SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MR9'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
3 / 3 MET A 952
LEU A 955
SER A 956
None
MR9  A 301 (-4.4A)
None
0.63A 1ee2A-2p4iA:
undetectable
1ee2A-2p4iA:
21.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.31A 1iepA-2p4iA:
10.0
1iepA-2p4iA:
37.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
3 / 3 ASP A 982
PHE A 960
ARG A 987
MR9  A 301 (-4.2A)
MR9  A 301 ( 4.7A)
None
0.83A 2a3aA-2p4iA:
undetectable
2a3aA-2p4iA:
22.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.35A 2hyyA-2p4iA:
23.8
2hyyA-2p4iA:
36.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.39A 2hyyB-2p4iA:
23.8
2hyyB-2p4iA:
36.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.45A 2hyyC-2p4iA:
23.9
2hyyC-2p4iA:
36.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
3 / 3 HIS A 962
ILE A 885
LEU A 876
MR9  A 301 (-4.5A)
MR9  A 301 ( 4.5A)
MR9  A 301 ( 4.5A)
0.76A 2kceA-2p4iA:
undetectable
2kceA-2p4iA:
23.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
8 / 12 VAL A 838
ALA A 853
LYS A 855
TYR A 904
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.6A)
MR9  A 301 (-3.8A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.59A 2oiqA-2p4iA:
24.0
2oiqA-2p4iA:
33.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 VAL A 838
ALA A 853
LYS A 855
TYR A 904
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.6A)
MR9  A 301 (-3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.54A 2pl0A-2p4iA:
22.7
2pl0A-2p4iA:
33.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 12 LEU A 910
LEU A 914
ILE A 980
SER A1033
PRO A1038
None
None
MR9  A 301 (-4.6A)
None
None
1.14A 3aqiB-2p4iA:
undetectable
3aqiB-2p4iA:
21.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 ALA A 853
VAL A 875
GLY A 908
HIS A 962
LEU A 971
ALA A 981
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.8A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
0.40A 3cs9A-2p4iA:
23.9
3cs9A-2p4iA:
37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_B_NILB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
VAL A 875
GLY A 908
HIS A 962
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.8A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.45A 3cs9B-2p4iA:
24.3
3cs9B-2p4iA:
37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 12 ALA A 853
PHE A 960
HIS A 962
ALA A 981
ASP A 982
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.7A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.51A 3cs9C-2p4iA:
24.0
3cs9C-2p4iA:
37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 12 ALA A 853
VAL A 875
HIS A 962
ALA A 981
ASP A 982
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.40A 3cs9C-2p4iA:
24.0
3cs9C-2p4iA:
37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 12 ALA A 853
VAL A 875
GLY A 908
HIS A 962
ALA A 981
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.8A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
0.34A 3cs9D-2p4iA:
23.6
3cs9D-2p4iA:
37.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
4 / 6 VAL A 838
LYS A 855
LEU A 971
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 ( 4.6A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.2A)
0.61A 3cs9D-2p4iA:
23.6
3cs9D-2p4iA:
37.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 VAL A 838
ALA A 853
LEU A 879
LEU A 876
ILE A 886
HIS A 962
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 (-4.1A)
MR9  A 301 ( 4.5A)
MR9  A 301 (-4.0A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.2A)
1.36A 3gcsA-2p4iA:
17.3
3gcsA-2p4iA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
LEU A 876
ILE A 886
HIS A 962
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.5A)
MR9  A 301 (-4.0A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.2A)
0.82A 3gp0A-2p4iA:
6.6
3gp0A-2p4iA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
LEU A 879
LEU A 876
ILE A 886
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 (-4.1A)
MR9  A 301 ( 4.5A)
MR9  A 301 (-4.0A)
MR9  A 301 (-4.2A)
1.32A 3hegA-2p4iA:
11.6
3hegA-2p4iA:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 12 VAL A 838
ALA A 853
LYS A 855
LEU A 876
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.6A)
MR9  A 301 ( 4.5A)
MR9  A 301 (-4.2A)
0.76A 3hegA-2p4iA:
11.6
3hegA-2p4iA:
25.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_A_0LIA1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
ILE A 902
HIS A 962
LEU A 971
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-4.1A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.45A 3ik3A-2p4iA:
23.5
3ik3A-2p4iA:
38.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_B_0LIB2_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
ILE A 902
HIS A 962
LEU A 971
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-4.1A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.54A 3ik3B-2p4iA:
23.3
3ik3B-2p4iA:
38.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.34A 3k5vA-2p4iA:
15.2
3k5vA-2p4iA:
37.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.35A 3k5vB-2p4iA:
17.9
3k5vB-2p4iA:
37.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.35A 3ms9B-2p4iA:
23.6
3ms9B-2p4iA:
37.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_1
(TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.36A 3mssB-2p4iA:
13.1
3mssB-2p4iA:
37.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 VAL A 838
ALA A 853
TYR A 904
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 (-3.8A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.53A 3oezA-2p4iA:
23.8
3oezA-2p4iA:
33.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 VAL A 838
ALA A 853
VAL A 875
TYR A 904
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.8A)
MR9  A 301 (-3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.83A 3oezB-2p4iA:
24.0
3oezB-2p4iA:
33.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 ALA A 853
GLY A 908
HIS A 962
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.45A 3oxzA-2p4iA:
24.0
3oxzA-2p4iA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PYY_A_STIA3_1
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
GLY A 908
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.30A 3pyyA-2p4iA:
24.0
3pyyA-2p4iA:
36.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
9 / 12 VAL A 838
ALA A 853
LEU A 876
ILE A 886
TYR A 904
ALA A 905
LEU A 955
HIS A 962
ALA A 981
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.5A)
MR9  A 301 (-4.0A)
MR9  A 301 (-3.8A)
MR9  A 301 (-3.6A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
0.90A 3rgfA-2p4iA:
18.9
3rgfA-2p4iA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 12 LEU A 910
LEU A 914
ILE A 980
SER A1033
PRO A1038
None
None
MR9  A 301 (-4.6A)
None
None
1.23A 3w1wA-2p4iA:
undetectable
3w1wA-2p4iA:
21.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_A_0LIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
LEU A 955
HIS A 962
LEU A 971
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.62A 3zosA-2p4iA:
12.4
3zosA-2p4iA:
33.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 9 LEU A 879
ILE A 885
ILE A 886
TYR A 904
ILE A 980
MR9  A 301 (-4.1A)
MR9  A 301 ( 4.5A)
MR9  A 301 (-4.0A)
MR9  A 301 (-3.8A)
MR9  A 301 (-4.6A)
0.72A 3zosA-2p4iA:
13.6
3zosA-2p4iA:
33.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
8 / 12 ALA A 853
ILE A 886
LEU A 955
HIS A 962
LEU A 971
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-4.0A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.67A 3zosB-2p4iA:
12.2
3zosB-2p4iA:
33.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
LEU A 955
HIS A 962
ARG A 963
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-3.5A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
None
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.78A 3zosB-2p4iA:
12.2
3zosB-2p4iA:
33.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 VAL A 838
ALA A 853
ILE A 886
TYR A 904
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 (-4.0A)
MR9  A 301 (-3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.62A 4bkjA-2p4iA:
21.8
4bkjA-2p4iA:
33.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_B_STIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 VAL A 838
ALA A 853
ILE A 886
LEU A 971
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 (-4.0A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.55A 4bkjB-2p4iA:
9.1
4bkjB-2p4iA:
33.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
4 / 5 VAL A 838
ILE A 885
TYR A 904
ILE A 980
MR9  A 301 (-4.6A)
MR9  A 301 ( 4.5A)
MR9  A 301 (-3.8A)
MR9  A 301 (-4.6A)
0.80A 4c8bA-2p4iA:
9.8
4c8bA-2p4iA:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
ILE A 885
HIS A 962
LEU A 971
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.77A 4c8bB-2p4iA:
11.4
4c8bB-2p4iA:
25.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 VAL A 838
ALA A 853
TYR A 904
LEU A 971
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 (-3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.45A 4csvA-2p4iA:
24.1
4csvA-2p4iA:
38.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 12 ALA A 853
ARG A 963
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
None
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
1.11A 4qrcA-2p4iA:
27.9
4qrcA-2p4iA:
43.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QRC_A_0LIA802_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 12 ALA A 853
LEU A 955
ARG A 963
ALA A 981
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-4.4A)
None
MR9  A 301 (-3.2A)
MR9  A 301 (-4.4A)
0.68A 4qrcA-2p4iA:
27.9
4qrcA-2p4iA:
43.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 8 VAL A 838
LYS A 855
ALA A 905
HIS A 962
LEU A 971
MR9  A 301 (-4.6A)
MR9  A 301 ( 4.6A)
MR9  A 301 (-3.6A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
0.82A 4qrcA-2p4iA:
27.9
4qrcA-2p4iA:
43.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 8 VAL A 838
LYS A 855
ILE A 886
HIS A 962
LEU A 971
MR9  A 301 (-4.6A)
MR9  A 301 ( 4.6A)
MR9  A 301 (-4.0A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
1.11A 4qrcA-2p4iA:
27.9
4qrcA-2p4iA:
43.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
ALA A 905
HIS A 962
LEU A 971
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-3.6A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.47A 4tyjA-2p4iA:
17.4
4tyjA-2p4iA:
43.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U0I_A_0LIA1001_2
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
LEU A 876
GLY A 908
HIS A 962
LEU A 971
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.5A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.80A 4u0iA-2p4iA:
23.8
4u0iA-2p4iA:
39.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
LEU A 955
HIS A 962
LEU A 971
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.49A 4uxqA-2p4iA:
26.8
4uxqA-2p4iA:
44.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
4 / 7 LYS A 855
ILE A 886
ALA A 905
ILE A 980
MR9  A 301 ( 4.6A)
MR9  A 301 (-4.0A)
MR9  A 301 (-3.6A)
MR9  A 301 (-4.6A)
0.69A 4uxqA-2p4iA:
26.8
4uxqA-2p4iA:
44.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
ALA A 905
LEU A 955
HIS A 962
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-3.6A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.55A 4v01A-2p4iA:
27.1
4v01A-2p4iA:
42.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 ALA A 905
LEU A 955
HIS A 962
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.6A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
1.36A 4v01A-2p4iA:
27.1
4v01A-2p4iA:
42.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 9 VAL A 838
LYS A 855
ILE A 886
TYR A 904
LEU A 971
ILE A 980
MR9  A 301 (-4.6A)
MR9  A 301 ( 4.6A)
MR9  A 301 (-4.0A)
MR9  A 301 (-3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.6A)
1.03A 4v01A-2p4iA:
27.1
4v01A-2p4iA:
42.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
ALA A 905
LEU A 955
HIS A 962
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-3.6A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.61A 4v01B-2p4iA:
13.0
4v01B-2p4iA:
42.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 ALA A 905
LEU A 955
HIS A 962
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.6A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
1.36A 4v01B-2p4iA:
13.0
4v01B-2p4iA:
42.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 VAL A 838
ALA A 853
ALA A 905
LEU A 955
HIS A 962
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 (-3.6A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.55A 4v04A-2p4iA:
25.4
4v04A-2p4iA:
42.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
4 / 8 ILE A 886
LEU A 971
ILE A 980
PHE A 983
MR9  A 301 (-4.0A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.6A)
MR9  A 301 (-4.4A)
0.70A 4v04A-2p4iA:
25.4
4v04A-2p4iA:
42.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
4 / 8 TYR A 904
LEU A 971
ILE A 980
PHE A 983
MR9  A 301 (-3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.6A)
MR9  A 301 (-4.4A)
0.77A 4v04A-2p4iA:
25.4
4v04A-2p4iA:
42.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
ALA A 905
LEU A 955
HIS A 962
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.5A)
MR9  A 301 (-3.6A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
0.51A 4v04B-2p4iA:
26.4
4v04B-2p4iA:
42.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 ALA A 905
LEU A 955
HIS A 962
ALA A 981
ASP A 982
PHE A 983
MR9  A 301 (-3.6A)
MR9  A 301 (-4.4A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
MR9  A 301 (-4.4A)
1.35A 4v04B-2p4iA:
26.4
4v04B-2p4iA:
42.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 10 ALA A 853
ILE A 902
GLY A 908
LEU A 971
ALA A 981
MR9  A 301 (-3.5A)
MR9  A 301 (-4.1A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
0.67A 5ajqB-2p4iA:
19.1
5ajqB-2p4iA:
28.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
5 / 12 ALA A 853
ILE A 902
PHE A 960
ALA A 981
ASP A 982
MR9  A 301 (-3.5A)
MR9  A 301 (-4.1A)
MR9  A 301 ( 4.7A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.65A 5mo4A-2p4iA:
22.2
5mo4A-2p4iA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
7 / 12 ALA A 853
VAL A 875
ILE A 902
HIS A 962
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.8A)
MR9  A 301 (-4.1A)
MR9  A 301 (-4.5A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.50A 5mo4A-2p4iA:
22.2
5mo4A-2p4iA:
27.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
TYR A 904
ALA A 905
GLY A 908
ALA A 981
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 (-3.8A)
MR9  A 301 (-3.6A)
MR9  A 301 ( 3.8A)
MR9  A 301 (-3.2A)
0.69A 5zv2A-2p4iA:
25.1
5zv2A-2p4iA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
LYS A 855
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.6A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.58A 6hd4A-2p4iA:
12.2
6hd4A-2p4iA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)
2p4i ANGIOPOIETIN-1
RECEPTOR

(Homo
sapiens)
6 / 12 VAL A 838
ALA A 853
LYS A 855
LEU A 971
ALA A 981
ASP A 982
MR9  A 301 (-4.6A)
MR9  A 301 (-3.5A)
MR9  A 301 ( 4.6A)
MR9  A 301 (-4.5A)
MR9  A 301 (-3.2A)
MR9  A 301 (-4.2A)
0.56A 6hd4B-2p4iA:
23.9
6hd4B-2p4iA:
12.80