SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NGH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 5 HIS A 191
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 275 (-3.4A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.83A 1os2A-2jsdA:
24.7		 1os2A-2jsdA:
53.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.64A 1os2D-2jsdA:
24.8		 1os2D-2jsdA:
53.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 10 THR A 188
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.8A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.88A 1r55A-2jsdA:
9.1		 1r55A-2jsdA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_A_ADNA1501_1
(CLASS B ACID
PHOSPHATASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 10 PHE A 218
TYR A 248
GLY A 184
ARG A 186
THR A 212
 None
NGH  A 277 (-4.4A)
CA  A 273 (-4.5A)
None
None
 1.47A 1rmtA-2jsdA:
undetectable		 1rmtA-2jsdA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_A_ADNA1501_1
(CLASS B ACID
PHOSPHATASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 10 TYR A 248
LEU A 189
GLY A 184
ARG A 186
THR A 212
 NGH  A 277 (-4.4A)
NGH  A 277 (-4.1A)
CA  A 273 (-4.5A)
None
None
 1.36A 1rmtA-2jsdA:
undetectable		 1rmtA-2jsdA:
23.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.62A 1uttA-2jsdA:
25.4		 1uttA-2jsdA:
54.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.60A 1utzA-2jsdA:
25.1		 1utzA-2jsdA:
54.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.60A 1utzB-2jsdA:
25.4		 1utzB-2jsdA:
54.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 6 HIS A 191
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 275 (-3.4A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.78A 1y93A-2jsdA:
25.0		 1y93A-2jsdA:
54.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B8J_B_ADNB331_1
(CLASS B ACID
PHOSPHATASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 10 PHE A 218
TYR A 248
GLY A 184
ARG A 186
THR A 212
 None
NGH  A 277 (-4.4A)
CA  A 273 (-4.5A)
None
None
 1.43A 2b8jB-2jsdA:
undetectable		 2b8jB-2jsdA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B8J_B_ADNB331_1
(CLASS B ACID
PHOSPHATASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 10 TYR A 248
LEU A 189
GLY A 184
ARG A 186
THR A 212
 NGH  A 277 (-4.4A)
NGH  A 277 (-4.1A)
CA  A 273 (-4.5A)
None
None
 1.25A 2b8jB-2jsdA:
undetectable		 2b8jB-2jsdA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.72A 2einA-2jsdA:
undetectable		 2einA-2jsdA:
15.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.65A 2hu6A-2jsdA:
25.2		 2hu6A-2jsdA:
54.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 9 LEU A 189
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 (-4.1A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.70A 2jihA-2jsdA:
9.9		 2jihA-2jsdA:
18.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 6 HIS A 191
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 275 (-3.4A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.66A 2ow9A-2jsdA:
24.8		 2ow9A-2jsdA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.59A 2ow9B-2jsdA:
24.4		 2ow9B-2jsdA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.54A 2ozrC-2jsdA:
24.9		 2ozrC-2jsdA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.61A 2ozrD-2jsdA:
25.0		 2ozrD-2jsdA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.69A 2ozrE-2jsdA:
24.3		 2ozrE-2jsdA:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 226
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.40A 2ozrF-2jsdA:
24.5		 2ozrF-2jsdA:
57.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.75A 2y69A-2jsdA:
undetectable		 2y69A-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.77A 2zxwA-2jsdA:
undetectable		 2zxwA-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.76A 3ablA-2jsdA:
undetectable		 3ablA-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.79A 3ablN-2jsdA:
undetectable		 3ablN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.76A 3asnN-2jsdA:
undetectable		 3asnN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.64A 3bvdA-2jsdA:
undetectable		 3bvdA-2jsdA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.76A 3dtuA-2jsdA:
undetectable		 3dtuA-2jsdA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 9 LEU A 189
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 (-4.1A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.67A 3hy7A-2jsdA:
10.5		 3hy7A-2jsdA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 9 LEU A 189
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 (-4.1A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.64A 3hy7B-2jsdA:
10.4		 3hy7B-2jsdA:
21.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 5 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.58A 3kecA-2jsdA:
25.0		 3kecA-2jsdA:
58.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 5 HIS A 191
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 275 (-3.4A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.70A 3likA-2jsdA:
25.1		 3likA-2jsdA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.61A 3lilA-2jsdA:
25.2		 3lilA-2jsdA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 5 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.64A 3ljgA-2jsdA:
25.3		 3ljgA-2jsdA:
54.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 5 HIS A 191
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 275 (-3.4A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.74A 3lkaA-2jsdA:
25.2		 3lkaA-2jsdA:
54.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.73A 3s33A-2jsdA:
undetectable		 3s33A-2jsdA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.68A 3s38A-2jsdA:
undetectable		 3s38A-2jsdA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.74A 3s39A-2jsdA:
undetectable		 3s39A-2jsdA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.73A 3s3aA-2jsdA:
undetectable		 3s3aA-2jsdA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.77A 3s3bA-2jsdA:
undetectable		 3s3bA-2jsdA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.75A 3s3cA-2jsdA:
undetectable		 3s3cA-2jsdA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.72A 3s3dA-2jsdA:
undetectable		 3s3dA-2jsdA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.72A 3wg7A-2jsdA:
undetectable		 3wg7A-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.74A 3wg7N-2jsdA:
undetectable		 3wg7N-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.73A 3x2qN-2jsdA:
undetectable		 3x2qN-2jsdA:
15.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		5 / 6 HIS A 191
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 275 (-3.4A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.66A 4a7bA-2jsdA:
25.0		 4a7bA-2jsdA:
58.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 5 HIS A 191
HIS A 226
GLU A 227
HIS A 230
 ZN  A 275 (-3.4A)
NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
 0.79A 4a7bB-2jsdA:
24.4		 4a7bB-2jsdA:
58.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.75A 5b1aA-2jsdA:
undetectable		 5b1aA-2jsdA:
15.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.63A 5n5jA-2jsdA:
25.2		 5n5jA-2jsdA:
54.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		4 / 5 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 NGH  A 277 ( 3.0A)
NGH  A 277 (-3.6A)
ZN  A 276 ( 3.3A)
ZN  A 276 ( 3.0A)
 0.62A 5n5kA-2jsdA:
24.9		 5n5kA-2jsdA:
53.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.72A 5x19N-2jsdA:
undetectable		 5x19N-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.68A 5x1bA-2jsdA:
undetectable		 5x1bA-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.68A 5x1bN-2jsdA:
undetectable		 5x1bN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.68A 5x1fN-2jsdA:
undetectable		 5x1fN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.74A 5xdqA-2jsdA:
undetectable		 5xdqA-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.75A 5xdqN-2jsdA:
undetectable		 5xdqN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.74A 5xdxA-2jsdA:
undetectable		 5xdxA-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.74A 5xdxN-2jsdA:
undetectable		 5xdxN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.76A 5z84N-2jsdA:
undetectable		 5z84N-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.79A 5z85A-2jsdA:
undetectable		 5z85A-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.74A 5z85N-2jsdA:
undetectable		 5z85N-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.75A 5z86A-2jsdA:
undetectable		 5z86A-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.77A 5z86N-2jsdA:
undetectable		 5z86N-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.73A 5zcoN-2jsdA:
undetectable		 5zcoN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.76A 5zcpA-2jsdA:
undetectable		 5zcpA-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.77A 5zcpN-2jsdA:
undetectable		 5zcpN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.76A 5zcqA-2jsdA:
undetectable		 5zcqA-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.76A 5zcqN-2jsdA:
undetectable		 5zcqN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.73A 6hu9a-2jsdA:
undetectable		 6hu9a-2jsdA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.73A 6hu9m-2jsdA:
undetectable		 6hu9m-2jsdA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.75A 6nknA-2jsdA:
undetectable		 6nknA-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.75A 6nknN-2jsdA:
undetectable		 6nknN-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.71A 6nmfA-2jsdA:
undetectable		 6nmfA-2jsdA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jsd MATRIX
METALLOPROTEINASE-20
(Homo
sapiens) 		3 / 3 HIS A 236
HIS A 230
HIS A 226
 ZN  A 276 ( 3.0A)
ZN  A 276 ( 3.3A)
NGH  A 277 ( 3.0A)
 0.75A 6nmpA-2jsdA:
undetectable		 6nmpA-2jsdA:
15.51