SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NDZ'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4S_A_TPVA201_1 (PROTEIN (HIV-1 PROTEASE))	3qxm	GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2 (Homo sapiens)	5 / 10	ALA A 640 ASP A 641 ASP A 642 GLY A 726 PHE A 704	None None None None NDZ A 301 ( 4.9A)	1.25A	1d4sA-3qxmA: undetectable	1d4sA-3qxmA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E9R_A_ACTA700_0 (PURINE-NUCLEOSIDE PHOSPHORYLASE)	3qxm	GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2 (Homo sapiens)	4 / 6	GLY A 458 GLY A 657 MET A 660 ASN A 468	None NDZ A 301 (-3.4A) None None	1.01A	3e9rA-3qxmA: undetectable	3e9rA-3qxmA: 22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E9R_C_ACTC700_0 (PURINE-NUCLEOSIDE PHOSPHORYLASE)	3qxm	GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 2 (Homo sapiens)	4 / 6	GLY A 458 GLY A 657 MET A 660 ASN A 468	None NDZ A 301 (-3.4A) None None	1.00A	3e9rC-3qxmA: undetectable	3e9rC-3qxmA: 22.84