SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'N73'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 5 HIS A 190
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 303 ( 3.2A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.17A 1os2A-4xctA:
28.6		 1os2A-4xctA:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.13A 1os2D-4xctA:
28.7		 1os2D-4xctA:
49.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.13A 1uttA-4xctA:
29.1		 1uttA-4xctA:
50.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.11A 1utzA-4xctA:
29.3		 1utzA-4xctA:
50.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.10A 1utzB-4xctA:
29.5		 1utzB-4xctA:
50.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 6 HIS A 190
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 303 ( 3.2A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.16A 1y93A-4xctA:
29.1		 1y93A-4xctA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.08A 2hu6A-4xctA:
29.4		 2hu6A-4xctA:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 9 HIS A 226
GLU A 227
HIS A 230
HIS A 236
MET A 247
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
None
 0.52A 2jihA-4xctA:
11.0		 2jihA-4xctA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 9 LEU A 188
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 N73  A 301 (-4.4A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.43A 2jihA-4xctA:
11.0		 2jihA-4xctA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 8 LEU A 188
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 N73  A 301 (-4.4A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.35A 2jihB-4xctA:
11.3		 2jihB-4xctA:
19.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 6 HIS A 190
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 303 ( 3.2A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.32A 2ow9A-4xctA:
28.0		 2ow9A-4xctA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 6 LEU A 187
HIS A 190
HIS A 226
HIS A 230
HIS A 236
 N73  A 301 (-4.0A)
ZN  A 303 ( 3.2A)
ZN  A 302 ( 3.2A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.75A 2ow9A-4xctA:
28.0		 2ow9A-4xctA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.13A 2ow9B-4xctA:
28.2		 2ow9B-4xctA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.18A 2ozrC-4xctA:
28.0		 2ozrC-4xctA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.24A 2ozrD-4xctA:
28.2		 2ozrD-4xctA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.29A 2ozrE-4xctA:
28.4		 2ozrE-4xctA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		3 / 3 HIS A 190
GLU A 227
HIS A 230
 ZN  A 303 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
 0.48A 3ba0A-4xctA:
26.1		 3ba0A-4xctA:
50.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 9 LEU A 188
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 N73  A 301 (-4.4A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.47A 3hy7A-4xctA:
11.4		 3hy7A-4xctA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 9 LEU A 188
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 N73  A 301 (-4.4A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.38A 3hy7B-4xctA:
11.3		 3hy7B-4xctA:
23.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 5 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.15A 3kecA-4xctA:
27.9		 3kecA-4xctA:
57.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 5 LEU A 187
HIS A 226
HIS A 230
HIS A 236
 N73  A 301 (-4.0A)
ZN  A 302 ( 3.2A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.74A 3kecA-4xctA:
27.9		 3kecA-4xctA:
57.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		3 / 3 HIS A 226
GLU A 227
HIS A 230
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
 0.11A 3kecB-4xctA:
28.1		 3kecB-4xctA:
57.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 5 HIS A 190
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 303 ( 3.2A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.29A 3likA-4xctA:
29.4		 3likA-4xctA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.09A 3lilA-4xctA:
29.5		 3lilA-4xctA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 5 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.14A 3ljgA-4xctA:
29.3		 3ljgA-4xctA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 5 HIS A 190
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 303 ( 3.2A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.27A 3lkaA-4xctA:
29.2		 3lkaA-4xctA:
50.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 6 HIS A 190
HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 303 ( 3.2A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.35A 4a7bA-4xctA:
28.2		 4a7bA-4xctA:
57.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 6 LEU A 187
HIS A 190
HIS A 226
HIS A 230
HIS A 236
 N73  A 301 (-4.0A)
ZN  A 303 ( 3.2A)
ZN  A 302 ( 3.2A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.78A 4a7bA-4xctA:
28.2		 4a7bA-4xctA:
57.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		5 / 5 LEU A 187
HIS A 190
HIS A 226
GLU A 227
HIS A 230
 N73  A 301 (-4.0A)
ZN  A 303 ( 3.2A)
ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
 0.67A 4a7bB-4xctA:
28.3		 4a7bB-4xctA:
57.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 4 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.09A 5n5jA-4xctA:
29.5		 5n5jA-4xctA:
50.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 4xct MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9
(Homo
sapiens) 		4 / 5 HIS A 226
GLU A 227
HIS A 230
HIS A 236
 ZN  A 302 ( 3.2A)
N73  A 301 (-2.5A)
ZN  A 302 ( 3.3A)
ZN  A 302 ( 3.3A)
 0.10A 5n5kA-4xctA:
29.3		 5n5kA-4xctA:
50.31