SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'OAQ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 9 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.38A 1c9sF-5bykA:
undetectable
1c9sG-5bykA:
undetectable		 1c9sF-5bykA:
21.92
1c9sG-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 ILE A 158
PHE A 162
LEU A 255
LEU A 249
MET A 242
 None
OAQ  A 302 (-4.6A)
None
None
OAQ  A 302 ( 4.0A)
 1.20A 1dtlA-5tiwA:
undetectable		 1dtlA-5tiwA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 THR A  98
TYR A  51
ILE A  56
ILE A  57
ALA A 173
 None
None
None
OAQ  A 302 ( 4.9A)
None
 1.15A 1jtxA-5tiwA:
undetectable		 1jtxA-5tiwA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 9 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.40A 1utdA-5bykA:
undetectable
1utdK-5bykA:
undetectable		 1utdA-5bykA:
21.92
1utdK-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		3 / 3 SER A 132
ASP A 100
CYH A 104
 A3P  A 301 (-2.5A)
OAQ  A 302 (-2.5A)
None
 1.16A 2br4E-5tiwA:
undetectable		 2br4E-5tiwA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 12 GLY A  96
LEU A 156
MET A  38
LEU A  83
LEU A  79
 None
None
OAQ  A 302 (-4.3A)
None
None
 1.04A 3cs8A-5bykA:
undetectable		 3cs8A-5bykA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 12 MET A 233
LEU A 236
THR A 237
LEU A 149
LEU A 246
 None
None
OAQ  A 302 (-3.8A)
None
None
 1.15A 3hm1A-5bykA:
undetectable		 3hm1A-5bykA:
22.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 12 HIS A  37
PHE A  39
VAL A 127
GLY A 143
ASP A 144
 OAQ  A 302 ( 4.6A)
None
OAQ  A 302 (-4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-3.3A)
 1.12A 4mubA-5bykA:
44.7		 4mubA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 PRO A  16
HIS A  37
MET A  38
PHE A  39
LEU A  92
VAL A 128
GLY A 143
ASP A 144
PHE A 153
THR A 157
MET A 233
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
OAQ  A 302 (-3.8A)
 0.19A 4mubA-5bykA:
44.7		 4mubA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		6 / 12 PRO A  16
HIS A  37
PHE A  39
LEU A  92
VAL A 128
THR A 234
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
None
 1.22A 4mubA-5bykA:
44.7		 4mubA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
HIS A  52
LEU A 101
VAL A 137
THR A 243
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
 1.18A 4mubA-5tiwA:
39.6		 4mubA-5tiwA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 12 PRO A  31
HIS A  52
MET A  53
LEU A 101
VAL A 137
GLY A 152
ASP A 153
PHE A 162
MET A 242
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.5A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
 0.38A 4mubA-5tiwA:
39.6		 4mubA-5tiwA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 HIS A  37
MET A  38
PHE A  39
ILE A  42
LEU A  92
VAL A 128
GLY A 143
PHE A 153
THR A 157
MET A 233
LEU A 236
THR A 237
 OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
None
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
None
OAQ  A 302 (-3.8A)
 0.32A 5byjA-5bykA:
44.6		 5byjA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 12 HIS A  52
MET A  53
ILE A  57
LEU A 101
VAL A 137
GLY A 152
PHE A 162
MET A 242
LEU A 245
THR A 246
 OAQ  A 302 ( 4.9A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.5A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.48A 5byjA-5tiwA:
39.7		 5byjA-5tiwA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		6 / 12 PRO A  16
HIS A  37
LEU A  92
VAL A 127
VAL A 128
THR A 234
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
 1.37A 5bykA-5bykA:
46.1		 5bykA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 PRO A  16
HIS A  37
MET A  38
ILE A  42
LEU A  92
VAL A 127
VAL A 128
LEU A 147
PHE A 153
THR A 157
MET A 233
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
OAQ  A 302 (-3.8A)
 0.22A 5bykA-5bykA:
46.1		 5bykA-5bykA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
HIS A  52
LEU A 101
VAL A 137
THR A 243
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
 1.16A 5bykA-5tiwA:
39.8		 5bykA-5tiwA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		11 / 12 PRO A  31
HIS A  52
MET A  53
ILE A  57
LEU A 101
VAL A 136
VAL A 137
LEU A 156
PHE A 162
MET A 242
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
None
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
 0.37A 5bykA-5tiwA:
39.8		 5bykA-5tiwA:
75.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.42A 5eeuD-5bykA:
undetectable
5eeuE-5bykA:
undetectable		 5eeuD-5bykA:
21.92
5eeuE-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.42A 5eevD-5bykA:
undetectable
5eevE-5bykA:
undetectable		 5eevD-5bykA:
21.92
5eevE-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.42A 5eewD-5bykA:
undetectable
5eewE-5bykA:
undetectable		 5eewD-5bykA:
21.92
5eewE-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.41A 5eeyD-5bykA:
undetectable
5eeyE-5bykA:
undetectable		 5eeyD-5bykA:
21.92
5eeyE-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.41A 5ef0D-5bykA:
undetectable
5ef0E-5bykA:
undetectable		 5ef0D-5bykA:
21.92
5ef0E-5bykA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		5 / 10 THR A  20
SER A  12
HIS A  37
ALA A  88
THR A  94
 A3P  A 301 (-2.8A)
None
OAQ  A 302 ( 4.6A)
None
None
 1.41A 5ef1D-5bykA:
undetectable
5ef1E-5bykA:
undetectable		 5ef1D-5bykA:
21.92
5ef1E-5bykA:
21.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 PRO A  16
MET A  38
ILE A  42
LEU A  92
VAL A 127
VAL A 128
ILE A 140
LEU A 147
PHE A 153
LEU A 236
THR A 237
LEU A 240
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
None
OAQ  A 302 ( 4.8A)
None
OAQ  A 302 (-3.8A)
None
 0.27A 5tiwA-5bykA:
39.8		 5tiwA-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		12 / 12 PRO A  31
MET A  53
ILE A  57
LEU A 101
VAL A 136
VAL A 137
ILE A 149
LEU A 156
PHE A 162
LEU A 245
THR A 246
LEU A 249
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.4A)
None
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
None
 0.01A 5tiwA-5tiwA:
45.7		 5tiwA-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		11 / 12 PRO A  16
MET A  38
ILE A  42
ASP A  91
LEU A  92
VAL A 128
ILE A 140
ASP A 144
PHE A 153
LEU A 236
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
None
OAQ  A 302 (-3.8A)
 0.41A 5tiwB-5bykA:
39.2		 5tiwB-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 12 MET A  53
ILE A  57
ASP A 100
VAL A 137
ILE A 149
ASP A 153
PHE A 162
SER A 166
LEU A 245
THR A 246
 OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.56A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
ASP A 100
LEU A 101
SER A 169
LEU A 156
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
None
None
 1.30A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
ILE A  56
ASP A 100
LEU A 101
SER A 169
 OAQ  A 302 (-4.7A)
None
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
None
 1.19A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
LEU A 170
VAL A 137
ILE A 149
LEU A 156
 OAQ  A 302 (-4.7A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.4A)
None
 1.33A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		11 / 12 PRO A  31
MET A  53
ILE A  57
ASP A 100
LEU A 101
VAL A 137
ILE A 149
ASP A 153
PHE A 162
LEU A 245
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.32A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		5 / 12 PRO A  31
MET A  53
ILE A  57
LEU A 101
LEU A 265
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
None
 1.31A 5tiwB-5tiwA:
43.0		 5tiwB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		8 / 9 PRO A  16
MET A  38
LEU A  92
VAL A 128
LEU A 129
ILE A 140
ASP A 144
PHE A 153
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
None
None
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
 0.39A 5tixA-5bykA:
39.8		 5tixA-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIX_A_OQRA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		9 / 9 PRO A  31
MET A  53
LEU A 101
VAL A 137
LEU A 138
ILE A 149
ASP A 153
PHE A 162
SER A 166
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
 0.31A 5tixA-5tiwA:
42.9		 5tixA-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		9 / 10 PRO A  16
MET A  38
ILE A  42
LEU A  92
VAL A 128
LEU A 129
ASP A 144
PHE A 153
GLU A 158
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
None
 0.55A 5tixB-5bykA:
39.6		 5tixB-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 10 PRO A  31
MET A  53
ILE A  57
LEU A 101
VAL A 137
LEU A 138
ASP A 153
PHE A 162
SER A 166
GLU A 167
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
None
 0.31A 5tixB-5tiwA:
43.0		 5tixB-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		10 / 11 PRO A  16
MET A  38
ILE A  42
ASP A  91
VAL A 128
ASP A 144
PHE A 153
MET A 233
LEU A 236
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
None
None
OAQ  A 302 (-3.8A)
 0.38A 5tiyA-5bykA:
39.7		 5tiyA-5bykA:
75.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 11 MET A  53
ILE A  57
ASP A 100
VAL A 137
ASP A 153
PHE A 162
SER A 166
MET A 242
LEU A 245
THR A 246
 OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.50A 5tiyA-5tiwA:
43.0		 5tiyA-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TIY_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		10 / 11 PRO A  31
MET A  53
ILE A  57
ASP A 100
VAL A 137
ASP A 153
PHE A 162
MET A 242
LEU A 245
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.22A 5tiyA-5tiwA:
43.0		 5tiyA-5tiwA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		10 / 10 MET A  38
ILE A  42
ASP A  91
LEU A  92
VAL A 128
ASP A 144
PHE A 153
THR A 157
MET A 233
THR A 237
 OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
OAQ  A 302 (-3.8A)
 0.33A 6b4yA-5bykA:
43.3		 6b4yA-5bykA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B4Y_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		9 / 10 MET A  53
ILE A  57
ASP A 100
LEU A 101
VAL A 137
ASP A 153
PHE A 162
MET A 242
THR A 246
 OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
 0.46A 6b4yA-5tiwA:
39.5		 6b4yA-5tiwA:
75.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		7 / 12 PRO A  16
HIS A  37
ASP A  91
LEU A  92
VAL A 127
VAL A 128
THR A 234
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
 1.32A 6b50A-5bykA:
44.2		 6b50A-5bykA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		6 / 12 PRO A  16
HIS A  37
MET A  38
ASP A  91
LEU A  92
SER A 160
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
None
 1.49A 6b50A-5bykA:
44.2		 6b50A-5bykA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		11 / 12 PRO A  16
HIS A  37
MET A  38
ASP A  91
LEU A  92
VAL A 127
VAL A 128
ASP A 144
PHE A 153
MET A 233
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 ( 4.6A)
OAQ  A 302 (-4.3A)
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.3A)
OAQ  A 302 ( 4.8A)
None
OAQ  A 302 (-3.8A)
 0.26A 6b50A-5bykA:
44.2		 6b50A-5bykA:
99.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		6 / 12 PRO A  31
HIS A  52
ASP A 100
LEU A 101
VAL A 137
THR A 243
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
None
 1.10A 6b50A-5tiwA:
39.7		 6b50A-5tiwA:
75.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B50_A_OAQA302_0
(SULFOTRANSFERASE
OXAMNIQUINE
RESISTANCE PROTEIN)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		12 / 12 PRO A  31
HIS A  52
MET A  53
ASP A 100
LEU A 101
VAL A 136
VAL A 137
ASP A 153
PHE A 162
SER A 166
MET A 242
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-4.5A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
 0.51A 6b50A-5tiwA:
39.7		 6b50A-5tiwA:
75.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		11 / 12 PRO A  16
MET A  38
ILE A  42
LEU A  92
VAL A 127
VAL A 128
LEU A 147
PHE A 153
MET A 233
LEU A 236
THR A 237
 OAQ  A 302 (-4.4A)
OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.9A)
OAQ  A 302 (-4.0A)
None
OAQ  A 302 ( 4.8A)
None
None
OAQ  A 302 (-3.8A)
 0.37A 6b52A-5bykA:
39.8		 6b52A-5bykA:
75.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		6 / 12 PRO A  31
MET A  53
ILE A  57
LEU A 101
SER A 166
LEU A 265
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-3.5A)
None
 1.44A 6b52A-5tiwA:
42.9		 6b52A-5tiwA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		12 / 12 PRO A  31
MET A  53
ILE A  57
LEU A 101
VAL A 136
VAL A 137
LEU A 156
PHE A 162
SER A 166
MET A 242
LEU A 245
THR A 246
 OAQ  A 302 (-4.7A)
OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 ( 4.1A)
None
OAQ  A 302 (-4.0A)
None
OAQ  A 302 (-4.6A)
OAQ  A 302 (-3.5A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 ( 4.4A)
OAQ  A 302 (-3.5A)
 0.29A 6b52A-5tiwA:
42.9		 6b52A-5tiwA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 5byk SULFOTRANSFERASE
(Schistosoma
mansoni) 		12 / 12 MET A  38
ILE A  42
ASP A  91
LEU A  92
VAL A 128
ASP A 144
LEU A 147
PHE A 153
THR A 157
MET A 233
THR A 237
LEU A 240
 OAQ  A 302 (-4.3A)
None
OAQ  A 302 (-2.7A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.3A)
None
OAQ  A 302 ( 4.8A)
OAQ  A 302 (-2.6A)
None
OAQ  A 302 (-3.8A)
None
 0.46A 6b54A-5bykA:
39.3		 6b54A-5bykA:
75.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		11 / 12 MET A  53
ILE A  57
ASP A 100
LEU A 101
VAL A 137
ASP A 153
LEU A 156
PHE A 162
MET A 242
THR A 246
LEU A 249
 OAQ  A 302 (-4.5A)
OAQ  A 302 ( 4.9A)
OAQ  A 302 (-2.5A)
OAQ  A 302 ( 4.1A)
OAQ  A 302 (-4.0A)
OAQ  A 302 (-3.1A)
None
OAQ  A 302 (-4.6A)
OAQ  A 302 ( 4.0A)
OAQ  A 302 (-3.5A)
None
 0.36A 6b54A-5tiwA:
42.6		 6b54A-5tiwA:
99.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5tiw SULFOTRANSFERASE
(Schistosoma
haematobium) 		3 / 3 ILE A  57
ASN A  36
CYH A  50
 OAQ  A 302 ( 4.9A)
None
None
 0.82A 6bp4A-5tiwA:
undetectable		 6bp4A-5tiwA:
22.98