebvA:
64.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 HIS A  90
GLN A 192
LEU A 352
TYR A 355
LEU A 359
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
None
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.36A 5jw1B-1ebvA:
57.4		 5jw1B-1ebvA:
64.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 HIS A  90
GLN A 192
VAL A 349
LEU A 352
TYR A 355
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
None
SCL  A 700 ( 4.6A)
SCL  A 700 ( 4.8A)
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.30A 5kirA-1ebvA:
58.4		 5kirA-1ebvA:
63.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ebv PROSTAGLANDIN H2
SYNTHASE
(Ovis
aries) 		9 / 12 HIS A  90
GLN A 192
VAL A 349
SER A 353
TYR A 355
TRP A 387
GLY A 526
ALA A 527
LEU A 531
 None
None
SCL  A 700 ( 4.6A)
None
SCL  A 700 (-4.3A)
None
SCL  A 700 ( 4.0A)
SCL  A 700 (-2.9A)
OAS  A 530 (-4.1A)
 0.34A 5kirB-1ebvA:
58.7		 5kirB-1ebvA:
63.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5jd5 MGS-MILE3
(uncultured
bacterium) 		5 / 12 PHE A  95
SER A 125
GLY A 103
GLY A  97
ALA A 105
 None
None
None
OAS  A 169 ( 4.3A)
None
 1.08A 5kpcB-5jd5A:
2.3		 5kpcB-5jd5A:
20.85