SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NGQ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 (-3.3A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.51A 1a4lA-3mduA:
21.5		 1a4lA-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.40A 1a4lA-3mduA:
21.5		 1a4lA-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.39A 1a4lB-3mduA:
21.3		 1a4lB-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  56
HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.53A 1a4lC-3mduA:
21.4		 1a4lC-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.34A 1a4lD-3mduA:
21.3		 1a4lD-3mduA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 121
HIS A 206
HIS A 232
HIS A  56
ASP A 320
 NGQ  A 455 (-3.8A)
NGQ  A 455 (-3.9A)
ZN  A 454 (-3.3A)
ZN  A 454 (-3.3A)
ZN  A 454 (-2.9A)
 1.13A 1ituA-3mduA:
11.3		 1ituA-3mduA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_B_CILB452_1
(RENAL DIPEPTIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 121
HIS A 206
HIS A 232
HIS A  56
ASP A 320
 NGQ  A 455 (-3.8A)
NGQ  A 455 (-3.9A)
ZN  A 454 (-3.3A)
ZN  A 454 (-3.3A)
ZN  A 454 (-2.9A)
 1.13A 1ituB-3mduA:
9.4		 1ituB-3mduA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 159
ILE A 177
ARG A 209
GLY A 163
 None
None
NGQ  A 455 (-3.1A)
None
 1.31A 1ve9A-3mduA:
undetectable		 1ve9A-3mduA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  78
TYR A  86
TYR A 121
ARG A 209
 NGQ  A 455 (-4.2A)
None
NGQ  A 455 (-3.8A)
NGQ  A 455 (-3.1A)
 1.47A 1xqlA-3mduA:
4.5
1xqlB-3mduA:
4.4		 1xqlA-3mduA:
23.91
1xqlB-3mduA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 121
ARG A 209
PHE A  78
TYR A  86
 NGQ  A 455 (-3.8A)
NGQ  A 455 (-3.1A)
NGQ  A 455 (-4.2A)
None
 1.46A 1xqlA-3mduA:
4.9
1xqlB-3mduA:
4.4		 1xqlA-3mduA:
23.91
1xqlB-3mduA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 159
ILE A 177
ARG A 209
GLY A 163
 None
None
NGQ  A 455 (-3.1A)
None
 1.29A 2du8G-3mduA:
undetectable		 2du8G-3mduA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 159
ILE A 177
ARG A 209
GLY A 163
 None
None
NGQ  A 455 (-3.1A)
None
 1.31A 2du8J-3mduA:
undetectable		 2du8J-3mduA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 298
HIS A  56
HIS A  58
HIS A 232
 NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
 0.82A 2ow9A-3mduA:
undetectable		 2ow9A-3mduA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.33A 2pgfA-3mduA:
22.4		 2pgfA-3mduA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  56
HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.43A 2pgrA-3mduA:
22.5		 2pgrA-3mduA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.33A 3iaiA-3mduA:
undetectable		 3iaiA-3mduA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.32A 3iaiB-3mduA:
undetectable		 3iaiB-3mduA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.32A 3iaiC-3mduA:
undetectable		 3iaiC-3mduA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 298
HIS A  56
HIS A  58
HIS A 232
 NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
 0.87A 3kecA-3mduA:
undetectable		 3kecA-3mduA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 8 GLU A 235
TYR A  86
GLN A  61
ASP A 320
 NGQ  A 455 (-2.9A)
None
NGQ  A 455 (-3.4A)
ZN  A 454 (-2.9A)
 1.00A 3mjrD-3mduA:
undetectable		 3mjrD-3mduA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A 298
HIS A  56
HIS A  58
HIS A 232
 NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
 0.81A 4a7bA-3mduA:
undetectable		 4a7bA-3mduA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLN A  61
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 NGQ  A 455 (-3.4A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.50A 4aqlA-3mduA:
38.0		 4aqlA-3mduA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLN A  61
LEU A 298
HIS A 232
GLU A 235
HIS A 269
 NGQ  A 455 (-3.4A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.29A 4aqlA-3mduA:
38.0		 4aqlA-3mduA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
HIS A 269
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
None
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.47A 4r88A-3mduA:
29.3		 4r88A-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
HIS A 269
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.03A 4r88A-3mduA:
29.3		 4r88A-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.33A 4r88B-3mduA:
30.1		 4r88B-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.54A 4r88B-3mduA:
30.1		 4r88B-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.01A 4r88B-3mduA:
30.1		 4r88B-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.31A 4r88C-3mduA:
29.6		 4r88C-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.54A 4r88C-3mduA:
29.6		 4r88C-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.00A 4r88C-3mduA:
29.6		 4r88C-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.31A 4r88D-3mduA:
29.6		 4r88D-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.54A 4r88D-3mduA:
29.6		 4r88D-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.01A 4r88D-3mduA:
29.6		 4r88D-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.29A 4r88E-3mduA:
29.2		 4r88E-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.56A 4r88E-3mduA:
29.2		 4r88E-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.05A 4r88E-3mduA:
29.2		 4r88E-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  56
LEU A 298
HIS A 232
GLU A 235
GLU A 295
 ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.32A 4r88F-3mduA:
29.7		 4r88F-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
LEU A 298
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
 0.55A 4r88F-3mduA:
29.7		 4r88F-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 232
GLU A 235
LEU A 298
ASP A 320
SER A 321
 ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-2.9A)
None
 1.02A 4r88F-3mduA:
29.7		 4r88F-3mduA:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.28A 5jn8B-3mduA:
undetectable		 5jn8B-3mduA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 9 GLN A  61
HIS A  58
HIS A  56
LEU A 298
THR A 294
 NGQ  A 455 (-3.4A)
ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-4.7A)
None
 1.40A 5jn8C-3mduA:
undetectable		 5jn8C-3mduA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 10 HIS A  56
HIS A 269
GLU A 235
HIS A 232
THR A 294
 ZN  A 454 (-3.3A)
None
NGQ  A 455 (-2.9A)
ZN  A 454 (-3.3A)
None
 1.29A 5jn8D-3mduA:
undetectable		 5jn8D-3mduA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.30A 6n91A-3mduA:
21.2		 6n91A-3mduA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
LEU A 298
HIS A 232
GLU A 235
HIS A 269
 ZN  A 454 ( 3.2A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.25A 6n91A-3mduA:
21.2		 6n91A-3mduA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
HIS A 232
GLU A 235
HIS A 269
ASP A 320
 ZN  A 454 ( 3.2A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
ZN  A 454 (-2.9A)
 0.30A 6n91B-3mduA:
21.2		 6n91B-3mduA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 3mdu N-FORMIMINO-L-GLUTAM
ATE IMINOHYDROLASE
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  58
LEU A 298
HIS A 232
GLU A 235
HIS A 269
 ZN  A 454 ( 3.2A)
NGQ  A 455 (-4.7A)
ZN  A 454 (-3.3A)
NGQ  A 455 (-2.9A)
None
 1.24A 6n91B-3mduA:
21.2		 6n91B-3mduA:
10.85