SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NGO'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1e6z CHITINASE B
(Serratia
marcescens) 		6 / 9 TYR A  10
PHE A  51
GLY A  96
ASP A 142
ASP A 215
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-3.5A)
 1.01A 1e9lA-1e6zA:
42.3		 1e9lA-1e6zA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 9 TYR A  10
PHE A  51
GLY A  96
ASP A 142
MET A 212
TYR A 214
ASP A 215
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
 0.67A 1e9lA-1e6zA:
42.3		 1e9lA-1e6zA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 11 TYR A  10
PHE A  51
GLY A  96
ASP A 142
MET A 212
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.72A 2a3aA-1e6zA:
12.3		 2a3aA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		10 / 11 TYR A  10
PHE A  51
GLY A  96
TRP A  97
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.58A 2a3aA-1e6zA:
12.3		 2a3aA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		3 / 3 TRP A  97
GLU A 144
TYR A 145
 NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
None
 0.36A 2a3aA-1e6zA:
12.3		 2a3aA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 9 PHE A  51
GLY A  96
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.46A 2a3aB-1e6zA:
9.7		 2a3aB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
ASP A 142
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.81A 2a3bA-1e6zA:
39.4		 2a3bA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
GLU A 144
MET A 212
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.71A 2a3bA-1e6zA:
39.4		 2a3bA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 11 TYR A  10
PHE A  51
GLY A  96
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.44A 2a3bA-1e6zA:
39.4		 2a3bA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 10 PHE A  51
GLY A  96
ASP A 142
GLU A 144
MET A 212
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.90A 2a3bB-1e6zA:
12.7		 2a3bB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 10 PHE A  51
GLY A  96
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.44A 2a3bB-1e6zA:
12.7		 2a3bB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 12 TYR A  10
PHE A  51
GLY A  96
ASP A 142
GLU A 144
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.96A 2a3cA-1e6zA:
12.6		 2a3cA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 12 TYR A  10
PHE A  51
GLY A  96
ASP A 142
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.81A 2a3cA-1e6zA:
12.6		 2a3cA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 12 TYR A  10
PHE A  51
GLY A  96
GLU A 144
MET A 212
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.71A 2a3cA-1e6zA:
12.6		 2a3cA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 12 TYR A  10
PHE A  51
GLY A  96
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.44A 2a3cA-1e6zA:
12.6		 2a3cA-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 12 PHE A  51
GLY A  96
ASP A 142
GLU A 144
MET A 212
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.89A 2a3cB-1e6zA:
12.5		 2a3cB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 12 PHE A  51
GLY A  96
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.42A 2a3cB-1e6zA:
12.5		 2a3cB-1e6zA:
28.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		6 / 12 GLY A 218
ALA A 217
ASP A 215
GLY A 293
THR A 365
PRO A 366
 None
None
NGO  A 502 ( 3.1A)
None
None
None
 1.33A 2nmyA-1e6zA:
undetectable		 2nmyA-1e6zA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 4c7g BETA-N-ACETYLHEXOSAM
INIDASE
(Streptomyces
coelicolor) 		3 / 3 GLN A 361
THR A 354
TRP A 349
 EDO  A1502 (-4.3A)
EDO  A1500 (-3.0A)
NGO  A1495 ( 3.4A)
 1.13A 2rctA-4c7gA:
undetectable		 2rctA-4c7gA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 9 TYR A  10
PHE A  51
GLY A  96
ASP A 142
GLU A 144
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.58A 2uy4A-1e6zA:
18.5		 2uy4A-1e6zA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
ASP A 142
GLU A 144
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.87A 2xtkA-1e6zA:
19.7		 2xtkA-1e6zA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 10 TYR A  10
PHE A  51
GLY A  96
ASP A 142
GLU A 144
TYR A 214
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 (-3.5A)
 0.68A 2xtkB-1e6zA:
19.5		 2xtkB-1e6zA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 7 TRP A  97
GLY A 188
ASP A 215
TRP A 220
ARG A 294
 NAG  A 503 ( 3.7A)
NAG  A 504 ( 4.9A)
NGO  A 502 ( 3.1A)
NAG  A 504 (-3.6A)
NAG  A 503 ( 4.9A)
 0.82A 3arrA-1e6zA:
33.5		 3arrA-1e6zA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 7 GLY A 188
ASP A 215
TRP A 220
ARG A 294
 NAG  A 504 ( 4.9A)
NGO  A 502 ( 3.1A)
NAG  A 504 (-3.6A)
NAG  A 503 ( 4.9A)
 0.64A 3aruA-1e6zA:
33.5		 3aruA-1e6zA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 4c7g BETA-N-ACETYLHEXOSAM
INIDASE
(Streptomyces
coelicolor) 		4 / 5 HIS A 176
ASP A 234
HIS A 238
ASP A 301
 None
None
NGO  A1495 (-4.0A)
NGO  A1495 (-3.8A)
 1.24A 3c0zA-4c7gA:
undetectable		 3c0zA-4c7gA:
22.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
ASP A 142
TYR A 214
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.1A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.78A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		9 / 11 TYR A  10
PHE A  51
GLY A  96
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
TRP A 403
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NGO  A 502 (-3.5A)
 0.40A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		7 / 11 TYR A  10
PHE A  51
GLY A  96
TRP A  97
ASP A 142
TYR A 214
TYR A 292
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.1A)
NGO  A 502 (-4.5A)
NGO  A 502 (-4.8A)
 0.97A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		9 / 11 TYR A  10
PHE A  51
GLY A  96
TRP A  97
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
 NGO  A 502 (-3.2A)
NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
 0.62A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA427_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		5 / 5 TRP A  97
TYR A 145
MET A 212
ASP A 215
TRP A 220
 NAG  A 503 ( 3.7A)
None
NGO  A 502 (-3.4A)
NGO  A 502 ( 3.1A)
NAG  A 504 (-3.6A)
 0.78A 3g6mA-1e6zA:
5.4		 3g6mA-1e6zA:
31.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 4c7g BETA-N-ACETYLHEXOSAM
INIDASE
(Streptomyces
coelicolor) 		11 / 12 ARG A 150
HIS A 176
ASP A 179
ASP A 234
HIS A 238
ASP A 301
TRP A 349
TYR A 381
ASP A 383
TRP A 430
GLU A 432
 NGO  A1495 (-2.8A)
None
None
None
NGO  A1495 (-4.0A)
NGO  A1495 (-3.8A)
NGO  A1495 ( 3.4A)
NGO  A1495 (-4.5A)
NGO  A1495 (-3.0A)
NGO  A1495 (-3.6A)
NGO  A1495 (-2.7A)
 0.36A 3lmyA-4c7gA:
39.3		 3lmyA-4c7gA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 4c7g BETA-N-ACETYLHEXOSAM
INIDASE
(Streptomyces
coelicolor) 		5 / 12 HIS A 174
TRP A 349
TYR A 381
ASP A 383
TRP A 430
 None
NGO  A1495 ( 3.4A)
NGO  A1495 (-4.5A)
NGO  A1495 (-3.0A)
NGO  A1495 (-3.6A)
 1.49A 3lmyA-4c7gA:
39.3		 3lmyA-4c7gA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_B_CP6B563_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 4c7g BETA-N-ACETYLHEXOSAM
INIDASE
(Streptomyces
coelicolor) 		11 / 12 ARG A 150
HIS A 176
ASP A 179
ASP A 234
HIS A 238
ASP A 301
TRP A 332
TRP A 349
TYR A 381
TRP A 430
GLU A 432
 NGO  A1495 (-2.8A)
None
None
None
NGO  A1495 (-4.0A)
NGO  A1495 (-3.8A)
NGO  A1495 (-3.6A)
NGO  A1495 ( 3.4A)
NGO  A1495 (-4.5A)
NGO  A1495 (-3.6A)
NGO  A1495 (-2.7A)
 0.34A 3lmyB-4c7gA:
39.4		 3lmyB-4c7gA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		11 / 11 PHE A  51
GLY A  96
TRP A  97
ASP A 142
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
ARG A 294
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NAG  A 503 ( 4.9A)
NGO  A 502 (-3.5A)
 0.51A 3wqvA-1e6zA:
41.6		 3wqvA-1e6zA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		11 / 11 PHE A  51
GLY A  96
TRP A  97
ASP A 142
GLU A 144
MET A 212
TYR A 214
ASP A 215
TYR A 292
ARG A 294
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.1A)
NGO  A 502 (-3.4A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NGO  A 502 (-4.8A)
NAG  A 503 ( 4.9A)
NGO  A 502 (-3.5A)
 0.53A 3wqwA-1e6zA:
41.6		 3wqwA-1e6zA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 4c7g BETA-N-ACETYLHEXOSAM
INIDASE
(Streptomyces
coelicolor) 		3 / 3 HIS A 176
TRP A 349
SER A 149
 None
NGO  A1495 ( 3.4A)
None
 1.17A 4lrhD-4c7gA:
undetectable		 4lrhD-4c7gA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 4 PHE A  51
ASP A 140
GLY A  96
SER A  93
 NGO  A 502 (-4.7A)
None
NGO  A 502 ( 3.8A)
None
 1.39A 4xp9C-1e6zA:
0.0		 4xp9C-1e6zA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		3 / 3 TRP A  97
GLU A 144
ASP A 215
 NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
NGO  A 502 ( 3.1A)
 0.35A 5gqbA-1e6zA:
34.8		 5gqbA-1e6zA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		8 / 8 PHE A  51
GLY A  96
TRP A  97
GLU A 144
TYR A 214
ASP A 215
ARG A 294
TRP A 403
 NGO  A 502 (-4.7A)
NGO  A 502 ( 3.8A)
NAG  A 503 ( 3.7A)
NGO  A 502 (-3.4A)
NGO  A 502 (-4.5A)
NGO  A 502 ( 3.1A)
NAG  A 503 ( 4.9A)
NGO  A 502 (-3.5A)
 0.42A 5gqbA-1e6zA:
34.8		 5gqbA-1e6zA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1e6z CHITINASE B
(Serratia
marcescens) 		4 / 5 TYR A  10
GLY A   9
GLY A 279
LEU A 211
 NGO  A 502 (-3.2A)
None
None
None
 0.71A 5jlcA-1e6zA:
0.0		 5jlcA-1e6zA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_GLYA607_0
(UNCHARACTERIZED
PROTEIN)		 4c7g BETA-N-ACETYLHEXOSAM
INIDASE
(Streptomyces
coelicolor) 		4 / 4 GLU A 232
ASP A 147
ARG A 150
TRP A 430
 None
None
NGO  A1495 (-2.8A)
NGO  A1495 (-3.6A)
 1.08A 6mn8A-4c7gA:
undetectable		 6mn8A-4c7gA:
21.28