SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NDB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5u77 OXYSTEROL-BINDING
PROTEIN-RELATED
PROTEIN 8
(Homo
sapiens) 		4 / 7 VAL A  51
GLY A  49
THR A  95
ILE A  38
 None
NDB  A 201 ( 4.6A)
None
None
 0.85A 1gtnC-5u77A:
undetectable
1gtnD-5u77A:
undetectable		 1gtnC-5u77A:
19.67
1gtnD-5u77A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 5u77 OXYSTEROL-BINDING
PROTEIN-RELATED
PROTEIN 8
(Homo
sapiens) 		4 / 6 LEU A 103
LEU A  98
ILE A 105
ARG A  18
 None
NDB  A 201 (-4.3A)
None
None
 0.94A 2rlfC-5u77A:
undetectable
2rlfD-5u77A:
undetectable		 2rlfC-5u77A:
16.26
2rlfD-5u77A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5u77 OXYSTEROL-BINDING
PROTEIN-RELATED
PROTEIN 8
(Homo
sapiens) 		5 / 12 LEU A  72
LEU A 103
LEU A  98
GLN A  96
CYH A  69
 None
None
NDB  A 201 (-4.3A)
None
None
 1.31A 3d90A-5u77A:
undetectable		 3d90A-5u77A:
18.18