SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NG1'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 8 TYR A  24
PHE A  22
GLY A  25
THR A 516
 None
None
None
NG1  A 901 (-3.0A)
 0.98A 1ykiA-2dkdA:
undetectable
1ykiB-2dkdA:
undetectable		 1ykiA-2dkdA:
19.12
1ykiB-2dkdA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		3 / 3 ARG A 512
GLU A 484
SER A 351
 NG1  A 901 (-3.0A)
None
None
 0.84A 2xctD-2dkdA:
undetectable		 2xctD-2dkdA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		3 / 3 TYR A 346
GLU A 484
THR A  26
 NG1  A 901 ( 3.6A)
None
NG1  A 901 (-4.8A)
 1.03A 2y7hB-2dkdA:
undetectable		 2y7hB-2dkdA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		3 / 3 PRO A 490
LEU A 487
ARG A 512
 None
None
NG1  A 901 (-3.0A)
 0.88A 3aqiA-2dkdA:
undetectable		 3aqiA-2dkdA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2dkd PHOSPHOACETYLGLUCOSA
MINE MUTASE
(Candida
albicans) 		4 / 5 SER A  66
ARG A 295
GLY A 369
GLU A 484
 ZN  A 921 ( 2.3A)
PO4  A 911 ( 4.1A)
NG1  A 901 ( 3.7A)
None
 1.30A 3k9fA-2dkdA:
2.4
3k9fB-2dkdA:
2.4
3k9fC-2dkdA:
undetectable		 3k9fA-2dkdA:
22.28
3k9fB-2dkdA:
22.28
3k9fC-2dkdA:
17.73