SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NLA'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NVC_A_SALA370_1 (GENTISATE 1,2-DIOXYGENASE)	1lrh	AUXIN-BINDING PROTEIN 1 (Zea mays)	4 / 6	GLN A 46 HIS A 57 HIS A 59 HIS A 106	NLA A5190 (-3.1A) ZN A 180 ( 3.4A) ZN A 180 ( 3.5A) ZN A 180 (-3.3A)	1.10A	3nvcA-1lrhA: 10.6	3nvcA-1lrhA: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NVC_A_SALA370_1 (GENTISATE 1,2-DIOXYGENASE)	1lrh	AUXIN-BINDING PROTEIN 1 (Zea mays)	4 / 6	GLN A 46 HIS A 59 HIS A 106 HIS A 57	NLA A5190 (-3.1A) ZN A 180 ( 3.5A) ZN A 180 (-3.3A) ZN A 180 ( 3.4A)	1.16A	3nvcA-1lrhA: 10.6	3nvcA-1lrhA: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_D_CLMD221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	1lrh	AUXIN-BINDING PROTEIN 1 (Zea mays)	5 / 12	THR A 54 VAL A 121 ALA A 128 CYH A 61 HIS A 59	NLA A5190 (-4.2A) None None None ZN A 180 ( 3.5A)	1.30A	3u9fD-1lrhA: 0.0 3u9fE-1lrhA: 0.0	3u9fD-1lrhA: 18.92 3u9fE-1lrhA: 18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_G_CLMG221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	1lrh	AUXIN-BINDING PROTEIN 1 (Zea mays)	5 / 12	THR A 54 VAL A 121 ALA A 128 CYH A 61 HIS A 59	NLA A5190 (-4.2A) None None None ZN A 180 ( 3.5A)	1.24A	3u9fG-1lrhA: 0.0 3u9fH-1lrhA: 0.0	3u9fG-1lrhA: 18.92 3u9fH-1lrhA: 18.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3NVC_A_SALA370_1","GENTISATE 1,2-DIOXYGENASE","1lrh","AUXIN-BINDING PROTEIN 1","Zea mays",4,"GLN A  46;HIS A  57;HIS A  59;HIS A 106","NLA A5190 (-3.1A); ZN A 180 ( 3.4A); ZN A 180 ( 3.5A); ZN A 180 (-3.3A)","1.10A","3nvcA-1lrhA:10.6",null],["3NVC_A_SALA370_1","GENTISATE 1,2-DIOXYGENASE","1lrh","AUXIN-BINDING PROTEIN 1","Zea mays",4,"GLN A  46;HIS A  59;HIS A 106;HIS A  57","NLA A5190 (-3.1A); ZN A 180 ( 3.5A); ZN A 180 (-3.3A); ZN A 180 ( 3.4A)","1.16A","3nvcA-1lrhA:10.6","3nvcA-1lrhA:19.02"],["3U9F_D_CLMD221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","1lrh","AUXIN-BINDING PROTEIN 1","Zea mays",5,"THR A  54;VAL A 121;ALA A 128;CYH A  61;HIS A  59","NLA A5190 (-4.2A);None;None;None; ZN A 180 ( 3.5A)","1.30A","3u9fD-1lrhA:0.0;3u9fE-1lrhA:0.0","3nvcA-1lrhA:19.02"],["3U9F_G_CLMG221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","1lrh","AUXIN-BINDING PROTEIN 1","Zea mays",5,"THR A  54;VAL A 121;ALA A 128;CYH A  61;HIS A  59","NLA A5190 (-4.2A);None;None;None; ZN A 180 ( 3.5A)","1.24A","3u9fG-1lrhA:0.0;3u9fH-1lrhA:0.0","3u9fD-1lrhA:18.92;3u9fE-1lrhA:18.92"]]