SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NX3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1M_A_CAMA1422_0 (CYTOCHROME P450-CAM)	3qci	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA (Homo sapiens)	4 / 7	TYR A 880 VAL A1064 GLY A1065 THR A1105	None None NX3 A2001 ( 4.5A) NX3 A2001 ( 4.6A)	0.93A	2a1mA-3qciA: undetectable	2a1mA-3qciA: 20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V35_A_NTIA317_1 (ALDOSE REDUCTASE)	3qci	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA (Homo sapiens)	4 / 8	TRP A1026 HIS A1022 PHE A1041 PRO A1032	None None NX3 A2001 (-4.1A) NX3 A2001 (-4.0A)	1.40A	3v35A-3qciA: undetectable	3v35A-3qciA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TL8_A_X2NA502_2 (PROTEIN CYP51)	3qci	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE GAMMA (Homo sapiens)	4 / 6	PRO A1032 PRO A1037 LEU A1039 PHE A1041	NX3 A2001 (-4.0A) None None NX3 A2001 (-4.1A)	1.22A	5tl8A-3qciA: undetectable	5tl8A-3qciA: 21.92