SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NH3'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 12 LEU A 114
GLY A  27
ALA A  29
GLY A  34
LEU A  35
 NH3  A 403 ( 4.6A)
None
None
None
None
 1.05A 1fe2A-1u7gA:
undetectable		 1fe2A-1u7gA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		4 / 7 GLY A 319
HIS A 168
THR A 362
ILE A 323
 None
NH3  A 402 ( 4.1A)
None
None
 0.97A 1gtnF-1u7gA:
undetectable
1gtnG-1u7gA:
undetectable		 1gtnF-1u7gA:
11.47
1gtnG-1u7gA:
11.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 1u0x NITROPHORIN 4
(Rhodnius
prolixus) 		3 / 3 ASP A  30
LEU A 123
LEU A 133
 None
HEM  A 185 (-4.4A)
NH3  A 186 ( 4.8A)
 0.37A 1ikeA-1u0xA:
35.9		 1ikeA-1u0xA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 1u0x NITROPHORIN 4
(Rhodnius
prolixus) 		4 / 5 ASP A  30
GLU A  32
LEU A 123
LEU A 133
 None
None
HEM  A 185 (-4.4A)
NH3  A 186 ( 4.8A)
 0.79A 1np1A-1u0xA:
32.1		 1np1A-1u0xA:
90.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 1u0x NITROPHORIN 4
(Rhodnius
prolixus) 		3 / 3 ASP A  30
LEU A 123
LEU A 133
 None
HEM  A 185 (-4.4A)
NH3  A 186 ( 4.8A)
 0.41A 1np1B-1u0xA:
31.9		 1np1B-1u0xA:
90.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		3 / 3 ALA A 265
VAL A 270
TRP A 212
 None
None
NH3  A 402 ( 3.7A)
 0.82A 1nt5A-1u7gA:
undetectable		 1nt5A-1u7gA:
4.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		3 / 3 ALA A 265
VAL A 270
TRP A 212
 None
None
NH3  A 402 ( 3.7A)
 0.82A 1nt5B-1u7gA:
undetectable		 1nt5B-1u7gA:
4.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 4 HIS A 216
VAL A 146
THR A  61
LEU A  65
 None
None
NH3  A 504 ( 2.8A)
None
 1.21A 1oq5A-5msyA:
undetectable		 1oq5A-5msyA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 8 ILE A  28
ILE A 110
GLY A 211
ILE A 210
PRO A  26
 None
NH3  A 402 ( 4.8A)
None
None
None
 1.18A 1sh9A-1u7gA:
undetectable		 1sh9A-1u7gA:
14.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1u0x NITROPHORIN 4
(Rhodnius
prolixus) 		5 / 5 ASP A  30
GLU A  32
THR A 121
LEU A 123
LEU A 133
 None
None
HEM  A 185 ( 4.3A)
HEM  A 185 (-4.4A)
NH3  A 186 ( 4.8A)
 0.91A 1u18B-1u0xA:
31.5		 1u18B-1u0xA:
89.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A 102
LEU A  65
ALA A  74
GLU A  73
 NH3  A 509 (-4.0A)
None
None
None
 1.22A 1xvaA-5msyA:
undetectable
1xvaB-5msyA:
undetectable		 1xvaA-5msyA:
20.17
1xvaB-5msyA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 9 PHE A  31
TYR A  32
GLY A 316
VAL A 270
ILE A 266
 NH3  A 401 ( 4.3A)
None
None
None
NH3  A 401 (-3.9A)
 1.04A 2a1oB-1u7gA:
undetectable		 2a1oB-1u7gA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 GLU A 284
PRO A 285
ILE A 286
GLY A 241
 NH3  A 504 (-4.4A)
None
None
None
 0.80A 2qeuA-5msyA:
undetectable
2qeuC-5msyA:
undetectable		 2qeuA-5msyA:
14.97
2qeuC-5msyA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 GLY A  59
GLY A 144
PHE A 235
PHE A 320
 None
None
None
NH3  A 506 ( 4.9A)
 1.02A 2qx6A-5msyA:
undetectable
2qx6B-5msyA:
undetectable		 2qx6A-5msyA:
19.35
2qx6B-5msyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 12 ILE A 266
LEU A  35
ALA A 118
ILE A 110
MET A  23
 NH3  A 401 (-3.9A)
None
None
NH3  A 402 ( 4.8A)
NH3  A 402 (-4.4A)
 1.12A 3b2rA-1u7gA:
undetectable		 3b2rA-1u7gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 11 ILE A 266
LEU A  35
ALA A 118
ILE A 110
MET A  23
 NH3  A 401 (-3.9A)
None
None
NH3  A 402 ( 4.8A)
NH3  A 402 (-4.4A)
 1.07A 3b2rB-1u7gA:
undetectable		 3b2rB-1u7gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 11 PHE A 193
LEU A  35
ASP A 313
PHE A  31
LEU A 259
 None
None
BOG  A 400 (-4.7A)
NH3  A 401 ( 4.3A)
BOG  A 400 (-4.3A)
 1.45A 3o94A-1u7gA:
undetectable		 3o94A-1u7gA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 11 PHE A 193
LEU A  35
ASP A 313
PHE A  31
LEU A 259
 None
None
BOG  A 400 (-4.7A)
NH3  A 401 ( 4.3A)
BOG  A 400 (-4.3A)
 1.50A 3o94B-1u7gA:
undetectable		 3o94B-1u7gA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 11 PHE A 193
LEU A  35
ASP A 313
PHE A  31
LEU A 259
 None
None
BOG  A 400 (-4.7A)
NH3  A 401 ( 4.3A)
BOG  A 400 (-4.3A)
 1.47A 3o94C-1u7gA:
undetectable		 3o94C-1u7gA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 11 PHE A 193
LEU A  35
ASP A 313
PHE A  31
LEU A 259
 None
None
BOG  A 400 (-4.7A)
NH3  A 401 ( 4.3A)
BOG  A 400 (-4.3A)
 1.46A 3o94D-1u7gA:
undetectable		 3o94D-1u7gA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ASN A 236
ASP A 282
THR A  61
SER A 223
 None
None
NH3  A 504 ( 2.8A)
None
 1.31A 3p2kC-5msyA:
undetectable		 3p2kC-5msyA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A 282
GLU A 284
GLY A 241
 None
NH3  A 504 (-4.4A)
None
 0.71A 3w9tA-5msyA:
undetectable		 3w9tA-5msyA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 HIS A 322
GLY A 283
HIS A 242
GLY A 325
TYR A 287
 None
None
None
NH3  A 505 (-3.5A)
NH3  A 504 (-4.4A)
 1.21A 4bz6C-5msyA:
undetectable		 4bz6C-5msyA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 5 THR A 135
LEU A  78
THR A  61
MET A 330
 None
None
NH3  A 504 ( 2.8A)
None
 1.47A 4mbsB-5msyA:
undetectable		 4mbsB-5msyA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 10 TYR A  32
LEU A  35
LEU A 114
LEU A 208
LEU A 259
 None
None
NH3  A 403 ( 4.6A)
NH3  A 401 (-4.5A)
BOG  A 400 (-4.3A)
 0.88A 4odoA-1u7gA:
undetectable		 4odoA-1u7gA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 10 TYR A  32
LEU A  35
LEU A 114
LEU A 208
LEU A 259
 None
None
NH3  A 403 ( 4.6A)
NH3  A 401 (-4.5A)
BOG  A 400 (-4.3A)
 0.88A 4odoB-1u7gA:
undetectable		 4odoB-1u7gA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 10 TYR A  32
LEU A  35
LEU A 114
LEU A 208
LEU A 259
 None
None
NH3  A 403 ( 4.6A)
NH3  A 401 (-4.5A)
BOG  A 400 (-4.3A)
 0.88A 4odoC-1u7gA:
undetectable		 4odoC-1u7gA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PHE A 235
PHE A 320
PHE A  56
GLY A  59
 None
NH3  A 506 ( 4.9A)
None
None
 1.00A 4qoiA-5msyA:
undetectable
4qoiB-5msyA:
undetectable		 4qoiA-5msyA:
19.31
4qoiB-5msyA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 12 TYR A 374
GLY A 373
PHE A 215
GLY A 163
THR A 165
 None
None
NH3  A 402 (-3.4A)
None
None
 1.16A 5fsaB-1u7gA:
undetectable		 5fsaB-1u7gA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		6 / 12 GLY A 322
HIS A 318
VAL A 317
ILE A 286
MET A 328
VAL A 290
 None
NH3  A 401 ( 3.9A)
None
None
None
None
 1.48A 5n0sA-1u7gA:
undetectable		 5n0sA-1u7gA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		6 / 12 GLY A 322
HIS A 318
VAL A 317
ILE A 286
MET A 328
VAL A 290
 None
NH3  A 401 ( 3.9A)
None
None
None
None
 1.44A 5n0tA-1u7gA:
undetectable		 5n0tA-1u7gA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		6 / 12 GLY A 322
HIS A 318
VAL A 317
ILE A 286
MET A 328
VAL A 290
 None
NH3  A 401 ( 3.9A)
None
None
None
None
 1.46A 5n0wB-1u7gA:
undetectable		 5n0wB-1u7gA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 12 GLY A 322
HIS A 318
ILE A 286
MET A 328
VAL A 290
 None
NH3  A 401 ( 3.9A)
None
None
None
 1.12A 5n0xA-1u7gA:
undetectable		 5n0xA-1u7gA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		6 / 12 GLY A 322
HIS A 318
VAL A 317
ILE A 286
MET A 328
VAL A 290
 None
NH3  A 401 ( 3.9A)
None
None
None
None
 1.48A 5n4iA-1u7gA:
undetectable		 5n4iA-1u7gA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 12 LEU A  45
PHE A  31
GLY A  27
ILE A  25
HIS A 318
 None
NH3  A 401 ( 4.3A)
None
None
NH3  A 401 ( 3.9A)
 1.11A 5y2tA-1u7gA:
undetectable		 5y2tA-1u7gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 144
GLN A  90
LEU A  78
ILE A 133
MET A 129
 None
NH3  A 504 ( 4.4A)
None
None
None
 0.72A 5y2tA-5msyA:
undetectable		 5y2tA-5msyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		6 / 12 LEU A 170
GLY A 144
GLN A  90
TYR A  77
LEU A  78
ILE A 133
 None
None
NH3  A 504 ( 4.4A)
None
None
None
 1.10A 5y2tA-5msyA:
undetectable		 5y2tA-5msyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5msy GLYCOSIDE HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 LEU A 170
GLN A  90
TYR A  77
LEU A  78
ILE A 133
 None
NH3  A 504 ( 4.4A)
None
None
None
 1.16A 5y2tB-5msyA:
undetectable		 5y2tB-5msyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		4 / 5 VAL A  60
PHE A  22
MET A  23
GLY A  27
 None
None
NH3  A 402 (-4.4A)
None
 1.41A 6hd4A-1u7gA:
undetectable		 6hd4A-1u7gA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1u7g PROBABLE AMMONIUM
TRANSPORTER
(Escherichia
coli) 		5 / 12 PHE A  31
GLY A  27
HIS A 168
ILE A  25
HIS A 318
 NH3  A 401 ( 4.3A)
None
NH3  A 402 ( 4.1A)
None
NH3  A 401 ( 3.9A)
 1.15A 6md4A-1u7gA:
0.0		 6md4A-1u7gA:
9.92