SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'NAA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1433_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		7 / 11 PHE A  58
GLY A  98
ASP A 138
MET A 210
TYR A 212
TYR A 267
TRP A 358
 AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 (-3.1A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.91A 2a3aA-1hkkA:
14.0		 2a3aA-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1433_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		9 / 11 TYR A  27
PHE A  58
GLY A  98
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 358
 AMI  A1388 (-3.6A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.73A 2a3aA-1hkkA:
14.0		 2a3aA-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1433_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		8 / 11 TYR A  27
PHE A  58
GLY A  98
TRP A  99
GLU A 140
MET A 210
TYR A 212
TRP A 358
 AMI  A1388 (-3.6A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
NAA  A1390 ( 4.3A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 (-3.5A)
 0.81A 2a3aA-1hkkA:
14.0		 2a3aA-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1435_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		3 / 3 TRP A  99
GLU A 140
TYR A 141
 NAA  A1390 ( 4.3A)
AMI  A1388 ( 3.3A)
NAA  A1390 (-4.5A)
 0.48A 2a3aA-1hkkA:
14.0		 2a3aA-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_B_TEPB2433_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		8 / 9 PHE A  58
GLY A  98
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 358
 AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.56A 2a3aB-1hkkA:
43.9		 2a3aB-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		8 / 11 TYR A  27
PHE A  58
GLY A  98
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 358
 AMI  A1388 (-3.6A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.74A 2a3bA-1hkkA:
43.8		 2a3bA-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_B_CFFB2435_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		6 / 10 PHE A  58
ASP A 138
MET A 210
TYR A 212
TYR A 267
TRP A 358
 AMI  A1388 (-4.8A)
AMI  A1388 (-3.1A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.97A 2a3bB-1hkkA:
14.0		 2a3bB-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_B_CFFB2435_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		7 / 10 PHE A  58
GLY A  98
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 358
 AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.48A 2a3bB-1hkkA:
14.0		 2a3bB-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		7 / 12 TRP A  31
PHE A  58
ASP A 138
GLU A 140
MET A 210
TYR A 212
TRP A 358
 NAA  A1386 (-4.0A)
AMI  A1388 (-4.8A)
AMI  A1388 (-3.1A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 (-3.5A)
 1.17A 2a3cA-1hkkA:
13.9		 2a3cA-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		8 / 12 TYR A  27
TRP A  31
PHE A  58
GLY A  98
GLU A 140
MET A 210
TYR A 212
TRP A 358
 AMI  A1388 (-3.6A)
NAA  A1386 (-4.0A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 (-3.5A)
 0.98A 2a3cA-1hkkA:
13.9		 2a3cA-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		9 / 12 TYR A  27
TRP A  31
PHE A  58
GLY A  98
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 358
 AMI  A1388 (-3.6A)
NAA  A1386 (-4.0A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.73A 2a3cA-1hkkA:
13.9		 2a3cA-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		7 / 12 TRP A  31
PHE A  58
ASP A 138
GLU A 140
MET A 210
TYR A 212
TRP A 358
 NAA  A1386 (-4.0A)
AMI  A1388 (-4.8A)
AMI  A1388 (-3.1A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 (-3.5A)
 1.12A 2a3cB-1hkkA:
43.9		 2a3cB-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		7 / 12 TRP A  31
PHE A  58
ASP A 138
MET A 210
TYR A 212
TYR A 267
TRP A 358
 NAA  A1386 (-4.0A)
AMI  A1388 (-4.8A)
AMI  A1388 (-3.1A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.96A 2a3cB-1hkkA:
43.9		 2a3cB-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		7 / 12 TRP A  31
PHE A  58
GLY A  98
GLU A 140
MET A 210
TYR A 212
TRP A 358
 NAA  A1386 (-4.0A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 (-3.5A)
 0.81A 2a3cB-1hkkA:
43.9		 2a3cB-1hkkA:
30.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		8 / 12 TRP A  31
PHE A  58
GLY A  98
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 358
 NAA  A1386 (-4.0A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.51A 2a3cB-1hkkA:
43.9		 2a3cB-1hkkA:
30.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		4 / 6 TRP A  99
ASP A 213
TRP A 218
ARG A 269
 NAA  A1390 ( 4.3A)
AMI  A1388 ( 2.9A)
NAA  A1390 (-3.2A)
NAA  A1389 (-3.2A)
 0.42A 3arqA-1hkkA:
41.3		 3arqA-1hkkA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		5 / 7 TRP A  99
GLY A 187
ASP A 213
TRP A 218
ARG A 269
 NAA  A1390 ( 4.3A)
AMI  A1391 (-3.3A)
AMI  A1388 ( 2.9A)
NAA  A1390 (-3.2A)
NAA  A1389 (-3.2A)
 0.60A 3arrA-1hkkA:
42.2		 3arrA-1hkkA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		4 / 7 GLY A 187
ASP A 213
TRP A 218
ARG A 269
 AMI  A1391 (-3.3A)
AMI  A1388 ( 2.9A)
NAA  A1390 (-3.2A)
NAA  A1389 (-3.2A)
 0.34A 3aruA-1hkkA:
42.1		 3aruA-1hkkA:
25.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		9 / 11 PHE A  58
GLY A  98
TRP A  99
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 358
 AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
NAA  A1390 ( 4.3A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.72A 3g6mA-1hkkA:
44.6		 3g6mA-1hkkA:
33.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		9 / 11 TYR A  27
PHE A  58
GLY A  98
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
TRP A 358
 AMI  A1388 (-3.6A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
AMI  A1388 (-3.5A)
 0.79A 3g6mA-1hkkA:
44.6		 3g6mA-1hkkA:
33.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA427_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		5 / 5 TRP A  99
TYR A 141
MET A 210
ASP A 213
TRP A 218
 NAA  A1390 ( 4.3A)
NAA  A1390 (-4.5A)
AMI  A1388 (-3.3A)
AMI  A1388 ( 2.9A)
NAA  A1390 (-3.2A)
 0.84A 3g6mA-1hkkA:
44.6		 3g6mA-1hkkA:
33.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQV_A_GCSA501_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		11 / 11 PHE A  58
GLY A  98
TRP A  99
ASP A 138
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
ARG A 269
TRP A 358
 AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
NAA  A1390 ( 4.3A)
AMI  A1388 (-3.1A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
NAA  A1389 (-3.2A)
AMI  A1388 (-3.5A)
 0.47A 3wqvA-1hkkA:
55.2		 3wqvA-1hkkA:
39.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQW_A_GCSA501_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		11 / 11 PHE A  58
GLY A  98
TRP A  99
ASP A 138
GLU A 140
MET A 210
TYR A 212
ASP A 213
TYR A 267
ARG A 269
TRP A 358
 AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
NAA  A1390 ( 4.3A)
AMI  A1388 (-3.1A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1387 (-3.6A)
NAA  A1389 (-3.2A)
AMI  A1388 (-3.5A)
 0.50A 3wqwA-1hkkA:
55.2		 3wqwA-1hkkA:
39.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		4 / 8 ASP A 213
ASP A 138
ASP A 136
ASN A 100
 AMI  A1388 ( 2.9A)
AMI  A1388 (-3.1A)
AMI  A1388 ( 4.9A)
NAA  A1387 (-3.9A)
 1.07A 4feuD-1hkkA:
0.0		 4feuD-1hkkA:
21.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		5 / 7 THR A  29
TRP A  31
ARG A  35
TRP A 358
LEU A 362
 None
NAA  A1386 (-4.0A)
None
AMI  A1388 (-3.5A)
None
 0.45A 4nsbA-1hkkA:
55.4		 4nsbA-1hkkA:
50.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		3 / 3 TRP A  99
GLU A 140
ASP A 213
 NAA  A1390 ( 4.3A)
AMI  A1388 ( 3.3A)
AMI  A1388 ( 2.9A)
 0.35A 5gqbA-1hkkA:
44.5		 5gqbA-1hkkA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 1hkk CHITOTRIOSIDASE-1
(Homo
sapiens) 		8 / 8 PHE A  58
GLY A  98
TRP A  99
GLU A 140
TYR A 212
ASP A 213
ARG A 269
TRP A 358
 AMI  A1388 (-4.8A)
AMI  A1388 ( 3.7A)
NAA  A1390 ( 4.3A)
AMI  A1388 ( 3.3A)
AMI  A1388 (-4.8A)
AMI  A1388 ( 2.9A)
NAA  A1389 (-3.2A)
AMI  A1388 (-3.5A)
 0.53A 5gqbA-1hkkA:
44.5		 5gqbA-1hkkA:
22.05