SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MYA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 7 LEU A 403
TYR A 401
ASN A 246
TYR A 180
 None
None
None
MYA  A1001 (-4.3A)
 1.34A 1afsA-3iu1A:
undetectable		 1afsA-3iu1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		4 / 7 LEU A 403
TYR A 401
ASN A 246
TYR A 180
 None
None
None
MYA  A1001 (-4.3A)
 1.34A 1afsB-3iu1A:
undetectable		 1afsB-3iu1A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 GLY A 213
GLY A 214
ILE A 136
ALA A 173
ALA A 140
 None
None
MYA  A   1 ( 4.8A)
None
MYA  A   1 ( 4.8A)
 0.99A 1x7pA-3b96A:
undetectable
1x7pB-3b96A:
undetectable		 1x7pA-3b96A:
19.63
1x7pB-3b96A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 PHE A 219
PHE A 174
ALA A 216
ILE A 144
LEU A 165
 None
MYA  A   1 (-4.8A)
None
MYA  A   1 (-4.9A)
None
 1.16A 2bjfA-3b96A:
undetectable		 2bjfA-3b96A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 PHE A 219
PHE A 174
ILE A 144
ILE A 296
LEU A 165
 None
MYA  A   1 (-4.8A)
MYA  A   1 (-4.9A)
None
None
 1.10A 2bjfA-3b96A:
undetectable		 2bjfA-3b96A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 ALA A 376
ALA A 293
PHE A 174
PHE A 290
MET A 438
 None
None
MYA  A   1 (-4.8A)
None
None
 1.22A 2nyrA-3b96A:
undetectable		 2nyrA-3b96A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		4 / 6 GLY A 139
GLY A 128
PHE A 418
PHE A 421
 MYA  A   1 ( 3.8A)
None
None
MYA  A   1 ( 3.7A)
 0.99A 2qx6A-3b96A:
undetectable
2qx6B-3b96A:
undetectable		 2qx6A-3b96A:
16.92
2qx6B-3b96A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 PHE A 219
PHE A 174
ILE A 144
ILE A 296
LEU A 165
 None
MYA  A   1 (-4.8A)
MYA  A   1 (-4.9A)
None
None
 1.13A 2rlcA-3b96A:
undetectable		 2rlcA-3b96A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 PHE A 421
LEU A 104
ALA A 101
VAL A 134
GLY A 133
 MYA  A   1 ( 3.7A)
None
None
None
None
 1.02A 2ve3A-3b96A:
0.4		 2ve3A-3b96A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 10 ASN A 212
VAL A 171
GLY A 168
THR A 137
LEU A 138
 None
None
None
None
MYA  A   1 ( 4.6A)
 1.18A 3bexA-3b96A:
undetectable
3bexB-3b96A:
undetectable		 3bexA-3b96A:
18.65
3bexB-3b96A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 ASN A 212
VAL A 171
GLY A 168
THR A 137
LEU A 138
 None
None
None
None
MYA  A   1 ( 4.6A)
 1.17A 3bexC-3b96A:
undetectable
3bexD-3b96A:
undetectable		 3bexC-3b96A:
18.65
3bexD-3b96A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 THR A 137
LEU A 138
ASN A 212
VAL A 171
GLY A 168
 None
MYA  A   1 ( 4.6A)
None
None
None
 1.16A 3bexE-3b96A:
undetectable
3bexF-3b96A:
undetectable		 3bexE-3b96A:
18.65
3bexF-3b96A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 ASN A 212
VAL A 171
GLY A 168
THR A 137
LEU A 138
 None
None
None
None
MYA  A   1 ( 4.6A)
 1.17A 3bf1A-3b96A:
undetectable
3bf1B-3b96A:
undetectable		 3bf1A-3b96A:
18.65
3bf1B-3b96A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_B_PAUB248_0
(TYPE III
PANTOTHENATE KINASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 12 THR A 137
LEU A 138
ASN A 212
VAL A 171
GLY A 168
 None
MYA  A   1 ( 4.6A)
None
None
None
 1.16A 3bf1A-3b96A:
undetectable
3bf1B-3b96A:
undetectable		 3bf1A-3b96A:
18.65
3bf1B-3b96A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 ASN A 212
VAL A 171
GLY A 168
THR A 137
LEU A 138
 None
None
None
None
MYA  A   1 ( 4.6A)
 1.20A 3bf1C-3b96A:
undetectable
3bf1D-3b96A:
undetectable		 3bf1C-3b96A:
18.65
3bf1D-3b96A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 THR A 137
LEU A 138
ASN A 212
VAL A 171
GLY A 168
 None
MYA  A   1 ( 4.6A)
None
None
None
 1.17A 3bf1C-3b96A:
undetectable
3bf1D-3b96A:
undetectable		 3bf1C-3b96A:
18.65
3bf1D-3b96A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 ASN A 212
VAL A 171
GLY A 168
THR A 137
LEU A 138
 None
None
None
None
MYA  A   1 ( 4.6A)
 1.16A 3bf1E-3b96A:
undetectable
3bf1F-3b96A:
undetectable		 3bf1E-3b96A:
18.65
3bf1F-3b96A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		5 / 11 THR A 137
LEU A 138
ASN A 212
VAL A 171
GLY A 168
 None
MYA  A   1 ( 4.6A)
None
None
None
 1.14A 3bf1E-3b96A:
undetectable
3bf1F-3b96A:
undetectable		 3bf1E-3b96A:
18.65
3bf1F-3b96A:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE
(Homo
sapiens) 		4 / 8 GLY A 303
MET A 294
PHE A 222
PHE A 174
 MYA  A   1 ( 4.9A)
MYA  A   1 ( 4.6A)
None
MYA  A   1 (-4.8A)
 1.08A 3ko0D-3b96A:
undetectable
3ko0E-3b96A:
undetectable		 3ko0D-3b96A:
12.27
3ko0E-3b96A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 12 GLY A 224
GLY A 213
LEU A 248
THR A 174
LEU A 175
 None
None
MYA  A1001 (-4.1A)
None
None
 1.04A 3mteB-3iu1A:
undetectable		 3mteB-3iu1A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 3iu1 GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE 1
(Homo
sapiens) 		5 / 12 GLY A 224
GLY A 213
LEU A 248
THR A 174
LEU A 175
 None
None
MYA  A1001 (-4.1A)
None
None
 1.03A 3p2kB-3iu1A:
undetectable		 3p2kB-3iu1A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 4cgn GLYCYLPEPTIDE
N-TETRADECANOYLTRANS
FERASE
(Leishmania
major) 		5 / 10 LEU A  76
LEU A  75
TYR A  80
ALA A 127
ILE A  72
 None
None
MYA  A1001 (-4.6A)
None
None
 1.16A 4xj7C-4cgnA:
undetectable
4xj7D-4cgnA:
undetectable		 4xj7C-4cgnA:
20.38
4xj7D-4cgnA:
20.38