SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MYR'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 1c9sA-3ee4A:
undetectable
1c9sK-3ee4A:
undetectable		 1c9sA-3ee4A:
12.95
1c9sK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 1c9sA-3ee4A:
undetectable
1c9sB-3ee4A:
undetectable		 1c9sA-3ee4A:
12.95
1c9sB-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.39A 1c9sB-3ee4A:
undetectable
1c9sC-3ee4A:
undetectable		 1c9sB-3ee4A:
12.95
1c9sC-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 1c9sC-3ee4A:
undetectable
1c9sD-3ee4A:
undetectable		 1c9sC-3ee4A:
12.95
1c9sD-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 1c9sD-3ee4A:
undetectable
1c9sE-3ee4A:
undetectable		 1c9sD-3ee4A:
12.95
1c9sE-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 1c9sE-3ee4A:
undetectable
1c9sF-3ee4A:
undetectable		 1c9sE-3ee4A:
12.95
1c9sF-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 1c9sF-3ee4A:
undetectable
1c9sG-3ee4A:
undetectable		 1c9sF-3ee4A:
12.95
1c9sG-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 1c9sG-3ee4A:
undetectable
1c9sH-3ee4A:
undetectable		 1c9sG-3ee4A:
12.95
1c9sH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 1c9sH-3ee4A:
undetectable
1c9sI-3ee4A:
undetectable		 1c9sH-3ee4A:
12.95
1c9sI-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 1c9sJ-3ee4A:
undetectable
1c9sK-3ee4A:
undetectable		 1c9sJ-3ee4A:
12.95
1c9sK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 1c9sL-3ee4A:
undetectable
1c9sM-3ee4A:
undetectable		 1c9sL-3ee4A:
12.95
1c9sM-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 1c9sM-3ee4A:
undetectable
1c9sN-3ee4A:
undetectable		 1c9sM-3ee4A:
12.95
1c9sN-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 1c9sO-3ee4A:
undetectable
1c9sP-3ee4A:
undetectable		 1c9sO-3ee4A:
12.95
1c9sP-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 1c9sS-3ee4A:
undetectable
1c9sT-3ee4A:
undetectable		 1c9sS-3ee4A:
12.95
1c9sT-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 5zvt N-TERMINUS OF OUTER
CAPSID PROTEIN VP5
C-TERMINUS OF OUTER
CAPSID PROTEIN VP5
(Aquareovirus
C;
Aquareovirus
C) 		5 / 11 LEU B 163
LEU B 187
MET B 167
LEU B 218
ILE A  13
 None
MYR  A 101 (-4.2A)
MYR  A 101 (-3.6A)
None
MYR  A 101 (-4.7A)
 1.36A 1ee2A-5zvtB:
undetectable		 1ee2A-5zvtB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 5zvt N-TERMINUS OF OUTER
CAPSID PROTEIN VP5
C-TERMINUS OF OUTER
CAPSID PROTEIN VP5
(Aquareovirus
C;
Aquareovirus
C) 		5 / 11 LEU B 163
LEU B 187
MET B 167
LEU B 218
ILE A  13
 None
MYR  A 101 (-4.2A)
MYR  A 101 (-3.6A)
None
MYR  A 101 (-4.7A)
 1.41A 1ee2B-5zvtB:
undetectable		 1ee2B-5zvtB:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 1uva NONSPECIFIC LIPID
TRANSFER PROTEIN 1
(Oryza
sativa) 		5 / 12 ALA A  38
ARG A  44
ALA A  47
LEU A  51
TYR A  79
 MYR  A 100 ( 4.4A)
MYR  A 100 (-4.4A)
None
MYR  A 100 ( 4.6A)
None
 0.70A 1fk6A-1uvaA:
17.4		 1fk6A-1uvaA:
78.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 1uva NONSPECIFIC LIPID
TRANSFER PROTEIN 1
(Oryza
sativa) 		6 / 12 VAL A  31
ALA A  38
ARG A  44
ALA A  47
LEU A  51
ALA A  55
 MYR  A 100 ( 4.1A)
MYR  A 100 ( 4.4A)
MYR  A 100 (-4.4A)
None
MYR  A 100 ( 4.6A)
None
 0.54A 1fk6A-1uvaA:
17.4		 1fk6A-1uvaA:
78.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 1uva NONSPECIFIC LIPID
TRANSFER PROTEIN 1
(Oryza
sativa) 		6 / 12 VAL A  31
ALA A  38
ARG A  44
ALA A  47
LEU A  51
ILE A  69
 MYR  A 100 ( 4.1A)
MYR  A 100 ( 4.4A)
MYR  A 100 (-4.4A)
None
MYR  A 100 ( 4.6A)
MYR  A 100 (-4.2A)
 0.53A 1fk6A-1uvaA:
17.4		 1fk6A-1uvaA:
78.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 1uva NONSPECIFIC LIPID
TRANSFER PROTEIN 1
(Oryza
sativa) 		6 / 12 VAL A  31
LEU A  34
ALA A  38
ALA A  47
LEU A  51
ALA A  55
 MYR  A 100 ( 4.1A)
MYR  A 100 ( 4.0A)
MYR  A 100 ( 4.4A)
None
MYR  A 100 ( 4.6A)
None
 0.60A 1fk6A-1uvaA:
17.4		 1fk6A-1uvaA:
78.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 1uva NONSPECIFIC LIPID
TRANSFER PROTEIN 1
(Oryza
sativa) 		6 / 12 VAL A  31
LEU A  34
ALA A  38
ALA A  47
LEU A  51
ILE A  69
 MYR  A 100 ( 4.1A)
MYR  A 100 ( 4.0A)
MYR  A 100 ( 4.4A)
None
MYR  A 100 ( 4.6A)
MYR  A 100 (-4.2A)
 0.55A 1fk6A-1uvaA:
17.4		 1fk6A-1uvaA:
78.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 1gtfA-3ee4A:
undetectable
1gtfK-3ee4A:
undetectable		 1gtfA-3ee4A:
12.95
1gtfK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.39A 1gtfA-3ee4A:
undetectable
1gtfB-3ee4A:
undetectable		 1gtfA-3ee4A:
12.95
1gtfB-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 1gtfB-3ee4A:
undetectable
1gtfC-3ee4A:
undetectable		 1gtfB-3ee4A:
12.95
1gtfC-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.40A 1gtfC-3ee4A:
undetectable
1gtfD-3ee4A:
undetectable		 1gtfC-3ee4A:
12.95
1gtfD-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.39A 1gtfE-3ee4A:
undetectable
1gtfF-3ee4A:
undetectable		 1gtfE-3ee4A:
12.95
1gtfF-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 1gtfF-3ee4A:
undetectable
1gtfG-3ee4A:
undetectable		 1gtfF-3ee4A:
12.95
1gtfG-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 1gtfG-3ee4A:
undetectable
1gtfH-3ee4A:
undetectable		 1gtfG-3ee4A:
12.95
1gtfH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 1gtfH-3ee4A:
undetectable
1gtfI-3ee4A:
undetectable		 1gtfH-3ee4A:
12.95
1gtfI-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.39A 1gtfI-3ee4A:
undetectable
1gtfJ-3ee4A:
undetectable		 1gtfI-3ee4A:
12.95
1gtfJ-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 1gtfO-3ee4A:
undetectable
1gtfP-3ee4A:
undetectable		 1gtfO-3ee4A:
12.95
1gtfP-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 1gtfP-3ee4A:
undetectable
1gtfQ-3ee4A:
undetectable		 1gtfP-3ee4A:
12.95
1gtfQ-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 1gtfT-3ee4A:
undetectable
1gtfU-3ee4A:
undetectable		 1gtfT-3ee4A:
12.95
1gtfU-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 1gtfU-3ee4A:
undetectable
1gtfV-3ee4A:
undetectable		 1gtfU-3ee4A:
12.95
1gtfV-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.39A 1gtfL-3ee4A:
undetectable
1gtfV-3ee4A:
undetectable		 1gtfL-3ee4A:
12.95
1gtfV-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 8 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.41A 1gtnA-3ee4A:
undetectable
1gtnB-3ee4A:
undetectable		 1gtnA-3ee4A:
12.95
1gtnB-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 1gtnG-3ee4A:
undetectable
1gtnH-3ee4A:
undetectable		 1gtnG-3ee4A:
12.95
1gtnH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 1gtnN-3ee4A:
undetectable
1gtnO-3ee4A:
undetectable		 1gtnN-3ee4A:
12.95
1gtnO-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 8 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.35A 1gtnP-3ee4A:
undetectable
1gtnQ-3ee4A:
undetectable		 1gtnP-3ee4A:
12.95
1gtnQ-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.42A 1gtnR-3ee4A:
undetectable
1gtnS-3ee4A:
undetectable		 1gtnR-3ee4A:
12.95
1gtnS-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.42A 1gtnS-3ee4A:
undetectable
1gtnT-3ee4A:
undetectable		 1gtnS-3ee4A:
12.95
1gtnT-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 MET A 231
LEU A 234
LEU A 237
ALA A 238
LEU A 170
 None
None
None
None
MYR  A 315 ( 4.7A)
 1.08A 1gwrA-3ee4A:
undetectable		 1gwrA-3ee4A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		4 / 6 SER A 158
THR A 157
ASN A 238
LEU A 236
 None
None
None
MYR  A 500 (-3.7A)
 1.35A 1mxdA-3fs1A:
undetectable		 1mxdA-3fs1A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 12 SER A 256
VAL A 178
ILE A 175
ILE A 349
ILE A 346
 MYR  A 500 ( 4.1A)
None
None
None
MYR  A 500 (-4.7A)
 0.97A 1qhsA-3fs1A:
undetectable		 1qhsA-3fs1A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 4iqr HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 12 SER A 256
VAL A 178
ILE A 175
ILE A 349
ILE A 346
 MYR  A 401 ( 4.8A)
None
None
None
None
 0.90A 1qhsA-4iqrA:
undetectable		 1qhsA-4iqrA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 12 SER A 256
VAL A 178
ILE A 175
ILE A 349
ILE A 346
 MYR  A 500 ( 4.1A)
None
None
None
MYR  A 500 (-4.7A)
 0.99A 1qhyA-3fs1A:
undetectable		 1qhyA-3fs1A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 4iqr HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 12 SER A 256
VAL A 178
ILE A 175
ILE A 349
ILE A 346
 MYR  A 401 ( 4.8A)
None
None
None
None
 0.93A 1qhyA-4iqrA:
undetectable		 1qhyA-4iqrA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5w7d ACYLOXYACYL
HYDROLASE
(Mus
musculus) 		4 / 8 PHE A 267
ASN A 296
SER A 174
ALA A 265
 PX8  A 610 (-3.1A)
None
MYR  A 611 ( 4.6A)
None
 1.01A 1rqpC-5w7dA:
undetectable		 1rqpC-5w7dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 5w7d ACYLOXYACYL
HYDROLASE
(Mus
musculus) 		4 / 8 PHE A 267
ASN A 296
SER A 174
ALA A 265
 PX8  A 610 (-3.1A)
None
MYR  A 611 ( 4.6A)
None
 1.01A 1rqpA-5w7dA:
undetectable		 1rqpA-5w7dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 1utdA-3ee4A:
undetectable
1utdB-3ee4A:
undetectable		 1utdA-3ee4A:
12.95
1utdB-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 8 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 1utdB-3ee4A:
undetectable
1utdC-3ee4A:
undetectable		 1utdB-3ee4A:
12.95
1utdC-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 1utdC-3ee4A:
undetectable
1utdD-3ee4A:
undetectable		 1utdC-3ee4A:
12.95
1utdD-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.36A 1utdD-3ee4A:
undetectable
1utdE-3ee4A:
undetectable		 1utdD-3ee4A:
12.95
1utdE-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 8 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 1utdF-3ee4A:
undetectable
1utdG-3ee4A:
undetectable		 1utdF-3ee4A:
12.95
1utdG-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 1utdG-3ee4A:
undetectable
1utdH-3ee4A:
undetectable		 1utdG-3ee4A:
12.95
1utdH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 8 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 1utdJ-3ee4A:
undetectable
1utdK-3ee4A:
undetectable		 1utdJ-3ee4A:
12.95
1utdK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.39A 1utdA-3ee4A:
undetectable
1utdK-3ee4A:
undetectable		 1utdA-3ee4A:
12.95
1utdK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 1utdN-3ee4A:
undetectable
1utdO-3ee4A:
undetectable		 1utdN-3ee4A:
12.95
1utdO-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 1utdR-3ee4A:
undetectable
1utdS-3ee4A:
undetectable		 1utdR-3ee4A:
12.95
1utdS-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 1opk PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1
(Mus
musculus) 		5 / 12 CYH A 483
PRO A 484
ILE A 521
SER A 355
VAL A 525
 MYR  A   1 ( 4.5A)
None
None
None
None
 1.14A 1z9hD-1opkA:
undetectable		 1z9hD-1opkA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1wc8 TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT3
(Mus
musculus) 		5 / 10 LEU A 130
GLY A 133
LEU A 131
LEU A  55
ILE A  51
 None
None
None
MYR  A1168 ( 4.9A)
None
 1.05A 2f8dA-1wc8A:
undetectable		 2f8dA-1wc8A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1wc8 TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT3
(Mus
musculus) 		5 / 10 LEU A 130
GLY A 133
LEU A 131
LEU A  55
ILE A  51
 None
None
None
MYR  A1168 ( 4.9A)
None
 1.04A 2f8dB-1wc8A:
undetectable		 2f8dB-1wc8A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 2l90 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
(Mus
musculus) 		4 / 8 TYR A 200
TYR A 160
ARG A 194
VAL A  67
 None
None
MYR  A  21 ( 3.5A)
None
 0.69A 2fl5E-2l90A:
undetectable
2fl5F-2l90A:
undetectable		 2fl5E-2l90A:
22.96
2fl5F-2l90A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 5 ALA A 207
TRP A 392
LEU A 201
ALA A 208
 None
None
None
MYR  A1001 ( 3.9A)
 1.26A 2jstA-1v26A:
undetectable
2jstB-1v26A:
undetectable		 2jstA-1v26A:
10.30
2jstB-1v26A:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ALA A 304
GLY A 302
GLY A 325
THR A 276
VAL A 274
 AMP  A1002 (-3.8A)
MYR  A1001 ( 3.5A)
MYR  A1001 ( 3.8A)
None
None
 1.05A 2okcA-1v26A:
undetectable		 2okcA-1v26A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 4iqr HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 12 LEU A 263
GLY A 222
ALA A 223
VAL A 178
ILE A 259
 None
None
MYR  A 401 ( 3.7A)
None
None
 0.91A 2rkgB-4iqrA:
undetectable		 2rkgB-4iqrA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5w7d ACYLOXYACYL
HYDROLASE
(Mus
musculus) 		4 / 8 PHE A 267
ASN A 296
SER A 174
ALA A 265
 PX8  A 610 (-3.1A)
None
MYR  A 611 ( 4.6A)
None
 0.98A 2v7uA-5w7dA:
undetectable		 2v7uA-5w7dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		5 / 6 LEU A 249
PRO A 237
ALA A 233
LEU A 236
ALA A 272
 None
None
None
MYR  A1001 ( 4.4A)
None
 1.48A 2vcvK-1v26A:
1.3		 2vcvK-1v26A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 1wc8 TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT3
(Mus
musculus) 		5 / 12 ALA A  82
LEU A  60
MET A 144
GLY A 137
LEU A 135
 MYR  A1168 (-3.6A)
None
None
None
None
 0.88A 2yjaB-1wc8A:
undetectable		 2yjaB-1wc8A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 168
SER A 266
ILE A 242
LEU A 241
LEU A 237
 None
None
MYR  A 315 ( 4.8A)
None
None
 1.37A 3adsB-3ee4A:
2.1		 3adsB-3ee4A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3pxp HELIX-TURN-HELIX
DOMAIN PROTEIN
(Chloroflexus
aurantiacus) 		5 / 12 PHE A 161
VAL A 164
PHE A 269
LEU A 272
TYR A 239
 MYR  A 301 (-4.6A)
None
None
None
None
 1.44A 3apvB-3pxpA:
undetectable		 3apvB-3pxpA:
17.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 12 CYH A 179
GLN A 185
LEU A 219
ARG A 226
LEU A 236
 None
None
MYR  A 500 ( 4.0A)
MYR  A 500 (-2.8A)
MYR  A 500 (-3.7A)
 0.83A 3fc6C-3fs1A:
23.8		 3fc6C-3fs1A:
38.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4iqr HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 12 CYH A 179
GLN A 185
LEU A 219
ARG A 226
LEU A 236
 None
MYR  A 401 (-4.8A)
MYR  A 401 ( 4.4A)
MYR  A 401 (-3.8A)
MYR  A 401 (-3.8A)
 0.92A 3fc6C-4iqrA:
23.2		 3fc6C-4iqrA:
31.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2r2i GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Gallus
gallus) 		3 / 3 ILE A 118
PHE A  62
HIS A 176
 None
MYR  A   1 ( 4.7A)
None
 0.51A 3h0aA-2r2iA:
undetectable		 3h0aA-2r2iA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 2k4h HIV-2 MYRISTOYLATED
MATRIX PROTEIN
(Human
immunodeficiency
virus
2) 		5 / 12 LEU A  75
LEU A  21
ILE A  85
LEU A  64
ILE A  60
 None
None
MYR  A   1 ( 3.4A)
None
None
 1.12A 3ijdA-2k4hA:
undetectable		 3ijdA-2k4hA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 2k4h HIV-2 MYRISTOYLATED
MATRIX PROTEIN
(Human
immunodeficiency
virus
2) 		5 / 12 LEU A  75
LEU A  21
ILE A  85
LEU A  64
ILE A  60
 None
None
MYR  A   1 ( 3.4A)
None
None
 1.11A 3ijdB-2k4hA:
undetectable		 3ijdB-2k4hA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3pxp HELIX-TURN-HELIX
DOMAIN PROTEIN
(Chloroflexus
aurantiacus) 		4 / 8 TYR A 258
TYR A 239
PHE A 130
ILE A 126
 MYR  A 301 (-4.5A)
None
None
None
 1.02A 3jz0B-3pxpA:
undetectable		 3jz0B-3pxpA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1bev BOVINE ENTEROVIRUS
COAT PROTEINS VP1 TO
VP4
BOVINE ENTEROVIRUS
COAT PROTEINS VP1 TO
VP4
(Enterovirus
E;
Enterovirus
E) 		3 / 3 ASN 2 203
ASP 2 196
ARG 1 100
 None
None
MYR  1 900 (-4.7A)
 0.84A 3k13A-1bev2:
undetectable		 3k13A-1bev2:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 325
TRP A 234
VAL A 231
 MYR  A1001 ( 3.8A)
MYR  A1001 (-3.5A)
None
 0.70A 3n62B-1v26A:
undetectable		 3n62B-1v26A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 325
TRP A 234
VAL A 231
 MYR  A1001 ( 3.8A)
MYR  A1001 (-3.5A)
None
 0.67A 3n65B-1v26A:
undetectable		 3n65B-1v26A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 325
TRP A 234
VAL A 231
 MYR  A1001 ( 3.8A)
MYR  A1001 (-3.5A)
None
 0.71A 3n66B-1v26A:
undetectable		 3n66B-1v26A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 MET A 231
LEU A 234
LEU A 237
ALA A 238
LEU A 170
 None
None
None
None
MYR  A 315 ( 4.7A)
 1.07A 3olsA-3ee4A:
3.1		 3olsA-3ee4A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 MET A 231
LEU A 234
LEU A 237
ALA A 238
LEU A 170
 None
None
None
None
MYR  A 315 ( 4.7A)
 1.09A 3q95B-3ee4A:
3.1		 3q95B-3ee4A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUM_A_CCSA375_0
(MALTOSE-BINDING
PERIPLASMIC PROTEIN)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 4 GLN A 474
SER A 303
GLY A 441
LYS A 439
 None
None
None
MYR  A1001 ( 2.8A)
 1.32A 3rumA-1v26A:
0.0		 3rumA-1v26A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		6 / 12 LEU A 263
GLY A 222
ALA A 223
VAL A 178
ILE A 338
ILE A 259
 None
None
MYR  A 500 (-3.5A)
None
None
None
 0.97A 3s54A-3fs1A:
undetectable		 3s54A-3fs1A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		6 / 12 LEU A 263
GLY A 222
ALA A 223
VAL A 178
ILE A 338
ILE A 259
 None
None
MYR  A 500 (-3.5A)
None
None
None
 1.06A 3s54B-3fs1A:
undetectable		 3s54B-3fs1A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 5yhj CYTOCHROME P450
(Exiguobacterium
sp.
AT1b) 		5 / 5 LEU A  78
PHE A 167
ARG A 239
PRO A 240
ALA A 243
 None
None
MYR  A 502 (-4.2A)
MYR  A 502 ( 3.7A)
MYR  A 502 (-3.7A)
 0.49A 3vm4A-5yhjA:
58.4		 3vm4A-5yhjA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 2k4h HIV-2 MYRISTOYLATED
MATRIX PROTEIN
(Human
immunodeficiency
virus
2) 		5 / 12 ILE A  85
LEU A  31
LEU A  51
ALA A  37
ILE A  19
 MYR  A   1 ( 3.4A)
None
MYR  A   1 (-3.3A)
None
None
 1.07A 3vrmA-2k4hA:
undetectable		 3vrmA-2k4hA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		4 / 7 LEU A 263
ALA A 223
VAL A 178
ILE A 259
 None
MYR  A 500 (-3.5A)
None
None
 0.87A 3wsjB-3fs1A:
undetectable		 3wsjB-3fs1A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 1opk PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1
(Mus
musculus) 		4 / 5 ASN A 154
LEU A 360
GLU A 513
THR A 364
 None
MYR  A   1 (-4.5A)
None
None
 1.42A 4p6sA-1opkA:
0.0		 4p6sA-1opkA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 ALA A 238
GLY A 168
GLU A 101
ALA A 171
TYR A 175
 None
None
FE  A 317 (-2.5A)
MYR  A 315 ( 3.9A)
None
 1.17A 4pclA-3ee4A:
undetectable		 4pclA-3ee4A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 12 MET A 231
LEU A 234
LEU A 237
ALA A 238
LEU A 170
 None
None
None
None
MYR  A 315 ( 4.7A)
 1.08A 4pxmA-3ee4A:
3.0		 4pxmA-3ee4A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		4 / 7 ALA A 173
LEU A 236
LEU A 235
ILE A 172
 None
MYR  A 500 (-3.7A)
None
None
 0.74A 4ubsA-3fs1A:
undetectable		 4ubsA-3fs1A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA503_1
(PENTALENIC ACID
SYNTHASE)		 4iqr HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		4 / 7 ALA A 173
LEU A 236
LEU A 235
ILE A 172
 None
MYR  A 401 (-3.8A)
None
None
 0.71A 4ubsA-4iqrA:
undetectable		 4ubsA-4iqrA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 11 LEU A 219
GLU A 184
LEU A 186
LEU A 361
LEU A 365
 MYR  A 500 ( 4.0A)
None
None
None
None
 1.10A 4wg0G-3fs1A:
undetectable
4wg0H-3fs1A:
undetectable
4wg0I-3fs1A:
undetectable		 4wg0G-3fs1A:
11.58
4wg0H-3fs1A:
11.58
4wg0I-3fs1A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 11 LEU A 219
GLU A 184
LEU A 186
LEU A 361
LEU A 365
 MYR  A 500 ( 4.0A)
None
None
None
None
 1.04A 4wg0K-3fs1A:
undetectable
4wg0L-3fs1A:
undetectable
4wg0M-3fs1A:
undetectable		 4wg0K-3fs1A:
11.58
4wg0L-3fs1A:
11.58
4wg0M-3fs1A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		6 / 12 LEU A 263
GLY A 222
ALA A 223
VAL A 178
ILE A 338
ILE A 259
 None
None
MYR  A 500 (-3.5A)
None
None
None
 1.03A 5e5jA-3fs1A:
undetectable		 5e5jA-3fs1A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 4iqr HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		6 / 12 LEU A 263
GLY A 222
ALA A 223
VAL A 178
ILE A 338
ILE A 259
 None
None
MYR  A 401 ( 3.7A)
None
None
None
 1.03A 5e5jA-4iqrA:
undetectable		 5e5jA-4iqrA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.39A 5eeuA-3ee4A:
undetectable
5eeuB-3ee4A:
undetectable		 5eeuA-3ee4A:
12.95
5eeuB-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eeuB-3ee4A:
undetectable
5eeuC-3ee4A:
undetectable		 5eeuB-3ee4A:
12.95
5eeuC-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 5eeuC-3ee4A:
undetectable
5eeuD-3ee4A:
undetectable		 5eeuC-3ee4A:
12.95
5eeuD-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eeuD-3ee4A:
undetectable
5eeuE-3ee4A:
undetectable		 5eeuD-3ee4A:
12.95
5eeuE-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 5eeuE-3ee4A:
undetectable
5eeuF-3ee4A:
undetectable		 5eeuE-3ee4A:
12.95
5eeuF-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eeuG-3ee4A:
undetectable
5eeuH-3ee4A:
undetectable		 5eeuG-3ee4A:
12.95
5eeuH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 5eeuH-3ee4A:
undetectable
5eeuI-3ee4A:
undetectable		 5eeuH-3ee4A:
12.95
5eeuI-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5eeuJ-3ee4A:
undetectable
5eeuK-3ee4A:
undetectable		 5eeuJ-3ee4A:
12.95
5eeuK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eeuA-3ee4A:
undetectable
5eeuK-3ee4A:
undetectable		 5eeuA-3ee4A:
12.95
5eeuK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eeuN-3ee4A:
undetectable
5eeuO-3ee4A:
undetectable		 5eeuN-3ee4A:
12.95
5eeuO-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eeuP-3ee4A:
undetectable
5eeuQ-3ee4A:
undetectable		 5eeuP-3ee4A:
12.95
5eeuQ-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eeuR-3ee4A:
undetectable
5eeuS-3ee4A:
undetectable		 5eeuR-3ee4A:
12.95
5eeuS-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eeuS-3ee4A:
undetectable
5eeuT-3ee4A:
undetectable		 5eeuS-3ee4A:
12.95
5eeuT-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 5eeuT-3ee4A:
undetectable
5eeuU-3ee4A:
undetectable		 5eeuT-3ee4A:
12.95
5eeuU-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eeuU-3ee4A:
undetectable
5eeuV-3ee4A:
undetectable		 5eeuU-3ee4A:
12.95
5eeuV-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eevB-3ee4A:
undetectable
5eevC-3ee4A:
undetectable		 5eevB-3ee4A:
12.95
5eevC-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eevC-3ee4A:
undetectable
5eevD-3ee4A:
undetectable		 5eevC-3ee4A:
12.95
5eevD-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eevD-3ee4A:
undetectable
5eevE-3ee4A:
undetectable		 5eevD-3ee4A:
12.95
5eevE-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eevE-3ee4A:
undetectable
5eevF-3ee4A:
undetectable		 5eevE-3ee4A:
12.95
5eevF-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eevG-3ee4A:
undetectable
5eevH-3ee4A:
undetectable		 5eevG-3ee4A:
12.95
5eevH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 5eevH-3ee4A:
undetectable
5eevI-3ee4A:
undetectable		 5eevH-3ee4A:
12.95
5eevI-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5eevJ-3ee4A:
undetectable
5eevK-3ee4A:
undetectable		 5eevJ-3ee4A:
12.95
5eevK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eevA-3ee4A:
undetectable
5eevK-3ee4A:
undetectable		 5eevA-3ee4A:
12.95
5eevK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eevN-3ee4A:
undetectable
5eevO-3ee4A:
undetectable		 5eevN-3ee4A:
12.95
5eevO-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eevP-3ee4A:
undetectable
5eevQ-3ee4A:
undetectable		 5eevP-3ee4A:
12.95
5eevQ-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eevR-3ee4A:
undetectable
5eevS-3ee4A:
undetectable		 5eevR-3ee4A:
12.95
5eevS-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eevS-3ee4A:
undetectable
5eevT-3ee4A:
undetectable		 5eevS-3ee4A:
12.95
5eevT-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.40A 5eevT-3ee4A:
undetectable
5eevU-3ee4A:
undetectable		 5eevT-3ee4A:
12.95
5eevU-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 5eevU-3ee4A:
undetectable
5eevV-3ee4A:
undetectable		 5eevU-3ee4A:
12.95
5eevV-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 5eewB-3ee4A:
undetectable
5eewC-3ee4A:
undetectable		 5eewB-3ee4A:
12.95
5eewC-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eewC-3ee4A:
undetectable
5eewD-3ee4A:
undetectable		 5eewC-3ee4A:
12.95
5eewD-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eewD-3ee4A:
undetectable
5eewE-3ee4A:
undetectable		 5eewD-3ee4A:
12.95
5eewE-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eewE-3ee4A:
undetectable
5eewF-3ee4A:
undetectable		 5eewE-3ee4A:
12.95
5eewF-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eewG-3ee4A:
undetectable
5eewH-3ee4A:
undetectable		 5eewG-3ee4A:
12.95
5eewH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.38A 5eewH-3ee4A:
undetectable
5eewI-3ee4A:
undetectable		 5eewH-3ee4A:
12.95
5eewI-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5eewJ-3ee4A:
undetectable
5eewK-3ee4A:
undetectable		 5eewJ-3ee4A:
12.95
5eewK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eewA-3ee4A:
undetectable
5eewK-3ee4A:
undetectable		 5eewA-3ee4A:
12.95
5eewK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eewN-3ee4A:
undetectable
5eewO-3ee4A:
undetectable		 5eewN-3ee4A:
12.95
5eewO-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eewP-3ee4A:
undetectable
5eewQ-3ee4A:
undetectable		 5eewP-3ee4A:
12.95
5eewQ-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eewR-3ee4A:
undetectable
5eewS-3ee4A:
undetectable		 5eewR-3ee4A:
12.95
5eewS-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eewS-3ee4A:
undetectable
5eewT-3ee4A:
undetectable		 5eewS-3ee4A:
12.95
5eewT-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.40A 5eewT-3ee4A:
undetectable
5eewU-3ee4A:
undetectable		 5eewT-3ee4A:
12.95
5eewU-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 5eewU-3ee4A:
undetectable
5eewV-3ee4A:
undetectable		 5eewU-3ee4A:
12.95
5eewV-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 5eexB-3ee4A:
undetectable
5eexC-3ee4A:
undetectable		 5eexB-3ee4A:
12.95
5eexC-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eexC-3ee4A:
undetectable
5eexD-3ee4A:
undetectable		 5eexC-3ee4A:
12.95
5eexD-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eexD-3ee4A:
undetectable
5eexE-3ee4A:
undetectable		 5eexD-3ee4A:
12.95
5eexE-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eexE-3ee4A:
undetectable
5eexF-3ee4A:
undetectable		 5eexE-3ee4A:
12.95
5eexF-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eexG-3ee4A:
undetectable
5eexH-3ee4A:
undetectable		 5eexG-3ee4A:
12.95
5eexH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eexH-3ee4A:
undetectable
5eexI-3ee4A:
undetectable		 5eexH-3ee4A:
12.95
5eexI-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5eexJ-3ee4A:
undetectable
5eexK-3ee4A:
undetectable		 5eexJ-3ee4A:
12.95
5eexK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eexA-3ee4A:
undetectable
5eexK-3ee4A:
undetectable		 5eexA-3ee4A:
12.95
5eexK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eexN-3ee4A:
undetectable
5eexO-3ee4A:
undetectable		 5eexN-3ee4A:
12.95
5eexO-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eexP-3ee4A:
undetectable
5eexQ-3ee4A:
undetectable		 5eexP-3ee4A:
12.95
5eexQ-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.36A 5eexQ-3ee4A:
undetectable
5eexR-3ee4A:
undetectable		 5eexQ-3ee4A:
12.95
5eexR-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eexR-3ee4A:
undetectable
5eexS-3ee4A:
undetectable		 5eexR-3ee4A:
12.95
5eexS-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eexS-3ee4A:
undetectable
5eexT-3ee4A:
undetectable		 5eexS-3ee4A:
12.95
5eexT-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.40A 5eexT-3ee4A:
undetectable
5eexU-3ee4A:
undetectable		 5eexT-3ee4A:
12.95
5eexU-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 5eexU-3ee4A:
undetectable
5eexV-3ee4A:
undetectable		 5eexU-3ee4A:
12.95
5eexV-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 5eeyB-3ee4A:
undetectable
5eeyC-3ee4A:
undetectable		 5eeyB-3ee4A:
12.95
5eeyC-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eeyC-3ee4A:
undetectable
5eeyD-3ee4A:
undetectable		 5eeyC-3ee4A:
12.95
5eeyD-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eeyD-3ee4A:
undetectable
5eeyE-3ee4A:
undetectable		 5eeyD-3ee4A:
12.95
5eeyE-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eeyE-3ee4A:
undetectable
5eeyF-3ee4A:
undetectable		 5eeyE-3ee4A:
12.95
5eeyF-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eeyG-3ee4A:
undetectable
5eeyH-3ee4A:
undetectable		 5eeyG-3ee4A:
12.95
5eeyH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eeyH-3ee4A:
undetectable
5eeyI-3ee4A:
undetectable		 5eeyH-3ee4A:
12.95
5eeyI-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5eeyJ-3ee4A:
undetectable
5eeyK-3ee4A:
undetectable		 5eeyJ-3ee4A:
12.95
5eeyK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eeyA-3ee4A:
undetectable
5eeyK-3ee4A:
undetectable		 5eeyA-3ee4A:
12.95
5eeyK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eeyN-3ee4A:
undetectable
5eeyO-3ee4A:
undetectable		 5eeyN-3ee4A:
12.95
5eeyO-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eeyP-3ee4A:
undetectable
5eeyQ-3ee4A:
undetectable		 5eeyP-3ee4A:
12.95
5eeyQ-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.36A 5eeyQ-3ee4A:
undetectable
5eeyR-3ee4A:
undetectable		 5eeyQ-3ee4A:
12.95
5eeyR-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eeyR-3ee4A:
undetectable
5eeyS-3ee4A:
undetectable		 5eeyR-3ee4A:
12.95
5eeyS-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eeyS-3ee4A:
undetectable
5eeyT-3ee4A:
undetectable		 5eeyS-3ee4A:
12.95
5eeyT-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.40A 5eeyT-3ee4A:
undetectable
5eeyU-3ee4A:
undetectable		 5eeyT-3ee4A:
12.95
5eeyU-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 5eeyU-3ee4A:
undetectable
5eeyV-3ee4A:
undetectable		 5eeyU-3ee4A:
12.95
5eeyV-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 5eezB-3ee4A:
undetectable
5eezC-3ee4A:
undetectable		 5eezB-3ee4A:
12.95
5eezC-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eezC-3ee4A:
undetectable
5eezD-3ee4A:
undetectable		 5eezC-3ee4A:
12.95
5eezD-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eezD-3ee4A:
undetectable
5eezE-3ee4A:
undetectable		 5eezD-3ee4A:
12.95
5eezE-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eezE-3ee4A:
undetectable
5eezF-3ee4A:
undetectable		 5eezE-3ee4A:
12.95
5eezF-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eezG-3ee4A:
undetectable
5eezH-3ee4A:
undetectable		 5eezG-3ee4A:
12.95
5eezH-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5eezH-3ee4A:
undetectable
5eezI-3ee4A:
undetectable		 5eezH-3ee4A:
12.95
5eezI-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5eezJ-3ee4A:
undetectable
5eezK-3ee4A:
undetectable		 5eezJ-3ee4A:
12.95
5eezK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eezA-3ee4A:
undetectable
5eezK-3ee4A:
undetectable		 5eezA-3ee4A:
12.95
5eezK-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5eezN-3ee4A:
undetectable
5eezO-3ee4A:
undetectable		 5eezN-3ee4A:
12.95
5eezO-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eezP-3ee4A:
undetectable
5eezQ-3ee4A:
undetectable		 5eezP-3ee4A:
12.95
5eezQ-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.36A 5eezQ-3ee4A:
undetectable
5eezR-3ee4A:
undetectable		 5eezQ-3ee4A:
12.95
5eezR-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eezR-3ee4A:
undetectable
5eezS-3ee4A:
undetectable		 5eezR-3ee4A:
12.95
5eezS-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5eezS-3ee4A:
undetectable
5eezT-3ee4A:
undetectable		 5eezS-3ee4A:
12.95
5eezT-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.40A 5eezT-3ee4A:
undetectable
5eezU-3ee4A:
undetectable		 5eezT-3ee4A:
12.95
5eezU-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 5eezU-3ee4A:
undetectable
5eezV-3ee4A:
undetectable		 5eezU-3ee4A:
12.95
5eezV-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 5ef0B-3ee4A:
undetectable
5ef0C-3ee4A:
undetectable		 5ef0B-3ee4A:
12.95
5ef0C-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef0C-3ee4A:
undetectable
5ef0D-3ee4A:
undetectable		 5ef0C-3ee4A:
12.95
5ef0D-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef0D-3ee4A:
undetectable
5ef0E-3ee4A:
undetectable		 5ef0D-3ee4A:
12.95
5ef0E-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef0E-3ee4A:
undetectable
5ef0F-3ee4A:
undetectable		 5ef0E-3ee4A:
12.95
5ef0F-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef0G-3ee4A:
undetectable
5ef0H-3ee4A:
undetectable		 5ef0G-3ee4A:
12.95
5ef0H-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef0H-3ee4A:
undetectable
5ef0I-3ee4A:
undetectable		 5ef0H-3ee4A:
12.95
5ef0I-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5ef0J-3ee4A:
undetectable
5ef0K-3ee4A:
undetectable		 5ef0J-3ee4A:
12.95
5ef0K-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef0A-3ee4A:
undetectable
5ef0K-3ee4A:
undetectable		 5ef0A-3ee4A:
12.95
5ef0K-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef0N-3ee4A:
undetectable
5ef0O-3ee4A:
undetectable		 5ef0N-3ee4A:
12.95
5ef0O-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef0P-3ee4A:
undetectable
5ef0Q-3ee4A:
undetectable		 5ef0P-3ee4A:
12.95
5ef0Q-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.36A 5ef0Q-3ee4A:
undetectable
5ef0R-3ee4A:
undetectable		 5ef0Q-3ee4A:
12.95
5ef0R-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef0R-3ee4A:
undetectable
5ef0S-3ee4A:
undetectable		 5ef0R-3ee4A:
12.95
5ef0S-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef0S-3ee4A:
undetectable
5ef0T-3ee4A:
undetectable		 5ef0S-3ee4A:
12.95
5ef0T-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.40A 5ef0T-3ee4A:
undetectable
5ef0U-3ee4A:
undetectable		 5ef0T-3ee4A:
12.95
5ef0U-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.39A 5ef0U-3ee4A:
undetectable
5ef0V-3ee4A:
undetectable		 5ef0U-3ee4A:
12.95
5ef0V-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 5ef1B-3ee4A:
undetectable
5ef1C-3ee4A:
undetectable		 5ef1B-3ee4A:
12.95
5ef1C-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef1C-3ee4A:
undetectable
5ef1D-3ee4A:
undetectable		 5ef1C-3ee4A:
12.95
5ef1D-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef1D-3ee4A:
undetectable
5ef1E-3ee4A:
undetectable		 5ef1D-3ee4A:
12.95
5ef1E-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef1E-3ee4A:
undetectable
5ef1F-3ee4A:
undetectable		 5ef1E-3ee4A:
12.95
5ef1F-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef1G-3ee4A:
undetectable
5ef1H-3ee4A:
undetectable		 5ef1G-3ee4A:
12.95
5ef1H-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef1H-3ee4A:
undetectable
5ef1I-3ee4A:
undetectable		 5ef1H-3ee4A:
12.95
5ef1I-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5ef1J-3ee4A:
undetectable
5ef1K-3ee4A:
undetectable		 5ef1J-3ee4A:
12.95
5ef1K-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef1A-3ee4A:
undetectable
5ef1K-3ee4A:
undetectable		 5ef1A-3ee4A:
12.95
5ef1K-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef1N-3ee4A:
undetectable
5ef1O-3ee4A:
undetectable		 5ef1N-3ee4A:
12.95
5ef1O-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef1P-3ee4A:
undetectable
5ef1Q-3ee4A:
undetectable		 5ef1P-3ee4A:
12.95
5ef1Q-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.36A 5ef1Q-3ee4A:
undetectable
5ef1R-3ee4A:
undetectable		 5ef1Q-3ee4A:
12.95
5ef1R-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef1R-3ee4A:
undetectable
5ef1S-3ee4A:
undetectable		 5ef1R-3ee4A:
12.95
5ef1S-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef1S-3ee4A:
undetectable
5ef1T-3ee4A:
undetectable		 5ef1S-3ee4A:
12.95
5ef1T-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.40A 5ef1T-3ee4A:
undetectable
5ef1U-3ee4A:
undetectable		 5ef1T-3ee4A:
12.95
5ef1U-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef1U-3ee4A:
undetectable
5ef1V-3ee4A:
undetectable		 5ef1U-3ee4A:
12.95
5ef1V-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 5ef2B-3ee4A:
undetectable
5ef2C-3ee4A:
undetectable		 5ef2B-3ee4A:
12.95
5ef2C-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef2C-3ee4A:
undetectable
5ef2D-3ee4A:
undetectable		 5ef2C-3ee4A:
12.95
5ef2D-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef2D-3ee4A:
undetectable
5ef2E-3ee4A:
undetectable		 5ef2D-3ee4A:
12.95
5ef2E-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 5ef2E-3ee4A:
undetectable
5ef2F-3ee4A:
undetectable		 5ef2E-3ee4A:
12.95
5ef2F-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef2G-3ee4A:
undetectable
5ef2H-3ee4A:
undetectable		 5ef2G-3ee4A:
12.95
5ef2H-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef2H-3ee4A:
undetectable
5ef2I-3ee4A:
undetectable		 5ef2H-3ee4A:
12.95
5ef2I-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5ef2J-3ee4A:
undetectable
5ef2K-3ee4A:
undetectable		 5ef2J-3ee4A:
12.95
5ef2K-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef2A-3ee4A:
undetectable
5ef2K-3ee4A:
undetectable		 5ef2A-3ee4A:
12.95
5ef2K-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef2N-3ee4A:
undetectable
5ef2O-3ee4A:
undetectable		 5ef2N-3ee4A:
12.95
5ef2O-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef2P-3ee4A:
undetectable
5ef2Q-3ee4A:
undetectable		 5ef2P-3ee4A:
12.95
5ef2Q-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.36A 5ef2Q-3ee4A:
undetectable
5ef2R-3ee4A:
undetectable		 5ef2Q-3ee4A:
12.95
5ef2R-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef2R-3ee4A:
undetectable
5ef2S-3ee4A:
undetectable		 5ef2R-3ee4A:
12.95
5ef2S-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef2S-3ee4A:
undetectable
5ef2T-3ee4A:
undetectable		 5ef2S-3ee4A:
12.95
5ef2T-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.40A 5ef2T-3ee4A:
undetectable
5ef2U-3ee4A:
undetectable		 5ef2T-3ee4A:
12.95
5ef2U-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef2U-3ee4A:
undetectable
5ef2V-3ee4A:
undetectable		 5ef2U-3ee4A:
12.95
5ef2V-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.35A 5ef3B-3ee4A:
undetectable
5ef3C-3ee4A:
undetectable		 5ef3B-3ee4A:
12.95
5ef3C-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef3C-3ee4A:
undetectable
5ef3D-3ee4A:
undetectable		 5ef3C-3ee4A:
12.95
5ef3D-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef3D-3ee4A:
undetectable
5ef3E-3ee4A:
undetectable		 5ef3D-3ee4A:
12.95
5ef3E-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.36A 5ef3E-3ee4A:
undetectable
5ef3F-3ee4A:
undetectable		 5ef3E-3ee4A:
12.95
5ef3F-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef3G-3ee4A:
undetectable
5ef3H-3ee4A:
undetectable		 5ef3G-3ee4A:
12.95
5ef3H-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.37A 5ef3H-3ee4A:
undetectable
5ef3I-3ee4A:
undetectable		 5ef3H-3ee4A:
12.95
5ef3I-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 THR A 173
GLY A 270
ALA A 238
THR A 267
ILE A 235
 MYR  A 315 ( 4.9A)
None
None
None
None
 1.34A 5ef3J-3ee4A:
undetectable
5ef3K-3ee4A:
undetectable		 5ef3J-3ee4A:
12.95
5ef3K-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef3A-3ee4A:
undetectable
5ef3K-3ee4A:
undetectable		 5ef3A-3ee4A:
12.95
5ef3K-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef3N-3ee4A:
undetectable
5ef3O-3ee4A:
undetectable		 5ef3N-3ee4A:
12.95
5ef3O-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef3P-3ee4A:
undetectable
5ef3Q-3ee4A:
undetectable		 5ef3P-3ee4A:
12.95
5ef3Q-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.36A 5ef3Q-3ee4A:
undetectable
5ef3R-3ee4A:
undetectable		 5ef3Q-3ee4A:
12.95
5ef3R-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef3R-3ee4A:
undetectable
5ef3S-3ee4A:
undetectable		 5ef3R-3ee4A:
12.95
5ef3S-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.37A 5ef3S-3ee4A:
undetectable
5ef3T-3ee4A:
undetectable		 5ef3S-3ee4A:
12.95
5ef3T-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.40A 5ef3T-3ee4A:
undetectable
5ef3U-3ee4A:
undetectable		 5ef3T-3ee4A:
12.95
5ef3U-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3ee4 PROBABLE
RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 270
ALA A 238
THR A 267
ILE A 235
THR A 173
 None
None
None
None
MYR  A 315 ( 4.9A)
 1.38A 5ef3U-3ee4A:
undetectable
5ef3V-3ee4A:
undetectable		 5ef3U-3ee4A:
12.95
5ef3V-3ee4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 1wc8 TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT3
(Mus
musculus) 		5 / 12 ALA A  82
LEU A  60
MET A 144
GLY A 137
LEU A 135
 MYR  A1168 (-3.6A)
None
None
None
None
 0.79A 5gs4A-1wc8A:
undetectable		 5gs4A-1wc8A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1bev BOVINE ENTEROVIRUS
COAT PROTEINS VP1 TO
VP4
(Enterovirus
E) 		3 / 3 SER 1 244
LEU 1 105
MET 1 109
 None
None
MYR  1 900 ( 4.9A)
 0.87A 5ikrB-1bev1:
undetectable		 5ikrB-1bev1:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		4 / 5 GLU A 475
GLY A 442
SER A 303
GLY A 302
 None
None
None
MYR  A1001 ( 3.5A)
 1.13A 5kprA-1v26A:
undetectable		 5kprA-1v26A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5yhj CYTOCHROME P450
(Exiguobacterium
sp.
AT1b) 		6 / 10 PRO A  71
LEU A  78
ARG A 239
PRO A 240
ALA A 243
PHE A 285
 None
None
MYR  A 502 (-4.2A)
MYR  A 502 ( 3.7A)
MYR  A 502 (-3.7A)
HEM  A 501 ( 3.9A)
 0.66A 5m0oA-5yhjA:
55.8		 5m0oA-5yhjA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5yhj CYTOCHROME P450
(Exiguobacterium
sp.
AT1b) 		5 / 8 LEU A  78
ARG A 239
PRO A 240
ALA A 243
PHE A 285
 None
MYR  A 502 (-4.2A)
MYR  A 502 ( 3.7A)
MYR  A 502 (-3.7A)
HEM  A 501 ( 3.9A)
 0.44A 5m0oC-5yhjA:
55.1		 5m0oC-5yhjA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 3fs1 HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 12 LEU A 263
GLY A 222
ALA A 223
VAL A 178
ILE A 259
 None
None
MYR  A 500 (-3.5A)
None
None
 0.87A 5t8hA-3fs1A:
undetectable		 5t8hA-3fs1A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 4iqr HEPATOCYTE NUCLEAR
FACTOR 4-ALPHA
(Homo
sapiens) 		5 / 12 LEU A 263
GLY A 222
ALA A 223
VAL A 178
ILE A 259
 None
None
MYR  A 401 ( 3.7A)
None
None
 0.90A 5t8hB-4iqrA:
undetectable		 5t8hB-4iqrA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 2r2i GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Gallus
gallus) 		5 / 10 ALA A  78
LEU A  81
VAL A  82
LEU A  97
ILE A 118
 MYR  A   1 (-3.5A)
None
MYR  A   1 ( 4.6A)
None
None
 1.07A 5v02B-2r2iA:
undetectable
5v02R-2r2iA:
7.1		 5v02B-2r2iA:
21.11
5v02R-2r2iA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 301
THR A 394
PRO A 331
 MYR  A1001 ( 3.9A)
None
MYR  A1001 ( 4.6A)
 0.58A 5v5zA-1v26A:
undetectable		 5v5zA-1v26A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 1bev BOVINE ENTEROVIRUS
COAT PROTEINS VP1 TO
VP4
(Enterovirus
E) 		4 / 7 ILE 1  97
LEU 3  25
PHE 3  28
ARG 1 116
 MYR  1 900 ( 4.4A)
None
None
None
 0.92A 5vc0A-1bev1:
0.0		 5vc0A-1bev1:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1wc8 TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT3
(Mus
musculus) 		5 / 7 GLY A 133
LEU A 130
ILE A  51
GLY A  52
LEU A  55
 None
None
None
None
MYR  A1168 ( 4.9A)
 1.30A 5vkqA-1wc8A:
undetectable
5vkqB-1wc8A:
undetectable		 5vkqA-1wc8A:
7.74
5vkqB-1wc8A:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2k4h HIV-2 MYRISTOYLATED
MATRIX PROTEIN
(Human
immunodeficiency
virus
2) 		4 / 6 ILE A  19
ILE A  60
LEU A  51
PHE A  44
 None
None
MYR  A   1 (-3.3A)
None
 0.88A 5vkqB-2k4hA:
undetectable
5vkqC-2k4hA:
undetectable		 5vkqB-2k4hA:
6.68
5vkqC-2k4hA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2k4h HIV-2 MYRISTOYLATED
MATRIX PROTEIN
(Human
immunodeficiency
virus
2) 		4 / 6 ILE A  19
ILE A  60
LEU A  51
PHE A  44
 None
None
MYR  A   1 (-3.3A)
None
 0.90A 5vkqC-2k4hA:
undetectable
5vkqD-2k4hA:
undetectable		 5vkqC-2k4hA:
6.68
5vkqD-2k4hA:
6.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLY A 325
TRP A 234
VAL A 231
 MYR  A1001 ( 3.8A)
MYR  A1001 (-3.5A)
None
 0.70A 5vuoB-1v26A:
undetectable		 5vuoB-1v26A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2r2i GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Gallus
gallus) 		4 / 7 PHE A  62
ILE A  70
LEU A  33
ILE A 177
 MYR  A   1 ( 4.7A)
MYR  A   1 ( 4.7A)
BME  A 301 (-4.1A)
MYR  A   1 ( 4.6A)
 0.84A 6b5vA-2r2iA:
undetectable
6b5vC-2r2iA:
undetectable		 6b5vA-2r2iA:
19.27
6b5vC-2r2iA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2r2i GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Gallus
gallus) 		4 / 7 PHE A  62
ILE A  70
LEU A  33
ILE A 177
 MYR  A   1 ( 4.7A)
MYR  A   1 ( 4.7A)
BME  A 301 (-4.1A)
MYR  A   1 ( 4.6A)
 0.84A 6b5vA-2r2iA:
undetectable
6b5vB-2r2iA:
undetectable		 6b5vA-2r2iA:
19.27
6b5vB-2r2iA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2r2i GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Gallus
gallus) 		4 / 7 PHE A  62
ILE A  70
LEU A  33
ILE A 177
 MYR  A   1 ( 4.7A)
MYR  A   1 ( 4.7A)
BME  A 301 (-4.1A)
MYR  A   1 ( 4.6A)
 0.84A 6b5vC-2r2iA:
undetectable
6b5vD-2r2iA:
undetectable		 6b5vC-2r2iA:
19.27
6b5vD-2r2iA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 2r2i GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1
(Gallus
gallus) 		4 / 7 PHE A  62
ILE A  70
LEU A  33
ILE A 177
 MYR  A   1 ( 4.7A)
MYR  A   1 ( 4.7A)
BME  A 301 (-4.1A)
MYR  A   1 ( 4.6A)
 0.84A 6b5vB-2r2iA:
undetectable
6b5vD-2r2iA:
undetectable		 6b5vB-2r2iA:
19.27
6b5vD-2r2iA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 3pxp HELIX-TURN-HELIX
DOMAIN PROTEIN
(Chloroflexus
aurantiacus) 		4 / 7 ASN A 176
ALA A 173
GLU A 216
LEU A 179
 MYR  A 301 (-3.1A)
None
None
None
 1.02A 6ci6A-3pxpA:
undetectable		 6ci6A-3pxpA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 5zvt C-TERMINUS OF OUTER
CAPSID PROTEIN VP5
(Aquareovirus
C) 		4 / 4 LYS B 191
LEU B 187
ALA B 190
LEU B 186
 MYR  A 101 (-2.4A)
MYR  A 101 (-4.2A)
MYR  A 101 ( 3.7A)
None
 1.29A 6gnrB-5zvtB:
undetectable		 6gnrB-5zvtB:
undetectable