SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'N4P'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5xnc -
(-) 		5 / 11 TYR A 290
PHE A 287
SER A 260
VAL A 237
PHE A 253
 N4P  A 402 (-4.7A)
None
None
None
None
 1.46A 1q23G-5xncA:
undetectable		 1q23G-5xncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQA_C_DX4C270_0
(PTERIDINE REDUCTASE
1)		 5xnc -
(-) 		4 / 6 SER A 318
ASP A 160
TYR A 290
PRO A 227
 N4P  A 402 ( 4.0A)
N4P  A 402 (-2.7A)
N4P  A 402 (-4.7A)
MTA  A 401 (-3.7A)
 1.43A 3jqaC-5xncA:
5.0		 3jqaC-5xncA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5xnc -
(-) 		3 / 3 TYR A 295
ASP A 126
ASP A 344
 None
N4P  A 402 ( 3.6A)
None
 0.88A 4a6eA-5xncA:
8.8		 4a6eA-5xncA:
undetectable