SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NRQ'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1AFS_B_TESB325_1 (3-ALPHA-HYDROXYSTEROID DEHYDROGENASE) |
1uis | RED FLUORESCENTPROTEIN FP611 (Entacmaeaquadricolor) | 4 / 7 | HIS A 197THR A 108TRP A 90TYR A 178 | NRQ A 63 (-3.6A)NoneNRQ A 63 ( 4.1A)None | 1.33A | 1afsB-1uisA:undetectable | 1afsB-1uisA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1FM4_A_DXCA1002_0 (MAJOR POLLENALLERGEN BET V 1-L) |
4i2y | RGECO1 (Gallusgallus;Rattusnorvegicus;Discosomasp.) | 5 / 12 | ILE A 262TYR A 88VAL A 92ILE A 76LEU A 218 | NoneNoneNoneNRQ A 224 ( 4.7A)None | 1.21A | 1fm4A-4i2yA:undetectable | 1fm4A-4i2yA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1IG3_A_VIBA502_1 (THIAMINPYROPHOSPHOKINASE) |
5ukg | K-GECO (Entacmaeaquadricolor) | 4 / 8 | LEU A 63SER A 265ASN A 32GLN A 273 | NoneNoneNRQ A 186 ( 3.6A)None | 1.14A | 1ig3A-5ukgA:undetectable1ig3B-5ukgA:undetectable | 1ig3A-5ukgA:20.441ig3B-5ukgA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1IG3_B_VIBB501_1 (THIAMINPYROPHOSPHOKINASE) |
5ukg | K-GECO (Entacmaeaquadricolor) | 4 / 7 | GLN A 273LEU A 63SER A 265ASN A 32 | NoneNoneNoneNRQ A 186 ( 3.6A) | 1.25A | 1ig3A-5ukgA:undetectable1ig3B-5ukgA:undetectable | 1ig3A-5ukgA:20.441ig3B-5ukgA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1M2Z_D_DEXD401_1 (GLUCOCORTICOIDRECEPTOR) |
3cfh | GFP-LIKEPHOTOSWITCHABLEFLUORESCENT PROTEIN (Anemoniasulcata) | 5 / 12 | MET L 41CYH L 26ILE A 121PHE L 24LEU L 51 | NRQ A 65 ( 3.5A)NoneNoneNoneNone | 1.42A | 1m2zD-3cfhL:undetectable | 1m2zD-3cfhL:11.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1Q0Y_H_MOIH401_1 (FAB 9B1, HEAVY CHAINFAB 9B1, LIGHT CHAIN) |
3cfh | GFP-LIKEPHOTOSWITCHABLEFLUORESCENT PROTEIN (Anemoniasulcata) | 4 / 7 | GLU A 145GLU A 195ILE A 70LEU A 154 | NRQ A 65 ( 3.3A)NoneNoneNone | 1.25A | 1q0yH-3cfhA:undetectable1q0yL-3cfhA:undetectable | 1q0yH-3cfhA:22.641q0yL-3cfhA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1U72_A_MTXA188_1 (DIHYDROFOLATEREDUCTASE) |
3u0n | MRUBY (Entacmaeaquadricolor) | 5 / 12 | ALA A 54GLU A 208SER A 61LEU A 199TYR A 96 | NoneNoneNoneNRQ A 64 ( 3.0A)None | 1.34A | 1u72A-3u0nA:undetectable | 1u72A-3u0nA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1WRL_B_TFPB201_1 (TROPONIN C, SLOWSKELETAL AND CARDIACMUSCLES) |
3cfh | GFP-LIKEPHOTOSWITCHABLEFLUORESCENT PROTEIN (Anemoniasulcata) | 5 / 9 | GLU A 195GLU A 145MET A 160LEU A 159GLU A 214 | NoneNRQ A 65 ( 3.3A)NRQ A 65 ( 3.6A)NoneNRQ A 65 ( 3.1A) | 1.29A | 1wrlA-3cfhA:undetectable1wrlB-3cfhA:undetectable | 1wrlA-3cfhA:18.631wrlB-3cfhA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1WRL_F_TFPF209_1 (TROPONIN C, SLOWSKELETAL AND CARDIACMUSCLES) |
3cfh | GFP-LIKEPHOTOSWITCHABLEFLUORESCENT PROTEIN (Anemoniasulcata) | 5 / 10 | GLU A 195GLU A 145MET A 160LEU A 159GLU A 214 | NoneNRQ A 65 ( 3.3A)NRQ A 65 ( 3.6A)NoneNRQ A 65 ( 3.1A) | 1.42A | 1wrlE-3cfhA:undetectable1wrlF-3cfhA:undetectable | 1wrlE-3cfhA:18.631wrlF-3cfhA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2F7F_A_NIOA601_1 (NICOTINATEPHOSPHORIBOSYLTRANSFERASE, PUTATIVE) |
3bxa | FAR-RED FLUORESCENTPROTEIN MKATE (Entacmaeaquadricolor) | 4 / 6 | ARG A 197GLY A 156THR A 176ARG A 92 | NRQ A 63 ( 3.9A)NoneNoneNRQ A 63 ( 2.6A) | 1.08A | 2f7fA-3bxaA:undetectable | 2f7fA-3bxaA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2F7F_A_NIOA601_1 (NICOTINATEPHOSPHORIBOSYLTRANSFERASE, PUTATIVE) |
3rwa | FLUORESCENT PROTEINFP480 (Entacmaeaquadricolor) | 4 / 6 | ARG A 30GLY A 226THR A 9ARG A 162 | NRQ A 133 ( 3.8A)NoneNoneNRQ A 133 ( 2.7A) | 1.00A | 2f7fA-3rwaA:undetectable | 2f7fA-3rwaA:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2F7F_A_NIOA601_1 (NICOTINATEPHOSPHORIBOSYLTRANSFERASE, PUTATIVE) |
5bql | FLUORESCENT PROTEINCYOFP (Escherichiacoli) | 4 / 6 | ARG A 201GLY A 160THR A 180ARG A 96 | NRQ A 67 ( 3.8A)NoneNoneNRQ A 67 ( 2.5A) | 1.03A | 2f7fA-5bqlA:undetectable | 2f7fA-5bqlA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2F7F_A_NIOA601_1 (NICOTINATEPHOSPHORIBOSYLTRANSFERASE, PUTATIVE) |
5lk4 | MSCARLET (Discosomasp.) | 4 / 6 | ARG A 198GLY A 160THR A 180ARG A 96 | NRQ A 67 ( 4.3A)NoneNoneNRQ A 67 ( 3.0A) | 1.03A | 2f7fA-5lk4A:undetectable | 2f7fA-5lk4A:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3P73_A_ACTA275_0 (MHC RFP-Y CLASS IALPHA CHAIN) |
3bxa | FAR-RED FLUORESCENTPROTEIN MKATE (Entacmaeaquadricolor) | 3 / 3 | ILE A 70VAL A 195ARG A 197 | NoneNoneNRQ A 63 ( 3.9A) | 0.49A | 3p73A-3bxaA:1.4 | 3p73A-3bxaA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3QJ7_A_SPMA264_1 (THYMIDYLATE SYNTHASE) |
5bql | FLUORESCENT PROTEINCYOFP (Escherichiacoli) | 4 / 8 | ARG A 201ALA A 223LEU A 80ASP A 82 | NRQ A 67 ( 3.8A)NoneNoneNone | 0.78A | 3qj7A-5bqlA:undetectable3qj7D-5bqlA:undetectable | 3qj7A-5bqlA:20.583qj7D-5bqlA:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A84_A_DXCA1160_0 (MAJOR POLLENALLERGEN BET V 1-A) |
4i2y | RGECO1 (Gallusgallus;Rattusnorvegicus;Discosomasp.) | 5 / 12 | ILE A 262TYR A 88VAL A 92ILE A 76LEU A 218 | NoneNoneNoneNRQ A 224 ( 4.7A)None | 1.24A | 4a84A-4i2yA:undetectable | 4a84A-4i2yA:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4F8Y_A_VK3A202_1 (NADPH QUINONEOXIDOREDUCTASE) |
5lk4 | MSCARLET (Discosomasp.) | 4 / 5 | ARG A 198TYR A 84TYR A 182LEU A 158 | NRQ A 67 ( 4.3A)NoneNoneNone | 1.35A | 4f8yA-5lk4A:undetectable4f8yB-5lk4A:undetectable | 4f8yA-5lk4A:21.284f8yB-5lk4A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4FWD_A_BO2A801_1 (TTC1975 PEPTIDASE) |
5lk4 | MSCARLET (Discosomasp.) | 5 / 9 | VAL A 212VAL A 211ILE A 30GLY A 32ALA A 45 | NoneNoneNoneNoneNRQ A 67 ( 3.3A) | 1.12A | 4fwdA-5lk4A:undetectable | 4fwdA-5lk4A:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4K38_B_SAMB504_0 (ANAEROBICSULFATASE-MATURATINGENZYME) |
5lk4 | MSCARLET (Discosomasp.) | 5 / 12 | PHE A 57GLN A 214LEU A 47VAL A 49ILE A 30 | NoneNRQ A 67 ( 4.5A)NoneNoneNone | 1.24A | 4k38B-5lk4A:undetectable | 4k38B-5lk4A:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4KRH_B_SAMB900_1 (PHOSPHOETHANOLAMINEN-METHYLTRANSFERASE2) |
4i2y | RGECO1 (Gallusgallus;Rattusnorvegicus;Discosomasp.) | 4 / 4 | ILE A 112SER A 62ASP A 115ASP A 363 | NRQ A 224 ( 3.9A)NRQ A 224 ( 4.5A)None CA A 501 (-3.0A) | 1.31A | 4krhB-4i2yA:undetectable | 4krhB-4i2yA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4M93_B_ACTB303_0 (S25-26 FAB (IGG1K)HEAVY CHAINS25-26 FAB (IGG1K)LIGHT CHAIN) |
3cfh | GFP-LIKEPHOTOSWITCHABLEFLUORESCENT PROTEINGFP-LIKEPHOTOSWITCHABLEFLUORESCENT PROTEIN (Anemoniasulcata;Anemoniasulcata) | 4 / 5 | GLY L 37ALA A 216PHE A 69GLU A 214 | NoneNoneNoneNRQ A 65 ( 3.1A) | 0.89A | 4m93B-3cfhL:undetectable4m93C-3cfhL:undetectable | 4m93B-3cfhL:15.424m93C-3cfhL:14.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4M93_B_ACTB303_0 (S25-26 FAB (IGG1K)HEAVY CHAINS25-26 FAB (IGG1K)LIGHT CHAIN) |
3rwa | FLUORESCENT PROTEINFP480 (Entacmaeaquadricolor) | 4 / 5 | GLY A 107ALA A 50PHE A 139GLU A 48 | NoneNoneNoneNRQ A 133 ( 3.9A) | 1.06A | 4m93B-3rwaA:undetectable4m93C-3rwaA:undetectable | 4m93B-3rwaA:19.444m93C-3rwaA:19.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4M93_B_ACTB303_0 (S25-26 FAB (IGG1K)HEAVY CHAINS25-26 FAB (IGG1K)LIGHT CHAIN) |
3u0n | MRUBY (Entacmaeaquadricolor) | 4 / 5 | GLY A 37ALA A 217PHE A 69GLU A 215 | NoneNoneNoneNRQ A 64 ( 3.0A) | 1.05A | 4m93B-3u0nA:undetectable4m93C-3u0nA:undetectable | 4m93B-3u0nA:20.594m93C-3u0nA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4M93_B_ACTB303_0 (S25-26 FAB (IGG1K)HEAVY CHAINS25-26 FAB (IGG1K)LIGHT CHAIN) |
5ukg | K-GECO (Entacmaeaquadricolor) | 4 / 5 | GLY A 159ALA A 106PHE A 191GLU A 104 | NoneNoneNoneNRQ A 186 ( 3.6A) | 0.97A | 4m93B-5ukgA:undetectable4m93C-5ukgA:undetectable | 4m93B-5ukgA:undetectable4m93C-5ukgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ODO_A_FK5A205_1 (PEPTIDYL-PROLYLCIS-TRANS ISOMERASESLYD) |
5bql | FLUORESCENT PROTEINCYOFP (Escherichiacoli) | 5 / 10 | LEU A 62LEU A 203ILE A 47LEU A 19PHE A 59 | NoneNRQ A 67 ( 4.2A)NoneNoneNone | 1.07A | 4odoA-5bqlA:undetectable | 4odoA-5bqlA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5B2Q_A_ACTA1728_0 (CRISPR-ASSOCIATEDENDONUCLEASE CAS9) |
1uis | RED FLUORESCENTPROTEIN FP611 (Entacmaeaquadricolor) | 3 / 3 | ASN A 143SER A 158ARG A 92 | NRQ A 63 ( 3.1A)NRQ A 63 ( 2.4A)NRQ A 63 ( 3.1A) | 0.94A | 5b2qA-1uisA:undetectable | 5b2qA-1uisA:8.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5IKT_B_TLFB601_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
5bql | FLUORESCENT PROTEINCYOFP (Escherichiacoli) | 3 / 3 | TYR A 121TYR A 83SER A 87 | NRQ A 67 ( 4.5A)NoneNone | 1.00A | 5iktB-5bqlA:undetectable | 5iktB-5bqlA:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5IKT_B_TLFB601_1 (PROSTAGLANDIN G/HSYNTHASE 2) |
5lk4 | MSCARLET (Discosomasp.) | 3 / 3 | TYR A 121TYR A 83SER A 87 | NRQ A 67 ( 4.5A)NoneNone | 0.99A | 5iktB-5lk4A:undetectable | 5iktB-5lk4A:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5KIR_B_RCXB601_2 (PROSTAGLANDIN G/HSYNTHASE 2) |
1uis | RED FLUORESCENTPROTEIN FP611 (Entacmaeaquadricolor) | 4 / 4 | LEU A 58ARG A 92ILE A 57PHE A 102 | NoneNRQ A 63 ( 3.1A)NoneNone | 1.33A | 5kirB-1uisA:undetectable | 5kirB-1uisA:18.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6EP4_A_DMEA601_1 (CHOLINESTERASE) |
3cfh | GFP-LIKEPHOTOSWITCHABLEFLUORESCENT PROTEIN (Anemoniasulcata) | 4 / 5 | TYR A 72GLU A 195TYR A 213HIS A 197 | NoneNoneNoneNRQ A 65 ( 3.8A) | 1.29A | 6ep4A-3cfhA:undetectable | 6ep4A-3cfhA:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6IEY_A_CLMA401_0 (ESTERASE) |
1uis | RED FLUORESCENTPROTEIN FP611 (Entacmaeaquadricolor) | 5 / 11 | ILE A 70TYR A 178LEU A 154GLY A 156SER A 158 | ACY A1001 (-4.8A)NoneNoneNoneNRQ A 63 ( 2.4A) | 1.05A | 6ieyA-1uisA:undetectable6ieyB-1uisA:undetectable | 6ieyA-1uisA:21.346ieyB-1uisA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6IEY_A_CLMA401_0 (ESTERASE) |
3cfh | GFP-LIKEPHOTOSWITCHABLEFLUORESCENT PROTEIN (Anemoniasulcata) | 5 / 11 | ILE A 70TYR A 178LEU A 154GLY A 156SER A 158 | NoneNoneNoneNoneNRQ A 65 ( 2.0A) | 1.19A | 6ieyA-3cfhA:undetectable6ieyB-3cfhA:undetectable | 6ieyA-3cfhA:19.386ieyB-3cfhA:19.38 |