SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NIL'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1MX1_F_THAF6_1 (LIVERCARBOXYLESTERASE I) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 12 | VAL A 102LEU A 55LEU A 75LEU A 104LEU A 74 | NoneNoneNIL A 1 ( 4.8A)NIL A 1 ( 4.3A)None | 0.94A | 1mx1F-3gp0A:undetectable | 1mx1F-3gp0A:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWH_A_BAXA1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 12 | ALA A 51GLU A 71LEU A 75THR A 106HIS A 148 | NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A)NIL A 1 (-4.3A) | 0.51A | 1uwhA-3gp0A:22.5 | 1uwhA-3gp0A:27.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWH_B_BAXB1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | ALA A 51LYS A 53GLU A 71LEU A 75THR A 106HIS A 148 | NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A)NIL A 1 (-4.3A) | 0.67A | 1uwhB-3gp0A:22.5 | 1uwhB-3gp0A:27.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UWJ_A_BAXA1723_1 (B-RAF PROTO-ONCOGENESERINE/THREONINE-PROTEIN KINASE) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 12 | VAL A 38ALA A 51GLU A 71THR A 106HIS A 148 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 (-3.3A)NIL A 1 (-4.3A) | 0.53A | 1uwjA-3gp0A:5.6 | 1uwjA-3gp0A:27.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1XKK_A_FMMA91_2 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 9 | VAL A 38LEU A 86LEU A 104LEU A 108MET A 109 | NIL A 1 ( 4.7A)NoneNIL A 1 ( 4.3A)NIL A 1 ( 4.4A)None | 0.63A | 1xkkA-3gp0A:20.5 | 1xkkA-3gp0A:25.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1XKK_A_FMMA91_2 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 9 | VAL A 38LYS A 53LEU A 86LEU A 104LEU A 108 | NIL A 1 ( 4.7A)NoneNoneNIL A 1 ( 4.3A)NIL A 1 ( 4.4A) | 0.67A | 1xkkA-3gp0A:20.5 | 1xkkA-3gp0A:25.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CS9_B_NILB600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 12 | ALA A 51GLU A 71THR A 106HIS A 148ASP A 168 | NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 (-3.3A)NIL A 1 (-4.3A)NIL A 1 (-4.6A) | 0.36A | 3cs9B-3gp0A:22.5 | 3cs9B-3gp0A:25.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CS9_C_NILC600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 12 | ALA A 51GLU A 71THR A 106HIS A 148ASP A 168 | NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 (-3.3A)NIL A 1 (-4.3A)NIL A 1 (-4.6A) | 0.29A | 3cs9C-3gp0A:22.3 | 3cs9C-3gp0A:25.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GCS_A_BAXA401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 8 / 12 | ALA A 51GLU A 71LEU A 75THR A 106ILE A 141HIS A 148LEU A 167ASP A 168 | NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.3A)NIL A 1 (-4.0A)NIL A 1 (-4.6A) | 0.79A | 3gcsA-3gp0A:40.6 | 3gcsA-3gp0A:74.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GCS_A_BAXA401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 12 | ALA A 51LEU A 74LEU A 75THR A 106ILE A 141HIS A 148ASP A 168 | NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.3A)NIL A 1 (-4.6A) | 0.76A | 3gcsA-3gp0A:40.6 | 3gcsA-3gp0A:74.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GCS_A_BAXA401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 8 / 12 | ALA A 51LEU A 75ILE A 84THR A 106ILE A 141HIS A 148LEU A 167ASP A 168 | NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.3A)NIL A 1 (-4.0A)NIL A 1 (-4.6A) | 0.80A | 3gcsA-3gp0A:40.6 | 3gcsA-3gp0A:74.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3GCS_A_BAXA401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 12 | VAL A 38ALA A 51LEU A 74LEU A 75THR A 106 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-3.3A) | 0.61A | 3gcsA-3gp0A:40.6 | 3gcsA-3gp0A:74.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3H5G_B_LEIB16_0 (COIL SER L16D-PEN) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 4 / 5 | LEU A 104LYS A 76LEU A 72GLU A 71 | NIL A 1 ( 4.3A)NoneNoneNIL A 1 (-3.7A) | 1.12A | 3h5gA-3gp0A:undetectable3h5gB-3gp0A:undetectable | 3h5gA-3gp0A:7.543h5gB-3gp0A:7.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEC_A_STIA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 9 / 12 | ALA A 51GLU A 71LEU A 74LEU A 75THR A 106LEU A 108LEU A 167ASP A 168PHE A 169 | NIL A 1 (-3.7A)NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-3.3A)NIL A 1 ( 4.4A)NIL A 1 (-4.0A)NIL A 1 (-4.6A)NIL A 1 (-3.5A) | 0.70A | 3hecA-3gp0A:41.8 | 3hecA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEC_A_STIA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 8 / 12 | ALA A 51GLU A 71LEU A 75ILE A 84THR A 106LEU A 167ASP A 168PHE A 169 | NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NIL A 1 (-4.0A)NIL A 1 (-4.6A)NIL A 1 (-3.5A) | 0.67A | 3hecA-3gp0A:41.8 | 3hecA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEC_A_STIA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | ALA A 51LEU A 78LEU A 75ILE A 84THR A 106LEU A 167 | NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NIL A 1 (-4.0A) | 1.49A | 3hecA-3gp0A:41.8 | 3hecA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEC_A_STIA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | ALA A 51LYS A 53THR A 106LEU A 108LEU A 167ASP A 168 | NIL A 1 (-3.7A)NoneNIL A 1 (-3.3A)NIL A 1 ( 4.4A)NIL A 1 (-4.0A)NIL A 1 (-4.6A) | 0.73A | 3hecA-3gp0A:41.8 | 3hecA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEC_A_STIA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 9 / 12 | VAL A 30ALA A 51GLU A 71LEU A 74LEU A 75THR A 106LEU A 108ASP A 168PHE A 169 | NoneNIL A 1 (-3.7A)NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-3.3A)NIL A 1 ( 4.4A)NIL A 1 (-4.6A)NIL A 1 (-3.5A) | 0.82A | 3hecA-3gp0A:41.8 | 3hecA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEC_A_STIA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 30ALA A 51LYS A 53THR A 106LEU A 108ASP A 168 | NoneNIL A 1 (-3.7A)NoneNIL A 1 (-3.3A)NIL A 1 ( 4.4A)NIL A 1 (-4.6A) | 0.61A | 3hecA-3gp0A:41.8 | 3hecA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | ALA A 51GLU A 71LEU A 75THR A 106ILE A 141ASP A 168 | NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.6A) | 0.73A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | ALA A 51LEU A 74LEU A 75THR A 106ILE A 141ASP A 168 | NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.6A) | 0.75A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | ALA A 51LEU A 75ILE A 84THR A 106ILE A 141ASP A 168 | NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.6A) | 0.71A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | ALA A 51LYS A 53GLU A 71THR A 106ILE A 141ASP A 168 | NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.6A) | 1.06A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | ALA A 51LYS A 53ILE A 84THR A 106ILE A 141ASP A 168 | NIL A 1 (-3.7A)NoneNIL A 1 (-4.4A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.6A) | 1.08A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 30VAL A 38ALA A 51GLU A 71LEU A 75THR A 106 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A) | 0.84A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 30VAL A 38ALA A 51LEU A 74LEU A 75THR A 106 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-3.3A) | 0.66A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51GLU A 71LEU A 75THR A 106ILE A 141 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A)None | 0.94A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51LEU A 74LEU A 75THR A 106ILE A 141 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-3.3A)None | 0.91A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51LEU A 75ILE A 84THR A 106ILE A 141 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)None | 0.95A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3HEG_A_BAXA1_2 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 6 | VAL A 83ILE A 146HIS A 148ILE A 166LEU A 167 | NIL A 1 (-4.9A)NoneNIL A 1 (-4.3A)NIL A 1 ( 4.9A)NIL A 1 (-4.0A) | 0.43A | 3hegA-3gp0A:42.4 | 3hegA-3gp0A:75.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3LFA_A_1N1A361_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 8 | VAL A 30ALA A 51GLU A 71LEU A 104LEU A 108MET A 109 | NoneNIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.3A)NIL A 1 ( 4.4A)None | 0.72A | 3lfaA-3gp0A:40.5 | 3lfaA-3gp0A:75.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3LFA_A_1N1A361_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 8 | VAL A 30ALA A 51GLU A 71LEU A 104THR A 106LEU A 108 | NoneNIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.3A)NIL A 1 (-3.3A)NIL A 1 ( 4.4A) | 0.50A | 3lfaA-3gp0A:40.5 | 3lfaA-3gp0A:75.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_A_1N1A1000_1 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 8 / 12 | GLY A 31VAL A 38ALA A 51LEU A 75ILE A 84THR A 106ASN A 114LEU A 167 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.0A) | 1.19A | 3ohtA-3gp0A:33.1 | 3ohtA-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_A_1N1A1000_1 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 9 / 12 | GLY A 31VAL A 38ALA A 51LYS A 53LEU A 75ILE A 84THR A 106ASN A 115LEU A 167 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.0A) | 1.04A | 3ohtA-3gp0A:33.1 | 3ohtA-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_A_1N1A1000_1 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 8 / 12 | VAL A 30GLY A 31VAL A 38ALA A 51LEU A 75THR A 106ASN A 114LEU A 167 | NoneNoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.0A) | 1.15A | 3ohtA-3gp0A:33.1 | 3ohtA-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_A_1N1A1000_1 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 8 / 12 | VAL A 30GLY A 31VAL A 38ALA A 51LEU A 75THR A 106ASN A 115LEU A 167 | NoneNoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.0A) | 1.15A | 3ohtA-3gp0A:33.1 | 3ohtA-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_A_1N1A1000_1 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 8 / 12 | VAL A 38ALA A 51LYS A 53ILE A 84THR A 106ASN A 115LEU A 167PHE A 169 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 (-4.4A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.0A)NIL A 1 (-3.5A) | 1.16A | 3ohtA-3gp0A:33.1 | 3ohtA-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_A_1N1A1000_2 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 3 / 3 | GLU A 71LEU A 104LEU A 108 | NIL A 1 (-3.7A)NIL A 1 ( 4.3A)NIL A 1 ( 4.4A) | 0.34A | 3ohtA-3gp0A:33.1 | 3ohtA-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_B_1N1B1000_1 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 12 | GLY A 31VAL A 38ALA A 51LEU A 75ILE A 84THR A 106ASN A 114 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)None | 1.20A | 3ohtB-3gp0A:32.9 | 3ohtB-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_B_1N1B1000_1 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 12 | GLY A 31VAL A 38ALA A 51LEU A 75ILE A 84THR A 106LEU A 167 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NIL A 1 (-4.0A) | 0.73A | 3ohtB-3gp0A:32.9 | 3ohtB-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_B_1N1B1000_1 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 8 / 12 | GLY A 31VAL A 38ALA A 51LYS A 53ILE A 84THR A 106ASN A 115LEU A 167 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 (-4.4A)NIL A 1 (-3.3A)NoneNIL A 1 (-4.0A) | 1.02A | 3ohtB-3gp0A:32.9 | 3ohtB-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3OHT_B_1N1B1000_2 (P38A) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 3 / 3 | GLU A 71LEU A 104LEU A 108 | NIL A 1 (-3.7A)NIL A 1 ( 4.3A)NIL A 1 ( 4.4A) | 0.33A | 3ohtB-3gp0A:32.9 | 3ohtB-3gp0A:68.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3RGF_A_BAXA465_1 (CYCLIN-DEPENDENTKINASE 8) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51GLU A 71LEU A 75ILE A 84HIS A 148 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-4.4A)NIL A 1 (-4.3A) | 0.51A | 3rgfA-3gp0A:10.0 | 3rgfA-3gp0A:30.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3RGF_A_BAXA465_2 (CYCLIN-DEPENDENTKINASE 8) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 4 / 7 | LYS A 53LEU A 78VAL A 83ASP A 168 | NoneNoneNIL A 1 (-4.9A)NIL A 1 (-4.6A) | 0.25A | 3rgfA-3gp0A:8.5 | 3rgfA-3gp0A:30.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZOS_B_0LIB1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 12 | ALA A 51LYS A 53GLU A 71ILE A 84THR A 106HIS A 148ASP A 168 | NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NIL A 1 (-4.3A)NIL A 1 (-4.6A) | 0.74A | 3zosB-3gp0A:22.0 | 3zosB-3gp0A:25.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_A_STIA1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51GLU A 71ILE A 84THR A 106ASP A 168 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NIL A 1 (-4.6A) | 0.52A | 4bkjA-3gp0A:22.2 | 4bkjA-3gp0A:25.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_B_STIB1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51GLU A 71ILE A 84THR A 106ASP A 168 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)NIL A 1 (-4.6A) | 0.47A | 4bkjB-3gp0A:22.2 | 4bkjB-3gp0A:25.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C8B_A_0LIA1000_1 (RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 12 | ALA A 51LYS A 53GLU A 71LEU A 75THR A 106HIS A 148ASP A 168 | NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A)NIL A 1 (-4.3A)NIL A 1 (-4.6A) | 0.77A | 4c8bA-3gp0A:21.8 | 4c8bA-3gp0A:25.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C8B_B_0LIB1000_1 (RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 12 | ALA A 51LYS A 53GLU A 71LEU A 75THR A 106HIS A 148ASP A 168 | NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 ( 4.8A)NIL A 1 (-3.3A)NIL A 1 (-4.3A)NIL A 1 (-4.6A) | 0.71A | 4c8bB-3gp0A:22.0 | 4c8bB-3gp0A:25.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4I41_A_MIXA500_1 (SERINE/THREONINE-PROTEIN KINASE PIM-1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 12 | VAL A 38ALA A 51ILE A 84ASP A 112ASP A 150LYS A 152ASN A 155 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-4.4A)NoneNoneNoneNone | 0.71A | 4i41A-3gp0A:21.4 | 4i41A-3gp0A:26.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4R7I_A_STIA1001_1 (MACROPHAGECOLONY-STIMULATINGFACTOR 1 RECEPTOR) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51GLU A 71THR A 106ASP A 168PHE A 169 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 (-3.3A)NIL A 1 (-4.6A)NIL A 1 (-3.5A) | 0.71A | 4r7iA-3gp0A:22.2 | 4r7iA-3gp0A:26.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RZ7_A_1E8A901_1 (CGMP-DEPENDENTPROTEIN KINASE,PUTATIVE) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 10 | ALA A 51LYS A 53ILE A 84THR A 106LEU A 108 | NIL A 1 (-3.7A)NoneNIL A 1 (-4.4A)NIL A 1 (-3.3A)NIL A 1 ( 4.4A) | 0.55A | 4rz7A-3gp0A:8.0 | 4rz7A-3gp0A:15.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4U0I_A_0LIA1001_2 (MAST/STEM CELLGROWTH FACTORRECEPTORKIT,MAST/STEM CELLGROWTH FACTORRECEPTOR KIT) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 12 | ALA A 51LYS A 53LEU A 75THR A 106HIS A 148ASP A 168PHE A 169 | NIL A 1 (-3.7A)NoneNIL A 1 ( 4.8A)NIL A 1 (-3.3A)NIL A 1 (-4.3A)NIL A 1 (-4.6A)NIL A 1 (-3.5A) | 1.02A | 4u0iA-3gp0A:22.2 | 4u0iA-3gp0A:26.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4UXQ_A_0LIA1752_2 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 4 / 7 | VAL A 38LYS A 53ILE A 84ILE A 166 | NIL A 1 ( 4.7A)NoneNIL A 1 (-4.4A)NIL A 1 ( 4.9A) | 0.33A | 4uxqA-3gp0A:22.9 | 4uxqA-3gp0A:29.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5FSA_A_X2NA590_2 (CYP51 VARIANT1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 3 / 3 | PRO A 58ILE A 84SER A 100 | NoneNIL A 1 (-4.4A)None | 0.67A | 5fsaA-3gp0A:undetectable | 5fsaA-3gp0A:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5H2U_A_1N1A501_1 (PROTEIN-TYROSINEKINASE 6) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | ARG A 28VAL A 38ALA A 51THR A 106LEU A 108LEU A 167 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-3.3A)NIL A 1 ( 4.4A)NIL A 1 (-4.0A) | 1.12A | 5h2uA-3gp0A:20.5 | 5h2uA-3gp0A:26.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5LW1_B_ADNB401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 8) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 9 | GLY A 31VAL A 38ALA A 51ILE A 84MET A 109LEU A 167 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-4.4A)NoneNIL A 1 (-4.0A) | 0.89A | 5lw1B-3gp0A:37.6 | 5lw1B-3gp0A:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5LW1_E_ADNE401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 8) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 10 | GLY A 31VAL A 38ALA A 51ILE A 84LEU A 108MET A 109LEU A 167 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-4.4A)NIL A 1 ( 4.4A)NoneNIL A 1 (-4.0A) | 0.83A | 5lw1E-3gp0A:37.2 | 5lw1E-3gp0A:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5LW1_H_ADNH401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 8) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 9 | GLY A 31VAL A 38ALA A 51LEU A 108MET A 109LEU A 167 | NoneNIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.4A)NoneNIL A 1 (-4.0A) | 0.79A | 5lw1H-3gp0A:37.5 | 5lw1H-3gp0A:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VCY_A_DB8A401_1 (MEMBRANE-ASSOCIATEDTYROSINE- ANDTHREONINE-SPECIFICCDC2-INHIBITORYKINASE) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51GLU A 71LEU A 104THR A 106GLY A 110 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NIL A 1 (-3.7A)NIL A 1 ( 4.3A)NIL A 1 (-3.3A)None | 0.73A | 5vcyA-3gp0A:22.6 | 5vcyA-3gp0A:25.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VCY_A_DB8A401_1 (MEMBRANE-ASSOCIATEDTYROSINE- ANDTHREONINE-SPECIFICCDC2-INHIBITORYKINASE) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51LYS A 53GLU A 71THR A 106GLY A 110 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 (-3.3A)None | 0.84A | 5vcyA-3gp0A:22.6 | 5vcyA-3gp0A:25.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XXI_A_LSNA501_1 (CYTOCHROME P450 2C9) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 5 / 12 | ALA A 299VAL A 83VAL A 209LEU A 74LEU A 78 | NoneNIL A 1 (-4.9A)NoneNoneNone | 1.07A | 5xxiA-3gp0A:undetectable | 5xxiA-3gp0A:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6BSD_A_1N1A901_0 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 7 / 12 | VAL A 38ALA A 51LYS A 53GLU A 71ILE A 84THR A 106MET A 109 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 (-4.4A)NIL A 1 (-3.3A)None | 0.69A | 6bsdA-3gp0A:21.4 | 6bsdA-3gp0A:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_A_STIA604_0 (TYROSINE-PROTEINKINASE ABL1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51LYS A 53GLU A 71THR A 106ASP A 168 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 (-3.3A)NIL A 1 (-4.6A) | 0.53A | 6hd4A-3gp0A:21.9 | 6hd4A-3gp0A:13.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD4_B_STIB602_0 (TYROSINE-PROTEINKINASE ABL1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51LYS A 53GLU A 71THR A 106ASP A 168 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 (-3.3A)NIL A 1 (-4.6A) | 0.58A | 6hd4B-3gp0A:21.8 | 6hd4B-3gp0A:13.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HD6_B_STIB601_0 (TYROSINE-PROTEINKINASE ABL1) |
3gp0 | MITOGEN-ACTIVATEDPROTEIN KINASE 11 (Homosapiens) | 6 / 12 | VAL A 38ALA A 51LYS A 53GLU A 71THR A 106ASP A 168 | NIL A 1 ( 4.7A)NIL A 1 (-3.7A)NoneNIL A 1 (-3.7A)NIL A 1 (-3.3A)NIL A 1 (-4.6A) | 0.53A | 6hd6B-3gp0A:21.8 | 6hd6B-3gp0A:13.26 |