SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NBD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Leishmania
mexicana) 		4 / 7 ASN A 335
TYR A 339
ASN A 169
TYR A 333
 NBD  A 361 (-3.9A)
NBD  A 361 (-3.6A)
None
None
 0.88A 1dssG-1gyqA:
49.0		 1dssG-1gyqA:
54.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Leishmania
mexicana) 		7 / 7 SER A 165
THR A 167
ASN A 169
CYH A 170
TYR A 333
ASN A 335
TYR A 339
 None
None
None
None
None
NBD  A 361 (-3.9A)
NBD  A 361 (-3.6A)
 0.19A 1dssG-1gyqA:
49.0		 1dssG-1gyqA:
54.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Leishmania
mexicana) 		4 / 8 ASN A 335
TYR A 339
ASN A 169
TYR A 333
 NBD  A 361 (-3.9A)
NBD  A 361 (-3.6A)
None
None
 0.88A 1dssR-1gyqA:
49.2		 1dssR-1gyqA:
54.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Leishmania
mexicana) 		8 / 8 SER A 165
THR A 167
ASN A 169
CYH A 170
HIS A 194
TYR A 333
ASN A 335
TYR A 339
 None
None
None
None
None
None
NBD  A 361 (-3.9A)
NBD  A 361 (-3.6A)
 0.29A 1dssR-1gyqA:
49.2		 1dssR-1gyqA:
54.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Leishmania
mexicana) 		5 / 12 LEU A  97
GLY A 122
LEU A 113
GLY A 112
LYS A  89
 None
None
NBD  A 361 (-4.7A)
NBD  A 361 (-3.6A)
None
 1.17A 1y4lA-1gyqA:
undetectable		 1y4lA-1gyqA:
16.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Leishmania
mexicana) 		4 / 8 ASN A 335
TYR A 339
ASN A 169
TYR A 333
 NBD  A 361 (-3.9A)
NBD  A 361 (-3.6A)
None
None
 0.91A 3dmtC-1gyqA:
55.9		 3dmtC-1gyqA:
84.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)
(Leishmania
mexicana) 		8 / 8 SER A 165
THR A 167
ASN A 169
CYH A 170
HIS A 194
TYR A 333
ASN A 335
TYR A 339
 None
None
None
None
None
None
NBD  A 361 (-3.9A)
NBD  A 361 (-3.6A)
 0.27A 3dmtC-1gyqA:
55.9		 3dmtC-1gyqA:
84.12