SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'MQE'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		3 / 3 LEU L 226
HIS L 264
ILE L 263
 None
FE  L1005 (-4.4A)
MQE  L1004 ( 4.5A)
 0.60A 1s9pB-5yq7L:
undetectable		 1s9pB-5yq7L:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 11 THR M 545
ILE M 546
GLY M 543
HIS M 589
ILE M 588
 MQE  M 701 (-4.0A)
None
None
FE  L1005 (-3.2A)
MQE  M 701 (-4.4A)
 1.29A 2y7kA-5yq7M:
undetectable		 2y7kA-5yq7M:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 12 THR M 545
ILE M 546
GLY M 543
HIS M 589
ILE M 588
 MQE  M 701 (-4.0A)
None
None
FE  L1005 (-3.2A)
MQE  M 701 (-4.4A)
 1.20A 2y7kC-5yq7M:
undetectable		 2y7kC-5yq7M:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		5 / 10 THR M 545
ILE M 546
GLY M 543
HIS M 589
ILE M 588
 MQE  M 701 (-4.0A)
None
None
FE  L1005 (-3.2A)
MQE  M 701 (-4.4A)
 1.28A 2y7pA-5yq7M:
undetectable		 2y7pA-5yq7M:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_C_SALC1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5yq7 PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 7 THR M 545
ILE M 546
GLY M 543
HIS M 589
 MQE  M 701 (-4.0A)
None
None
FE  L1005 (-3.2A)
 0.83A 2y7wC-5yq7M:
undetectable		 2y7wC-5yq7M:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii) 		4 / 7 ILE M 588
HIS M 542
LEU M 538
GLY L 230
 MQE  M 701 (-4.4A)
FE  L1005 ( 3.0A)
MQE  M 701 ( 4.9A)
None
 0.90A 4z69A-5yq7M:
2.9		 4z69A-5yq7M:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		5 / 12 HIS L 264
LEU M 539
ILE L 263
HIS L 229
HIS M 589
 FE  L1005 (-4.4A)
None
MQE  L1004 ( 4.5A)
FE  L1005 (-3.1A)
FE  L1005 (-3.2A)
 1.14A 6n91A-5yq7L:
undetectable		 6n91A-5yq7L:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 5yq7 PRECURSOR FOR L
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
PRECURSOR FOR M
SUBUNITS OF
PHOTOSYNTHETIC
REACTION CENTER
(Roseiflexus
castenholzii;
Roseiflexus
castenholzii) 		5 / 12 HIS L 264
LEU M 539
ILE L 263
HIS L 229
HIS M 589
 FE  L1005 (-4.4A)
None
MQE  L1004 ( 4.5A)
FE  L1005 (-3.1A)
FE  L1005 (-3.2A)
 1.15A 6n91B-5yq7L:
undetectable		 6n91B-5yq7L:
19.54