SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NLG'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 3zzf ACETYLGLUTAMATE
KINASE
(Saccharomyces
cerevisiae) 		5 / 12 ASN A 247
LEU A 210
GLN A 244
LEU A 173
THR A 136
 NLG  A1360 (-2.8A)
None
None
None
NLG  A1360 (-4.9A)
 1.45A 1a28A-3zzfA:
undetectable		 1a28A-3zzfA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1oh9 ACETYLGLUTAMATE
KINASE
(Escherichia
coli) 		4 / 5 LEU A  14
SER A 147
LEU A  80
GLY A  10
 None
NLG  A1260 ( 3.7A)
NLG  A1260 ( 4.7A)
ALF  A1261 ( 3.1A)
 0.81A 1a4lC-1oh9A:
undetectable		 1a4lC-1oh9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 9 VAL A 159
GLY A 157
ILE A 156
THR A  96
SER A  83
 NLG  A1302 ( 4.5A)
None
None
None
None
 1.23A 1gtnL-2bufA:
undetectable
1gtnM-2bufA:
undetectable		 1gtnL-2bufA:
15.67
1gtnM-2bufA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.15A 1jffB-4nf1A:
undetectable		 1jffB-4nf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_B_CHDB4085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.28A 1v54A-2bufA:
1.2
1v54B-2bufA:
0.0
1v54T-2bufA:
0.0		 1v54A-2bufA:
22.06
1v54B-2bufA:
21.69
1v54T-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.33A 1v54G-2bufA:
0.0
1v54N-2bufA:
0.0
1v54O-2bufA:
0.0		 1v54G-2bufA:
14.04
1v54N-2bufA:
22.06
1v54O-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.33A 1v55G-2bufA:
0.0
1v55N-2bufA:
0.0
1v55O-2bufA:
0.0		 1v55G-2bufA:
14.04
1v55N-2bufA:
22.06
1v55O-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2bty ACETYLGLUTAMATE
KINASE
(Thermotoga
maritima) 		4 / 5 GLY A  29
PRO A  64
ALA A  65
ILE A 102
 NLG  A1284 (-3.0A)
None
None
None
 0.93A 2aofA-2btyA:
undetectable		 2aofA-2btyA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.38A 2dyrG-2bufA:
0.0
2dyrN-2bufA:
0.0
2dyrO-2bufA:
0.0		 2dyrG-2bufA:
14.04
2dyrN-2bufA:
22.06
2dyrO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.34A 2eijG-2bufA:
0.0
2eijN-2bufA:
0.0
2eijO-2bufA:
0.0		 2eijG-2bufA:
14.04
2eijN-2bufA:
22.06
2eijO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.31A 2eikG-2bufA:
0.0
2eikN-2bufA:
0.0
2eikO-2bufA:
0.0		 2eikG-2bufA:
14.04
2eikN-2bufA:
22.06
2eikO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.34A 2eilG-2bufA:
0.0
2eilN-2bufA:
0.0
2eilO-2bufA:
0.0		 2eilG-2bufA:
14.04
2eilN-2bufA:
22.06
2eilO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CHDN1604_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.40A 2eimG-2bufA:
0.0
2eimN-2bufA:
0.2
2eimO-2bufA:
0.0		 2eimG-2bufA:
14.04
2eimN-2bufA:
22.06
2eimO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 2bty ACETYLGLUTAMATE
KINASE
(Thermotoga
maritima) 		3 / 3 LYS A  27
GLY A  63
PRO A  64
 NLG  A1284 (-3.4A)
NLG  A1284 ( 4.2A)
None
 0.84A 2hreB-2btyA:
undetectable		 2hreB-2btyA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.15A 2hxfB-4nf1A:
undetectable		 2hxfB-4nf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.15A 2hxhB-4nf1A:
undetectable		 2hxhB-4nf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.15A 2p4nB-4nf1A:
undetectable		 2p4nB-4nf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 2bty ACETYLGLUTAMATE
KINASE
(Thermotoga
maritima) 		5 / 9 ALA A 181
GLY A  30
GLY A  62
HIS A  60
ILE A 102
 NLG  A1284 ( 4.4A)
NLG  A1284 (-2.7A)
NLG  A1284 (-4.0A)
None
None
 1.28A 2v7bA-2btyA:
2.7		 2v7bA-2btyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 2bty ACETYLGLUTAMATE
KINASE
(Thermotoga
maritima) 		5 / 9 ALA A 181
GLY A  30
GLY A  62
HIS A  60
ILE A 102
 NLG  A1284 ( 4.4A)
NLG  A1284 (-2.7A)
NLG  A1284 (-4.0A)
None
None
 1.27A 2v7bB-2btyA:
3.4		 2v7bB-2btyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2rd5 ACETYLGLUTAMATE
KINASE-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 12 GLY A  75
GLY A  43
ASN A 117
ALA A 180
ASP A  79
 NLG  A2001 (-3.2A)
None
None
None
None
 1.27A 2vdvE-2rd5A:
3.3		 2vdvE-2rd5A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2rd5 ACETYLGLUTAMATE
KINASE-LIKE PROTEIN
(Arabidopsis
thaliana) 		5 / 11 GLY A  75
GLY A  43
ASN A 117
ALA A 180
ASP A  79
 NLG  A2001 (-3.2A)
None
None
None
None
 1.27A 2vdvF-2rd5A:
3.3		 2vdvF-2rd5A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.15A 2wbeB-4nf1A:
undetectable		 2wbeB-4nf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 2jj4 ACETYLGLUTAMATE
KINASE
(Synechococcus
elongatus) 		5 / 11 VAL A 110
VAL A 102
ARG A 109
ILE A  74
ALA A 188
 None
None
None
NLG  A1292 (-4.8A)
NLG  A1292 (-3.3A)
 1.14A 2zbzA-2jj4A:
undetectable		 2zbzA-2jj4A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.27A 2zxwA-2bufA:
undetectable
2zxwB-2bufA:
0.0
2zxwT-2bufA:
0.0		 2zxwA-2bufA:
22.06
2zxwB-2bufA:
21.69
2zxwT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.29A 3abkA-2bufA:
0.7
3abkB-2bufA:
0.0
3abkT-2bufA:
0.0		 3abkA-2bufA:
22.06
3abkB-2bufA:
21.69
3abkT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.37A 3ablA-2bufA:
0.0
3ablB-2bufA:
0.0
3ablT-2bufA:
0.0		 3ablA-2bufA:
22.06
3ablB-2bufA:
21.69
3ablT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.33A 3ag1A-2bufA:
0.0
3ag1B-2bufA:
0.0
3ag1T-2bufA:
0.0		 3ag1A-2bufA:
22.06
3ag1B-2bufA:
21.69
3ag1T-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.25A 3ag1G-2bufA:
0.0
3ag1N-2bufA:
0.0
3ag1O-2bufA:
0.0		 3ag1G-2bufA:
14.04
3ag1N-2bufA:
22.06
3ag1O-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.37A 3ag3A-2bufA:
0.0
3ag3B-2bufA:
0.0
3ag3T-2bufA:
0.0		 3ag3A-2bufA:
22.06
3ag3B-2bufA:
21.69
3ag3T-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.35A 3ag3G-2bufA:
0.0
3ag3N-2bufA:
0.0
3ag3O-2bufA:
0.0		 3ag3G-2bufA:
14.04
3ag3N-2bufA:
22.06
3ag3O-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.26A 3asnA-2bufA:
0.0
3asnB-2bufA:
0.0
3asnT-2bufA:
0.0		 3asnA-2bufA:
22.06
3asnB-2bufA:
21.69
3asnT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.27A 3asoA-2bufA:
0.0
3asoB-2bufA:
0.0
3asoT-2bufA:
0.0		 3asoA-2bufA:
22.06
3asoB-2bufA:
21.69
3asoT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.15A 3dcoB-4nf1A:
undetectable		 3dcoB-4nf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2jj4 ACETYLGLUTAMATE
KINASE
(Synechococcus
elongatus) 		4 / 7 THR A  98
VAL A 101
ILE A  74
THR A  94
 None
None
NLG  A1292 (-4.8A)
None
 0.88A 3deuA-2jj4A:
undetectable		 3deuA-2jj4A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.14A 3edlB-4nf1A:
undetectable		 3edlB-4nf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.14A 3iz0B-4nf1A:
undetectable		 3iz0B-4nf1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 3zzf ACETYLGLUTAMATE
KINASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 105
GLY A 106
PRO A 130
VAL A 188
LEU A 231
 EDO  A1355 ( 4.5A)
NLG  A1360 ( 4.9A)
None
None
None
 1.00A 3m6wA-3zzfA:
2.9		 3m6wA-3zzfA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1oh9 ACETYLGLUTAMATE
KINASE
(Escherichia
coli) 		3 / 3 LYS A  61
ARG A  66
ASP A 181
 NLG  A1260 ( 4.4A)
NLG  A1260 (-3.9A)
ADP  A1259 ( 4.9A)
 1.30A 3o7wA-1oh9A:
2.5		 3o7wA-1oh9A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 2jj4 ACETYLGLUTAMATE
KINASE
(Synechococcus
elongatus) 		5 / 11 SER A 174
ILE A 186
VAL A 136
VAL A 152
ILE A 195
 NLG  A1292 (-3.2A)
None
None
None
None
 1.17A 3rf4A-2jj4A:
undetectable
3rf4C-2jj4A:
undetectable		 3rf4A-2jj4A:
17.76
3rf4C-2jj4A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 2jj4 ACETYLGLUTAMATE
KINASE
(Synechococcus
elongatus) 		5 / 11 ILE A 195
SER A 174
ILE A 186
VAL A 136
VAL A 152
 None
NLG  A1292 (-3.2A)
None
None
None
 1.18A 3rf4B-2jj4A:
undetectable
3rf4C-2jj4A:
undetectable		 3rf4B-2jj4A:
17.76
3rf4C-2jj4A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 2rd5 ACETYLGLUTAMATE
KINASE-LIKE PROTEIN
(Arabidopsis
thaliana) 		3 / 3 ASN A  81
ALA A  91
ARG A  98
 None
None
NLG  A2001 (-4.0A)
 0.87A 3tj7C-2rd5A:
undetectable
3tj7D-2rd5A:
undetectable		 3tj7C-2rd5A:
23.47
3tj7D-2rd5A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2bty ACETYLGLUTAMATE
KINASE
(Thermotoga
maritima) 		4 / 8 LYS A  27
ILE A  26
PHE A  28
GLY A  30
 NLG  A1284 (-3.4A)
None
None
NLG  A1284 (-2.7A)
 0.86A 4hb6A-2btyA:
undetectable		 4hb6A-2btyA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2bty ACETYLGLUTAMATE
KINASE
(Thermotoga
maritima) 		4 / 8 LYS A  27
ILE A  26
PHE A  28
GLY A  30
 NLG  A1284 (-3.4A)
None
None
NLG  A1284 (-2.7A)
 0.84A 4hb8A-2btyA:
undetectable		 4hb8A-2btyA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 2bty ACETYLGLUTAMATE
KINASE
(Thermotoga
maritima) 		4 / 8 ILE A 255
ILE A  26
MET A  33
GLY A  30
 None
None
None
NLG  A1284 (-2.7A)
 0.91A 4hdlA-2btyA:
undetectable		 4hdlA-2btyA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  90
THR A  96
THR A  92
ASP A  93
 NLG  A1302 (-4.3A)
None
None
None
 1.31A 4oltA-2bufA:
undetectable		 4oltA-2bufA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  90
THR A  96
THR A  92
ASP A  93
 NLG  A1302 (-4.3A)
None
None
None
 1.26A 4oltB-2bufA:
undetectable		 4oltB-2bufA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 LEU A 353
GLY A 368
GLU A 365
ALA A 362
ALA A 340
 NLG  A 501 (-4.6A)
CL  A 503 (-3.5A)
None
None
None
 1.20A 4pclA-4nf1A:
undetectable		 4pclA-4nf1A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  90
THR A  96
THR A  92
ASP A  93
 NLG  A1302 (-4.3A)
None
None
None
 1.25A 4qwpA-2bufA:
undetectable		 4qwpA-2bufA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		4 / 5 ARG A  90
THR A  96
THR A  92
ASP A  93
 NLG  A1302 (-4.3A)
None
None
None
 1.25A 4qwpB-2bufA:
undetectable		 4qwpB-2bufA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.35A 5b1bG-2bufA:
0.0
5b1bN-2bufA:
0.0
5b1bO-2bufA:
0.0		 5b1bG-2bufA:
14.04
5b1bN-2bufA:
22.06
5b1bO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1oh9 ACETYLGLUTAMATE
KINASE
(Escherichia
coli) 		5 / 12 ALA A 161
GLY A  43
GLY A  11
LEU A  13
ALA A  81
 NLG  A1260 ( 3.2A)
NLG  A1260 ( 3.5A)
ADP  A1259 ( 3.8A)
None
None
 0.93A 5c0oG-1oh9A:
2.7		 5c0oG-1oh9A:
24.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3zzf ACETYLGLUTAMATE
KINASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 255
ILE A 313
LEU A 317
ILE A 266
GLY A 135
 None
None
None
EDO  A1354 (-4.7A)
NLG  A1360 (-3.2A)
 0.97A 5d4uC-3zzfA:
undetectable		 5d4uC-3zzfA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3zzf ACETYLGLUTAMATE
KINASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 255
ILE A 313
LEU A 317
ILE A 266
GLY A 135
 None
None
None
EDO  A1354 (-4.7A)
NLG  A1360 (-3.2A)
 0.95A 5d4uD-3zzfA:
undetectable		 5d4uD-3zzfA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2rd5 ACETYLGLUTAMATE
KINASE-LIKE PROTEIN
(Arabidopsis
thaliana) 		4 / 7 ASN A 192
VAL A 182
SER A 181
ALA A 180
 NLG  A2001 (-2.8A)
None
NLG  A2001 ( 4.2A)
None
 0.81A 5fpdB-2rd5A:
undetectable		 5fpdB-2rd5A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.08A 5hnwB-4nf1A:
undetectable		 5hnwB-4nf1A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4nf1 ACETYLGLUTAMATE
KINASE
(Xylella
fastidiosa) 		5 / 12 VAL A 334
LEU A 436
LEU A 319
THR A 318
ARG A 316
 None
NLG  A 501 ( 4.7A)
None
None
None
 1.13A 5hnyB-4nf1A:
undetectable		 5hnyB-4nf1A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.39A 5x1fG-2bufA:
0.0
5x1fN-2bufA:
0.0
5x1fO-2bufA:
0.0		 5x1fG-2bufA:
14.04
5x1fN-2bufA:
22.06
5x1fO-2bufA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 2bty ACETYLGLUTAMATE
KINASE
(Thermotoga
maritima) 		4 / 5 PHE A  28
THR A 201
ASP A 182
ASN A 178
 None
None
NLG  A1284 (-3.4A)
None
 1.49A 5ybbA-2btyA:
1.0		 5ybbA-2btyA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 3zzf ACETYLGLUTAMATE
KINASE
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 237
ALA A 250
ASP A 251
GLY A 106
ILE A 109
VAL A 168
 None
NLG  A1360 (-3.3A)
None
NLG  A1360 ( 4.9A)
None
None
 1.48A 6dilA-3zzfA:
undetectable		 6dilA-3zzfA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  67
GLN A  71
GLU A  40
ARG A  90
GLY A 105
 NLG  A1302 (-3.3A)
None
None
NLG  A1302 (-4.3A)
None
 1.45A 6nknA-2bufA:
0.0
6nknB-2bufA:
0.0
6nknT-2bufA:
0.0		 6nknA-2bufA:
22.06
6nknB-2bufA:
21.69
6nknT-2bufA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2buf ACETYLGLUTAMATE
KINASE
(Pseudomonas
aeruginosa) 		5 / 10 ARG A  90
GLY A 105
GLY A  67
GLN A  71
GLU A  40
 NLG  A1302 (-4.3A)
None
NLG  A1302 (-3.3A)
None
None
 1.39A 6nmfG-2bufA:
0.0
6nmfN-2bufA:
0.0
6nmfO-2bufA:
0.0		 6nmfG-2bufA:
14.04
6nmfN-2bufA:
22.06
6nmfO-2bufA:
21.69