SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MVC'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 4wn5 HYPOXIA-INDUCIBLE
FACTOR 3-ALPHA
(Homo
sapiens) 		4 / 8 ILE A 258
SER A 265
ASP A 268
SER A 310
 MVC  A 402 ( 4.8A)
None
None
None
 0.74A 2cdqA-4wn5A:
undetectable		 2cdqA-4wn5A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 4wn5 HYPOXIA-INDUCIBLE
FACTOR 3-ALPHA
(Homo
sapiens) 		4 / 6 PHE A 306
ARG A 305
LEU A 314
ALA A 262
 MVC  A 402 (-2.8A)
None
None
None
 1.03A 6b89B-4wn5A:
undetectable		 6b89B-4wn5A:
23.15