SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MXN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3gdn R-OXYNITRILE LYASE
ISOENZYME 1
(Prunus
dulcis) 		5 / 11 GLY A 506
ILE A 254
GLY A 472
PHE A 490
PHE A 501
 None
None
None
MXN  A 531 (-3.7A)
MXN  A 531 (-3.8A)
 1.11A 4qoiA-3gdnA:
undetectable
4qoiB-3gdnA:
2.5		 4qoiA-3gdnA:
18.60
4qoiB-3gdnA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_NPSA602_1
(SERUM ALBUMIN)		 3gdn R-OXYNITRILE LYASE
ISOENZYME 1
(Prunus
dulcis) 		5 / 12 LEU A 465
PHE A 474
LEU A 505
TYR A 502
SER A 125
 None
None
None
FAD  A 522 (-4.5A)
MXN  A 531 (-4.1A)
 1.44A 5dbyA-3gdnA:
0.5		 5dbyA-3gdnA:
20.31