SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NVC'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3e3u PEPTIDE DEFORMYLASE
(Mycobacterium
tuberculosis) 		4 / 5 ILE A  57
ARG A   7
TRP A 186
TYR A  41
 NVC  A 202 (-4.8A)
None
None
None
 1.47A 2zlcA-3e3uA:
undetectable		 2zlcA-3e3uA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 3e3u PEPTIDE DEFORMYLASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  58
SER A 108
VAL A   4
ALA A  53
HIS A 148
 None
None
NVC  A 202 (-4.6A)
None
NI  A 200 ( 3.2A)
 1.20A 3d91B-3e3uA:
undetectable		 3d91B-3e3uA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_1
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 3e3u PEPTIDE DEFORMYLASE
(Mycobacterium
tuberculosis) 		4 / 6 CYH A 106
ASN A  55
LEU A 153
GLU A 149
 NI  A 200 ( 2.3A)
None
None
NVC  A 201 (-2.6A)
 1.33A 4wcxC-3e3uA:
undetectable		 4wcxC-3e3uA:
17.39