SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NAK'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 4iyo CYSTATHIONINE
GAMMA-LYASE-LIKE
PROTEIN, LYS201A
MODIFIED
(Xanthomonas
oryzae) 		4 / 6 ASP B 109
GLY B 367
PRO B 350
THR B 354
 None
None
None
NAK  B 402 (-3.6A)
 1.04A 4l1aB-4iyoB:
undetectable		 4l1aB-4iyoB:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 4iyo CYSTATHIONINE
GAMMA-LYASE-LIKE
PROTEIN, LYS201A
MODIFIED
(Xanthomonas
oryzae) 		4 / 5 ASN B 213
SER B 207
LEU B 340
ASN B 160
 None
LLP  B 210 ( 2.6A)
LLP  B 210 (-4.3A)
NAK  B 402 (-3.3A)
 1.12A 4n09C-4iyoB:
undetectable		 4n09C-4iyoB:
22.93